Indocap SR 75mg Capsule 10'S

Introduction About INDOCAP SR 75MG CAPSULE

Indocap SR 75mg Capsule 10'S is an oral sustained-release formulation containing indomethacin, a non-steroidal anti-inflammatory medicine commonly used as part of medical care plans for pain, swelling, and inflammation. It may be considered for conditions such as arthritis, musculoskeletal pain, and other inflammatory conditions where reducing discomfort and inflammation is required. The medicine works by reducing the production of prostaglandins, substances involved in pain and inflammation, thereby helping improve mobility and day-to-day comfort.  

This capsule is generally prescribed for adults who require longer-lasting symptom control under medical supervision. Indocap SR 75mg Capsule is intended for oral use only and is usually taken once daily or as directed by a healthcare professional. It should be swallowed whole with water and should not be crushed, chewed, or opened, as it is a sustained-release formulation. Taking it with or after food may help reduce stomach discomfort. The dose and duration should be followed exactly as prescribed.

While using Indocap SR 75mg Capsule, certain precautions should be followed. Avoid taking it along with other NSAIDs, such as ibuprofen, diclofenac, or naproxen, unless specifically advised by your doctor, as this may increase the risk of side effects. Inform your doctor about all medicines and supplements you are taking, particularly blood thinners, corticosteroids, medicines for blood pressure, or other pain-relieving medicines. Avoid excessive alcohol consumption, as it may increase the risk of stomach-related side effects.

Indocap SR 75mg Capsule should be used cautiously in individuals with a history of stomach ulcers or gastrointestinal bleeding, kidney or liver problems, heart disease, high blood pressure, or asthma triggered by NSAIDs. It may not be suitable during certain stages of pregnancy, particularly in the later months, and should be used during pregnancy or breastfeeding only after medical consultation. Common side effects may include indigestion, nausea, stomach discomfort, headache, dizziness, or diarrhoea. If severe stomach pain, black stools, vomiting blood, breathing difficulty, swelling, or other unusual reactions occur, seek medical attention promptly.

Uses Of INDOCAP SR 75MG CAPSULE

• Helps relieve pain and inflammation associated with arthritis and other musculoskeletal conditions.  
• Supports the management of joint pain, stiffness, and swelling associated with inflammatory conditions.
• Provides relief from acute pain and inflammation caused by conditions such as gout, bursitis, or tendinitis.
• May help reduce pain and inflammation following certain injuries or procedures, as advised by a healthcare professional.

Benefits of INDOCAP SR 75MG CAPSULE

Indocap SR 75mg Capsule for Pain and Inflammation Management

Indocap SR 75mg Capsule is used to help manage pain, swelling, and inflammation associated with conditions such as arthritis and other musculoskeletal disorders. It works by reducing substances in the body that contribute to pain and inflammation.

Indocap SR 75mg Capsule for Joint Pain and Stiffness

Indocap SR 75mg Capsule is used to help manage joint pain, tenderness, and stiffness associated with inflammatory joint conditions. It may help reduce these symptoms and improve day-to-day comfort when taken as prescribed.

Indocap SR 75mg Capsule for Acute Pain and Inflammatory Conditions

Indocap SR 75mg Capsule is used to help manage acute pain and inflammation associated with conditions such as gout, bursitis, or tendinitis. It should be used according to the dose and duration recommended by a healthcare professional.

How INDOCAP SR 75MG CAPSULE Works

How Indocap SR 75mg Capsule Works in the Body

Indocap SR 75mg Capsule contains Indomethacin, a non-steroidal anti-inflammatory medicine (NSAID). It works by reducing the production of prostaglandins, substances in the body that play a role in causing pain, swelling, and inflammation.

How Indomethacin Affects Prostaglandins

Indomethacin inhibits cyclooxygenase (COX) enzymes, which are involved in the production of prostaglandins. This action reduces the levels of these substances and helps control the inflammatory response.

How Indocap SR 75mg Capsule Helps Control Symptoms

By reducing prostaglandin production, Indocap SR 75mg Capsule may help relieve symptoms such as pain, stiffness, and swelling. This can help improve comfort and mobility when the medicine is used as directed by a healthcare professional.

How to use INDOCAP SR 75MG CAPSULE

How to take Indocap SR 75mg Capsule

• Take Indocap SR 75mg Capsule exactly as prescribed by your doctor.
• Swallow the capsule whole with a glass of water.
• Do not crush, chew, or open the capsule, as it is a sustained-release formulation.
• It may be taken with or after food to reduce the chance of stomach discomfort.
• Try to take it at the same time each day if it has been prescribed for regular use.
• Do not take more than the recommended dose or use it for longer than advised.
• Avoid taking other NSAID painkillers along with Indocap SR unless your doctor recommends them.
• If you miss a dose, take it when you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed one.

What if I forgot to take INDOCAP SR 75MG CAPSULE

• Take the missed dose as soon as you remember.
• If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
• Do not take two doses at the same time to make up for the missed dose.
• Try to take the capsule at the same time each day to help avoid missed doses.
• If you frequently forget your doses, speak with your healthcare professional for advice on maintaining a regular schedule.

Overdose

If more than the prescribed amount of Indocap SR 75mg Capsule is taken, seek immediate medical attention. Overdosage may increase the risk of side effects such as nausea, vomiting, stomach pain, dizziness, headache, drowsiness, or gastrointestinal bleeding. Do not take an additional dose to compensate for a missed dose or without medical advice.

Side Effects Of INDOCAP SR 75MG CAPSULE

Common side effects of Indocap SR 75mg Capsule 10'S

• Nausea or vomiting
• Indigestion or heartburn
• Stomach pain or discomfort
• Diarrhoea or constipation
• Headache
• Dizziness or drowsiness
• Loss of appetite

When to Seek Medical Attention?

Stop using Indocap SR 75mg Capsule 10'S and contact your doctor immediately if you experience

• Severe or persistent stomach pain, indigestion, or heartburn
• Vomiting blood or material that looks like coffee grounds
• Black, tarry, or bloody stools
• Severe skin rash, blistering, or peeling
• Swelling of the face, lips, tongue, or throat
• Difficulty breathing, wheezing, or severe allergic reactions
• Sudden chest pain, weakness, or difficulty speaking
• Unusual or significantly reduced urine output
• Yellowing of the skin or eyes, which may indicate liver problems
• Any other severe, unusual, or worsening symptoms after taking the medicine.

How To Manage Side Effects

Headache

• Drink enough water: Dehydration can contribute to headaches, so sip water regularly.
• Rest in a quiet, dark room: Reduce bright lights and loud sounds, especially if they make the headache worse.
• Apply a cold or warm compress: A cold pack on the forehead may help some headaches, while a warm compress around the neck or shoulders may help if muscle tension is involved.
• Have a light meal: Skipping meals can sometimes trigger headaches. Choose a simple, balanced meal if you have not eaten for several hours.
• Try gentle neck and shoulder stretches: This may help when the headache is associated with muscle tension.
• Limit screen time: Take regular breaks from phones, computers, and other screens.
• Get adequate sleep: Maintain a regular sleep schedule and avoid excessive sleep deprivation.
• Reduce caffeine gradually: If you regularly consume a lot of caffeine, sudden withdrawal can contribute to headaches.

Loss Of Appetite

• Eat small, frequent meals: Try 5–6 smaller meals instead of 2–3 large meals.
• Choose nutrient-rich foods: Include eggs, curd, dal, fruits, vegetables, nuts, and whole grains according to your preference.
• Stay hydrated: Drink water regularly but avoid consuming large amounts immediately before meals.
• Try ginger or lemon: Ginger tea or a little lemon added to water may help make meals more appealing for some people.
• Include favourite foods: Choosing foods you enjoy may make eating easier when your appetite is low.
• Avoid excessive tea, coffee, or alcohol: These may affect appetite or make it harder to maintain regular meals.
• Stay physically active: A gentle walk may help stimulate appetite and support digestion.
• Maintain regular mealtimes: Eating at consistent times can help establish a routine even when you do not feel very hungry.

Warning & Precautions

Pregnancy

Consult your doctor

Indocap SR 75mg Capsule should be avoided during pregnancy unless specifically prescribed by a healthcare professional. Indomethacin, particularly during the later stages of pregnancy, may cause risks to the developing baby and pregnancy.

Breastfeeding

Consult your doctor

Indomethacin can pass into breast milk in small amounts. Consult a healthcare professional before using Indocap SR 75mg Capsule while breastfeeding.

Driving and Using Machines

Use with Caution

Indocap SR 75mg Capsule may cause dizziness, drowsiness, or headache in some individuals. Avoid driving or operating machinery if you experience these effects.

Alcohol

Contraindicated

Avoid drinking alcohol while taking Indocap SR 75mg Capsule, as combining alcohol with this medicine may increase the risk of stomach irritation, dizziness, or other side effects.

Kidney

Use with Caution

Patients with kidney problems should use Indocap SR 75mg Capsule cautiously and only under medical supervision, as NSAIDs may affect kidney function.

Liver

Consult your doctor

Individuals with liver problems should inform their doctor before using Indocap SR 75mg Capsule. Medical monitoring may be recommended during prolonged use.

Allergy

Contraindicated

Do not use Indocap SR 75mg Capsule if you are allergic to indomethacin, other NSAIDs, or any component of the medicine. Inform your doctor about any previous allergic reactions to painkillers.

Lungs

Use with Caution

Use Indocap SR 75mg Capsule cautiously if you have asthma, particularly if previous use of aspirin or other NSAIDs has caused breathing difficulties or allergic reactions.

Heart Disease

Consult your doctor

Patients with heart disease, high blood pressure, or a history of stroke should use Indocap SR 75mg Capsule only after medical advice, as NSAIDs may increase cardiovascular risks, particularly with prolonged use.

Use In Pediatrics

Contraindicated

Indocap SR 75mg Capsule is generally not recommended for children unless specifically prescribed by a healthcare professional, with dosing determined according to the child's condition and requirements.

Use In Geriatrics

Consult your doctor

Older adults may be more susceptible to stomach, kidney, heart, and other NSAID-related side effects. Indocap SR 75mg Capsule should therefore be used at the lowest effective dose for the shortest appropriate duration under medical supervision.

Other Warnings for INDOCAP SR 75MG CAPSULE

Before using Indocap SR 75mg Capsule 10'S inform your doctor if you

• Have a history of stomach ulcers, gastritis, or gastrointestinal bleeding.
• Have heart disease, high blood pressure, or a history of stroke.
• Are scheduled for surgery, particularly if it involves the heart or if you have a procedure where bleeding risk is important.

Safety Advice

• Take Indocap SR 75mg Capsule only as prescribed and use the lowest effective dose for the shortest appropriate duration.
• Swallow the sustained-release capsule whole with water; do not crush or chew it.
• Avoid taking other NSAID painkillers such as ibuprofen, naproxen, or diclofenac unless specifically advised by your doctor.
• Inform your doctor if you have a history of stomach ulcers, gastrointestinal bleeding, kidney disease, liver problems, heart disease, high blood pressure, or asthma related to aspirin/NSAIDs.
• NSAIDs such as indomethacin can increase the risk of stomach bleeding, ulcers, and cardiovascular events; seek medical attention for severe stomach pain, black stools, vomiting blood, chest pain, or sudden weakness.
• Stay adequately hydrated, particularly if you have conditions that may affect kidney function. Kidney function may require monitoring in people with kidney or liver impairment, heart failure, dehydration, or low blood volume.
• Tell your doctor about all medicines you take, especially blood thinners, diuretics, blood-pressure medicines, corticosteroids, and other NSAIDs, because interactions may occur.
• Avoid or limit alcohol, as it may increase the risk of gastrointestinal irritation or bleeding.
• If you develop a skin rash, facial swelling, breathing difficulty, or other signs of a serious allergic reaction, stop using the medicine and seek urgent medical attention.
• Do not use Indocap SR around coronary artery bypass graft (CABG) surgery unless specifically directed by the treating medical team.

Diet and Lifestyle Advice

• Take the capsule with food or immediately after a meal to help reduce stomach discomfort. Swallow the sustained-release capsule whole with water. Maintain a balanced diet with adequate vegetables, fruits, whole grains, and protein sources unless your doctor has advised a specific diet.
• Stay adequately hydrated by drinking sufficient water throughout the day, unless you have been advised to restrict fluids.
• Limit or avoid alcohol, as alcohol can increase the risk of stomach irritation and bleeding associated with indomethacin.
• Avoid taking additional NSAID painkillers such as ibuprofen, naproxen, or diclofenac unless your doctor specifically recommends them.
• Maintain a healthy body weight and follow gentle, regular physical activity as appropriate for your underlying condition.
• Avoid smoking, as smoking can increase gastrointestinal risks associated with NSAID use.
• Follow your prescribed dose and duration rather than increasing the dose when pain becomes worse. Using the lowest effective dose for the shortest appropriate duration can reduce risks.
• If you develop severe stomach pain, black stools, vomiting blood, swelling, reduced urine output, or breathing difficulty, seek medical attention promptly.

1.Indocap SR 75mg Capsule and Diclofenac – Pain and Inflammation Management

Drug - Drug interaction

1. Other NSAIDs (e.g., ibuprofen, diclofenac, naproxen)

• Interaction: Taking Indocap SR with other NSAIDs may increase the risk of stomach ulcers, gastrointestinal bleeding, and kidney-related side effects.
• Management: Avoid combining these medicines unless specifically advised by your doctor.

2. Blood Thinners (e.g., warfarin, apixaban, aspirin)

• Interaction: Indomethacin may increase the risk of bleeding when used with anticoagulants or antiplatelet medicines.
• Management: Inform your doctor if you take blood-thinning medicines. Medical monitoring may be required.

3. Corticosteroids (e.g., prednisolone, dexamethasone)

• Interaction: Combining corticosteroids with indomethacin may increase the risk of stomach ulcers and gastrointestinal bleeding.
• Management: Use together only under medical supervision and report unusual stomach pain or bleeding.

4. Blood Pressure Medicines (e.g., enalapril, losartan, amlodipine)

• Interaction: Indomethacin may reduce the blood-pressure-lowering effect of some antihypertensive medicines and may affect kidney function.
• Management: Inform your doctor if you are taking medicines for high blood pressure. Blood pressure and kidney function may need monitoring.

5. Diuretics or Water Tablets (e.g., furosemide, hydrochlorothiazide)

• Interaction: Indomethacin may reduce the effectiveness of diuretics and increase the risk of kidney problems in susceptible individuals.
• Management: Use under medical supervision, particularly if you have kidney or heart problems.

6. Lithium

• Interaction: Indomethacin may increase lithium levels in the blood, potentially increasing the risk of lithium-related side effects.
• Management: If both medicines are prescribed, your doctor may monitor lithium levels and adjust the dose when necessary.

7. Methotrexate

• Interaction: Indomethacin may increase methotrexate exposure and potentially increase the risk of toxicity.
• Management: Inform your doctor if you are taking methotrexate so that appropriate monitoring can be arranged.

8. Cyclosporine or Tacrolimus

• Interaction: Combining these medicines with indomethacin may increase the risk of kidney-related side effects.
• Management: Use only under medical supervision, with kidney function monitored when appropriate.

9. Herbal Supplements and Other Medicines

• Interaction: Some herbal products and over-the-counter medicines may interact with indomethacin or increase the risk of side effects.
• Management: Inform your doctor or pharmacist about all prescription medicines, OTC products, vitamins, and herbal supplements you use before starting Indocap SR.

Drug - Food interaction

1. Alcoholic Beverages

• Interaction: Alcohol may increase stomach irritation and can raise the risk of gastrointestinal ulcers or bleeding when taken with indomethacin.
• Management: Avoid or limit alcohol while using Indocap SR 75mg Capsule.

2. Caffeine-Containing Beverages (e.g., coffee, tea, energy drinks)

• Interaction: There is no well-established major direct interaction between caffeine and indomethacin. However, excessive caffeine may contribute to stomach discomfort in some individuals.
• Management: Consume caffeinated beverages in moderation and monitor how your body responds.

3 Salty Foods

• Interaction: High sodium intake may contribute to fluid retention and increased blood pressure, which can be a concern with NSAID medicines such as indomethacin.
• Management: Limit excessive salt intake, particularly if you have high blood pressure, heart problems, or swelling.

Synopsis

More Information

FAQs About INDOCAP SR 75MG CAPSULE

Q: What is Indocap SR 75mg Capsule used for?

A: Indocap SR 75mg Capsule contains Indomethacin, a non-steroidal anti-inflammatory medicine (NSAID) used under medical guidance to help manage pain, swelling, and inflammation associated with conditions such as arthritis and other musculoskeletal disorders.

Q: How does Indocap SR 75mg Capsule work?

A: It works by reducing the production of prostaglandins, substances involved in pain and inflammation. This helps reduce pain, swelling, and stiffness.

Q: Can I take Indocap SR 75mg Capsule daily?

A: It may be prescribed for daily use depending on your condition. Take it only at the dose and duration recommended by your doctor, as prolonged NSAID use can increase the risk of certain side effects.

Q: Do I need any tests while taking Indocap SR 75mg Capsule?

A: Routine testing may not be necessary for everyone. However, your doctor may recommend monitoring kidney function, liver function, blood pressure, or blood counts during prolonged use or if you have certain underlying health conditions.

Q: Can diet affect Indocap SR 75mg Capsule?

A: Taking the capsule with or after food may help reduce stomach discomfort. Avoid excessive alcohol consumption, as it may increase the risk of stomach irritation and gastrointestinal bleeding.

Q: What should I avoid while taking Indocap SR 75mg Capsule?

A: Avoid taking other NSAID painkillers, such as ibuprofen, naproxen, or diclofenac, unless specifically advised by your doctor. Also avoid unnecessary medicines or supplements without medical advice.

Q: Can Indocap SR 75mg Capsule cause side effects?

A: Yes. Common side effects may include indigestion, nausea, stomach discomfort, headache, dizziness, diarrhoea, or constipation. Contact your doctor if symptoms are severe or persistent.

Q: Is Indocap SR 75mg Capsule safe for long-term use?

A: Long-term use should be undertaken only under medical supervision. Extended NSAID use may increase the risk of gastrointestinal, kidney, liver, and cardiovascular complications, particularly in people with existing health conditions.

Q: Can I stop taking Indocap SR 75mg Capsule suddenly?

A: If it has been prescribed for regular or prolonged use, consult your doctor before stopping it. Your doctor can advise whether it should be discontinued based on your condition and duration of use.

Q: Can Indocap SR 75mg Capsule be taken with other medicines?

A: Some medicines may interact with indomethacin, including blood thinners, corticosteroids, other NSAIDs, diuretics, blood-pressure medicines, lithium, and methotrexate. Inform your doctor about all prescription medicines, OTC medicines, vitamins, and supplements you use.

References

1. KD. Tripathi. Nonsteroidal Anti-inflammatory Drugs and Antipyretic-Analgesics. Essentials of medical pharmacology. 8th edition. 2013. Page – 202.

2. Supakanya Wongrakpanich, Amaraporn Wongrakpanich, Katie Melhado, and Janani Rangaswami. A Comprehensive Review of Non-Steroidal Anti-Inflammatory Drug Use in The Elderly. NIH National Library of Medicine. National centre for biotechnology information. PMC PubMed Central. [Revised in February 2018]. [Accessed on 1st September 2026]

3. Sylvia Lucas. The Pharmacology of Indomethacin. NIH National Library of Medicine. National centre for biotechnology information. PubMed.gov. [Revised in February 2016]. [Accessed on 1st September 2026]

4. Iroko Pharmaceuticals, LLC. Food & Drug Administration (FDA). [Revised in May 2016] [Accessed on 1st September 2026]

5. Indomethacin. Mayoclinic. [Revised in 1st July 2026] [Accessed on 1st September 2026] 

Useful Diagnostic Tests

• Kidney Function Test (KFT) 
• Liver Function Test (LFT)

Author Details

Written By Dr. R. Dinesh John Rajkumar - Pharm.D

Reviewed For Accuracy By Dr. Sankara Babu Gorle - MBBS, MD (Pharmacology)

Last updated on 03 Sep 2026 | 03:05 PM(IST)