JALRA 50mg Tablet 15's

Introduction About JALRA 50MG TABLET

JALRA 50mg Tablet contains Vildagliptin, an anti-diabetic medicine used in adults with type 2 diabetes mellitus when diet and exercise alone are not enough to manage blood sugar levels that works by improving the body’s natural response to glucose, supporting insulin release after meals, and lowering excess sugar production in the liver. 

JALRA 50mg Tablet is advised along with a healthy diet plan and regular physical activity to help maintain stable blood sugar control, which supports long-term health and reduces the risk of diabetes related complications such as kidney and eye problems. It can be taken with or without food. The dose will depend on your condition and blood sugar levels. Use it strictly as advised by your doctor.

Take JALRA 50mg Tablet regularly at the same time each day for best results. Do not discontinue the medicine without your doctor’s advice. Along with this tablet, it is important to follow the diet plan and exercise routine recommended by your doctor. Maintaining a healthy lifestyle plays a major role in keeping your blood sugar under control.

The most common side effects of JALRA 50mg Tablet include low blood sugar, tremors, headache, constipation, dizziness, fatigue, nausea, vomiting, and joint pain. Be aware of the signs of low blood sugar such as light headedness, sweating, fainting, dizziness, and dry mouth. Keeping sugar or glucose candies with you can help manage these symptoms if they occur. Consult your doctor if any side effects continue or cause concern.

Before taking JALRA 50mg Tablet, inform your doctor if you have a history of kidney problems, heart conditions, or pancreas-related disorders. Pregnant and breastfeeding women should seek medical advice before starting this medicine. Let your doctor know about all the other medicines you are taking, as some may affect how JALRA works. Limit alcohol consumption while on this tablet since it can increase the chances of low blood sugar. Your doctor may also recommend regular tests such as kidney function and blood glucose levels to monitor your progress.

Uses Of JALRA 50MG TABLET

• Used in adults with type 2 diabetes mellitus
• Recommended when diet and exercise alone are insufficient to control blood sugar
• Helps in improving the body’s natural response to glucose
• Supports insulin release after meals
• Reduces excess sugar production in the liver

Benefits of JALRA 50MG TABLET

1. Supports Blood Sugar Control: JALRA 50mg Tablet helps manage blood glucose levels in adults with type 2 diabetes mellitus when diet and exercise alone are not sufficient.
2. Enhances Natural Insulin Response: This medicine improves the body’s response to glucose by supporting insulin release after meals.
3. Reduces Excess Liver Sugar Production: The active ingredient vildagliptin lowers extra glucose output from the liver, contributing to stable blood sugar balance.
4. Can Be Combined with Other Anti-Diabetic Medicines: JALRA may be used alone or together with other diabetes medicines for improved blood sugar management.
5. Supports Long-Term Metabolic Health: By maintaining better glucose control, it helps reduce the chances of diabetes-related health complications over time.

How JALRA 50MG TABLET Works

How JALRA 50mg Tablet Works in Blood Sugar Control

JALRA 50mg Tablet contains vildagliptin, which supports blood sugar management by improving the body’s natural response to glucose. It helps the pancreas release insulin when blood sugar is high and reduces the release of glucagon, a hormone that increases blood sugar levels.

Mechanism of Action: Role of Vildagliptin as a DPP-4 Inhibitor

Vildagliptin works by blocking the enzyme DPP-4 that breaks down incretin hormones. These hormones, released after meals, stimulate insulin secretion and help balance blood sugar. By inhibiting DPP-4, vildagliptin increases the levels and action of incretins, helping the body regulate glucose more effectively.

JALRA and Incretin Hormones: Supporting Insulin Release

JALRA boosts incretin hormones such as GLP-1 and GIP, which signal the pancreas to release insulin in response to meals. This enhanced insulin release helps lower blood sugar after eating and supports overall glucose control.

Effects of JALRA on Liver Glucose Production and Glucagon Levels

JALRA reduces glucose production by the liver by lowering glucagon, a hormone that raises blood sugar. This helps decrease excess glucose in the blood, contributing to better blood sugar balance.

Why JALRA Works Only When Blood Sugar is Elevated

JALRA’s action depends on blood sugar levels, it helps increase insulin release only when blood glucose is high. This glucose-dependent effect lowers the risk of low blood sugar (hypoglycemia) when levels are normal or low.

Understanding JALRA’s Role in Type 2 Diabetes Management

JALRA supports adults with type 2 diabetes in managing blood sugar levels, especially when combined with a healthy diet and regular exercise. Its mechanism helps maintain better sugar control without causing weight gain or frequent low blood sugar episodes.

How to use JALRA 50MG TABLET

Recommended Dosage for JALRA 50mg Tablet

• The usual dose is one tablet twice daily (50 mg in the morning and 50 mg in the evening), totalling 100 mg per day when used alone or with other diabetes medicines like metformin or insulin.
• When combined with sulfonylureas, the dose is typically 50 mg once daily in the morning.
• Dosages higher than 100 mg per day are not recommended.

How to Take JALRA 50mg Tablet Safely

• Take JALRA regularly at the same time each day for consistent blood sugar control.
• Swallow the tablet whole with water; do not chew, crush, or break it.
• Follow your doctor's instructions carefully and do not stop the medicine without medical advice.

Administration Guidelines: With or Without Food?

• JALRA can be taken with or without food according to your convenience or doctor’s advice.
• Taking it with meals may help reduce any stomach discomfort.

Dosage Adjustments for Kidney or Liver Conditions

• Patients with moderate or severe kidney problems should take 50 mg once daily instead of twice daily.
• Liver function should be checked regularly as JALRA may affect liver enzymes, consult your doctor for dose adjustments if liver issues arise.

What to Do if You Miss a Dose of JALRA

• Take the missed dose as soon as you remember on the same day.
• Do not take a double dose on the same day to make up for the missed one.
• If it is almost time for the next dose, skip the missed dose and continue as usual.

Duration of Use and Monitoring During JALRA Therapy

• Continue JALRA as advised by your doctor to maintain stable blood sugar levels.
• Regular blood sugar and kidney function tests may be recommended to monitor therapy effectiveness and safety.
• Report any unusual symptoms or side effects to your healthcare provider promptly.

Combining JALRA with Other Diabetes Medicines

• JALRA can be used alone or in combination with other diabetes medicines like metformin, sulfonylureas, thiazolidinediones, or insulin for better blood sugar management.
• When used with sulfonylureas, dose adjustments may be necessary to reduce the risk of low blood sugar.
• Always inform your doctor about all medicines you are taking to avoid interactions.

Side Effects Of JALRA 50MG TABLET

Common side effects of Jalra 50mg Tablet:

• Low blood sugar
• Tremors
• Headache
• Constipation
• Dizziness
• Fatigue
• Nausea, vomiting
• Joint pain

When to consult your doctor?

• Signs of low blood sugar (hypoglycemia) such as severe dizziness, sweating, trembling, hunger, fast heartbeat, confusion, or fainting
• Symptoms of liver problems including yellowing of skin or eyes (jaundice), dark urine, loss of appetite, and abdominal pain
• Signs of pancreatitis such as severe and persistent stomach pain with nausea and vomiting
• Signs of allergic reactions such as swelling of the face, lips, tongue, or throat causing difficulty in breathing or swallowing
• Signs of serious muscle or blood problems such as unusual muscle pain or weakness, fever, or persistent tiredness
• Signs of lactic acidosis such as difficulty in breathing, rapid or deep breathing, feeling faint, or severe fatigue

How To Manage Side Effects

Dizziness Or Drowsiness

• Sit or Lie Down: If you feel dizzy, sit down, or lie down immediately to reduce falling. Keep your head still and close your eyes if needed.
• Hydrate: Dehydration can cause dizziness, so drink water or electrolyte-replenishing drinks like sports drinks.
• Avoid Sudden Movements: When standing or sitting, do so slowly to avoid triggering dizziness. Take your time when getting up.
• Eat Small, Regular Meals: Low blood sugar can cause dizziness, so eat small meals throughout the day and avoid skipping meals.
• Fresh Air: Sometimes dizziness can be alleviated by taking slow, deep breaths in a well-ventilated area.

Headache

• Stay Hydrated: Drink plenty of water throughout the day to help ease headache symptoms.
• Rest in a Quiet Environment: Minimize noise and bright lights by resting in a calm, dark room.
• Use Over-the-Counter Pain Relief: Consult your doctor about using mild pain relievers like acetaminophen to alleviate headaches.
• Avoid Stressful Activities: Limit activities that increase stress or physical exertion when experiencing headaches.
• Seek Medical Advice: Contact your healthcare provider if headaches become severe, persistent, or are accompanied by other symptoms.

Nausea And Vomiting

• Stay Hydrated: Sip fluids slowly, such as water, ginger tea, or clear soups to support hydration and reduce discomfort.
• Eat Small, Bland Meals: Choose light foods like crackers, toast, or plain rice to minimize stomach irritation.
• Avoid Strong Odors and Spicy Foods: These can worsen feelings of nausea and should be limited during symptoms.
• Rest and Relaxation: Rest in a comfortable position and avoid sudden movements to calm the digestive system.
• Seek Medical Advice: Consult a healthcare provider promptly if nausea is severe, persistent, or accompanied by vomiting.

Warning & Precautions

Pregnancy

Contraindicated

JALRA 50mg Tablet is not recommended for use during pregnancy. Women who are pregnant or planning to become pregnant should consult their doctor before taking this medicine.

Breastfeeding

Contraindicated

JALRA 50MG TABLET is not recommended for use in breastfeeding women or women who plan to breast-feed. Consult your doctor before taking this medicine.

Driving and Using Machines

Use with Caution

Avoid driving or operating machinery if you experience dizziness or other side effects after taking JALRA.

Alcohol

Contraindicated

Avoid consumption of alcohol while taking JALRA 50MG TABLET because it might lead to hypoglycemia (lowering of blood glucose levels).

Kidney

Use with Caution

JALRA 50MG TABLET should be used with caution in patients with moderate or severe kidney disease and in patients who are undergoing dialysis. Consult your doctor before taking this medicine.

Liver

Use with Caution

JALRA 50MG TABLET should be used with caution in patients with liver disease. Regular monitoring of liver enzymes may be needed, and dosage adjustments can be required. Consult your doctor before taking this medicine.

Allergy

Contraindicated

Do not take JALRA if allergic to Vildagliptin or any other components of the tablet.

Heart Disease

Use with Caution

JALRA 50MG TABLET should be used with caution in patients suffering from heart failure. Consult your doctor before taking this medicine.

Use In Pediatrics

Contraindicated

JALRA is not recommended for children and adolescents younger than 18 years due to lack of safety and efficacy data. Consult your paediatrician before giving it. 

Use In Geriatrics

Use with Caution

Elderly patients (65 years and above) should use JALRA cautiously, often with closer monitoring by the doctor. Consult your doctor before taking this medicine. 

Other Warnings for JALRA 50MG TABLET

Before taking JALRA 50mg Tablet, inform your doctor if you:

• Have type 1 diabetes
• Are experiencing diabetic ketoacidosis, a serious diabetes-related condition
• Have intolerance to certain sugars
• Have a history of pancreas disease or current pancreatic problems

Drug - Drug interaction

01) Sulfonylureas (e.g., Glibenclamide, Glimepiride)  

• Interaction: Taking JALRA with sulfonylureas may increase the risk of low blood sugar (hypoglycemia).
• Effects: Higher chance of dizziness, sweating, shaky feeling, or fainting due to low glucose levels.
• Management: Inform your doctor; dose adjustments of either medicine may be needed to avoid hypoglycemia.

02) Metformin 

• Interaction: JALRA can be safely used with metformin without affecting each other's action.
• Effects: Combined use helps better blood sugar control with low risk of increased side effects.
• Management: Always follow prescribed doses; monitor blood sugar regularly for effective management.

03) Insulin 

• Interaction: Using JALRA along with insulin may raise the risk of hypoglycemia.
• Effects: Symptoms like dizziness, sweating, confusion, and weakness might occur more frequently.
• Management: Doctor monitoring is essential; insulin dosage may need adjustment during combined use.

04) Drugs Affecting Blood Sugar (e.g., Corticosteroids, Thyroid Products, Diuretics)

• Interaction: Certain medicines can reduce or enhance the blood sugar-lowering effect of JALRA.
• Effects: This may cause blood sugar to rise or fall unpredictably.
• Management: Inform your healthcare provider about all medicines you take to adjust diabetes therapy correctly.

05) Digoxin

• Interaction: Concomitant use with digoxin requires caution as drug levels in the body might be affected.
• Effects: Changes in digoxin levels can impact heart disease management.
• Management: Close monitoring and dose adjustments may be needed.

06) Warfarin and Other Blood Thinners

• Interaction: Potential for altered effects of blood thinners when taken with JALRA.
• Effects: Increased risk of bleeding or reduced effectiveness of blood thinners.
• Management: Regular blood tests and doctor supervision are important during combined use.

Drug - Food interaction

01) Alcohol

• Interaction: Alcohol can lower blood sugar levels and increase the risk of hypoglycemia when taken with JALRA.
• Effects: Symptoms like dizziness, sweating, shaking, and fainting may occur more frequently.
• Management: Avoid or limit alcohol intake while using JALRA and consult your doctor for advice.

02) High-Sugar or High-Carbohydrate Meals

• Interaction: Consuming large amounts of sugary or carbohydrate-rich foods may reduce the effectiveness of JALRA in maintaining stable blood sugar.
• Effects: This can lead to fluctuations in blood glucose levels that are harder to control.
• Management: Follow a balanced diet with controlled carbohydrate intake as recommended by your healthcare provider.

03) High-Fat Foods

• Interaction: Fatty meals do not directly interact with JALRA but can affect blood sugar control by slowing digestion and glucose absorption.
• Effects: May lead to delayed or unpredictable blood sugar spikes.
• Management: Maintain a healthy and balanced diet, avoiding excessive fried or fatty foods for better diabetes management.

04) ???????Meal Timing

• Interaction: Irregular meal timings or prolonged fasting might affect how JALRA works in controlling blood sugar.
• Effects: Increased risk of low blood sugar or uncontrolled glucose levels.
• Management: Take JALRA consistently and try to maintain regular meal times.

Synopsis

More Information

01. What simple lifestyle changes, like hydration, balanced diet, and exercise, can support diabetes management while using JALRA 50mg Tablet as part of a holistic health approach?

FAQs About JALRA 50MG TABLET

Q: Can JALRA 50MG TABLET be used to manage diabetes mellitus?

A: Yes, JALRA 50MG TABLET lowers blood glucose levels and it is specifically used to manage type II diabetes mellitus which is a medical condition where the body does not make enough insulin or if the produced insulin that the body makes is not optimal leading to increased blood glucose levels in the body. Consult your doctor before taking JALRA 50MG TABLET.

Q: Can I take JALRA 50MG TABLET along with other hypoglycemic drugs like metformin or glimepiride?

A: Using JALRA 50MG TABLET along with other hypoglycemic drugs like metformin, glimepiride may drastically lower your blood glucose levels. So, be cautious and inform your doctor before taking any other anti-diabetic medicines.

Q: Does taking JALRA 50MG TABLET cause weight gain?

A: No, JALRA 50MG TABLET has no effect on weight gain. Moreover, these kinds of medicines delay gastric emptying and make you feel satiety (stomach fullness). These further decreases hunger. So, basically JALRA 50MG TABLET has no effect or it does not influence weight gain.

Q: How does JALRA 50MG TABLET work?

A: JALRA 50MG TABLET controls blood glucose level by acting on the pancreas to produce more insulin and less glucagon which leads to low production of blood sugar levels resulting in controlled blood glucose levels.

Q: Does JALRA 50MG TABLET cause dizziness?

A: Yes, JALRA 50MG TABLET may cause dizziness in some individuals. To manage this effect, lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol and drugs. Consult your doctor if the symptom gets worse.

Q: Can JALRA 50MG TABLET be used in children?

A: JALRA 50MG TABLET is not recommended for use in children and adolescents up to 18 years of age.

Q: What does JALRA 50MG TABLET contain?

A: It contains Vildagliptin which belongs to group of medicines called Oral Anti-diabetics.

References

1. KD. Tripathi. Insulin, Oral Hypoglycaemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page-275.

2. B Ahren, A Schweizer, S Dejager, E B Villhauer, B E Dunning, J E Foley. Mechanisms of action of the dipeptidyl peptidase-4 inhibitor vildagliptin in humans. NIH National Library of Medicine. National Center for Biotechnology Information.PubMed.gov. [Revised in September 2011] [Accessed on 3rd October 2025] 

3. Kalyan Kumar Gangopadhyay and Parminder Singh. Consensus Statement on Dose Modifications of Antidiabetic Agents in Patients with Hepatic Impairment. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in March 2017] [Accessed on 3rd October 2025] 

4. Novartis Europharm Limited. Electronic Medicines Compendium (EMC) [Revised in August 2023] [Accessed on 3rd October 2025] 

5. Novartis Pharma GmbH. European Medicines Agency (EMA). [Revised in July 2012] [Accessed on 3rd October 2025] 

User Feedback

Useful Diagnostic Tests

• HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
• Blood Glucose Fasting (FBS)
• Random Blood Sugar (RBS)
• Post Prandial Blood Sugar (PPBS)
• Routine Diabetes Care
• Diabetes Screening
• Healthians Diabetic Checkup
• Diabetes Care Package

Author Details

Written By Srilekha. R - B.Pharm

Reviewed For Accuracy By Dr. Jaya Prabakaran - MBBS, MD (Diabetology and Family Medicine)

Last updated on 19 Nov 2024 | 04:11 PM(IST)