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Uth Healthcare Ltd

JANISHA Tablet 10's

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    Introduction About JANISHA TABLET

    JANISHA TABLET is used as an adjunct to diet and exercise to control elevated blood sugar levels in adult patients with type II diabetes mellitus. It contains a medicine called Teneligliptin which lowers blood glucose levels by blocking the actions of an enzyme called dipeptidyl peptidase (DPP)-4 that regulates the secretion of insulin in the body.

    During therapy with JANISHA TABLET, your doctor might ask you to make certain lifestyle changes such as following a healthy diet, regular physical exercise, and quitting alcohol consumption.

    Before taking JANISHA TABLET, inform your doctor if you have any liver or heart problems. You must also inform your doctor if you have hormonal problems, stomach problems (surgery in the gut) or if you are malnourished, starved, on an irregular diet.

    JANISHA TABLET is not suitable for use in patients with type I diabetes mellitus. Consult your doctor before taking JANISHA TABLET if you are pregnant or planning to become pregnant. 

    One of the most common side effects of taking JANISHA TABLET is hypoglycemia (blood sugar levels) which can be identified by symptoms such as increased hunger, sweating, shakiness, weakness, or an irregular heartbeat. To avoid this, your doctor will periodically monitor your blood sugar levels and adjust the dose of JANISHA TABLET accordingly.

    You can also carry a sugary snack (such as biscuits, glucose drinks or sweet candies) along with you as a precaution and have them immediately if you experience any signs of hypokalemia. However, consult your doctor if there is no improvement in your condition. Other common side effects of taking JANISHA TABLET are headache, dizziness, and constipation.

    Uses Of JANISHA TABLET

    • It is used in adjunct to diet and exercise to manage type II diabetes mellitus in adults

    How JANISHA TABLET Works

    JANISHA TABLET effectively controls blood glucose levels in patients with type II diabetes mellitus. It contains teneligliptin which is a dipeptidyl peptidase (DPP)-4 inhibitor. It lowers blood glucose levels by blocking the actions of an enzyme called DPP-4 that regulates the secretion of insulin in the body. As a result, it improves insulin production and helps in the digestion of circulating blood glucose. It can also regulate blood sugar post meal by controlling glucagon secretion.

    How to use JANISHA TABLET

    Take JANISHA TABLET as advised by your physician.

    Swallow the medicine with a glass of water. Do not crush or chew the medicine.

    JANISHA TABLET should be taken preferably after meals.

    Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

    Side Effects Of JANISHA TABLET

    Like all medications, this medicine may cause side effects, although they do not occur in everyone.

    Common Side Effects of JANISHA TABLET:

    • hypoglycemia (low blood sugar)
    • dizziness
    • headache
    • constipation, diarrhoea
    • fever

    How To Manage Side Effects

    Constipation

    Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if this side effect bothers you.

    Diarrhea

    Hydrate yourself by drinking plenty of fluids, such as water or fruit juices. Consuming ORS can also be beneficial. Do not self-manage diarrhea on your own. Consult your doctor if your diarrhea becomes uncontrollable.

    Hypoglycemia

    Have foods rich in sugars such as fruit juices, glucose drinks, candies, honey, or biscuits. Check your blood sugar after 10 minutes. If not gained optimum level, take another sugary snack, or a drink, and check the blood sugar again. consult your doctor if there is no improvement in your condition.

    Warning & Precautions

    Pregnancy

    Monitoring required

    JANISHA TABLET should be used in pregnant women only if prescribed by the physician. Your doctor may prescribe JANISHA TABLET for you after evaluating the risks and benefit ratio. Therefore, consult your doctor before taking it.

    Breastfeeding

    Contraindicated

    Breast-feeding should be stopped during management with JANISHA TABLET. However, consult your doctor before taking it.

    Driving and Using Machines

    Use with Caution

    Do not drive or operate any machines if you feel dizzy after taking JANISHA TABLET.

    Alcohol

    Consult your doctor

    Avoid consumption of alcohol while taking JANISHA TABLET as it may increase the risks of side effects.

    Liver

    Use with Caution

    JANISHA TABLET should be used with caution in patients with severe liver diseases. Therefore, consult your doctor before taking it.

    Allergy

    Contraindicated

    Do not take JANISHA TABLET if you are allergic to Teneligliptin.

    Heart Disease

    Use with Caution

    JANISHA TABLET should be used with caution in patients with heart problems (like heart failure or slow heartbeat). Therefore, consult your doctor before taking it.

    Use In Pediatrics

    Consult your doctor

    There is no proper information regarding the use of JANISHA TABLET in children and in adolescents (below 18 years). Therefore, consult your doctor before taking it.

    Use In Geriatrics

    Use with Caution

    JANISHA TABLET should be used with caution in elderly patients. Therefore, consult your doctor before taking it. Proper dose adjustments and careful monitoring are required in such patients.

    Others

    JANISHA TABLET is not recommended for use if you:

    • have severe ketosis (increased levels of ketone bodies in the blood)
    • have diabetic coma or precoma
    • have type I diabetes mellitus
    • have serious traumatic injury

    Before taking JANISHA TABLET, inform your doctor if you:

    • have pituitary insufficiency or adrenal insufficiency
    • are malnourished, starved, on an irregular diet, or feeling weak
    • perform extreme muscle exercises
    • have a history of abdominal operation or intestinal obstruction
    • have hypokalaemia (low blood potassium levels)

    Interactions

    A. Drug-Drug interactions:

    Before taking JANISHA TABLET, inform your doctor if you are taking any of the following medicines such as:

    • other medicines used to manage diabetes (such as glimepiride, exenatide, acarbose, metformin, pioglitazone, repaglinide, empagliflozin or insulin)
    • beta blockers (medicines used to manage high blood pressure) Ex. atenolol, propranolol
    • salicylic acid (a medicine used to manage skin problems like acne)
    • medicines used to manage depression (Ex. phenelzine, selegiline)
    • adrenaline (a medicine used to manage shock caused by allergic reactions or collapse)
    • thyroid hormones (used to manage thyroid deficiency) Ex. levothyroxine, liothyronine
    • medicines used to manage irregular heartbeats (Ex. quinidine, procainamide, amiodarone, sotalol, etc.)

    Overdosage:

    If you or anyone else accidentally took more JANISHA TABLET, consult your doctor immediately or visit the nearby hospital.

    Synopsis

    Drug :   Teneligliptin
    Pharmacological Category :   Dipeptidyl Peptidase-4 Inhibitors
    Therapeutic Indication :   Type II Diabetes mellitus                     
    Dosage Forms :   Tablet

    More Information

    Storage

    • Keep JANISHA TABLET out of reach of children
    • Store JANISHA TABLET at room temperature

    FAQs About JANISHA TABLET

    Q: What is JANISHA TABLET used for?

    A: JANISHA TABLET contains Teneligliptin which is used to manage type II diabetes (high blood sugar levels) in adults, that cannot be controlled by diet and exercise alone. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

    Q: Is JANISHA TABLET safe to use in pregnancy?

    A: JANISHA TABLET should be used in pregnant women only if prescribed by the physician. Your doctor may prescribe JANISHA TABLET for you after evaluating the risks and benefit ratio. Therefore, consult your doctor before taking it.

    Q: What precautions do I need to follow while taking JANISHA TABLET?

    A: Before taking JANISHA TABLET, inform your doctor if you have any liver or heart problems. You must also inform your doctor if you have hormonal problems, stomach problems (surgery in the gut) or if you are malnourished. JANISHA TABLET is not suitable for use in patients with type I diabetes mellitus. Consult your doctor before taking JANISHA TABLET if you are pregnant or planning to become pregnant. During therapy with JANISHA TABLET, follow the diet and lifestyle changes instructed by your doctor. Always carry a sugary snack (such as biscuits, glucose drinks or sweet candies) along with you as a precaution and have them immediately if you experience any signs of hypokalemia.

    Q: Can I take medication for high blood pressure along with JANISHA TABLET?

    A: No. It is not advisable to take medicines to control blood pressure while taking JANISHA TABLET without consulting your doctor. Therefore, consult your doctor before taking any antihypertensive such as beta blockers (Ex. atenolol, propranolol) along with JANISHA TABLET as they have known interactions with JANISHA TABLET.

    Q: What should I do if I experience low blood sugar after taking JANISHA TABLET?

    A: Low blood sugar is a common side effect of taking JANISHA TABLET. Try to have sugar rich food items such as fruit juice, glucose tablets or gel, soft drinks, honey, or sugary candy. Check your blood sugar after 10 minutes. If not gained optimum level, take another sugary snack, or drink, and check the blood sugar again. In case of persistent low blood sugar levels, consult your doctor immediately.

    Q: Can JANISHA TABLET cause dizziness?

    A: Yes. Dizziness is a common side effect of using JANISHA TABLET. In case you experience dizziness, lie down until it passes, then get up slowly and carefully. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, and alcohol. Do not drive or use machinery to avoid accidents. Consult your doctor if you experience dizziness continuousy for a long time after taking JANISHA TABLET.

    Q: Can JANISHA TABLET be taken with insulin?

    A: Co-administration of JANISHA TABLET with insulin is considered risky as they are increased chances of hypoglycemia (decreased blood sugar levels). Consult your doctor before taking it.

    Q: How to take JANISHA TABLET?

    A: You must take JANISHA TABLET as advised by your physician. Try to take this medicine preferably after meals and swallow it with a glass of water. Do not crush or chew the medicine.

    Q: How much JANISHA TABLET should I take?

    A: JANISHA TABLET should be used only under medical supervision. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body condition and severity of the disease condition.

    Q: Can JANISHA TABLET cause constipation?

    A: Yes. Constipation is a common side effect of using JANISHA TABLET. Eat plenty of fiber rich foods such as fresh fruits, vegetables, cereals as well as drink plenty of water and exercise more regularly when taking this medicine. Contact your doctor if you experience constipation for a long time.

    References

    1. Joseph T. DiPiro, Robert L. Talbert, Gary C. Yee, Gary R. Matzke, Barbara G. Wells, L. Michael Posey. Diabetes Mellitus. Pharmacotherapy- A Pathophysiologic Approach. Eighth edition. Page- 1263, 1264.

    2. Mitra, A., & Ray, S. Evaluation of the Safety and Efficacy of Teneligliptin at a Higher Dose in Indian Type 2 Diabetes Patients: A Retrospective Analysis. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. January 2020. [Accessed on 19th April 2022] click here

    3. Torrent Pharmaceutical Ltd. Teneligliptin. [Revised in April 2021] [Accessed on 19th April 2022] click here

    4. Mitsubishi Tanabe Pharma Factory Ltd. Teneligliptin. [Revised in April 2020] [Accessed on 19th April 2022] click here

    Author Details

    Written By Srilekha. R - B.Pharm
    Reviewed For Accuracy By Dr. Jaya Prabakaran - MBBS, MD (Diabetology and Family Medicine)
    Last updated on 27 Nov 2024 | 04:16 PM(IST)
    Lab updated