Intas Pharmaceuticals Ltd

INTAGESIC Gel 10gm

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Introduction About INTAGESIC GEL

INTAGESIC GEL is a combination of Diclofenac, Menthol, Methyl Salicylate, and Oleum Lini which belongs to the group of medicines called Non-steroidal Anti-inflammatory Drug (NSAID), Cooling agents, Analgesics and Emollient respectively. It is used to relieve pain, swelling and inflammation due to musculoskeletal disorders such as sprains, strains, tendonitis, bursitis, hand, neck and shoulder pain, sciatica, muscle stiffness, joint pain, back ache and lumbago.

Avoid exposure to sunlight after applying INTAGESIC GEL. It is not recommended for use in patients who have gastrointestinal bleeding, hepatic porphyria, fluid retention, heart failure, and hypertension. Before using INTAGESIC GEL inform your doctor if you have anemia and asthma. INTAGESIC GEL is not recommended for use in women who are pregnant, especially in the third trimester of pregnancy and it should be used with caution in breastfeeding women.

Caution must be exercised while using INTAGESIC GEL in elderly patients. The most common side effects of using INTAGESIC GEL are skin irritation, redness of the skin, rashes, dermatitis, burning or stinging sensation at the site of application. Consult your doctor’s advice if any of these above side effects worsen or persists for a longer duration.

Uses Of INTAGESIC GEL

It is used to relieve pain, swelling and inflammation due to:

  • sprains
  • strains
  • tendonitis
  • bursitis
  • hand, neck and shoulder pain
  • sciatica
  • muscle stiffness
  • joint pain
  • back ache
  • lumbago

How INTAGESIC GEL Works

INTAGESIC GEL helps in relieving pain and swelling whereas Diclofenac belongs to NSAID that causes relief in pain and inflammation by inhibiting the factors that cause inflammation and pain called prostaglandins. Methyl salicylate acts by dilating the blood vessels and increasing blood flow. It causes irritation of the skin and because of counter-irritation, there is a sensation of warmth and relief in musculoskeletal pain. Menthol acts by acting as an irritant and imparts coolness to the skin and then warmth. Oleum lini is a plant-based oil that reduces swelling and improves blood circulation.  

How to use INTAGESIC GEL

Apply INTAGESIC GEL as advised by your physician. It is for external use only. Gently apply INTAGESIC GEL on the affected area. Your doctor will prescribe the right dose depends on your age, body weight and disease condition.

Side Effects Of INTAGESIC GEL

Common

  • skin irritation
  • redness of the skin
  • rashes, dermatitis, burning or stinging sensation at the site of application

Warning & Precautions

Pregnancy

Monitoring required

INTAGESIC GEL is not recommended to use in pregnant women especially in the third trimester of pregnancy unless considered clearly necessary. Consult your doctor before using it.

Breastfeeding

Contraindicated

INTAGESIC GEL is not recommended to use in breastfeeding women as it may excrete in breast milk. Consult your doctor before using it.

Liver

Contraindicated

INTAGESIC GEL is not recommended for use in patients with hepatic porphyria. Consult your doctor before using.

Allergy

Contraindicated

Do not use INTAGESIC GEL if you are allergic to Diclofenac, Menthol, Methyl Salicylate, Oleum Lini, or any other ingredients of this medicine.

Lungs

Contraindicated

INTAGESIC GEL is not recommended for use in patients with asthma. Consult your doctor before using.

Heart Disease

Contraindicated

INTAGESIC GEL is not recommended for use in patients having heart diseases such as heart failure or hypertension. Consult your doctor before using.

Use In Pediatrics

Consult your doctor

Your doctor will decide the correct dose and duration of the management depending on your child’s age, disease condition, and body weight. Consult your doctor before using INTAGESIC GEL.

Use In Geriatrics

Use with Caution

In elderly patients, INTAGESIC GEL should be used with caution. Your doctor will decide the correct dose and duration of the management depending on your age, disease condition, and body weight. Consult your doctor before using.

Others

INTAGESIC GEL is not recommended for use if you have:

  • gastro intestinal bleeding

Before using INTAGESIC GEL, inform your doctor if you have:

  • anemia

Interactions

A. Drug-Drug Interactions:

Before using INTAGESIC GEL inform your doctor if you are taking or using any medicines, including medicines obtained with prescription, non-prescription and herbal preparations.

Overdosage:

In case of accidental ingestion or too much application of INTAGESIC GEL, consult your doctor immediately or visit the nearby hospital.

Synopsis

Drug :   Diclofenac, Menthol, Methyl Salicylate, Oleum lini
Pharmacological Category :   Non-steroidal Anti-inflammatory Drug (NSAID) Cooling agents, Analgesics, Emollient
Therapeutic Indication :   Pain relief
Dosage Forms :   Gel, Cream, Nanogel

More Information

  • Keep INTAGESIC GEL out of reach of children
  • Store below 30°C

FAQs About INTAGESIC GEL

Q: Can INTAGESIC GEL be used in pregnant and breastfeeding women?

A: No. INTAGESIC GEL is not recommended to use among women who are pregnant (third trimester of pregnancy) and breastfeeding unless considered clearly necessary. Consult your doctor before using it.

Q: Does INTAGESIC GEL cause skin irritation?

A: Yes, INTAGESIC GEL may cause skin irritation. INTAGESIC GEL contains Methyl Salicylate which acts by dilating the blood vessels and increasing blood flow. It causes irritation of the skin and because of counter-irritation, there is a sensation of warmth and relief in musculoskeletal pain.

Q: Is INTAGESIC GEL safe for use in children?

A: Your doctor will decide the correct dose and duration of the management depending on your age, disease condition, and body weight. Consult your doctor before using INTAGESIC GEL.

Q: In which condition INTAGESIC GEL should not be used?

A: INTAGESIC GEL is not recommended for use in patients who have GI bleeding, hepatic porphyria, heart failure and hypertension. Consult your doctor before using.

References

1. K.D. Tripathi. NSAIDs and Antipyretic Analgesics, Drugs Acting on Skin and Mucous Membranes. Essentials of medical pharmacology. Seventh edition. 2013. Page – 204, 888 & 889.

2. NIH National Library of Medicine, National center for biotechnology information. Pubchem. Diclofenac Sodium. [Accessed on 16th August 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Diclofenac

3. NIH National Library of Medicine, National center for biotechnology information. Pubchem. Methyl Salicylate. [Accessed on 16th August 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Methyl-salicylate

4. J V Pergolizzi Jr, R Taylor Jr, J-A LeQuang, R B Raffa, NEMA Research Group. The role and mechanism of action of menthol in topical analgesic products. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. June 2018. [Accessed on 16th August 2022] https://pubmed.ncbi.nlm.nih.gov/29524352/#:~:text=Results%3A%20Menthol%20is%20a%20selective,nociceptors%20and%20then%20desensitizing%20them.

5. Astraea Life Sciences. Hivolt 4X Nano Gel. [Accessed on 17th August 2022] https://astraeaglobal.com/hivolt-4x-nano-gel/

6. Solace Biotech Limited. Movogesic gel. [Accessed on 17th August 2022] http://solaceworld.org/movogesic-gel-30gm/

7. Karnataka Antibiotics and Pharmaceutical Limited. Oligel [Accessed on 17th August 2022] https://www.kaplindia.com/oligel/

Author Details

Written By Dr. Janet.C - Pharm.D
Reviewed For Accuracy By Dr. Sankara Babu Gorle - MBBS, MD (Pharmacology)
Last updated on 24 Feb 2023 | 11:18 PM(IST)
Lab updated