LIPIKIND AS 20 Capsule 10's

Introduction About LIPIKIND AS 20 CAPSULE

LIPIKIND AS 20 Capsule is used for the management of dyslipidemia associated with atherosclerotic arterial disease with risk of myocardial infarction, stroke or peripheral vascular disease. It is a combination of Atorvastatin and Aspirin which belongs to the group of medicines known as Statins and Non-steroid anti-inflammatory agents respectively. LIPIKIND AS 20 Capsule works by blocking an enzyme required in the body to make cholesterol. It lowers the bad cholesterol (LDL), and triglycerides and raises the good cholesterol (HDL) and also decreases the formation of harmful blood clots.

LIPIKIND AS 20 CAPSULE is not recommended for use in patients hypoprothrombinaemia, haemophilia and active peptic ulceration. It should be used with caution in patients with rhabdomyolysis, hypothyroidism, hereditary muscular disorders or muscular toxicity with a statin or fibrate. LIPIKIND AS 20 CAPSULE is generally not recommended for use in pregnant women. Contact your doctor before taking. LIPIKIND AS 20 CAPSULE is generally not recommended for use in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking the medicine. LIPIKIND AS 20 CAPSULE is not recommended for use in children. Contact your doctor before taking.

Efficacy and safety in patients older than 70 years of age using recommended doses are similar to those seen in the general population. Consult your doctor before taking LIPIKIND AS 20 CAPSULE. It is well tolerated, but the main side-effects are muscle pain, diarrhoea, nausea, joint pain, minor bleedings and allergic reactions. Contact your doctor if any of the above side effects worsen or persists for a longer duration.

Uses Of LIPIKIND AS 20 CAPSULE

LIPIKIND AS 20 Capsule is used in the management of:

• dyslipidemia
• hypertriglyceridemia
• patient at high risk of heart disease

How LIPIKIND AS 20 CAPSULE Works

LIPIKIND AS 20 CAPSULE is a combination of Atorvastatin and Aspirin. Atorvastatin is a lipid-lowering agents blocks an enzyme required in the body to make cholesterol. It lowers the bad cholesterol (LDL), and triglycerides and raises the good cholesterol (HDL). Aspirin is a non-steroidal anti-inflammatory agent (NSAID) with anti-platelet action. It helps to manage the platelets from sticking together and decreases the formation of harmful blood clots.

How to use LIPIKIND AS 20 CAPSULE

Take LIPIKIND AS 20 CAPSULE as advised by your physician. It can be taken with or without food. Swallow LIPIKIND AS 20 CAPSULE with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

Side Effects Of LIPIKIND AS 20 CAPSULE

How To Manage Side Effects

Diarrhea

Drink lots of fluids, such as water or fruit juices to keep you hydrated. Do not take any medicine on your own for manageing diarrhea. Contact your doctor if the symptom did not improve.

Nausea And Vomiting

Take this medicine with, or just after meals. Stick to simple meals. Avoid eating oily or spicy foods.

Warning & Precautions

Pregnancy

Contraindicated

LIPIKIND AS 20 CAPSULE is not recommended for use in pregnant women. Contact your doctor before taking the medicine.

Breastfeeding

Contraindicated

LIPIKIND AS 20 CAPSULE is not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking the medicine.

Alcohol

Consult your doctor

LIPIKIND AS 20 CAPSULE should be used with caution in patients who consume substantial quantities of alcohol. Consult your doctor before taking the medicine.

Kidney

Use with Caution

LIPIKIND AS 20 CAPSULE should be used with caution in patients with kidney disease. Contact your doctor before taking.

Liver

Consult your doctor

LIPIKIND AS 20 CAPSULE is not recommended for use in patients with severe liver disease. It should be used with caution in patients with acute liver diseases. Contact your doctor before taking the medicine.

Allergy

Contraindicated

Do not take LIPIKIND AS 20 CAPSULE if you are allergic to Atorvastatin or Aspirin or any other ingredients of this medicine.

Heart Disease

Use with Caution

LIPIKIND AS 20 CAPSULE should be used with caution in patients with prior hemorrhagic stroke or lacunar infarct. Consult your doctor before taking the medicine.

Use In Pediatrics

Monitoring required

LIPIKIND AS 20 CAPSULE is not recommended for use in children and adolescents below 16 years of age, unless specifically indicated for Kawasaki's disease. Your doctor will give the right dose depending on your child’s age, body weight and disease condition. Contact your doctor before giving this medicine.

Use In Geriatrics

Consult your doctor

Efficacy and safety in patients older than 70 years of age using recommended doses are similar to those seen in the general population. Consult your doctor before taking LIPIKIND AS 20 CAPSULE.

Interactions

A. Drug-Drug interactions:

Before taking LIPIKIND AS 20 CAPSULE inform your doctor if you are taking any of the following:

• CYP3A4 inhibitors (Ex. ciclosporin, telithromycin, clarithromycin, delavirdine, stiripentol, ketoconazole, voriconazole, itraconazole, posaconazole)
• HIV protease inhibitors (Ex. ritonavir, lopinavir, atazanavir, indinavir, darunavir)
• CYP3A4 inducers (Ex. efavirenz, rifampin, St. John's Wort)
• Gemfibrozil and fibric acid derivatives
• Selective cholesterol-absorption inhibitors (Ex. ezetimibe)
• Cardiac glycosides (Ex. digoxin)
• Oral contraceptives
• Coumarin derivatives (Ex. warfarin)
• Oral hypoglycaemic agents
• Anti-convulsant (Ex. Phenytoin, Sodium valproate)
• Corticosteroids
• Carbonic anhydrase inhibitors (Ex. acetazolamide and salicylates)

Overdosage:

If you or anyone else accidentally took too much of LIPIKIND AS 20 CAPSULE, consult your doctor immediately. Symptoms of overdose include vomiting, dehydration, tinnitus, vertigo, deafness, sweating, warm extremities with bounding pulses, increased respiratory rate and hyperventilation.

Synopsis

More Information

• Keep LIPIKIND AS 20 CAPSULE out of reach of children
• Store LIPIKIND AS 20 CAPSULE below 25°C

FAQs About LIPIKIND AS 20 CAPSULE

References

1. KD. Tripathi. HYPOLIPI DAEM IC DRUGS. Essentials of medical pharmacology. Seventh edition. 2013. Page-685.

2. Nirmal Ghati, Ambuj Roy, Sushma Bhatnagar, Sumit Bhati, Sudha Bhushan, Manjit Mahendran, Abhishek Thakur, Pawan Tiwari, Tanima Dwivedi, Kalaivani Mani, Ritu Gupta, Anant Mohan, Rakesh Garg, Anita Saxena, Randeep Guleria, and Siddharthan Deepti. Atorvastatin and Aspirin as Adjuvant Therapy in Patients with SARS-CoV-2 Infection: A structured summary of a study protocol for a randomised controlled trial. October 30, 2020. [Accessed on May 16, 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598224/

3. Innovative pharma. [Accessed on May 16, 2024] https://www.innovativepharma.in/product/atrosure-a-20-75-capsules/

4. Leeford Healthcare. [Accessed on May 16, 2024] https://www.leeford.in/product/586/cardiozen-20-asp

5. Torrent Pharmaceuticals Ltd. [Accessed on May 16, 2024] https://www.torrentpharma.com/pi/storage/Upload/PI_Sheet/2444.pdf

Useful Diagnostic Tests

• Cardiac Risk Profile
• C Reactive Protein (CRP)
• Lipid Profile Test/Cholesterol-Total, Serum
• Lipid Profile-Extended
• HDL Cholesterol Direct
• Cardiac Risk Markers
• Cholesterol-Total, Serum

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)

Last updated on 18 May 2024 | 10:26 AM(IST)