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Introduction About KINPRIDE 1MG TABLET
KINPRIDE 1MG TABLET contains Cinitapride which belongs to the group of medicines called Gastro-prokinetic agents. KINPRIDE 1MG TABLET is used to manage gastroesophageal reflux disease and functional gastrointestinal motility disorders (disease marked by persistent and recurring gastrointestinal symptoms) in affected individuals.
KINPRIDE 1MG TABLET is not recommended for use in patients allergic to Cinitapride. It is also not recommended for use in patients with gastrointestinal bleeding/obstruction/perforation and in patients with a history of neuroleptic-induced tardive dyskinesia (condition marked by involuntary movements of head, neck, trunk or limbs).
Before taking KINPRIDE 1MG TABLET, inform your doctor if you have intolerance to certain sugars (such as lactose), liver disease (such as primary/secondary liver tumors, hepatocellular carcinoma) and/or kidney disease (such as acute renal injury/failure).
KINPRIDE 1MG TABLET is not recommended for use in pregnant and breastfeeding women. It is also not recommended for use in children & adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 65 years/above) after consulting the doctor.
The most common side effects of taking KINPRIDE 1MG TABLET are abdominal discomfort, nausea and/or diarrhea. Consult your doctor if any of these symptoms worsen.
Uses Of KINPRIDE 1MG TABLET
- Manage gastroesophageal reflux disease
- Manage functional gastrointestinal motility disorders in affected individuals
How KINPRIDE 1MG TABLET Works
KINPRIDE 1MG TABLET works by increasing the gastrointestinal movement by enhancing the frequency and strength of stomach muscle contractions which leads to increased gastric motility & emptying thus improving gastro-duodenal coordination and managing the occurrence of gastroesophageal reflux disease in affected individuals.
How to use KINPRIDE 1MG TABLET
Take KINPRIDE 1MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of KINPRIDE 1MG TABLET
Common
- abdominal discomfort
- diarrhea
- nausea
Rare
- signs of allergic skin reactions such as rash, itching
- gynecomastia (swelling of male breast tissue)
- angioedema (swelling under the skin)
- spasm in the muscles of face, neck and tongue
How To Manage Side Effects
Nausea and vomiting:
Try to take KINPRIDE 1MG TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if symptom gets worse.
Diarrhea:
Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult your doctor and inform them if the symptom gets worse.
Warning & Precautions
Pregnancy
KINPRIDE 1MG TABLET is not recommended for use in pregnant women. Consult your doctor before taking the medicine.
Breastfeeding
KINPRIDE 1MG TABLET is generally not recommended for use in breastfeeding women. Consult your doctor before taking the medicine.
Driving and Using Machines
Do not drive or use heavy machinery while taking KINPRIDE 1MG TABLET as it may affect your ability to drive or use heavy machinery.
Alcohol
Avoid consumption of alcohol while taking KINPRIDE 1MG TABLET because it might enhance the sedative effects of the medicine.
Kidney
KINPRIDE 1MG TABLET should be used with caution in patients with kidney diseases such as acute renal injury/failure. Consult your doctor before taking the medicine.
Liver
KINPRIDE 1MG TABLET should be used with caution in patients with liver diseases such as primary/secondary liver tumors, hepatocellular carcinoma. Consult your doctor before taking the medicine.
Allergy
Do not take KINPRIDE 1MG TABLET if you are allergic to cinitapride or any of the other ingredients of this medicine. Consult your doctor before taking the medicine.
Others
KINPRIDE 1MG TABLET is not recommended for use if you have:
- gastrointestinal bleeding, obstruction or perforation with stimulating gastric motility
- history of neuroleptic-induced tardive dyskinesia (rapid, repeated movements of the head, neck, trunk or limbs)
Before taking KINPRIDE 1MG TABLET, inform your doctor if you:
- intolerance to certain sugars such as lactose
Use in Pediatrics:
KINPRIDE 1MG TABLET is not recommended for use in children and adolescents (aged below 18 years). Consult your doctor before taking the medicine.
Use in Geriatrics:
KINPRIDE 1MG TABLET should be used with caution in elderly patients (aged above 65 years) especially with type 2 diabetes. Consult your doctor before taking the medicine.
Interactions
A. Drug - Drug interactions:
Before taking KINPRIDE 1MG TABLET, inform your doctor if you are taking:
- phenothiazine (used to manage serious mental and emotional disorders)
- other antidopaminergic drugs (used as a non-addictive alternative to manage withdrawal, agitation and anxiety in patients with alcohol dependence) Ex. risperidone, olanzapine
- digoxin (used to manage heart failure)
- anticholinergic drugs (used to manage various conditions such as urinary incontinence, overactive bladder, asthma, diarrhea, motion sickness) Ex. atropine, clidinium, cyclopentolate
- opioid analgesics (used to relieve moderate or intense pain) Ex. codeine, fentanyl
- medicine used to manage nervous system diseases, insomnia. Ex. amitriptyline
- medicine used to manage Parkinson’s disease (Ex. levodopa)
- medicine used to manage abdominal pain (Ex. ibuprofen)
- medicine used to manage respiratory disease such as chronic bronchitis. (Ex. albuterol)
Overdosage:
If you or anyone else accidentally took too much of KINPRIDE 1MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include drowsiness, disorientation and/or extrapyramidal reactions (such as involuntary muscle movements of face, neck and tongue).
Synopsis
| Drug | : | Cinitapride |
| Pharmacological Category | : | Pro-kinetic drug |
| Therapeutic Indication | : | Gastroesophageal reflux disease, Functional gastrointestinal motility disorders |
| Dosage Forms | : | Tablet |
More Information
- Keep KINPRIDE 1MG TABLET out of reach of children
- Store the medicine below 30°C
FAQs About KINPRIDE 1MG TABLET
What are the side effects of KINPRIDE 1MG TABLET?
The most common side effects of taking KINPRIDE 1MG TABLET are abdominal discomfort, diarrhea and nausea. Contact your doctor if any of these symptoms worsen or needs immediate care.
How much dose can KINPRIDE 1MG TABLET be taken in a day?
Take KINPRIDE 1MG TABLET as advised by your physician. Do not crush or chew the medicine. Swallow the medicine with a glass of water. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Does KINPRIDE 1MG TABLET cause diarrhea?
Yes, KINPRIDE 1MG TABLET causes diarrhea as it is the most common side effect associated with the use of KINPRIDE 1MG TABLET. If you experience any such effect, then try to drink lots of fluids such as water/fruit juices to keep yourself hydrated and avoid taking any medicine on your own to manage the condition. Consult your doctor if the symptom does not improve.
Can KINPRIDE 1MG TABLET be used in children?
No, KINPRIDE 1MG TABLET is not recommended for use in children and adolescents (aged below 18 years). If KINPRIDE 1MG TABLET is accidentally ingested by a child or adolescent, go to the hospital immediately and consult the doctor for further management.
Is it safe to use KINPRIDE 1MG TABLET in pregnant and breastfeeding women?
No, KINPRIDE 1MG TABLET is not recommended to be used during pregnancy as a precautionary measure which is also not recommended to be used in breastfeeding women since it might pass through breastfed milk. Consult your doctor before taking the medicine.
References
1. K D Tripathi. Gastrointestinal Drugs. Essentials Of Medical Pharmacology. Eighth Edition. 2019. Page 716
2. Iago Rodríguez-Lago, Cristina Carretero, Maite Herráiz, José C Subtil, Maite Betés, Macarena Rodríguez-Fraile, Jesús J Sola, José I Bilbao, Miguel Muñoz-Navas and Bruno Sangro. Long-term follow-up study of gastroduodenal lesions after radioembolization of hepatic tumors. NIH National Library of Medicine. National center for biotechnology information. PMC PubMed Central. May 2013. [Accessed on 10th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660818/
3. Rajeev Raghavan and Garabed Eknoyan. Acute interstitial nephritis – a reappraisal and update. NIH National Library of Medicine. National center for biotechnology information. PMC PubMed Central. September 2014. [Accessed on 10th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928030/
4. Prakash Tendulkar, Ravi Kant, Satyavati Rana, Poonam Yadav, Anissa A Mirza and Disha Agarwal. Efficacy of Pro-Kinetic Agents in Type 2 Diabetes Mellitus Patients With Gastroparesis Using Lactulose Hydrogen Breath Testing: A Randomized Trial. NIH National Library of Medicine. National center for biotechnology information. PMC PubMed Central. January 2022. [Accessed on 10th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817741/
5. Rapat Pittayanon, Yuhong Yuan, Natasha P Bollegala, Reena Khanna, Grigorios I Leontiadis, Paul Moayyedi. Prokinetics for functional dyspepsia. NIH National Library of Medicine. National Center for Biotechnology Information. October 2018. [Accessed on 10th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516965/
6. LABORATORIOS NORMON, S.A. Cinitrex tablets. [Revised in June 2018] [Accessed on 10th May 2022] https://medicarcp.com/website/pdf/pils/9149%20-%20en.pdf
7. Getz Pharma (Pvt) Ltd. Cinita. [Accessed on 10th May 2022] https://getzpharma.com/wp-content/uploads/2016/07/Cinita-Tab-Leaflet-Export-GA.pdf
8. Aar Ess Remedies Private Limited. Citipride-SR. [Accessed on 10th May 2022]. http://www.aaressremedies.com/productpage/citipride-sr/
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