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Introduction About JANUVIA 25MG TABLET
JANUVIA 25MG TABLET is used to manage type 2 diabetes alone or along with other anti-diabetic medicines, diet, and exercise. It contains Sitagliptin which belongs to the group of medicines called Anti-diabetic drugs.
Before taking JANUVIA 25MG TABLET, inform your doctor if you have any disease of the pancreas, gallstones, alcohol dependence, very high levels of fat in your blood, type 1 diabetes, diabetic ketoacidosis, or any kidney or heart problems.
JANUVIA 25MG TABLET is not recommended for use in children and adolescents under 18 years of age. The most common side effects are low blood sugar, headache, upper respiratory infection, stuffy or runny nose, sore throat, osteoarthritis, and arm or leg pain. Contact your doctor if any of the symptoms worsen.
Uses Of JANUVIA 25MG TABLET
- Used to manage type 2 diabetes
How JANUVIA 25MG TABLET Works
JANUVIA 25MG TABLET works by slowing down the inactivation of gut hormones released after eating the meals. This kind of action increases the secretion of insulin and decreases glucagon release (a hormone that raises blood glucose levels), resulting in an overall increase in blood glucose control.
How to use JANUVIA 25MG TABLET
- Take JANUVIA 25MG TABLET as advised by your physician
- Swallow the medicine with a glass of water. Do not crush or chew the medicine
- Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition
Side Effects Of JANUVIA 25MG TABLET
Common side effects of JANUVIA 25MG TABLET:
- signs of low blood sugar (drowsiness, irritability, hunger, dizziness, confusion, sweating, weakness, and fast heartbeat)
- stuffy or runny nose, sore throat
- joint pain
- flatulence, stomach pain, diarrhea, constipation
Stop taking JANUVIA 25MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- signs of pancreatitis (severe and continuous pain in the stomach area that might reach through your back with or without nausea and vomiting)
- signs of a serious allergic reaction (rash, hives, blistering or peeling of the skin, and swelling of the face, lips, tongue, and throat that may cause trouble breathing or difficulty swallowing)
- bullous pemphigoid symptoms, such as skin blistering
Warning & Precautions
Pregnancy
Consult your doctorIt is not known if JANUVIA 25MG TABLET will harm unborn baby. If you are pregnant, talk with your doctor about the best way to control your blood sugar while you are pregnant.
Breastfeeding
Consult your doctorIt is not known if JANUVIA 25MG TABLET will pass into breast milk. Talk with your doctor about the best way to feed the baby if you are taking the medicine.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel dizzy or drowsy after taking JANUVIA 25MG TABLET.
Alcohol
Consult your doctorBefore taking JANUVIA 25MG TABLET, inform your doctor if you have or had alcohol dependence.
Kidney
Use with CautionJANUVIA 25MG TABLET should be used with caution in patients with kidney problems.
Allergy
ContraindicatedDo not take JANUVIA 25MG TABLET if you are allergic to Sitagliptin or any other ingredients of this medicine.
Use In Pediatrics
ContraindicatedJANUVIA 25MG TABLET is not recommended for use in children and adolescents under 18 years of age.
Use In Geriatrics
Use with CautionJANUVIA 25MG TABLET should be used with caution in elderly patients.
Others
Before taking JANUVIA 25MG TABLET, inform your doctor if you have or had:
- inflammation of pancreas
- gallstones
- excessive levels of fat in blood
- type 1 diabetes
- diabetic ketoacidosis
Interactions
A. Drug-Drug interactions:
Before taking JANUVIA 25MG TABLET, inform your doctor if you are taking any of the following medicines:
- Antidiabetics (Ex. insulin, glimepiride, metformin)
- Cardiac glycosides (Ex. digoxin)
Overdosage:
If you or anyone else accidentally take too much of JANUVIA 25MG TABLET, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Sitagliptin |
| Pharmacological Category | : | Dipeptidyl Peptidase-4 Inhibitors |
| Therapeutic Indication | : | Type-2 Diabetes mellitus |
| Dosage Forms | : | Tablet |
More Information
FAQs About JANUVIA 25MG TABLET
Q: What is JANUVIA 25MG TABLET used for?
A: JANUVIA 25MG TABLET is used in adults to manage type 2 diabetes alone or along with other anti-diabetic medicines, diet, and exercise.
Q: Can JANUVIA 25MG TABLET cause heart failure?
A: Heart failure is seen in patients during management with JANUVIA 25MG TABLET. You are at greater risk of heart failure if you previously had any heart disease like heart failure or kidney disease. You must talk to your doctor immediately or go to the nearest hospital if this happens to you.
Q: Can JANUVIA 25MG TABLET be used in infants?
A: No, JANUVIA 25MG TABLET is used for adults and not recommended for children and adolescents under 18 years of age. It is not effective in children and adolescents between the ages of 10 and 17 years.
Q: What if I miss a dose of JANUVIA 25MG TABLET?
A: If you miss a dose of JANUVIA 25MG TABLET, take it as soon as you remember. However, omit the missed dose if it is almost time for the next dose. Do not take the medicine twice to make up for the missed dose.
Q: Can JANUVIA 25MG TABLET cause hypoglycemia?
A: Yes, JANUVIA 25MG TABLET may cause hypoglycemia (low blood sugar levels). In such cases, have fruit juice, glucose tablets or gel, soft drinks, honey, or sugary candy. Check your blood sugar after 10 minutes. If not at the optimum level, take another sugary snack or drink and check the blood sugar again.
Q: Can I stop taking JANUVIA 25MG TABLET?
A: Do not stop taking JANUVIA 25MG TABLET without consulting your doctor. Take it as long as advised by your doctor to keep your sugar levels under control. If you have any more doubts regarding the use of JANUVIA 25MG TABLET, ask your doctor.
Q: Is JANUVIA 25MG TABLET safe during pregnancy?
A: It is not known if JANUVIA 25MG TABLET will harm unborn baby. If you are pregnant, talk with your doctor about the best way to control your blood sugar while you are pregnant.
Q: Who should not take JANUVIA 25MG TABLET?
A: Do not take JANUVIA 25MG TABLET if you are allergic to Sitagliptin or any other ingredients of this medicine.
Q: What precautions must be taken while using JANUVIA 25MG TABLET?
A: Before taking JANUVIA 25MG TABLET, inform your doctor if you have inflammation of your pancreas, gallstones, excessive levels of fat in your blood, type 1 diabetes, diabetic ketoacidosis, and kidney problems.
Q: What should I avoid while taking JANUVIA 25MG TABLET?
A: Avoid drinking alcohol while taking JANUVIA 25MG TABLET, as it may increase the risk of low blood sugar levels.
References
1. Joseph T. DiPiro, Robert L. Talbert, Gary C. Yee, Gary R. Matzke, Barbara G. Wells, and L. Michael Posey. Diabetes Mellitus. Pharmacotherapy: A Pathophysiologic Approach. Eighth edition. Page-1263, 1264.
2. Plosker GL. Sitagliptin: A review of its use in patients with type 2 diabetes mellitus. NIH, National Library of Medicine, National Center for Biotechnology Information Pubmed.gov. February 2014. [Accessed on 28th August 2024] click here
3. PubChem Compound Summary for CID 4369359, Sitagliptin. National Center for Biotechnology Information. May 2022. [Accessed on 28th August 2024] click here
4. Organon Pharma (UK) Limited. Electronic Medicines Compendium (EMC). [Revised in November 2021] [Accessed on 28th August 2024] click here
5. Merck Sharp & Dohme Corp. Sitagliptin. [Revised in December 2020] [Accessed on 28th August 2024] click here
6. Merck Sharp & Dohme Corp., Sitagliptin. [Revised in December 2021] [Accessed on 28th August 2024] click here
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