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Introduction About LEXOL 100GM TABLET
LEXOL 100GM TABLET contains Labetalol which belongs to the group of medicines called Alpha, Beta Adrenergic Antagonists. It is used to manage hypertension and angina. It can also be used to control hypertension among pregnant women.
Hypertension (also known as high blood pressure) is a medical condition in which the force of the blood exerted against the walls of the artery remains very high and as a result it may lead to severe damage to the blood vessels supplying vital organs, such as heart, kidney or brain. If left unmanageed, it may cause serious complications such as heart attack, heart failure, stroke or even blindness.
Angina pectoris is a type of chest pain caused due to an inadequate supply of oxygen to the heart muscle. Symptoms include severe chest pain, tightness or heaviness with dizziness, fatigue, sweating, shortness of breath and fast heart rate.
Before taking LEXOL 100GM TABLET inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have any other types of anginas (such as Prinzmetal angina), psoriasis, diabetes or if you are scheduled for any surgery (including cataract surgery) in the upcoming days as a precaution.
LEXOL 100GM TABLET is not recommended for use in patients with asthma, hypotension (low blood pressure) or shock. It is also not suitable for use in patients with heart block, history of heart attack or heart failure.
LEXOL 100GM TABLET should be used in pregnant or breastfeeding women only if considered necessary by the physician. Therefore, consult your doctor before taking it.
The most common side effects of taking LEXOL 100GM TABLET are difficulty in passing urine, problems in erection or ejaculation, dizziness and tingling sensation in the scalp. Consult your doctor if any of these side effect troubles you.
Uses Of LEXOL 100GM TABLET
- Manage hypertension (including high blood pressure during pregnancy)
- Manage angina (chest pain)
How LEXOL 100GM TABLET Works
LEXOL 100GM TABLET is an alpha, beta-blocker. It works by blocking the actions of certain chemical messengers (such as adrenaline and noradrenaline) in our body that controls the functions of the heart, brain, kidneys and lungs. This action relaxes the blood vessels supplying the heart and improves blood flow and oxygen supply within them which helps in reducing chest pain (angina). It also reduces the strain on the heart and helps the heart to pump blood more efficiently with less pressure.
How to use LEXOL 100GM TABLET
Take LEXOL 100GM TABLET as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Try to take LEXOL 100GM TABLET at the same time each day. It is preferable to be taken after meals.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. Do not stop taking LEXOL 100GM TABLET unless advised by your doctor.
Side Effects Of LEXOL 100GM TABLET
Common
- difficulty in passing urine
- problems in erections or ejaculation
- dizziness
- fever, flu-like symptoms
- tingling sensation in the scalp
- raised liver enzymes in the blood
- positive for anti-nuclear antibody blood test
Rare
- very slow heartbeat
Stop taking LEXOL 100GM TABLET and contact your doctor immediately if you experience any of the following side effects such as:
- signs of allergic reactions (such as skin rash, swelling of the face, lips, mouth or throat which can lead to difficulty in breathing or swallowing)
- difficulty in breathing, swollen ankles, abnormal heart rate
- severe skin reactions (such as skin rash with itching and redness, blistering and peeling of skin, skin swelling and inflammation of mucous membrane, joint pain with fever)
- signs of liver problems (yellowing of skin and whites of the eye, dark urine and pale stools)
- lung inflammation causing cough and breathing problems
How To Manage Side Effects
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Warning & Precautions
Pregnancy
LEXOL 100GM TABLET should be used during pregnancy only if considered necessary by the physician. Therefore, consult your doctor before taking it.
Breastfeeding
LEXOL 100GM TABLET may excrete in breast milk. Therefore, it should be used in breastfeeding women only if considered necessary by the physician. Consult your doctor for advice before taking it.
Driving and Using Machines
Do not drive or operate any heavy tools or machines if you feel dizzy or tired after taking LEXOL 100GM TABLET.
Alcohol
Avoid consumption of alcohol while taking LEXOL 100GM TABLET as it might make you feel dizzier and drowsier.
Kidney
LEXOL 100GM TABLET should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.
Liver
LEXOL 100GM TABLET should be used with caution in patients with liver problems. Therefore, consult your doctor before taking it.
Allergy
Do not take LEXOL 100GM TABLET if you are allergic to labetalol.
Lungs
LEXOL 100GM TABLET is not recommended to use in patients with a history of asthma, wheezing or any lung diseases. Therefore, consult your doctor before taking it.
Heart Disease
LEXOL 100GM TABLET is not recommended for use in patients with heart problems (such as slow heart rate, heart failure, heart block or heart rhythm disorder). Therefore, consult your doctor before taking it.
Others
LEXOL 100GM TABLET is not recommended for use if you:
- have low blood pressure
- have cardiogenic shock (heart cannot pump blood suddenly)
- have severe problems in blood circulation
- have an increased acidity of the blood (metabolic acidosis)
- are on a strict fasting diet or not eating properly
- suffer from other forms of angina (Prinzmetal’s angina)
- have phaeochromocytoma (tumors of adrenal gland)
Before taking LEXOL 100GM TABLET, inform your doctor if you:
- have poor blood circulation (Ex. Raynaud’s disease)
- have ever had psoriasis (red scaly patches on the skin)
- are planning for any surgery (including cataract surgery)
- have diabetes
- are going for any urine test
Use in pediatrics:
LEXOL 100GM TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.
Use in geriatrics:
LEXOL 100GM TABLET should be used with caution in elderly patients (aged above 65 years). Therefore, consult your doctor before taking it.
Interactions
A. Drug-Drug interactions:
Before taking LEXOL 100GM TABLET, inform your doctor if you are taking any of the following medicines such as:
- other medicines used in the management of hypertension and other heart problems (Ex. nifedipine, nisoldipine, nicardipine, isradipine, lacidipine, verapamil, diltiazem, hydralazine, clonidine, enalapril, lisinopril, ramipril, disopyramide, quinidine, amiodarone, isoprenaline, dobutamine, propafenone and digoxin)
- other beta-blockers (used to manage heart problems) Ex. atenolol, propranolol
- medicines used to manage diabetes (Ex. insulin, metformin)
- adrenaline (a medicine that can stimulate the heart)
- medicine used to relieve pain and inflammation (Ex. ibuprofen, indomethacin, hydrocortisone)
- medicines used to manage migraine headaches (Ex. ergotamine, dihydroergotamine or rizatriptan)
- medicine used in the management of mental illness (Ex. chlorpromazine, thioridazine, haloperidol)
- cimetidine, aluminium hydroxide gel (medicine used for stomach problems)
- barbiturates (medicine used to reduce anxiety and to induce sleep) Ex. phenobarbitone, pentobarbitone
- medicines used to manage depression (Ex. isocarboxazid, phenelzine, Selegiline, fluvoxamine and Tranylcypromine, amitriptyline)
- medicines used to manage malaria (Ex. mefloquine or quinine)
- alprostadil (a medicine used to manage impotence)
- moxisylyte (a medicine used to manage Raynaud’s disease)
- aldesleukin (a medicine used to manage secondary cancer of the kidney)
- contraceptive pills (birth control pills) Ex. ethinylestradiol
Overdosage:
If you or anyone else accidentally took more LEXOL 100GM TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include slow heartbeat, low blood pressure, breathing difficulties and decrease in blood sugar which can cause sweating and confusion.
Synopsis
| Drug | : | Labetalol |
| Pharmacological Category | : | Alpha, Beta Adrenergic Antagonists |
| Therapeutic Indication | : | Hypertension, Angina |
| Dosage Forms | : | Tablet, Capsule, Injection |
More Information
- Keep LEXOL 100GM TABLET out of reach of children
- Store LEXOL 100GM TABLET at room temperature
FAQs About LEXOL 100GM TABLET
Can LEXOL 100GM TABLET used in asthmatic patients?
No, LEXOL 100GM TABLET cannot be used in patients suffering from asthma. This is because using it can cause breathing problems, which may trigger an asthma attack. Always inform your doctor if you have or ever had asthma or any kind of difficulty breathing difficulty, before starting management with LEXOL 100GM TABLET.
Does LEXOL 100GM TABLET make you feel sleepy?
LEXOL 100GM TABLET may occasionally can cause dizziness or tiredness while taking it. Don't drive, use machinery or perform any activities that require alertness. If this occurs to you, consult your doctor for opinion.
Should we take LEXOL 100GM TABLET before or after food?
LEXOL 100GM TABLET should preferably be taken with meals. It should be swallowed with a drink of water.
When can I expect relief in my symptoms after taking LEXOL 100GM TABLET?
LEXOL 100GM TABLET usually starts working within a few hours of taking it. However, to notice considerable changes in the symptoms of high blood pressure or heart conditions, it may take a week. You will not be able to notice any difference, but that does not mean it is not working. However, keep taking LEXOL 100GM TABLET as prescribed by your doctor to get its full benefits.
What are the uses of LEXOL 100GM TABLET?
LEXOL 100GM TABLET It is used to manage hypertension and angina. It can also be used to manage high blood pressure during pregnancy.
What type of a medicine is LEXOL 100GM TABLET?
LEXOL 100GM TABLET is an alpha, beta-blocker. It works by blocking the actions of certain chemical messengers (such as adrenaline and noradrenaline) in our body that controls the functions of the heart, brain, kidneys and lungs. This action relaxes the blood vessels supplying the heart and improves blood flow and oxygen supply within them which helps in reducing chest pain (angina). It also reduces the strain on the heart and helps the heart to pump blood more efficiently with less pressure.
What happens when I stop taking LEXOL 100GM TABLET?
Do not stop taking LEXOL 100GM TABLET without consulting your doctor as your symptoms may re-appear once again. Make sure to take LEXOL 100GM TABLET for the stipulated duration recommended by your doctor to achieve maximum results.
What is the best time to take LEXOL 100GM TABLET?
LEXOL 100GM TABLET is preferably taken with meals. Your doctor will decide the best time for you to take LEXOL 100GM TABLET based on your age, body weight and disease condition.
What to do if I forgot to take a dose of LEXOL 100GM TABLET?
If you forgot to take a dose of LEXOL 100GM TABLET, take it as soon as you remember. However, if it is time for the next dose of LEXOL 100GM TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of LEXOL 100GM TABLET to compensate the missed ones.
What precautions should be followed while taking LEXOL 100GM TABLET?
Before taking LEXOL 100GM TABLET inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have any other types of anginas (such as Prinzmetal angina), psoriasis, diabetes or if you are scheduled for any surgery (including cataract surgery) in the upcoming days as a precaution. LEXOL 100GM TABLET is not recommended for use in patients with asthma, hypotension (low blood pressure) or shock. It is also not suitable for use in patients with heart block, history of heart attack or heart failure. Do not take LEXOL 100GM TABLET without consulting your doctor if you are pregnant or breastfeeding. Regularly visit your doctor and take all the necessary blood test recommended by your doctor without fail.
Can I consume alcohol while taking LEXOL 100GM TABLET?
Avoid consumption of alcohol while taking LEXOL 100GM TABLET as it might make you feel dizzier and drowsier.
What happens if I accidentally take more LEXOL 100GM TABLET?
If you or anyone else accidentally took more LEXOL 100GM TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include slow heartbeat, low blood pressure, breathing difficulties and decrease in blood sugar levels causing sweating and confusion.
Can I take LEXOL 100GM TABLET daily?
Take LEXOL 100GM TABLET as advised by your physician. Your doctor will evaluate your health condition and suggests whether can you take LEXOL 100GM TABLET every day or not.
Is LEXOL 100GM TABLET safe to use in diabetic patients?
LEXOL 100GM TABLET may alter the blood sugar levels in your body. Therefore, it is necessary to inform your doctor if you have diabetes before taking LEXOL 100GM TABLET as a precaution. Your doctor will closely monitor you blood sugar levels to avoid the risk of side effects.
What are the side effects of LEXOL 100GM TABLET?
The most common side effects of taking LEXOL 100GM TABLET are difficulty in passing urine, problems in erection or ejaculation, dizziness and tingling sensation in the scalp. Consult your doctor if any of these side effect troubles you.
Can I stop taking LEXOL 100GM TABLET once my symptoms subside?
No. Do not stop taking LEXOL 100GM TABLET without consulting your doctor as it may make your symptoms reappear. Therefore, take LEXOL 100GM TABLET as advised by your doctor for the stipulated duration.
Can LEXOL 100GM TABLET be taken during pregnancy?
LEXOL 100GM TABLET should be used during pregnancy only if considered necessary by the physician. Therefore, consult your doctor before taking it.
Is LEXOL 100GM TABLET safe to use in kidney disease?
LEXOL 100GM TABLET should be used with caution in patients with kidney problems. Your doctor will access your health condition and suggest a suitable dose for you.
Can the use of LEXOL 100GM TABLET affect the liver?
Yes. LEXOL 100GM TABLET may affect the way your liver work. It can elevate the levels of certain liver enzymes in your body. Therefore, it should be used with caution in patients with liver problems. Consult your doctor before taking it.
Can the use of LEXOL 100GM TABLET affect my sexual life?
LEXOL 100GM TABLET may cause problems in erection and ejaculation in some individuals. Consult your doctor if it troubles you.
References
1. KD. Tripathi. Adrenergic drugs and drugs acting on glaucoma. Essentials of medical pharmacology. 7th Edition. 2019. Page –151.
2. Louise M. Webster, Jenny E. Myers, Catherine Nelson-Piercy, Kate Harding, J. Kennedy Cruickshank, Ingrid Watt-Coote, Asma Khalil, Cornelia Wiesender, Paul T. Seed and Lucy C. Chappell. Labetalol Versus Nifedipine as Antihypertensive Treatment for Chronic Hypertension in Pregnancy. Journal of Hypertension. September 2017. [Accessed on 9th November 2022] https://www.ahajournals.org/doi/10.1161/hypertensionaha.117.09972
3. Prof Thomas Easterling, MD, Prof Shuchita Mundle, MD, Hillary Bracken, PhD, Seema Parvekar, MD, Sulabha Mool, DGO, Prof Laura A Magee, MD, Prof Peter von Dadelszen, Dphil Tara Shochet, PhD, Prof Beverly Winikoff, MD. Oral antihypertensive regimens (nifedipine retard, labetalol and methyldopa) for management of severe hypertension in pregnancy: an open label, randomized controlled trial. The Lancet. September 2019. [Accessed on 9th November 2022] https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)31282-6/fulltext
4. Mylan Laboratories Limited. Electronic Medicines Compendium (EMC). [Revised in January 2022]. [Accessed on 9th November 2022] https://www.medicines.org.uk/emc/files/pil.2648.pdf
Useful Diagnostic Tests
- Kidney Function Test
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