INDIPIL AM 10 Tablet 10's

Introduction About INDIPIL AM 10 TABLET

INDIPIL AM 10 TABLET is a combination of Amlodipine and Indapamide, which belong to the group of medicines called Calcium-channel blockers and Thiazide diuretics. It is used in the management of high blood pressure (hypertension), which is a condition in which the force of the blood is consistently high against the walls of the arteries, which can increase the risk of heart disease, kidney disease and stroke.

Inform your doctor if you are pregnant or breastfeeding before taking this medicine. Inform your doctor if you have any problems related to the kidney, liver or heart. If you are elderly and younger than 18 years old, you should consult with a doctor before taking the medicine.

Before taking INDIPIL AM 10 TABLET, inform your doctor if you have any conditions such as diabetes, low blood pressure, gout, low levels of potassium in the blood (hypokalaemia) and symptoms of fluid accumulation around the eye that present with visual disturbances or eye pain. The most common side effects of taking INDIPIL AM 10 TABLET are headache, nausea, dizziness and tiredness.

Uses Of INDIPIL AM 10 TABLET

• Manage hypertension (high blood pressure)

How INDIPIL AM 10 TABLET Works

INDIPIL AM 10 TABLET helps to reduce high blood pressure, where amlodipine works by inhibiting the movement of calcium ions into both vascular smooth muscle and cardiac muscle, resulting in lower blood pressure by relaxing the blood vessels and improving the flow of blood to the heart muscles. Indapamide reduces blood pressure by promoting the excretion of extra fluid and certain salts (sodium) from the body by increasing the amount of urine produced by the kidneys.

How to use INDIPIL AM 10 TABLET

Always take INDIPIL AM 10 TABLET as instructed by your doctor. Take INDIPIL AM 10 TABLET with or without food, swallow the medicine as a whole and do not crush or chew the medicine. Do not stop taking the medicine without informing your doctor.

Overdose

If you or anyone else accidentally takes too much of INDIPIL AM 10 TABLET, consult your doctor immediately. Overdosage may cause side effects such as dizziness, light-headedness, nausea, cramps, flushing (redness of the skin), fainting, low blood pressure, urinary problems, drowsiness and confusion.

Side Effects Of INDIPIL AM 10 TABLET

Common side effects of INDIPIL AM 10 TABLET:

• headache
• dizziness
• nausea
• stomach pain
• visual disturbances
• muscle cramps
• diarrhea
• constipation
• indigestion
• increased heart rate
• flushing (skin redness)
• weakness, tiredness
• oedema (fluid retention)
• reduced levels of potassium in the blood
• red raised rashes on the skin

Stop taking this medicine and contact your doctor immediately if you experience any of the following side effects:

• severe skin reactions such as stevens-johnson syndrome, toxic epidermal necrolysis (skin rash, itching, blistering reddening of skin all over the body, peeling and swelling of the skin, swelling of the mucous membrane)
• heart attack or irregular heartbeat
• signs of an inflamed pancreas (severe stomach and back pain, usually feeling unwell)
• sudden chest pain, wheezing and trouble breathing
• angioedema or urticaria (such as rash, swelling of the face, lips, mouth, throat or airways which can lead to difficulty in breathing or swallowing)

How To Manage Side Effects

Diarrhea

Drink plenty of fluids, such as water, fruit juices or electrolytes (ORS), to avoid dehydration in your body. Consult your doctor if the symptoms do not improve.

Dizziness Or Drowsiness

Lie down until the dizziness passes away and then move slowly and carefully. Take plenty of rest and drink plenty of fluids. Consult your doctor if the symptoms do not improve.

Headache

Apply a hot or cold-water bag to your head. Try taking a rest in a quiet and dark room. Drink tea or coffee. Consult your doctor if the symptoms do not improve.

Nausea And Vomiting

Try to take INDIPIL AM 10 TABLET with or just after, a meal or snack, stick to simple meals and do not eat oil-rich or spicy food. Consult your doctor if the symptoms do not improve.

Stomach Pain

Take some time to rest and relax. Eat and drink slowly or try to have smaller, more frequent meals. Keep a heating pad on your stomach. If the symptom does not improve, contact your doctor.

Warning & Precautions

Pregnancy

Contraindicated

INDIPIL AM 10 TABLET should not be used by pregnant women. Consult with your doctor for advice before taking the medicine.

Breastfeeding

Contraindicated

INDIPIL AM 10 TABLET is not recommended for use by breastfeeding women. Consult with your doctor for advice before taking the medicine.

Driving and Using Machines

Use with Caution

INDIPIL AM 10 TABLET may cause side effects such as dizziness or tiredness due to low blood pressure, so use caution while driving or operating heavy machinery.

Alcohol

Contraindicated

Consumption of alcohol is not recommended during management with INDIPIL AM 10 TABLET.

Kidney

Consult your doctor

INDIPIL AM 10 TABLET should be used with caution in patients with kidney disease undergoing dialysis and it is not recommended for use in patients with severe kidney disease. Consult with your doctor for advice before taking INDIPIL AM 10 TABLET.

Liver

Consult your doctor

INDIPIL AM 10 TABLET should be used with caution in liver disease patients and it is not recommended for use in patients with severe liver disease. Consult with your doctor for advice before taking INDIPIL AM 10 TABLET.

Allergy

Contraindicated

Do not take this medicine if you are allergic to Amlodipine and Perindopril or other inactive preparations of this medicine.

Heart Disease

Contraindicated

INDIPIL AM 10 TABLET should not be used in patients with heart problems such as heart failure, recent heart attack, narrowing of the aortic heart valve (aortic stenosis) or cardiogenic shock (where the heart is unable to pump a sufficient amount of blood to the body).

Use In Pediatrics

Contraindicated

INDIPIL AM 10 TABLET is not recommended for use in children under 18 years of age. Consult your doctor for advice.

Use In Geriatrics

Use with Caution

INDIPIL AM 10 TABLET should be used with caution in elderly patients and the dose may be adjusted according to age and weight. The management should be initiated based on kidney, liver or heart function.

Other Warnings for INDIPIL AM 10 TABLET

Before taking INDIPIL AM 10 TABLET, inform your doctor if you have:

• severe increase in blood pressure
• diabetes
• gout (joint pain and swelling)
• allergic problems with natural sunlight or UV rays (photosensitivity reactions)
• symptoms of fluid accumulation in the vascular layer of the eye (choroidal effusion) or increase in eye pressure such as eye pain or low eye vision

Who should not take INDIPIL AM 10 TABLET

Do not take INDIPIL AM 10 TABLET, if you have:

• hepatic encephalopathy
• severe low blood pressure

Drug - Drug interaction

Inform your doctor, if you are taking any of the following medicines

• ketoconazole, itraconazole, amphotericin B (used to manage fungal infections)
• verapamil, diltiazem (used to manage low blood pressure)
• phenobarbital, phenytoin, carbamazepine (used to manage seizures)
• erythromycin, clarithromycin, rifampicin (used to manage bacterial infections)
• nefazodone (used to manage depression)
• dantrolene infusion (used to manage body temperature abnormalities)
• tacrolimus (used to alter the immune system response)
• simvastatin (used to manage high cholesterol)
• St. john’s wort (herbal preparation used to manage depression)
• ritonavir, nelfinavir, indinavir (used to manage HIV)
• sildenafil (used to manage impotence)
• metformin (used to manage diabetes)
• allopurinol (used to manage gout)
• quinidine, amiodarone, hydroquinidine (used to manage heart rhythm disorder)
• bepridil (used to manage chest pain)
• diphemanil, cisapride (used to manage stomach ulcers)
• pentamidine (used to manage malaria)
• halofantrine (manages certain types of malaria)
• ibuprofen (used to manage swelling and pain)
• calcium supplements
• potassium-sparing diuretics such as spironolactone and amiloride (used to manage high blood pressure or heart failure)

Drug - Food interaction

Do not eat grapefruit or drink grapefruit juice while taking this medicine as it increases the level of this medicine in the blood, resulting in blood pressure-lowering effects. Consult your doctor before taking INDIPIL AM 10 TABLET.

Synopsis

More Information

• Keep INDIPIL AM 10 TABLET medicine out of reach from children
• Store at normal room temperature below 25°CfF

FAQs About INDIPIL AM 10 TABLET

References

1. KD Tripathi. Antihypertensive Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 558 & 561.

2. Uday Jadhav, Jagdish Hiremath, Deepak J Namjoshi, Vinod K Gujral, Kamlakar K Tripathi, Mohammad Siraj, Paramesh Shamanna, Michel Safar. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. April 2014. [Accessed on 27th June 2026]

3. Zh. D. Kobalava, Eteri L. Kolesnik, E. K. Shavarova, L. A. Goreva & L. V. Karapetyan. Effectiveness of indapamide/amlodipine single-pill combination in patients with isolated systolic hypertension: a posthoc analysis of the ARBALET study. BMC Cardiovascular Disorders. March 2022. [Accessed on 27th June 2026]

4. Bricout-Hennel. S, Zelveian. P, Nedogoda. S, Safety and efficacy of indapamide sustained release/amlodipine fixed-dose combination in essential hypertension. Journal of Hypertension. June 2018. [Accessed on 27th June 2026]

5. Pfizer Labs. Food & Drug Administration. [Revised in May 2011] [Accessed on 27th June 2026]

Useful Diagnostic Tests

• Kidney Function Test

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)

Last updated on 30 Jun 2026 | 10:44 AM(IST)