Sun Pharmaceutical Industries Ltd

Krimson 35mg Tablet 21'S

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Introduction About KRIMSON 35MG TABLET

Krimson 35 Tablet is a combination of two hormonal medicines used to manage symptoms of polycystic ovary syndrome (PCOS), such as excessive hair growth (hirsutism), acne, and irregular periods. It also works as a contraceptive; hence, avoid using any other contraceptive pill.

Krimson 35 Tablet can be taken with or without food. Take it at the same time every day, as it will help you remember to take it. The dose and duration will depend on what you are being managed for, but you should always complete a full course of this medicine as prescribed by your doctor.

Do not continue with the medicine and consult with the doctor if your periods do not start within a week of the management. Your doctor should also know about all other medicines you are taking, as many of these may make this medicine less effective or change the way it works. Avoid the use of medicine if you are pregnant or breastfeeding.

The most common side effects of this medicine include nausea, stomach pain, headache, weight gain, and breast pain. If these bother you or appear serious, let your doctor know. There may be ways of reducing them. Consult your doctor if you frequently experience spotting or brown discharge in the middle of the cycle. You must also consult your doctor if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, or vision changes.

Uses Of KRIMSON 35MG TABLET

  • Management of Polycystic ovarian syndrome (PCOS)

Benefits of KRIMSON 35MG TABLET

  • Women with polycystic ovarian syndrome (PCOS) have high levels of male hormones called androgens, which are responsible for irregular menstrual cycles (periods), excessive hair growth, and acne.
  • Krimson 35 Tablet is a combination medicine that helps in regulating the production of these androgens as well as periods in females.
  • This also helps in managing excessive hair growth (hirsutism) and acne effectively.
  • Take it as prescribed by the doctor. Do not skip any doses, and follow your doctor’s instructions carefully to get maximum benefit.

How KRIMSON 35MG TABLET Works

  • Krimson 35 Tablet is a combination of two hormonal medicines, cyproterone and ethinyl estradiol, which manages PCOS symptoms such as acne, excessive hair growth (hirsutism), and irregular periods.
  • Cyproterone works by blocking the overproduction of androgens (male hormones) in the ovaries, thereby reducing unwanted hair growth and acne.
  • Ethinyl estradiol enhances the effect of cyproterone by reducing the amount of androgens in the blood. Together, they also regularize the menstrual cycle in PCOS.

How to use KRIMSON 35MG TABLET

Krimson 35 Tablet contains Cyproterone Acetate and Ethinyl Estradiol. It should be used exactly as prescribed by a healthcare professional.

How to Take Krimson 35 Tablet

  • Swallow the tablet whole with a glass of water.
  • The tablet can be taken with or without food.
  • Take the tablet at the same time each day to maintain consistent hormone levels.
  • Follow the dosing schedule provided by your healthcare professional carefully.
  • Do not alter the dose or stop the medicine without medical advice.

Starting the Management

  • It is usually started according to the schedule advised by the prescribing healthcare professional.
  • Follow the instructions on the package and prescription label carefully.
  • If switching from another hormonal medicine, follow your doctor's guidance regarding the start date.

During Management

  • Take one tablet daily according to the prescribed regimen.
  • Consistency is important for maintaining the intended hormonal effect.
  • Keep track of tablet intake using a calendar or medication reminder if needed.

General Administration Tips

  • Attend regular follow-up appointments as recommended.
  • Inform your healthcare professional about any new medications started during therapy.
  • Keep the tablets in their original packaging until use.
  • Store according to the package instructions.

What if I forgot to take KRIMSON 35MG TABLET

  • Follow the instructions provided in the package leaflet or by your healthcare professional.
  • Missing doses may affect the effectiveness of the medicine
  • Do not take extra tablets unless specifically instructed by a healthcare professional.

Side Effects Of KRIMSON 35MG TABLET

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Krimson

  • Nausea
  • Stomach pain
  • Headache
  • Weight gain
  • Breast pain
  • Mood changes

Warning & Precautions

Pregnancy

Contraindicated

Krimson 35 Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breastfeeding

Contraindicated

Krimson 35 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving and Using Machines

Use with Caution

Krimson 35 Tablet does not usually affect your ability to drive.

Alcohol

Use with Caution

Alcohol should be used with caution while taking Krimson 35 Tablet.

Kidney

Consult your doctor

There is limited data available on the use of Krimson 35 Tablet in patients with kidney disease. Please consult your doctor.

Liver

Consult your doctor

There is limited data available on the use of Krimson 35 Tablet in patients with liver disease.

Allergy

Contraindicated

Do not use Krimson 35 Tablet if you have a known allergy to Cyproterone Acetate, Ethinyl Estradiol, or any other ingredient in the formulation.

Use In Pediatrics

Consult your doctor

Krimson 35 Tablet is generally intended for use only after the onset of menstruation (menarche).  Its use in pre-pubertal children is not recommended. In adolescents, the medicine should be used only under the supervision of a qualified healthcare professional.

Use In Geriatrics

Contraindicated

Krimson 35 Tablet is generally not recommended for use in postmenopausal women. Safety and efficacy data in elderly patients are limited. Older adults may have a higher likelihood of underlying medical conditions that require careful assessment before use.  Inform the healthcare professional about any history of cardiovascular disease, liver disorders, kidney problems, or other chronic health conditions. Regular medical review may be recommended if use is considered necessary.

Drug - Drug interaction

Enzyme-Inducing Medicines

These medicines may reduce the effectiveness of Krimson 35 Tablet by increasing hormone metabolism:

  • Rifampicin
  • Rifabutin
  • Carbamazepine
  • Phenytoin
  • Phenobarbital
  • Primidone
  • Oxcarbazepine
  • Topiramate
  • Felbamate

Antiretroviral Medicines

Certain HIV medicines may alter hormone concentrations:

  • Ritonavir
  • Nevirapine
  • Efavirenz
  • Lopinavir
  • Darunavir

Antifungal Medicines

Some antifungal agents may increase hormone exposure:

  • Ketoconazole
  • Itraconazole
  • Fluconazole
  • Voriconazole

Antibiotics

Certain antibiotics may influence hormone metabolism or absorption:

  • Rifampicin
  • Rifabutin

Anticoagulants

Hormonal medicines may affect the action of blood-thinning medications:

  • Warfarin
  • Acenocoumarol

Antidiabetic Medicines

Blood glucose control may require monitoring:

  • Metformin
  • Glimepiride
  • Gliclazide
  • Insulin
  • Sitagliptin

Immunosuppressants

Krimson 35 Tablet may affect blood levels of:

  • Cyclosporine
  • Tacrolimus

Antiepileptic Medicines

May reduce hormonal effectiveness:

  • Lamotrigine
  • Carbamazepine
  • Phenytoin
  • Topiramate
  • Phenobarbital

Corticosteroids

Hormonal components may alter corticosteroid effects:

  • Prednisolone
  • Dexamethasone
  • Methylprednisolone

Herbal Products

Certain herbal supplements may reduce effectiveness:

  • St. John's Wort (Hypericum perforatum)

Thyroid Hormone Therapy

Monitoring may be required in patients taking:

  • Levothyroxine

Medicines Affecting Potassium Levels

Cyproterone acetate may require caution when used with medicines that increase potassium levels:

  • Spironolactone
  • Eplerenone
  • Amiloride
  • ACE inhibitors (e.g., Enalapril, Ramipril)
  • ARBs (e.g., Losartan, Telmisartan)

More Information

1. Understanding the Anti-Androgen Component in Krimson 35 Tablet

One of the unique features of Krimson 35 Tablet is the presence of cyproterone acetate, an anti-androgenic hormone. Androgens are hormones naturally present in both men and women, but elevated androgen activity in women can contribute to certain hormone-related conditions. Cyproterone acetate helps reduce the effects of these hormones by blocking androgen receptors and reducing androgen production.

Why This Is Important

  • Provides both hormonal regulation and anti-androgen activity in a single formulation.
  • Targets hormone-related concerns associated with excess androgen influence.
  • Offers a different approach compared to conventional estrogen-only hormonal therapies.
  • Helps maintain hormonal balance through multiple complementary mechanisms.

2. Importance of Regular Monitoring During Long-Term Hormonal Therapy

Hormonal medicines often require periodic medical review to ensure continued suitability and effectiveness. Regular follow-up visits allow healthcare professionals to assess overall health, review medication history, and discuss any changes that may affect therapy.

What May Be Reviewed During Follow-Up

  • Blood pressure measurements.
  • Weight and general health assessment.
  • Review of current medications and supplements.
  • Discussion of menstrual cycle patterns and overall wellbeing.
  • Evaluation of adherence to the prescribed regimen.

Patient Benefit

Maintaining scheduled follow-up appointments can help optimize therapy management and ensure that any concerns are addressed promptly.

3. Lifestyle Factors That Can Support Hormonal Health

While medication plays an important role, lifestyle habits can also contribute to overall hormonal wellbeing. Patients taking Krimson 35 Tablet may benefit from adopting healthy daily routines that support general health.

Practical Recommendations

  • Maintain a balanced diet rich in fruits, vegetables, whole grains, and lean proteins.
  • Engage in regular physical activity appropriate for your health status.
  • Aim for adequate sleep and consistent sleep schedules.
  • Manage stress through relaxation techniques, mindfulness, or other healthy coping strategies.
  • Keep a record of menstrual cycles and health changes to discuss during medical consultations.

Patient Education Insight

Many individuals find that combining prescribed hormonal therapy with healthy lifestyle habits helps them stay engaged with their long-term healthcare plan and facilitates more productive discussions during follow-up visits.

FAQs About KRIMSON 35MG TABLET

Q: What is Krimson 35 Tablet?

A: Krimson 35 Tablet is a combination of two hormonal medicines: cyproterone and ethinyl estradiol. It manages PCOS symptoms such as acne, excessive hair growth (hirsutism), and irregular periods. Cyproterone works by blocking the overproduction of androgens (male hormones) in the ovaries, thereby reducing unwanted hair growth and acne. Ethinyl estradiol enhances the effect of cyproterone by reducing the amount of androgens in the blood circulation.

Q: How and in what dose should I take Krimson 35 Tablet?

A: Krimson 35 Tablet has to be started on day 1 or 2 of your menstrual cycle. Take it for the duration advised by your doctor. However, it is recommended to take it at the same time each day. This will ensure consistent levels of medicine in your body.

Q: What if I miss a dose of Krimson 35 Tablet?

A: If you miss a dose, you should take it as soon as possible. If the dose was missed by more than 12 hours, you should not take the missed dose and simply continue the usual dosing schedule. However, to stop pregnancy, another non-hormonal birth control method (like condoms) should be used during this cycle. Frequent missing of doses may also cause unexpected vaginal bleeding or spotting (blood stain). If it lasts long, consult your doctor.

Q: What if I vomit after few hours of taking Krimson 35 Tablet?

A: If vomiting occurs within 3-4 hours of taking the tablet, you must repeat the dose.

Q: Does Krimson 35 Tablet also work as a contraceptive?

A: Yes, if taken as advised, Krimson 35 Tablet also acts as a contraceptive. Discontinue using any other birth control pill while taking Krimson 35 Tablet.

Q: What are the common side effects of taking Krimson 35 Tablet?

A: The most common side effects associated with Krimson 35 Tablet are nausea, stomach pain, increased weight, headache, altered mood, and breast pain. Most of these symptoms are temporary. However, if they persist, check with your doctor as soon as possible.

Q: How long will Krimson 35 Tablet take to reduce acne?

A: Usually, you will be able to notice improvements within 3-4 weeks. However, it is important to finish the full course of management to see its full benefit. Inform your doctor if your acne did not get cured even after finishing the full course of management.

Q: Can children use Krimson 35 Tablet?

A: Krimson 35 Tablet is generally not recommended for pre-pubertal children. It may be prescribed for adolescents after the onset of menstruation under medical supervision.

Q: Is Krimson 35 Tablet suitable for elderly women?

A: Krimson 35 Tablet is generally not intended for postmenopausal women. A healthcare professional will assess individual suitability based on age, medical history, and overall health status.

Q: What should I do if I experience an allergic reaction to Krimson 35 Tablet?

A: Stop taking the medicine and seek immediate medical attention if you develop symptoms such as rash, itching, swelling of the face or throat, or difficulty breathing.

References

  1. L Falsetti , E Galbignani. Long-term treatment with the combination ethinylestradiol and cyproterone acetate in polycystic ovary syndrome. Pubmed. NIH. [Accessed on 24th June 2026] [Revised in December]  
  2. Generics (UK) Limited. HPRA. [Accessed on 24th June 2026] [Revised in December 2012]  
  3. Gestra 35. Gynogen captap. [Accessed on 24th June 2026]  

     

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