Ketorol DT 10mg Tablet 15'S
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Introduction About KETOROL DT 10MG TABLET
KETOROL DT 10MG TABLET contains Ketorolac, which belongs to the group of medicines called Painkillers. It is used for short-term pain relief (5 or 7 days) of sudden moderate to severe pain associated with surgical procedures (such as general surgery, orthopaedic and dental surgery), Musculo-skeletal pain (such as severe joint pain, muscle pain), post-partum uterine cramping pain and other pain conditions when your doctor prescribes.
Take KETOROL DT 10MG TABLET only under medical supervision. It can be taken with or without food. Take this medicine only for the duration as advised by your physician. Usually, it is not taken more than 7 days without doctor consultation.
KETOROL DT 10MG TABLET is not recommended for use in patients taking other NSAIDs (Ex. aspirin) or those having advanced kidney, heart, cerebrovascular or gastrointestinal diseases or a tendency to bleed easily. Before taking KETOROL DT 10MG TABLET, inform your doctor if you have liver, lung or heart diseases, high blood pressure or inflammatory bowel diseases.
KETOROL DT 10MG TABLET is not recommended for use in pregnancy (especially during the last 3 months) and in breastfeeding mothers. KETOROL DT 10MG TABLET is not recommended for use in children (below 17 years of age). KETOROL DT 10MG TABLET should be used with caution in elderly patients above 65 years of age.
Avoid smoking and consumption of alcohol with KETOROL DT 10MG TABLET. The most common side effects of taking KETOROL DT 10MG TABLET include nausea, indigestion, stomach pain, diarrhoea, dizziness or drowsiness, headache or swelling. Consult your doctor immediately if the symptoms worsen or persist.
Uses Of KETOROL DT 10MG TABLET
It is used for short-term pain relief (5 or 7 days) of sudden moderate to severe pain associated with:
- Surgical procedures (such as general surgery, orthopaedic and dental surgery)
- Musculo-skeletal pain (such as severe joint pain, muscle pain)
- Post-partum uterine cramping pain
- Other pain conditions when your doctor prescribes
How KETOROL DT 10MG TABLET Works
KETOROL DT 10MG TABLET contains Ketorolac which works by blocking enzymes called COX-1 and COX-2, which are involved in producing chemicals (prostaglandins) that cause pain and inflammation. By stopping these enzymes, ketorolac helps reduce pain, swelling, and inflammation in the body.
How to use KETOROL DT 10MG TABLET
Take KETOROL DT 10MG TABLET as advised by your physician. It can be taken with or without food.
For Tablet, Capsule: Swallow KETOROL DT 10MG TABLET with a glass of water. Do not crush or chew the medicine.
For Dispersible Tablet: Disperse KETOROL DT 10MG TABLET in the specified quantity of water as mentioned in the label. Consume the mixture immediately after reconstitution.
Your doctor will decide the correct dose and duration of KETOROL DT 10MG TABLET therapy for you depending upon your age, body weight and disease condition. Continue to take KETOROL DT 10MG TABLET for the stipulated duration prescribed by your doctor to achieve better results.
Side Effects Of KETOROL DT 10MG TABLET
Common
- nausea, indigestion, stomach pain, diarrhea, constipation
- dizziness, drowsiness, headache
- swelling
- sleepiness or lack of sleep
- nervousness
- fever
Uncommon
- abnormal dreams, anxiety, dry mouth, hyperactivity, tingling and prickling sensation, increased sweating, euphoria, hallucinations
- loss of appetite, gas, vomiting, inflamed and sore mouth, gastritis, sore throat
- lack of energy, pain, back pain
- vasodilatation, throbbing sensation, high blood pressure
- migraine
- muscle or joint pain
- rash, hives
- discomfort, pain or burning while peeing
Rare
- worsening of inflammatory bowel disease like ulcerative colitis or Crohn’s disease, ulcerative stomatitis
- blood disorders like agranulocytosis, hemolytic anemia, aplastic anemia, lymphadenopathy, pancytopenia (due to changes in the number of blood cells)
- postoperative bleeding
- increased blood sugar levels
- high potassium levels (shortness of breath, chest pain, nausea, vomiting)
- low sodium levels (whole body dizziness, fatigue, lethargy, weakness, thirst)
- aseptic meningitis (brain and spinal cord membrane inflammation), psychosis, fits
- bronchospasm (tightness of chest), pneumonia, respiratory depression
- conjunctivitis (eye inflammation)
Stop taking KETOROL DT 10MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- shortness of breath
- swelling, rapid weight gain
- skin rash
- bleeding in stomach (bloody or tarry stools, coughing up blood or vomit that may look like coffee grounds)
- liver problems (nausea, stomach pain, itchiness, tiredness, flu-like symptoms, clay-coloured stools, dark urine, yellowing of the skin or eyes, loss of appetite)
- anaemia (paleness of skin, light-headedness, fast heart rate, difficulty in concentrating, shortness of breath)
- kidney problems (little or no urine production, difficulty or pain while urinating, swelling of legs, tiredness, shortness of breath)
- heart attack or stroke (chest pain spreading to jaw or shoulder, slurred speech, sudden numbness or weakness on one side of the body, feeling short of breath)
- allergic reaction (hives, difficulty in breathing, swelling of face or throat)
- severe skin reaction (fever, burning eyes, sore throat, skin pain, purple or red skin rash that spreads and causes blistering and peeling)
- flank pain with or without haematuria, haemolytic uraemic syndrome (damage or inflammation of small blood vessels in kidneys)
How To Manage Side Effects
Constipation
Eat plenty of fiber rich foods such as vegetables, fresh fruits and cereals and drink plenty of water. Exercise more regularly. If symptom persists, contact your doctor.
Diarrhea
Drink lots of fluids, such as water or fruit juice for hydration. Do not consume any medicine on your own without asking your doctor. If symptom persists, contact your doctor.
Dizziness Or Drowsiness
When you feel dizzy, lie or sit down immediately. Lie-down in a dark and quite place with eyes closed. Vehicle driving should be avoided if you experience frequent dizziness without warning. If symptom persists, contact your doctor.
Dry Mouth
Dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying. If symptom persists, contact your doctor.
Headache
Try to take rest in a quiet dark room. Don’t involve yourself in exertive activities. Apply a pain-relieving balm on your forehead. If symptom persists, contact your doctor.
Nausea And Vomiting
Drink ice cold drinks. Try to avoid sugary snacks and drinks. Avoid drinking too much liquid along with your meals, drink slowly in between meals. Take KETOROL DT 10MG TABLET with or just after meals. Stick to simple meals. Avoid eating rich or spicy food. If symptom persists, contact your doctor.
Stomach Pain
Try to rest and relax. Try to have smaller and frequent meals. Keep a heat pad on your stomach. If symptom persists, contact your doctor.
Warning & Precautions
Pregnancy
ContraindicatedKETOROL DT 10MG TABLET is not recommended in women who are pregnant (especially during the last 3 months) or trying to get pregnant as it may harm the baby. Consult your doctor for advice.
Breastfeeding
ContraindicatedKETOROL DT 10MG TABLET is not recommended for use in breastfeeding mothers. Consult your doctor for advice.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel dizzy, drowsy, tired or light-headed after taking KETOROL DT 10MG TABLET.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking KETOROL DT 10MG TABLET because you would be more likely to develop stomach problems.
Kidney
Consult your doctorKETOROL DT 10MG TABLET is not recommended for use in patients with severe kidney disease. KETOROL DT 10MG TABLET should be used with caution in patients with other kidney problems. Consult your doctor for advice.
Liver
Use with CautionKETOROL DT 10MG TABLET should be used with caution in patients with impaired liver function, history of liver disease or any biliary problem. Consult your doctor for advice.
Allergy
ContraindicatedDo not take KETOROL DT 10MG TABLET if you are allergic to Ketorolac tromethamine, aspirin or other similar medicines or any of the other ingredients of this medicine.
Lungs
Use with CautionKETOROL DT 10MG TABLET should be used with caution in patients with a family history of asthma, nasal polyps, chronic sinusitis (long-term swelling of the sinus) or hives. Consult your doctor for advice.
Heart Disease
Consult your doctorKETOROL DT 10MG TABLET is not recommended for use if you had or are going to have a heart bypass surgery, have severe uncontrolled heart failure. KETOROL DT 10MG TABLET should be used with caution in patients who have or had high blood pressure, angina, heart attack, congestive heart failure or atherosclerosis (thickening or hardening of your artery walls). Consult your doctor for advice.
Use In Pediatrics
ContraindicatedKETOROL DT 10MG TABLET is not recommended for use in children. The safety and effectiveness of KETOROL DT 10MG TABLET in children and adolescents (below 17 years of age) have not been established. Consult your child’s doctor for advice.
Use In Geriatrics
Use with CautionKETOROL DT 10MG TABLET should be used with caution in elderly patients above 65 years of age. Your doctor may prescribe you lower dosages. Consult your doctor for advice.
Others
KETOROL DT 10MG TABLET is not recommended for use if you:
- have or had peptic ulcer and gastrointestinal bleeding or perforation
- have to undergo any major surgery
- tend to bleed easily
- have cerebrovascular bleeding
- have incomplete haemostasis (blood clotting), high risk of bleeding
- had an asthma attack, hives or other allergic reactions after taking aspirin or any other NSAIDs
- are going to take it for pain, right before or after heart bypass surgery
- smoke
Before taking KETOROL DT 10MG TABLET, inform your physician if you have:
- high cholesterol
- diabetes mellitus or are on a low sugar diet
- poor circulation to your extremities
- pancreatic problems
Interactions
A. Drug-Drug interactions:
Before taking KETOROL DT 10MG TABLET, inform your doctor if you are taking any of the following medicines:
- Antidepressants (Ex. fluvoxamine, sertraline, trazodone, citalopram, fluoxetine, escitalopram, paroxetine, vilazodone)
- lithium (used to manage mania)
- Anti-psychotics (Ex. thiothixene, alprazolam)
- Pain killers (Ex. ibuprofen, indomethacin, ketorolac, aspirin, celecoxib, diclofenac, meloxicam, naproxen)
- methotrexate (medicine used in cancer management)
- Anticoagulants (Ex. warfarin, heparin, clopidogrel)
- Cardiac drugs (Ex. furosemide, hydrochlorothiazide, enalapril, lisinopril, perindopril, ramipril, candesartan, irbesartan, losartan, valsartan, digoxin)
- Antiepileptics (Ex. phenytoin, carbamazepine)
- prednisolone (used to manage autoimmune and inflammatory diseases)
- cyclosporin (used to supress immunity)
- morphine (used in extreme pain)
- oxpentiphylline (used to manage blood flow problems in legs or arms)
- probenecid (used to manage gout)
Overdosage:
If you or anyone accidentally use too much of KETOROL DT 10MG TABLET, consult your doctor immediately or visit the nearby hospital as it may increase the risk of side effects. Symptoms of KETOROL DT 10MG TABLET overdosage may include drowsiness, nausea, vomiting and upper abdomen pain, lethargy.
Synopsis
| Drug | : | Ketorolac tromethamine |
| Pharmacological Category | : | Nonsteroidal Anti-inflammatory Drugs |
| Therapeutic Indication | : | Pain management |
| Dosage Forms | : | Tablet, Dispersible tablet, Injection, Gel, Eye drops, Solution, Opthalmic Solution |
More Information
Storage
- Keep KETOROL DT 10MG TABLET out of reach of children
- Store KETOROL DT 10MG TABLET below 30°C
FAQs About KETOROL DT 10MG TABLET
Q: What is Ketorol DT 10 used for?
A: Ketorol-DT is primarily used for the short-term relief of moderate to severe pain, such as postoperative pain, musculoskeletal injuries, and other acute pain conditions.
Q: How does Ketorol DT 10 work?
A: Ketorolac, the active ingredient in Ketorol-DT, inhibits cyclooxygenase (COX) enzymes, reducing the synthesis of prostaglandins compounds that mediate pain, inflammation, and fever.
Q: How should Ketorol DT 10 be taken?
A: Dosage: Typically, 10 mg every 4 to 6 hours as needed, not exceeding 40 mg per day. Administration: Dissolve the tablet in water before ingestion. Duration: Use is generally limited to a maximum of 5 days to minimize adverse effects.
Q: What are the common side effects of Ketorol DT 10?
A: Common side effects include nausea, stomach pain, indigestion, diarrhea, drowsiness and headache. Consult your doctor if these side effects persist or worsen.
Q: Can Ketorol DT 10 be taken during pregnancy or breastfeeding?
A: Pregnancy: Contraindicated in the third trimester due to risks like premature closure of the fetal ductus arteriosus. Use during the first and second trimesters only if clearly needed and prescribed by a doctor. Breastfeeding: Ketorolac passes into breast milk, consult your doctor before us.
Q: Is Ketorol DT 10 safe for long-term use?
A: No, long-term use increases the risk of serious cardiovascular and gastrointestinal events. It's intended for short-term use only, typically not exceeding 5 days.
Q: Can it be taken with other painkillers?
A: Avoid combining Ketorol-DT with other NSAIDs or aspirin to reduce the risk of adverse effects. Always consult your doctor before combining it with other medications.
Q: Who should avoid using Ketorol DT 10?
A: Individuals with Active peptic ulcers, Recent gastrointestinal bleeding, Severe kidney or liver impairment, Hypersensitivity to NSAIDs, History of asthma attacks triggered by NSAIDs should avoid using Ketorol-DT.
Q: Can Ketorol DT 10 cause addiction?
A: No, Ketorol-DT is not habit-forming and does not cause addiction.
Q: What should I do if I miss a dose?
A: If prescribed on a regular schedule and you miss a dose, take it as soon as you remember. If it's near the time for the next dose, skip the missed dose. Do not double the dose to catch up.
Q: What is the usual dosage for Ketorol-DT?
A: The typical dosage is 10 mg every 4 to 6 hours as needed, not exceeding 40 mg per day. Treatment duration should not surpass 5 days.
Q: Can I take Ketorol-DT on an empty stomach?
A: It's advisable to take Ketorol-DT with food or after meals to minimize gastrointestinal discomfort.
Q: Can Ketorol-DT be used for children?
A: Ketorol-DT is generally not recommended for children under 16 years of age. Consult a pediatrician for appropriate alternatives.
References
1. KD. Tripathi. NSAIDs and Antipyretic-Analgesics. Essentials of medical pharmacology. Eighth edition. 2019. Page-218.
2. Ahmad N. Mahmoodi; Peggy Y. Kim. Ketorolac. NIH National Library of Medicine, National center for biotechnology information. StatPearls [Internet]. April 2022. [Accessed on 12th August 2024] https://www.ncbi.nlm.nih.gov/books/NBK545172/
3. Tom Mallinson. A review of ketorolac as a prehospital analgesic. ReserachGate. December 2017. [Accessed on 12th August 2024] https://www.researchgate.net/publication/321640488_A_review_of_ketorolac_as_a_prehospital_analgesic
4. Innova Cap Tab Ltd. Torodent DT (Ketorolac Trimethamine). Ciplamed. [Revised in September 2020]. [Accessed on 12th August 2024] https://ciplamed.com/content/torodent-dt
5. Apotex Inc. Apo-ketorolac (Ketorolac Trimethamine). [Revised in October 2017] [Accessed 12th August 2024] https://pdf.hres.ca/dpd_pm/00041526.PDF
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