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Introduction About KETOGATE 4/3MG EYE DROPS
KETOGATE 4/3MG EYE DROPS is a combination of Gatifloxacin and Ketorolac which belongs to the group of medicines called Antibiotics and Non-steroidal anti-inflammatory drugs (NSAIDs) respectively. It is used to manage eye inflammation and/or infection following eye surgery.
KETOGATE 4/3MG EYE DROPS is for ophthalmic use only. Instil few drops of the medicine into the affected eye(s). Do not touch the tip of the dropper with your eye or other body surface to avoid contamination. If you wear soft contact lenses, remove the lens before applying KETOGATE 4/3MG EYE DROPS and wait for at least 15 minutes before reinsertion.
Before using KETOGATE 4/3MG EYE DROPS inform your doctor if you have diabetes, arthritis or bleeding problems. You must also inform your doctor if you have any eye infections as a precaution.
KETOGATE 4/3MG EYE DROPS is not recommended for use in pregnant women and in breastfeeding women unless considered necessary by the physician. The most common side effects of using KETOGATE 4/3MG EYE DROPS are blurred vision, eye irritation or burning sensation. Consult your doctor if any of these side effect worsens.
Uses Of KETOGATE 4/3MG EYE DROPS
- Manage and manages post-operative eye inflammation and infection
How KETOGATE 4/3MG EYE DROPS Works
KETOGATE 4/3MG EYE DROPS contains two medicines namely gatifloxacin and ketorolac. Gatifloxacin is an antibacterial agent. When applied topically on the eyes, it kills the susceptible bacteria that causes eye infection.
Ketorolac is a pain-relieving medicine. It blocks the release of certain chemicals in the body (such as prostaglandins) that causes eye pain, inflammation and swelling. Collectively, they act together and manages eye pain, inflammation and/or infection that can occur following eye surgeries.
How to use KETOGATE 4/3MG EYE DROPS
Use KETOGATE 4/3MG EYE DROPS as advised by your physician. It is for ophthalmic use only.
Wash your hands before application. Tilt your head slightly backwards and place the tip of the container close to your eyes. Gently pull your lower eyelid and instil few drops of the medicine as directed by your physician.
Close your eyes and gently press the inner corner of your eye for 2 minutes. Repeat the same for the other eye if required.
Do not touch the tip of the container with your eyes, eyelids or areas around your eyes or fingers, to avoid contamination. Apply applying KETOGATE 4/3MG EYE DROPS, leave a time gap of at least 5 minutes before applying other eye drops or ointment.
If you wear soft contact lenses, remove the lens before applying KETOGATE 4/3MG EYE DROPS and wait for at least 15 minutes before reinsertion. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition.
Side Effects Of KETOGATE 4/3MG EYE DROPS
Common
- burning and stinging of the eyes
- redness, itching and watering of eyes or eyelids
- eye discomfort
- eye pain or irritation
- blurred vision, headache
- changes in taste
Uncommon
- eye dryness
Rare
Stop using KETOGATE 4/3MG EYE DROPS and contact your doctor immediately if you experience any of the following side effects:
- severe eye pain, irritation and vision changes
How To Manage Side Effects
Burning or stinging of eyes:
Wash your eyes with plain cold water. Place an ice pack on your eye to ease the irritation. Avoid straining your eyes by looking at mobile phones, laptops or television. Wear protective eyeglasses while going outdoors.
Headache:
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Blurred vision:
Close your eyes and relax. Do not strain your eyes by looking at mobile phones, laptops, or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience blurred vision for a prolonged period.
Warning & Precautions
Pregnancy
KETOGATE 4/3MG EYE DROPS is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, inform your doctor before using it.
Breastfeeding
KETOGATE 4/3MG EYE DROPS is not recommended for use in breastfeeding women unless considered necessary by the physician. Therefore, inform your doctor before using it.
Driving and Using Machines
Do not drive or operate any machines if you experience blurred vision after using KETOGATE 4/3MG EYE DROPS. Wait, until your vision becomes clear.
Allergy
Do not use KETOGATE 4/3MG EYE DROPS if you are allergic to Gatifloxacin, Ketorolac or to any other NSAIDs (such as aspirin).
Lungs
KETOGATE 4/3MG EYE DROPS should be used with caution in patients who previously developed asthma while using any non-steroidal anti-inflammatory drugs. Therefore, consult your doctor before application.
Others
Before using KETOGATE 4/3MG EYE DROPS inform your doctor if you currently have or previously had:
- any bacterial or viral infections in the eye
- bleeding problems
- diabetes
- rheumatoid arthritis (joint pain)
- dry eye syndrome
- repeated eye surgery within a short period of time
Use in pediatrics:
KETOGATE 4/3MG EYE DROPS is generally not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before application.
Use in geriatrics:
KETOGATE 4/3MG EYE DROPS should be used with caution in elderly patients (aged 65 years and above). Therefore, consult your doctor before application.
Interactions
A. Drug-Drug interactions:
Before using KETOGATE 4/3MG EYE DROPS, inform your doctor if you are taking any medicines including prescription medicines, non-prescription medicines and herbal medicines.
Overdosage:
If you or anyone else accidentally used more KETOGATE 4/3MG EYE DROPS, rinse your eye with warm water. If still irritation persists, consult your doctor.
Synopsis
| Drug | : | Gatifloxacin, Ketorolac |
| Pharmacological Category | : | Fluroquinolones, Non-selective COX inhibitors |
| Therapeutic Indication | : | Prevents post operative eye infection and inflammation |
| Dosage Forms | : | Eye drops, Ophthalmic solution |
More Information
- Keep KETOGATE 4/3MG EYE DROPS out of reach of children
- Store KETOGATE 4/3MG EYE DROPS at room temperature
FAQs About KETOGATE 4/3MG EYE DROPS
Can the use of KETOGATE 4/3MG EYE DROPS cause blurred vision?
Yes. KETOGATE 4/3MG EYE DROPS may cause blurred vision after application in some individuals, although not everybody gets them. If your vision becomes blur, close your eyes for some time and rest. Do not strain your eyes by looking at mobile phones, laptops or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience blurred vision for a prolonged period.
Can I use other eye medicines while using KETOGATE 4/3MG EYE DROPS?
Avoid concomittant use of any eye medicines while using KETOGATE 4/3MG EYE DROPS without consulting your doctor.
How to use KETOGATE 4/3MG EYE DROPS?
Use KETOGATE 4/3MG EYE DROPS as advised by your physician. It is for ophthalmic use only. Instil few drops of the medicine into the affected eye(s). Close your eyes and press the corner of your eye with your finger for a minute. Repeat the same for the other eye if required.
What is the use of KETOGATE 4/3MG EYE DROPS?
KETOGATE 4/3MG EYE DROPS is a prescription medicine used to manage eye inflammation and/or infection following eye surgery.
How long does it take for [GBNKRYWORD] to work?
It may take around 10-15 minutes for KETOGATE 4/3MG EYE DROPS to start showing its effects. However, this period may vary from person-to-person depending upon the dose that is administered.
What are the side effects of KETOGATE 4/3MG EYE DROPS?
KETOGATE 4/3MG EYE DROPS is generally safe and well tolerated. It may cause blurred vision, eye irritation or burning sensation in some individuals. Contact your doctor if they trouble you.
Can I use KETOGATE 4/3MG EYE DROPS while wearing contact lenses?
If you wear soft contact lenses, remove the lens before applying KETOGATE 4/3MG EYE DROPS and wait for at least 15 minutes before reinsertion.
Can I stop using KETOGATE 4/3MG EYE DROPS without consulting my doctor?
Do not stop using KETOGATE 4/3MG EYE DROPS without consulting your doctor, as the symptoms may reappear once again. If you think that you are feeling better or if you wish to stop using KETOGATE 4/3MG EYE DROPS, contact your doctor for advice.
Can I drive or ride a bike after using KETOGATE 4/3MG EYE DROPS?
Do not drive if you experience blurred vision after using KETOGATE 4/3MG EYE DROPS.
What if I miss a dose of KETOGATE 4/3MG EYE DROPS?
If you missed a dose of KETOGATE 4/3MG EYE DROPS, apply it as soon as you remember. However, if it is time for next dose, skip the missed dose and use the regular dose. Do not use a double dose of KETOGATE 4/3MG EYE DROPS to compensate the missed dose.
How KETOGATE 4/3MG EYE DROPS works?
KETOGATE 4/3MG EYE DROPS blocks the release of certain chemicals in the body (such as prostaglandins) that causes eye pain, inflammation and swelling. It also kills the susceptible bacteria that causes eye infection. Therefore, it manages eye pain, inflammation and/or infection that occurs following eye surgeries.
References
1. KD. Tripathi. Autacoids and related drugs. Sulfonamides, Cotrimoxazole and Quinolones. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 202 & 714.
2. Clyde Schultz. Gatifloxacin Ophthalmic Solution for Treatment of Bacterial Conjunctivitis: Safety, Efficacy and Patient Perspective. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed central. July 2012. [Accessed on 9th December 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619660/
3. Kerry D Solomon, Eric D Donnenfeld, Michael Raizman, Helga P Sandoval, Katherine Stern, Amanda VanDenburgh, Amanda VanDenburgh, Janet K Cheetham and Rhett Schiffman. Safety and efficacy of ketorolac tromethamine 0.4% ophthalmic solution in post-photorefractive keratectomy patients. Journal of Cataract and Refractive Surgery. ScienceDirect.com. August 2004. [Accessed on 9th December 2022] https://www.researchgate.net/publication/8398695_Safety_and_efficacy_of_ketorolac_tromethamine_04_ophthalmic_solution_in_post-photorefractive_keratectomy_patients
4. Akorn. GATIFLOXACIN solution/ drops. Dailymed.com. [Revised in March 2022]. [Accessed on 9th December 2022] https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=14312de6-67d4-4de2-854c-ef764090dd83
5. Allergan Pharmaceuticals Ireland. Electronic Medicines Compendium (EMC). [Revised in February 2022]. [Accessed on 9th December 2022] https://www.medicines.org.uk/emc/files/pil.855.pdf
6. Allergan India Private Limited. Piramal Healthcare Limited. [Accessed on 9th December 2022] https://allergan-web-cdn-prod.azureedge.net/allerganindia/allerganindia/media/allergan-india/products/ketomar.pdf
7. Central Drugs Standard Control Organization. Gatifloxacin 0.3% + Ketorolac Tramthamine 0.4% eye Drop. July 2008. [Accessed on 9th November 2022] https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadApprovalNewDrugs/dciApprovedfdc.pdf
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