Torque Pharmaceuticals Pvt Ltd

KETOMAC Cream 15g

Fungal Infections
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    Introduction About KETOMAC CREAM

    KETOMAC CREAM is used to manage fungal skin infections. It can be applied on your hands, feet, genital area, trunk, scalp, face and chest.

    It contains an antifungal agent called Ketoconazole which works by stopping the growth of fungi. Use KETOMAC CREAM as advised by your physician. Apply the required amount of the medicine to the affected skin areas.

    Before applying KETOMAC CREAM, inform your doctor if you are using a cream, ointment or lotion that contains a steroid.

    KETOMAC CREAM can be used if you are pregnant or breast-feeding, however, consult your doctor for advice. KETOMAC CREAM is not recommended for use in children and adolescents (under 18 years of age).

    The most common side effects of applying KETOMAC CREAM are burning sensation, skin redness, or itching. If any of the symptoms worsen, contact your doctor.

    Uses Of KETOMAC CREAM

    • Management of fungal skin infections

    How KETOMAC CREAM Works

    KETOMAC CREAM contains Ketoconazole which works by stopping the growth of fungi. It blocks the production of a substance called ergosterol, which is essential for the fungi's cell membrane. Without ergosterol, the cell membrane becomes weak, causing the fungi to die and the infection to clear up.

    How to use KETOMAC CREAM

    Apply KETOMAC CREAM as advised by your physician. It is for external use only. Wash the infected area and dry it well.  Apply it to the affected and immediate surrounding area with clean fingers. Unless the affected skin is on your hands, wash your hands with soap and water after using KETOMAC CREAM in order to stop you from spreading the infection to other parts of your body or to other people.

    Keep using KETOMAC CREAM until a few days after all symptoms have completely disappeared. This is to manage your symptoms from recurring.

    Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Usually, you will see improvement after 4 weeks but if you don’t, talk to your doctor.

    Side Effects Of KETOMAC CREAM

    Common

    • burning sensation
    • skin redness or itching

    Uncommon

    • hypersensitivity
    • raised blisters or inflammation of the skin
    • shedding of the skin
    • problems where the medicine is applied (bleeding, discomfort, dryness, inflammation, tingling)
    • skin irritation like rash
    • sticky skin

    Stop applying KETOMAC CREAM and contact your doctor immediately if you experience any of the following side effects:

    • severe irritation or reddening of the skin where the medicine has been applied, or other signs of allergy during initial management days
    • peeling or blistering of the skin

     

    How To Manage Side Effects

    Skin rash Or Itching

    Applying a cold compress, damp cloth, or cool showers can bring immediate relief to swelling and reduce itching. Avoid hot showers because hot water can further irritate your skin. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if your skin rash persists.

    Warning & Precautions

    Pregnancy

    Consult your doctor

    KETOMAC CREAM can be used if you are pregnant, however, consult your doctor for advice.

    Breastfeeding

    Consult your doctor

    KETOMAC CREAM can be used if you are breast-feeding, however, consult your doctor for advice.

    Driving and Using Machines

    Use with Caution

    KETOMAC CREAM is unlikely to affect your ability to drive or to use machinery.

    Allergy

    Contraindicated

    Do not apply KETOMAC CREAM if you are allergic to Ketoconazole or any of the other ingredients of this medicine.

    Use In Pediatrics

    Contraindicated

    KETOMAC CREAM is not recommended for use in children and adolescents (under 18 years of age). Consult your child’s doctor for advice.

    Others

    KETOMAC CREAM is not recommended for eye infections. Consult your doctor for advice.

    Interactions

    A. Drug-Drug interactions:

    Before applying KETOMAC CREAM, inform your doctor if you are using the following medicines:

    • medicines used to manage inflammatory conditions (Ex. betamethasone, hydrocortisone)

    Overdosage:

    If you or anyone else accidentally apply too much of KETOMAC CREAM, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include burning sensation, redness or swelling.

    Synopsis

    Drug :   Ketoconazole
    Pharmacological Category :   Azole antifungal
    Therapeutic Indication :   Fungal infections         
    Dosage Forms :   Tablet, Solution, Scalp Solution, Cream, Gel, Lotion, Ointment, Shampoo, Soap, Body Wash, Bar, Eye Drops, Dusting Powder, Scrub 

    More Information

    Storage

    • Keep KETOMAC CREAM out of reach of children
    • Do not store above 25°C

    FAQs About KETOMAC CREAM

    Q: What does KETOMAC CREAM contain?

    A: KETOMAC CREAM contains Ketoconazole which belongs to the group of medicines called Antifungals.

    Q: What is KETOMAC CREAM used for?

    A: It is used in adults to manage fungal skin infections which may appear on the skin of the hands, feet, genital area, trunk, groin, scalp, face, chest or back.

    Q: How does KETOMAC CREAM work?

    A: KETOMAC CREAM reduces fungal infection by inhibiting the growth of the fungus by weakening the structure and function of the fungal cell membrane.

    Q: How often should I apply KETOMAC CREAM?

    A: Your doctor will decide the correct dose and duration of KETOMAC CREAM for you depending upon your age, body weight and disease condition. Depending on the infection type, management may last 2 to 6 weeks. Do not apply it for more duration than advised by your doctor.

    Q: What if I swallow KETOMAC CREAM?

    A: Accidental swallowing of small quantities of KETOMAC CREAM is usually harmless but, consult your doctor immediately if you or anyone else swallow it. Take the medicine with you for the doctor to know what you have ingested.

    Q: How do I apply KETOMAC CREAM?

    A: Apply KETOMAC CREAM as directed by your physician. Wash the infected area and dry it properly. Keep a towel and a flannel for your personal use to manage infecting anyone else. Apply the medicine gently into the affected area and surrounding skin with clean fingers. Clothing which touches the infected areas should be washed and changed frequently. Consult your doctor if you have any doubts regarding its use.

    Q: What if I forget to apply KETOMAC CREAM?

    A: If you forget to apply KETOMAC CREAM, use as per the directions next time you apply it. Do not use the medicine two times to make up for the missed dose.

    Q: Can I stop applying KETOMAC CREAM?

    A: Do not stop applying KETOMAC CREAM without asking your doctor. You will usually see signs of improvement after 4 weeks. If not, talk to your doctor. Continue using the medicine until a few days after all symptoms have completely disappeared. Even after your skin is completely cured, you sometimes have to apply the medicine once weekly or once per 2 weeks to manage your symptoms from coming back.

    Q: Can I use other medicines with KETOMAC CREAM for my skin condition?

    A: Before using KETOMAC CREAM, inform your doctor if you are taking, have taken, or might take any other medicine, including prescription, over the counter or any herbal medicine. If you have been regularly using a lotion or cream, containing a steroid (Ex. betamethasone or hydrocortisone) for your skin condition, you should wait for two weeks before starting management with KETOMAC CREAM. This will stop your condition flaring up while KETOMAC CREAM starts to work. If you have any queries about stopping your steroid lotion or cream, consult your doctor.

    References

    1. KD. Tripathi. Antifungal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page-791, 792.

    2. Hadeer Sinawe, Damian Casadesus. Ketoconazole. NIH National Library of Medicine. National Centre for Biotechnology Information. StatPearls [Internet]. June 2022. [Accessed 18th October 2024] https://www.ncbi.nlm.nih.gov/books/NBK559221/

    3. Choi FD, Juhasz MLW, Atanaskova Mesinkovska N. Topical ketoconazole: a systematic review of current dermatological applications and future developments. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. October 1987. [Accessed on 18th October 2024] https://pubmed.ncbi.nlm.nih.gov/30668185/

    4. Janssen Pharmaceutica NV. Health Products Regulatory Authority (HPRA). [Revised in July 2022] [Accessed on 18th October 2024] https://www.hpra.ie/img/uploaded/swedocuments/4bf3b755-f85e-41e5-916a-b7c9a7fc10d6.pdf

    5. Janssen Pharmaceutica NV. Electronic Medicines Compendium (EMC). [Revised in March 2021] [Accessed 18th October 2024] https://www.medicines.org.uk/emc/files/pil.970.pdf

    6. Palsons Derma. Novale scalp lotion (Ketoconazole 2%). [Accessed on 18th October 2024] https://www.palsonsderma.com/novale-scalp-lotion

    7. Praise Pharma. Esava ointment. (Ketoconazole 2%). [Accessed on 18th October 2024] http://www.praisepharma.com/products/anti-fungal_esava-ointment.html

    Useful Diagnostic Tests

    • Skin care package

    Author Details

    Written By Srilekha. R - B.Pharm
    Reviewed For Accuracy By Dr. Karthikeyan Rajagopal - M. Pharma, Ph.D (Pharmacology)
    Last updated on 14 Sep 2024 | 03:17 PM(IST)
    Lab updated