Jointace DN Tablet 15'S

Introduction About JOINTACE DN TABLET

JOINTACE DN TABLET is a combination of Diacerein, Glucosamine, and Methyl Sulfonyl Methane which belongs to the group of medicines called proteoglycan synthesis stimulators and nutritional supplements, respectively. It is used in the management of osteoarthritis. Osteoarthritis is a condition that causes pain, swelling, and stiffness in the joints of the hands, knees, hips, and spine.

In osteoarthritis, the cartilage between the bones in the joint breaks down, which in turn causes the affected bones to slowly get bigger. The joint cartilage often breaks down because of mechanical stress or biochemical changes within the body, causing the bone underneath to fail.

JOINTACE DN TABLET is not recommended for use in patients with liver problems. Before taking JOINTACE DN TABLET, inform your doctor if you have suffered from impaired glucose tolerance, kidney problems, heart disease, or asthma. JOINTACE DN TABLET is generally not recommended for use among women who are pregnant or breastfeeding.

JOINTACE DN TABLET is not recommended for use in children and adolescents (18 years and below). JOINTACE DN TABLET is to be taken with caution by elderly patients. The most common side effects of taking JOINTACE DN TABLET are nausea, diarrhea, constipation, indigestion, heartburn, and urine discoloration. Ask your doctor for advice if any of these side effects worsen or don’t improve.

Uses Of JOINTACE DN TABLET

• To manage osteoarthritis

How JOINTACE DN TABLET Works

JOINTACE DN TABLET is a combination of Diacerein, Glucosamine, and Methyl Sulfonyl Methane. Diacerein and glucosamine are proteoglycan synthesis stimulators that facilitate the formation of cartilage, which is an important structural component of the body. Methyl Sulfonyl Methane is a nutritional supplement that functions by lessening pain and swelling by reducing inflammation.

How to use JOINTACE DN TABLET

Take JOINTACE DN TABLET as advised by your physician. Swallow the medicine with enough water. Do not crush or chew the medicine. Your physician will decide the correct dose and duration of JOINTACE DN TABLET for you depending on your age, body weight, and disease condition.

Side Effects Of JOINTACE DN TABLET

How To Manage Side Effects

Constipation

Eat more fiber-rich foods, such as fresh fruits, vegetables, and cereals, and drink more water. Exercise more regularly.

Diarrhea

Drink more fluids like water, squash, or fruit juice to keep yourself hydrated. Do not consume any medicine for diarrhea by yourself without consulting your doctor. If the symptom doesn’t improve, consult with your doctor.

Nausea And Vomiting

Take this medicine with, or just after, meals. Stick to simple meals. Avoid eating rich or spicy food. If the symptoms don’t improve, consult with your doctor.

Warning & Precautions

Pregnancy

Monitoring required

JOINTACE DN TABLET is not recommended for use by pregnant women unless considered necessary. Consult your physician before taking it.

Breastfeeding

Contraindicated

JOINTACE DN TABLET is not recommended for use in breastfeeding women as small traces may pass through the mother’s milk. Consult your physician before taking it.

Driving and Using Machines

Use with Caution

Dizziness has been reported during management with JOINTACE DN TABLET and may affect the ability to drive and use machines. Consult your physician before taking JOINTACE DN TABLET.

Alcohol

Use with Caution

JOINTACE DN TABLET should be used with caution when drinking any alcoholic beverage.

Kidney

Use with Caution

JOINTACE DN TABLET should be taken with caution in patients with kidney problems. Consult your doctor for advice.

Liver

Use with Caution

JOINTACE DN TABLET should be taken with caution in patients with liver problems. Consult your doctor for advice.

Allergy

Contraindicated

Do not take JOINTACE DN TABLET if you are allergic to Diacerein, Glucosamine, Methyl Sulfonyl Methane, or any of the other ingredients in this medicine.

Heart Disease

Use with Caution

JOINTACE DN TABLET should be taken with caution in patients with heart problems. Consult your doctor for advice.

Use In Pediatrics

Contraindicated

JOINTACE DN TABLET is not recommended for use in children and adolescents (18 years and below). Consult your physician for advice before taking JOINTACE DN TABLET.

Use In Geriatrics

Use with Caution

JOINTACE DN TABLET should be taken with caution in elderly patients. Consult your doctor for advice before taking JOINTACE DN TABLET.

Interactions

A. Drug-Drug Interactions:

Inform your physician if you are taking any of the following drugs before taking JOINTACE DN TABLET:

• medicine used to thin the blood (Ex. warfarin)
• medicine used to manage diabetes (Ex. metformin, insulin)
• medicine used to manage bacterial infections (Ex. tetracyclines)

Overdosage:

If you or anyone else accidentally takes too much of JOINTACE DN TABLET, consult your doctor immediately or visit the nearby hospital. The symptoms of overdosage may include headache, dizziness, disorientation, joint pain, feeling sick (nausea) or being sick (vomiting), diarrhea, or constipation.

Synopsis

More Information

• Keep JOINTACE DN TABLET out of reach of children
• Store at room temperature in a cool, dry place

FAQs About JOINTACE DN TABLET

Q: What precautions are to be taken if I take too much JOINTACE DN TABLET?

A: If you or anyone else accidentally takes too much JOINTACE DN TABLET, consult your doctor immediately or visit the nearby hospital. The symptoms of an overdose of JOINTACE DN TABLET may include headache, dizziness, disorientation, joint pain, feeling sick (nausea) or being sick (vomiting), diarrhea, or constipation.

Q: Is JOINTACE DN TABLET safe to use with children and the elderly?

A: JOINTACE DN TABLET is not recommended for use in children (age 18 years and below), and it should be used with caution in elderly patients. Before taking JOINTACE DN TABLET, please consult your physician for advice.

Q: Can JOINTACE DN TABLET be given to pregnant and breastfeeding women?

A: JOINTACE DN TABLET should not be used in pregnant or breastfeeding women unless necessary. Consult your physician before taking it.

Q: How does JOINTACE DN TABLET act?

A: JOINTACE DN TABLET is a diacerein, glucosamine, and methyl sulfonyl methane combination. Diacerein and glucosamine are proteoglycan synthesis stimulators that facilitate the formation of cartilage, which is an important structural component of the body. Methyl Sulfonyl Methane is a nutritional supplement that functions by lessening pain and swelling by reducing inflammation.

Q: What are the common side effects of JOINTACE DN TABLET?

A: The most common side effects of taking JOINTACE DN TABLET are nausea, diarrhea, constipation, indigestion, heartburn, and urine discoloration. Ask your doctor for advice if any of these side effects worsen or don’t improve.

References

1. Karel Pavelka, Olivier Bruyère, Cyrus Cooper, John A. Kanis, Burkhard F. Leeb, Emmanuel Maheu, Johanne Martel-Pelletier, Jordi Monfort, Jean-Pierre Pelletier, René Rizzoli, and Jean-Yves Reginster. Diacerein: Benefits, Risks and Place in the Management of Osteoarthritis. An Opinion-Based Report from the ESCEO. Journal of Drugs and Aging. February 2016. [Accessed on 5th February 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756045/

2. Toru Ogata, Yuki Ideno, Masami Akai, Atsushi Seichi, Hiroshi Hagino, Tsutomu Iwaya, Toru Doi, Keiko Yamada, Ai-Zhen Chen, Yingzi Li, and Kunihiko Hayashi. Effects of glucosamine in patients with osteoarthritis of the knee: a systematic review and meta-analysis. Journal of Clinical Rheumatology. April 2018. [Accessed on 5th February 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097075/

3. Mariè van der Merwe and Richard J. Bloomer. The Influence of Methylsulfonylmethane on Inflammation-Associated Cytokine Release before and following Strenuous Exercise. Journal of Sports Medicine. October 2016. [Accessed on 5th February 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097813/

4. Leeford. Diacerein, Glucosamine, and Methyl Sulfonyl Methane. [Accessed on 5th February 2024] https://www.leeford.in/product/941/dincerin-plus

5. Saturn Formulations Pvt. Ltd. Diacerein, Glucosamine, and Methyl Sulfonyl Methane. [Accessed on 5th February 2024] https://saturnformulations.in/product/diacerein-glucosamine-sulphate-potassium/

6. Alpha Drugs. Diacerein, Glucosamine, and Methyl Sulfonyl Methane. [Accessed on 5th February 2024] https://www.alphadrug.in/product/walksafe

7. FMC Pharma Ltd. [Revised on May 2016] [Accessed on 5th February 2024] https://www.hpra.ie/img/uploaded/swedocuments/2171814.PA1521_003_002.cb4ba0a2-1887-4c40-afe6-e19cea656342.000001750mg%20PIL%20.160824.pdf

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Author Details

Written By Dr. N. Sai Swaroop - Pharm.D

Reviewed For Accuracy By Dr. Srikar Modepu - MBBS, MD (Diabetology)

Last updated on 06 Feb 2024 | 04:49 PM(IST)