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Introduction About LESURIDE MPS TABLET
LESURIDE MPS TABLET contains Levosulpiride, which belongs to the group of medicines called Prokinetic agents. It is used to manage nausea, vomiting, and indigestion. It can also be used to manage diabetic gastroparesis.
Diabetic gastroparesis is a stomach condition caused by poorly controlled diabetes. It manages the stomach muscles from emptying their digested contents into the intestines. This creates a feeling of fullness even after eating only a little amount of food, along with nausea and a lack of appetite.
Before taking LESURIDE MPS TABLET, inform your doctor if you have any kidney or heart problems. You must also inform your doctor if you have epilepsy, mania, or any other mental illness as a precaution.
LESURIDE MPS TABLET is not recommended for use in patients having bleeding or any blockage or tear in the gut. It is also not suitable for use in patients having cancer or tumours in the body. Do not take LESURIDE MPS TABLET without consulting your doctor if you are pregnant or breastfeeding.
The most common side effects of taking LESURIDE MPS TABLET are headache, drowsiness, tiredness, breast enlargement and discharge, and a decrease in sex drive. Consult your doctor if any of these side effects bother you.
Uses Of LESURIDE MPS TABLET
It is used to manage:
- nausea and vomiting
- indigestion
- diabetic gastroparesis (causing sensation of fullness or lack of appetite)
How LESURIDE MPS TABLET Works
LESURIDE MPS TABLET is a prokinetic medicine with anti-emetic and anti-dyspeptic properties. It acts by blocking the actions of certain chemical messengers (dopamine) in the brain that control the movement of stomach muscles. This action improves muscle movement in the stomach (gastric motility) and reduces the unpleasant symptoms of the GI tract (such as nausea, vomiting, indigestion, sensation of fullness, and lack of appetite).
How to use LESURIDE MPS TABLET
Take LESURIDE MPS TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight, and disease condition. Do not stop taking LESURIDE MPS TABLET unless your doctor advises you to stop.
Side Effects Of LESURIDE MPS TABLET
Common
- headache
- drowsiness, tiredness
- weight gain
- lack of sleep
- increased salivation, tremor
- breast enlargement and discharge
- decrease in sex drive, problems in erection
Rare
Stop taking LESURIDE MPS TABLET and inform your doctor immediately if you experience any of the following side effects, such as:
- signs of neuroleptic malignant syndrome (such as high fever, rigid muscles, mood swings, fast or irregular heartbeat, changes in blood pressure, increased sweating)
- feeling dizzy or faint while standing up
- severe skin reactions (such as redness, blistering, peeling of skin, and bleeding in the lips, eyes, mouth, nose, and genitals with fever)
- chest pain, fast or irregular heartbeat, difficulty breathing, feeling faint
How To Manage Side Effects
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling drowsy. Do not consume excessive alcohol, as it could aggravate your drowsiness. Consult your doctor if your sleepiness worsens.
Headache
Rest and relax. Keep yourself hydrated by drinking plenty of fluids, such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Warning & Precautions
Pregnancy
ContraindicatedLESURIDE MPS TABLET is not recommended for use in pregnant women. Therefore, consult your doctor before taking it.
Breastfeeding
ContraindicatedLESURIDE MPS TABLET is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.
Driving and Using Machines
Use with CautionDo not drive or operate any heavy tools or machines if you feel drowsy after taking LESURIDE MPS TABLET.
Alcohol
Use with CautionAvoid consumption of alcohol while taking LESURIDE MPS TABLET, as it could make you feel drowsier.
Kidney
Use with CautionLESURIDE MPS TABLET should be used with caution in patients with kidney problems. Therefore, consult with your doctor before taking it.
Allergy
ContraindicatedDo not take LESURIDE MPS TABLET if you are allergic to Levosulpiride.
Heart Disease
Use with CautionLESURIDE MPS TABLET should be used with caution in patients with heart problems (such as cardiac insufficiency, prolong QT interval). Therefore, consult with your doctor before taking it.
Use In Pediatrics
Consult your doctorLESURIDE MPS TABLET should be used in children and adolescents (aged 14 years or above) only if prescribed by the physician. It is not recommended for use in children aged below 14 years due to a lack of safety data. Therefore, consult your doctor for advice.
Use In Geriatrics
Use with CautionLESURIDE MPS TABLET should be used with caution in elderly patients. Therefore, consult your doctor before taking it.
Others
LESURIDE MPS TABLET is not recommended for use if you:
- have pheochromocytoma (tumours of the adrenal gland)
- have epilepsy (fits)
- have prolactinoma (a non-cancerous tumour of the pituitary gland)
- have breast cancer
- have mania (elevated mood)
- have manic depression (alternative episodes of excitement and sadness)
- have bloody stools or bleeding in the gut
- have blockage or tear in the intestines
Before taking LESURIDE MPS TABLET, inform your doctor if you:
- have or had a previous history of stroke or problems in blood circulation
Interactions
A. Drug- Drug Interactions:
Before taking LESURIDE MPS TABLET, inform your doctor if you are taking any of the following medicines, such as:
- levodopa, ropinirole (medicines used to manage Parkinsonism)
- medicines used to manage high blood pressure (such as propranolol, atenolol, amlodipine, diltiazem, clonidine, ramipril, and azilsartan)
- medicines used to manage irregular heartbeats (such as digitalis, quinidine, disopyramide, amiodarone, and sotalol)
- medicines that can remove potassium from the body, such as diuretics (Ex. furosemide, hydrochlorothiazide)
- amphotericin B (a medicine used to manage fungal infection)
- laxatives (used to manage constipation) Ex. lactulose, calcium dobesilate
- corticosteroids (used to manage pain and inflammation) Ex. prednisolone, dexamethasone, hydrocortisone
- tetracosectides (a diagnostic agent used for screening problems of the adrenal gland)
- medicines used to manage severe tics (such as pimozide)
- medicine used to manage mental illness or depression (such as haloperidol, lithium, imipramine, thioridazine, and sulpiride)
- methadone (a medicine used to manage drug addiction)
- other medicines used to manage stomach disorders (such as cisapride, aluminium hydroxide, and sucralfate)
- erythromycin (a medicine used to manage bacterial infections)
- halofantrine (a medicine used to manage malaria)
- pentamidine (a medicine used to manage pneumonia)
- medicines used to manage anxiety (such as diazepam, clonazepam, pentobarbital, and phenobarbital)
- narcotic analgesics (used for pain relief) Ex. morphine, fentanyl, pethidine
- medicines used to manage allergic reactions (Ex. cetirizine, levocetirizine)
Overdosage:
If you or anyone else accidentally took more LESURIDE MPS TABLET, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Levosulpiride |
| Pharmacological Category | : | Dopamine (D2) receptor antagonists |
| Therapeutic Indication | : | Indigestion, Nausea, Vomiting, Diabetic gastroparesis |
| Dosage Forms | : | Tablet, Capsule, Injection |
More Information
Storage
- Keep LESURIDE MPS TABLET out of the sight and reach of children
- Store LESURIDE MPS TABLET at room temperature
FAQs About LESURIDE MPS TABLET
Q: What is LESURIDE MPS TABLET used for?
A: LESURIDE MPS TABLET is used to manage nausea, vomiting, and indigestion. It can also be used to manage diabetic gastroparesis.
Q: How and when to take LESURIDE MPS TABLET?
A: Take LESURIDE MPS TABLET as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight, and disease condition.
Q: How long should I take LESURIDE MPS TABLET?
A: You need to take LESURIDE MPS TABLET for the stipulated duration prescribed by your doctor. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight, and disease condition.
Q: What to do if I forgot to take a dose of LESURIDE MPS TABLET?
A: If you forgot to take a dose of LESURIDE MPS TABLET, take it as soon as you remember. However, if it is time for the next dose of LESURIDE MPS TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of LESURIDE MPS TABLET to compensate for the missed ones.
Q: What are the most common side effects of taking LESURIDE MPS TABLET?
A: The most common side effects of taking LESURIDE MPS TABLET are headache, drowsiness, tiredness, breast enlargement and discharge, and a decrease in sex drive. Consult your doctor if any of these side effects bother you.
Q: Can I stop taking LESURIDE MPS TABLET without consulting your doctor?
A: No. You should not stop taking LESURIDE MPS TABLET without consulting your doctor because it may lead to reversal of symptoms. If you feel better after using LESURIDE MPS TABLET, consult your doctor for advice.
Q: Will taking a higher dose of LESURIDE MPS TABLET be more effective?
A: No, taking a higher dose of LESURIDE MPS TABLET will not be effective; rather, it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.
Q: What precautions do I need to follow while taking LESURIDE MPS TABLET?
A: Before taking LESURIDE MPS TABLET, inform your doctor if you have any kidney or heart problems. You must also inform your doctor if you have epilepsy, mania, or any other mental illness as a precaution. LESURIDE MPS TABLET is not recommended for use in patients having bleeding or any blockage or tear in the gut. It is also not suitable for use in patients having cancer or tumours in the body. Do not take LESURIDE MPS TABLET without consulting your doctor if you are pregnant or breastfeeding.
Q: Can I take medication for high blood pressure along with LESURIDE MPS TABLET?
A: It is not advisable to take medicines to control blood pressure along with LESURIDE MPS TABLET without consulting your doctor, as they may further reduce your blood pressure and make you feel dizzy.
Q: Can LESURIDE MPS TABLET be used in pregnant women?
A: LESURIDE MPS TABLET is not recommended for use in pregnant women. Therefore, consult your doctor before taking it.
Q: Can LESURIDE MPS TABLET make me feel drowsy?
A: Yes. Drowsiness is one of the common side effects of taking LESURIDE MPS TABLET. Avoid driving or operating any tools or machines completely while you are feeling drowsy. Do not consume excessive alcohol, as it could aggravate your drowsiness. Consult your doctor if your sleepiness worsens.
Q: Can the use of LESURIDE MPS TABLET affect my sexual life?
A: LESURIDE MPS TABLET may cause a decrease in sex drive and problems in erection in some individuals, although not everybody gets them. These side effects are usually temporary and disappear once the therapy is stopped. However, consult your doctor if it bothers you.
References
1. Laurence Brunton, John Lazo, Keith Parker. Drugs Affecting Gastrointestinal Function. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. Eleventh Edition. 2005. Page – 986.
2. Chi-Wook Song, Hoon-Jae Chun, Chang-Duck Kim, Ho-Sang Ryu, Jae-Gol Choe, Jin-Hai Hyun. Effects of Levosulpiride in Patients with Functional Dyspepsia Accompanied by Delayed Gastric Emptying. NIH National Library of Medicine, National Centre for Biotechnology Information. PMC. PubMed Central. February 1998. [Accessed on 23rd August 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531935/
3. Torrent Pharmaceuticals Ltd. Levazo 25. [Accessed on 23rd August 2024] https://www.torrentian.com/pisheet/Upload/PI_Sheet/1398.pdf
4. Torrent Pharmaceuticals Ltd., Levazo SR 75. [Accessed on 23rd August 2024] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2483.pdf
5. Central Drugs Standard Control Organization. Levosulpiride Tablet (25 mg). May 2007. Levosulpiride 75/150/200 mg (add strength). December 2014. [Accessed on 23rd August 2024] https://cdscoonline.gov.in/CDSCO/Drugs
Useful Diagnostic Tests
- Complete Blood Count (CBC)/ Hemogram
- Monsoon Gastro Infection Panel
- Gastro / Gut Health Panel
- Healthy Midlife Checkup
- Men Health Checkup - Advanced
- Complete Women Checkup
- Full Body Checkup - Gold
- Full Body Checkup – Silver
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