KEZRIN B Cream 20gm
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Introduction About KEZRIN B CREAM
KEZRIN B CREAM is a combination of Beclomethasone and Ketoconazole, which belong to the groups of medicines called Anti-inflammatory and Antifungal respectively. It is used to manage different kinds of fungal infections like Tinea corporis (Ringworm), Tinea pedis (Athlete's foot), Tinea cruris (Jock itch), and Tinea capitis (Ringworm of the scalp).
These fungal infections can spread easily from one person to another and cause redness and itching in the affected area. They are usually seen in moist and sweaty areas of the body as tinea pedis is usually seen in between the toes due to fitting shoes whereas tinea cruris and groin are seen in the inner thigh region.
Avoid applying KEZRIN B CREAM on the skin surface that is cut, scraped, sunburned, or eczema affected. KEZRIN B CREAM is not recommended for use in patients suffering from skin-related viral infections, tuberculosis, acne rosacea, and perioral dermatitis.
KEZRIN B CREAM should be used with caution in pregnancy and breastfeeding women unless considered necessary. KEZRIN B CREAM is not recommended for use in children 9 years of age and below. KEZRIN B CREAM should be used with caution in elderly patients (aged 65 years or above).
The most common side effects of this medicine are application site reactions such as burning, irritation, itching, and redness. Contact your physician if any of the above symptoms worsen.
Uses Of KEZRIN B CREAM
Manages fungal infections such as:
- ringworm (Tinea corporis)
- tinea pedis (Athlete's foot)
- tinea cruris (Jock itch)
- tinea capitis (Ringworm of the scalp)
How KEZRIN B CREAM Works
KEZRIN B CREAM is a combination of Beclomethasone and Ketoconazole. Beclomethasone is a corticosteroid that works by reducing inflammation and relieving symptoms like itching, redness, irritation, and swelling by blocking the enzymes responsible for causing it (prostaglandins and leukotrienes). Ketoconazole is an imidazole that blocks the synthesis of ergosterol, a key component of the fungal cell membrane, thus weakening the structure and function of the fungal cell membrane.
How to use KEZRIN B CREAM
Apply KEZRIN B CREAM as directed by your physician. It is for external use only. Clean the skin and dry the skin area to be managed. Wash your hands with soap and water and apply a thin layer of the medicine to the affected area of the skin and rub it gently. Avoid contact with the eyes, nose, mouth, or inside the vagina. Do not cover or wrap or bandage the skin unless directed by the doctor.
Side Effects Of KEZRIN B CREAM
Common
- reaction at the site of application (like burning, irritation, itching, and redness)
- pruritis
- stinging sensation
- oily and dry scalp
- mild hair loss
Uncommon
- bleeding
- discomfort
- dryness
- inflammation (contact dermatitis)
- tingling
- hives, rash (also known as nettle rash or urticaria)
- sticky skin
Rare
Stop applying KEZRIN B CREAM and contact your physician immediately if you experience any of the following side effects:
- skin condition gets worse, and develops a generalised rash or skin becomes swollen during management
- get raised bumps with pus under the skin (pustular psoriasis)
- Peeling or blistering of the skin
How To Manage Side Effects
Skin rash Or Itching
Avoid hot showers because hot water can irritate the skin. Do not scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if the itching worsens.
Warning & Precautions
Pregnancy
Use with CautionKEZRIN B CREAM should be used with caution in pregnancy unless considered necessary. Contact your doctor before applying KEZRIN B CREAM.
Breastfeeding
Use with CautionKEZRIN B CREAM should be used with caution in breastfeeding women as it is not known whether it may pass through breast milk. Contact your doctor before applying KEZRIN B CREAM.
Allergy
ContraindicatedDo not apply KEZRIN B CREAM if you are allergic to Beclomethasone, Ketoconazole, or other corticosteroids, or other ingredients of this medicine.
Use In Pediatrics
ContraindicatedKEZRIN B CREAM is not recommended for use in children 9 years of age and below unless necessary. Contact your doctor before applying KEZRIN B CREAM.
Use In Geriatrics
Use with CautionKEZRIN B CREAM should be used with caution in elderly patients (aged 65 years or above). Contact your doctor before applying KEZRIN B CREAM.
Others
KEZRIN B CREAM is not recommended for use if you have:
- skin-related viral infections
- tuberculosis
- perioral dermatitis
- acne or rosacea (skin condition affecting the face)
Interactions
A. Drug-Drug interactions:
Tell your doctor if you are applying for or have recently taken any other medicines, including medicines obtained without a prescription, vitamin supplements or herbal products.
Overdosage:
If you or anyone else accidentally use too much of KEZRIN B CREAM or if you or a child accidentally swallow the medicine, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Beclomethasone, Ketoconazole |
| Pharmacological Category | : | Anti-inflammatory, Antifungal |
| Therapeutic Indication | : | Fungal Infections |
| Dosage Forms | : | Cream, Lotion |
More Information
- Keep out of reach from children
- Store KEZRIN B CREAM below 25°C
FAQs About KEZRIN B CREAM
Q: Can I use KEZRIN B CREAM in children?
A: No. KEZRIN B CREAM is not recommended for use in children 9 years of age and below unless necessary. Contact your doctor before applying KEZRIN B CREAM.
Q: How to apply KEZRIN B CREAM?
A: Apply KEZRIN B CREAM as directed by your physician. It is for external use only. Clean the skin and dry the skin to be managed. Wash your hands with soap and water and apply a thin layer of the medicine to the affected area of the skin and rub it gently. Avoid contact with the eyes, nose, mouth, or inside the vagina. Do not cover or wrap or bandage the skin unless directed by the doctor.
Q: What for KEZRIN B CREAM used?
A: KEZRIN B CREAM is used to manage different kinds of fungal infections like Tinea corporis (Ringworm), Tinea pedis (Athlete's foot), Tinea cruris (Jock itch), and Tinea capitis (Ringworm of the scalp).
Q: How KEZRIN B CREAM works?
A: KEZRIN B CREAM is a combination of Beclomethasone and Ketoconazole. Beclomethasone is a corticosteroid that works by reducing inflammation and relieving symptoms like itching, redness, irritation, and swelling by blocking the enzymes responsible for causing it (prostaglandins and leukotrienes). Ketoconazole is an imidazole that blocks the synthesis of ergosterol, a key component of the fungal cell membrane, thus weakening the structure and function of the fungal cell membrane.
Q: When to avoid KEZRIN B CREAM?
A: KEZRIN B CREAM is not recommended for use in patients suffering from skin-related viral infections, tuberculosis, acne rosacea, and perioral dermatitis. Contact your doctor before applying KEZRIN B CREAM.
References
1. KD Tripathi. Corticosteroids, Antifungal drugs & Aminoglycoside Antibiotics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 289,792, 750.
2. Bethesda (MD). Beclomethasone. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 29th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/20469
3. Bethesda (MD). Ketoconazole. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 29th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/3823
4. Beclomethasone and Ketoconazole. www.bionova.co.in. [Accessed on 29th June 2022] https://www.bionova.co.in/ketosh-b-cream.html
5. Beclomethasone and Ketoconazole. www.canbro.in. [Accessed on 29th June 2022] https://www.canbro.in/product/danzol-b
6. Accord Ltd. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on 29th June 2022] https://www.medicines.org.uk/emc/files/pil.5023.pdf
7. Janssen Pharmaceutica. Medicines Compendium (EMC). [Revised in March 2021] [Accessed on 29th June 2022] https://www.medicines.org.uk/emc/files/pil.970.pdf
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