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Introduction About ITROSTRED OC CREAM
ITROSTRED OC CREAM is a combination of Clobetasol, Itraconazole, Ofloxacin and Ornidazole which belongs to a group of medicines known as Corticosteroids, Antifungals, Antibiotics and Antibacterial. It is used to manage bacterial, fungal infections, skin infections such as dermatitis, inflammatory dermatomes (inflammation of skin region which is related to nerves, and it is characterised by pain, tingling sensation) and lichen planus (irritation and swelling of hair, nails, skin and mucous membranes).
Skin infections caused by bacteria, viruses, fungus, and parasites which is characterised by redness, rashes, itchiness, burning sensation, pain, fever, pus or fluid filled blisters, swelling or inflammation. ITROSTRED OC CREAM should be used with caution in patients having liver and kidney disease. Consult your doctor for advice before using.
If you are a pregnant or breast-feeding woman, ask your doctor for advice before using ITROSTRED OC CREAM. There are limited studies on the use of ITROSTRED OC CREAM in children. Consult with your physician before using. The most common side effects of ITROSTRED OC CREAM are itching, and application site reactions such as burning sensation, redness, or irritation. Consult your doctor if the side effects worsen or persists for a longer duration.
Uses Of ITROSTRED OC CREAM
It is used to manage:
- Dermatitis
- Bacterial infections
- Inflammatory dermatomes
- Fungal infections
- Lichen planus
How ITROSTRED OC CREAM Works
ITROSTRED OC CREAM works effectively against infections where Clobetasol acts by inhibiting the migration of macrophages and leukocytes (white blood cells responsible for causing redness and swelling) into the affected site. Ofloxacin acts against the bacteria. Ornidazole works by inhibiting the protein synthesis necessary for the bacterial growth thereby destroying the bacteria. Itraconazole works by inhibiting the fungal growth by blocking the synthesis of ergosterol, which is necessary for the structure and function of fungal cell membrane.
How to use ITROSTRED OC CREAM
Use ITROSTRED OC CREAM as directed by your physician. It is for external use only. Wash and pat dry the affected area. Apply a thin layer of ITROSTRED OC CREAM to the affected areas and rub it into the skin until it vanishes. Your doctor will decide the right dose depends on your age, body weight and severity of the infection.
Side Effects Of ITROSTRED OC CREAM
Common
- Itching
- Application site reactions such as burning sensation, redness, or irritation
How To Manage Side Effects
Skin rash Or Itching
Avoid taking hot showers as hot water might irritate the skin. Avoid rubbing or scraping at skin rashes. When outdoors, wear protective clothing and apply sunscreen. Regularly moisturize the skin to calm and hydrate the affected area. If the problem gets worse, consult your doctor.
Warning & Precautions
Pregnancy
Consult your doctorIf you are pregnant or you may be pregnant or planning to have a baby, consult your doctor for advice before using ITROSTRED OC CREAM.
Breastfeeding
Consult your doctorIf you are a breastfeeding woman, consult your doctor for advice before using ITROSTRED OC CREAM.
Alcohol
Consult your doctorBefore using ITROSTRED OC CREAM, discuss with your doctor if you have addiction to alcohol.
Kidney
Use with CautionITROSTRED OC CREAM should be used with caution in patients with kidney problems. Consult your doctor before using.
Liver
Use with CautionITROSTRED OC CREAM should be used with caution in patients with liver problems. Consult your doctor before using.
Allergy
ContraindicatedDo not use ITROSTRED OC CREAM if you are allergic to Clobetasol, Itraconazole, Ofloxacin, Ornidazole or any other ingredients of this medicine.
Use In Pediatrics
Consult your doctorThere are limited studies on the use of ITROSTRED OC CREAM in children. Consult with your physician before using.
Use In Geriatrics
Consult your doctorThere is no information available on the use of ITROSTRED OC CREAM in elderly patients. Consult with your physician before using it.
Others
ITROSTRED OC CREAM is not recommended for use if you:
- Have inflammation of hair follicles or acne
- Have rosacea
- Skin itchiness
- Have red rash around the mouth (perioral dermatitis)
- Have extensive plaque psoriasis, excluding single lesions
Before using ITROSTRED OC CREAM inform your doctor if you:
- Have bone pain or worsening of previous bone symptoms
- Have broken or damaged skin or within skin folds
- Have long term leg ulcer
- Have diabetes
- Have chicken pox
Interactions
A. Drug-Drug interactions:
Before using ITROSTRED OC CREAM inform your doctor if you are taking any of the following medicine:
- Ritonavir (medicine used to manage HIV infection)
B. Drug-Food interaction:
Avoid consuming milk and dairy products while using ITROSTRED OC CREAM as it may increase the risk of side effects.
Overdosage:
If you or anyone else accidentally applies too much of ITROSTRED OC CREAM, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Clobetasol, Itraconazole, Ofloxacin, Ornidazole |
| Pharmacological Category | : | Corticosteroids, Antifungals, Antibiotics, Nitroimidazoles |
| Therapeutic Indication | : | Bacterial and Fungal skin infections |
| Dosage Forms | : | Cream, Ointment |
More Information
Storage
- Keep ITROSTRED OC CREAM out of reach of children
- Store at a temperature below 25°C
FAQs About ITROSTRED OC CREAM
Q: What is the use of ITROSTRED OC CREAM?
A: ITROSTRED OC CREAM is used in the management of bacterial and fungal infections, skin infections like dermatitis, inflammatory and lichen planus.
Q: How should ITROSTRED OC CREAM be applied?
A: Always use ITROSTRED OC CREAM as directed by your physician. It is for external use only. Wash as usual and pat dry the affected area. Apply a thin layer of ITROSTRED OC CREAM to the affected areas and carefully rub it into the skin until it vanishes.
Q: Is ITROSTRED OC CREAM safe to use near eyes?
A: No, it not safe to use around the eyes as repeated contact may cause eye problems like cataract and glaucoma. Consult your doctor for advice before using.
Q: Is ITROSTRED OC CREAM safe for use in children?
A: There are limited studies on the use of ITROSTRED OC CREAM in children. Consult with your physician before using.
Q: Does ITROSTRED OC CREAM causes skin rash?
A: Yes, it may cause skin rash in some individuals. Try to avoid hot showers because it may cause skin irritation. Avoid frequent contact and rubbing over the affected area. Use sunscreen and protective clothing when outdoors. If this symptom does not get better, consult your doctor.
References
1. KD Tripathi. Drugs Acting on Skin and Mucous Membranes. Essentials of medical pharmacology. Eighth Edition. 2019. Page- 955.
2. Yehouda Marcus , Noam Tal , Mordechai Ronen , Raanan Carmieli , Michael Gurevitz .The drug ornidazole inhibits photosynthesis in a different mechanism described for protozoa and anaerobic bacteria. National Library of Medicine, National center for biotechnology information. PubMed.gov. September 2019. [Accessed on 2nd February 2023] https://pubmed.ncbi.nlm.nih.gov/27647935/#:~:text=Abstract,of%20toxic%20derivatives%20and%20radicals.
3. Itraconazole. NIH National Library of Medicine, National Centre for biotechnology information. PubChem. February 2023. [Accessed on 2nd February 2023] https://pubchem.ncbi.nlm.nih.gov/compound/Itraconazole
4. Ofloxacin. NIH National Library of Medicine, National Centre for biotechnology information. PubChem. August 2022. [Accessed on 2nd February 2023] https://pubchem.ncbi.nlm.nih.gov/compound/Ofloxacin
5. Glaxo Operations UK Ltd. Electronic Medicines Compendium (EMC). [Revised in May 2022] [Accessed on 2nd February 2023] https://www.medicines.org.uk/emc/files/pil.939.pdf
6. Ikon Remedies Pvt Ltd. OFLOWIN PLUS Cream 15gm. [Accessed on 2nd February 2023] https://www.ikonremedies.com/product/oflowin-plus-cream/
7. Soignerpharma. ITCHWAR CREAM. [Accessed on 2nd February 2023] https://www.soignerpharma.com/product/ofloxacin-ornidazole-itraconazole-clobetasol-propionate-cream/
8. Integrated laboratories. Ofcin-CT. [Accessed on 2nd February 2023] https://integratedlaboratories.in/ofloxacin-ornidazole-itraconazole-clobetasol-ofcin-ct/
Useful Diagnostic Tests
- Complete blood count
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