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Introduction About LIDOFIX GEL
LIDOFIX GEL contains Lignocaine, which belongs to the group of medicines called Local anaesthetic agents. It causes numbness of body parts at sites where it has been applied. It is used for temporary relief of pain and discomfort associated with skin abrasions, sun burns, insect bites, sore nipples, haemorrhoids (piles), anal fissures, bed sores, shingles, or cold sores (painful skin rash or blisters around the mouth due to viral infections).
It can also be used to relieve pain following circumcision in children (a surgery that removes the foreskin from the human penis) and to soothe itching around the rectum, anus (pruritus ani), or female genitalia (vulva).
It also relieves pain caused by oral sores and can numb the mouth and throat prior to any dental procedures (such as scaling or denture fixing).
It acts as an anaesthetic lubricant for catheterization, intubation, and other diagnostic procedures (such as proctoscopy, rectoscopy, cystoscopy, gastroscopy, bronchoscopy, esophagoscopy, etc.).
If you are managed with LIDOFIX GEL in your oral cavity, avoid oral foods or chewing gums for at least 60 minutes or until sensation comes back in your mouth. This is because you may experience trouble swallowing or accidentally bite your tongue or cheek muscles during this period.
Before using LIDOFIX GEL, inform your doctor if you have any liver, kidney, or heart problems. You must also inform your doctor if you have any infections or injuries at the site of application as a precaution.
LIDOFIX GEL can be used for pregnant and breastfeeding women if considered necessary. It is generally safe and well tolerated without any major side effects. However, if you experience any skin rash or irritation on the application site or feel drowsy, consult your doctor for advice.
Uses Of LIDOFIX GEL
It causes numbness and provides temporary relief from pain, itching, and discomfort associated with:
- skin abrasions, sun burns, insect bites, sore nipples
- shingles, bed sores, and cold sores
- haemorrhoids (piles), anal fissures, pruritus ani (itching of the anus)
- pruritus vulvae (itching of female genitalia)
- circumcision (a surgery that removes the foreskin from the human penis) in children
- oral sores and dental procedures (such as scaling or denture fixing)
- invasive procedures (such as the insertion of catheters or intubation tubes)
- diagnostic procedures (such as proctoscopy, rectoscopy, cystoscopy, gastroscopy, bronchoscopy, esophagoscopy, etc.)
How LIDOFIX GEL Works
LIDOFIX GEL is a local anaesthetic agent. It reduces pain sensation and causes numbness in body parts by blocking the flow of certain ions (sodium ions) through the nerves that cause pain sensation. As a result, it limits the transfer of pain signals from the peripheral part of the body (i.e., the face, hands, legs, abdomen, pelvis, genitals, or where the medicine has been applied) to the brain, which ultimately leads to loss of sensation.
How to use LIDOFIX GEL
LIDOFIX GEL should be used under proper medical supervision. It is administered by the physician in the region where anesthesia is required. However, it can also be self-administered by the patient if instructed by the doctor.
Take a small quantity of LIDOFIX GEL and apply it to the required areas. Avoid contact with LIDOFIX GEL with your eyes.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight, health condition, and sites where numbness is required in the body.
Side Effects Of LIDOFIX GEL
Rare
Consult your doctor immediately if you experience any of the following after using LIDOFIX GEL:
- signs of allergic reactions (such as skin rash, itching, swelling of the face, lips, throat, or tongue causing difficulty breathing or swallowing)
- dizziness or drowsiness, confusion, shortness of breath, ringing in the ears, blurred vision, slow heartbeat, feeling faint, nervousness, unusual sweating, trembling, or seizures
- signs of methemoglobinemia (such as pale, grey, or bluish discoloration of the skin, headache, abnormal or irregular heartbeat, dizziness, tiredness, etc.)
Warning & Precautions
Pregnancy
Consult your doctorLIDOFIX GEL can be used for pregnant women if considered necessary. However, consult your doctor for advice before using it.
Breastfeeding
Consult your doctorLIDOFIX GEL can be used for breastfeeding women if considered necessary. However, consult your doctor for advice before using it.
Driving and Using Machines
ContraindicatedDo not drive or operate any heavy tools or machines if your abilities are affected by LIDOFIX GEL.
Kidney
Use with CautionLIDOFIX GEL should be used with caution in patients with kidney diseases. Therefore, consult your doctor before applying.
Liver
Use with CautionLIDOFIX GEL should be used with caution in patients with liver diseases. Therefore, consult your doctor before applying.
Allergy
ContraindicatedTalk to your doctor before using LIDOFIX GEL if you are allergic to lignocaine or to any other amide local anaesthetics (Ex. bupivacaine).
Heart Disease
Use with CautionLIDOFIX GEL should be used with caution in patients with heart diseases (such as heart block or an abnormal or very slow heartbeat). Therefore, consult your doctor before applying.
Use In Pediatrics
Consult your doctorLIDOFIX GEL can be used in children and adolescents aged above 2 years after consulting your physician. It is not recommended for use in children aged below 2 years. Therefore, consult your doctor for advice.
Use In Geriatrics
Use with CautionLIDOFIX GEL should be used with caution with elderly patients. Therefore, consult your doctor for advice.
Others
Before using LIDOFIX GEL, inform your physician if you:
- have any open wounds, injuries, or infections at the site of application
- have porphyria (a rare inherited blood disorder)
- have epilepsy (fits)
- have or have a family history of malignant hyperthermia (a dangerous rise in body temperature)
Interactions
A. Drug-Drug interactions:
Before using LIDOFIX GEL, inform your doctor if you are taking any of the following medicines, such as:
- mexiletine, amiodarone (used to manage an uneven heartbeat)
- cimetidine (a medicine used to manage stomach ulcers)
- beta-blockers such as atenolol, propranolol, and bisoprolol (used to manage high blood pressure)
- nitrates (such as nitric oxide and nitroglycerin) are used to improve blood flow
- other local anaesthetic agents (such as bupivacaine, proparacaine, ropivacaine, mepivacaine, prilocaine, procaine, and tetracaine)
- antibiotics (used to manage bacterial infections) such as PABA, nitrofurantoin, dapsone, and sulfasalazine
- anticancer medicines (used to manage cancer) such as cyclophosphamide, ifosfamide, hydroxyurea, flutamide, and rasburicase
- antimalarial agents (used to manage malarial infection) Ex. chloroquine, primaquine, and quinine
- anti-epileptic agents (used to manage fits) Ex. phenytoin, sodium valproate, phenobarbital
- metoclopramide (a medicine used to manage nausea and vomiting)
Overdosage:
If you or anyone else has applied excessive LIDOFIX GEL, wipe off the excess with a paper towel or tissue paper. If your child or anyone else accidentally swallowed LIDOFIX GEL, contact your doctor immediately or visit a nearby hospital immediately, as it may lead to a severe decrease in low blood pressure.
Synopsis
| Drug | : | Lignocaine |
| Pharmacological Category | : | Amide Local Anaesthetics |
| Therapeutic Indication | : | Local anesthesia |
| Dosage Forms | : | Injection, Gel, Cream, Ointment, Jelly, Topical Solution, Spray, Oral solution, Plaster |
More Information
- Keep LIDOFIX GEL out of reach of children
- Store LIDOFIX GEL at room temperature
FAQs About LIDOFIX GEL
Q: How long will it take for LIDOFIX GEL to induce numbness?
A: It may take around 3-5 minutes for LIDOFIX GEL to create numbness. However, this period may vary from person-to-person based on the dose and amount of LIDOFIX GEL that is administered.
Q: How long do the effects of LIDOFIX GEL last in the body?
A: The effects of LIDOFIX GEL may last from 20–30 minutes up to 1 hour after application. However, the recovery period may vary from person-to-person based on the dose and amount of the LIDOFIX GEL applied.
Q: What is the use of LIDOFIX GEL?
A: LIDOFIX GEL is used to cause temporary numbness of body parts. It provides pain relief during skin abrasions, sunburns, insect bites, sore nipples, haemorrhoids (piles), anal fissures, bed sores, shingles or cold sores, circumcisions, and oral sores. It can also be used to soothe itching around the rectum, anus, or vulva, and it helps in the easy fix of catheters and intubation tubes. It also acts as an anaesthetic lubricant for various diagnostic procedures.
Q: How do I use LIDOFIX GEL?
A: LIDOFIX GEL should be used under proper medical supervision. It is usually administered by the physician prior to the surgical or diagnostic procedures. However, it may also be self-administered by the patient if instructed by the doctor for temporary pain relief. Take a small quantity of LIDOFIX GEL and apply it to the required areas. Avoid contact with LIDOFIX GEL with your eyes.
Q: Can LIDOFIX GEL be used with children?
A: LIDOFIX GEL can be used in children and adolescents aged above 2 years after consulting your physician. It is not recommended for use in children aged below 2 years. Therefore, consult your doctor for advice.
Q: Can you drink water after using LIDOFIX GEL?
A: Avoid eating foods or drinking water or other fluids after applying LIDOFIX GEL, as it may reduce its anaesthetic effects.
Q: How often can we use LIDOFIX GEL?
A: LIDOFIX GEL should be used as instructed by the doctor. Your doctor will decide the duration of therapy for you depending upon your age, body weight, health condition, and sites where numbness is required in the body.
Q: Can LIDOFIX GEL be used in infants?
A: LIDOFIX GEL is not recommended for use in children aged below 2 years. Therefore, consult your doctor for advice.
Q: Will LIDOFIX GEL cause sleepiness?
A: LIDOFIX GEL may cause sleepiness when used more than the recommended dosage. It may also happen if you apply this medicine more frequently over a shorter period of time. In such cases, consult your doctor for advice.
Q: What if I accidentally exposed LIDOFIX GEL to the eye?
A: Use lukewarm water to gently wash the outer surface of the eye in case of accidental contact with LIDOFIX GEL. If the discomfort in the eye persists, contact your doctor or visit a nearby hospital immediately.
Q: What do I do if I forget to take a dose of LIDOFIX GEL?
A: If you miss applying a dose of LIDOFIX GEL, apply it as soon as you remember. If it is time for the next dose, skip the missed dose and apply it the next time at regular times. Do not apply an excessive amount of LIDOFIX GEL to compensate for the missed dose.
References
1. KD. Tripathi. Drugs acting on peripheral (somatic) nervous system. Essentials of medical pharmacology. 8th Edition. 2019. Page – 392.
2. Natasha Beg, Thierry Vancaillie, Alan Hewitt, Julie Eggermont, Georgina Armstrong. NIH National Library of Medicine, National center for biotechnology information. Lignocaine gel in minimally invasive surgery - A pilot cohort, August 2010. [Accessed on 26th September 2022]. https://pubmed.ncbi.nlm.nih.gov/20716268/
3. Lidocaine Ointment. NIH. National Library of Medicine. Dailymed.com. [Revised in July 2022]. [Accessed on 26th September 2022]. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=88ca9cba-0c4a-482f-b502-ceefdb1bfbcd
4. Merckle GmbH. Teva.uk. [Revised in February 2022]. [Accessed on 26th September 2022]. https://products.tevauk.com/mediafile/id/52082.pdf
5. Aspen Pharmacare Australia Pty Ltd. Xylocaine 5% ointment. [Revised in February 2018]. [Accessed on 26th September 2022]. https://www.aspenpharma.com.au/wp-content/uploads/PICMI/CMI/CMI_XylocaineOintment.pdf
6. Pharmacy Retailing (NZ) Limited. Medsafe. [Revised in January 2018] Accessed on 26th September 2022]. https://www.medsafe.govt.nz/profs/Datasheet/x/Xylocainejelly.pdf
7. Aspen Pharmacare Australia. Xylocaine 2% Jelly. [Accessed on 26th September 2022]. https://www.xylocaine.com.au/jelly/
8. Aspen Pharmacare Australia. Xylocaine 5% Ointment. [Accessed on 26th September 2022]. https://www.xylocaine.com.au/ointment/




