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Introduction About IMFERON INJECTION
IMFERON INJECTION contains Iron Dextran which belongs to the group of medicines called Iron preparations. IMFERON INJECTION is used to manage iron deficiency in patients who cannot take iron by mouth or when iron taken by mouth (by patients) becomes ineffective.
IMFERON INJECTION is not recommended for use in patients allergic to Iron dextran, and/or other medicines. It is also not recommended for use in patients suffering from anaemia (not caused by low iron levels), and in patients who have excess iron production in the body. The medicine is also indicated for use in patients suffering from bacterial/viral infection, liver problems (such as cirrhosis, hepatitis), and/or kidney problems (such as acute kidney failure).
Before receiving IMFERON INJECTION, inform your doctor if you suffer from systemic lupus erythematosus (inflammatory disease), rheumatoid arthritis (chronic inflammatory disease affecting joints), eczema (skin inflammation), and/or lung problems (such as asthma).
IMFERON INJECTION should be used with caution during pregnancy and in women planning for pregnancy only if it is clearly necessary. It is also advised to be used with caution in breastfeeding women.
IMFERON INJECTION is not recommended for use in children and adolescents (aged below 14 years) and is advised to be used with caution in elderly patients (aged 65 years and above) after consulting your doctor.
The most common side effects of receiving IMFERON INJECTION are nausea, vomiting, diarrhoea, headache, fever, chills, and/or backache. Consult your doctor if any of these symptoms worsens.
Uses Of IMFERON INJECTION
- Manages iron deficiency in affected individuals
How IMFERON INJECTION Works
IMFERON INJECTION works by restoring iron in the iron stores (in body) which helps to produce red blood cells. Iron is generally delivered to the bone marrow for haemoglobin production by transferrin glycoprotein which leads to production of new red blood cells thus managing iron deficiency in affected individuals.
How to use IMFERON INJECTION
IMFERON INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion or into a muscle as an intramuscular injection. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of IMFERON INJECTION
Common
- nausea, vomiting, diarrhoea
- headache
- fever, chills
- backache
Uncommon
- abdominal pain
- blurred vision
- feeling hot
- cramps
- numbness
Rare
- loss of consciousness, altered mental status, dizziness, restlessness, fatigue
- seizure (fits)
- low blood pressure
- angioedema (severe allergic reaction)
- uneven/irregular heartbeat, high pulse rate, chest pain
- sweating
- tremor
Stop receiving IMFERON INJECTION and contact your doctor immediately if you experience any of the following side effects:
- serious allergic reaction such as Kounis syndrome associated with symptoms such as shortness of breath, nettle rash/hives, flushing, rashes, itching, nausea, shivering, and/or chest pain.
- signs of anaphylactic reactions (severe, potentially life-threatening allergic reaction) such as red itchy welts, pale skin, low blood pressure, difficulty in breathing, and/or dizziness
How To Manage Side Effects
Nausea and vomiting:
Take IMFERON INJECTION with/just after a meal. Stick to simple meals. Avoid eating oil rich/spicy foods, sugary snacks and drinks. Avoid drinking too much liquid along with your meals, and drink slowly in between meals. Consult your doctor if the condition worsens.
Diarrhea:
Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult and inform your doctor if the symptom worsens.
Headache:
If IMFERON INJECTION causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of receiving IMFERON INJECTION. If it lasts more than a week or becomes severe, then consult and inform your doctor.
Warning & Precautions
Pregnancy
IMFERON INJECTION should be used with caution during pregnancy and in women planning for pregnancy only if it is clearly necessary. Consult your doctor before receiving IMFERON INJECTION.
Breastfeeding
IMFERON INJECTION should be used with caution in breastfeeding women. Consult your doctor before receiving IMFERON INJECTION.
Driving and Using Machines
Do not drive/operate machines if IMFERON INJECTION affects your ability to drive or operate machines.
Kidney
IMFERON INJECTION is not recommended for use in patients with kidney problems such as acute kidney failure. Consult your doctor before taking this medication.
Liver
IMFERON INJECTION is not recommended for use in patients with liver problems such as cirrhosis, hepatitis. Consult your doctor before receiving IMFERON INJECTION.
Allergy
IMFERON INJECTION is not recommended for use if you are allergic (hypersensitive) to Iron dextran, other medicines, and/or any other ingredients of this medicine.
Lungs
IMFERON INJECTION should be received with caution in patients with lung problems such as asthma. Consult your doctor before receiving the medicine.
Others
IMFERON INJECTION is not recommended for use if you:
- suffer from anaemia that is not caused by low levels of iron (deficiency) such as haemolytic anaemia
- have excess iron in the body
- have bacterial/viral infection.
Before receiving IMFERON INJECTION, inform your doctor if you:
- have systemic lupus erythematosus (inflammatory disease)
- have rheumatoid arthritis (chronic inflammatory disease affecting joints)
- suffer from eczema (skin inflammation)
Use in Paediatrics:
IMFERON INJECTION is not recommended for use in children and adolescents (aged below 14 years). Consult your doctor before receiving the medicine.
Use in Geriatrics:
IMFERON INJECTION should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before receiving the medication.
Interactions
A. Drug - Drug interactions:
Before receiving IMFERON INJECTION, inform your doctor if you are receiving any of the following medicine:
- vitamins and minerals (oral supplements)
- other oral iron supplements
Overdosage:
IMFERON INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms.
Synopsis
| Drug | : | Iron Dextran |
| Pharmacological Category | : | Iron preparations |
| Therapeutic Indication | : | Iron deficiency |
| Dosage Forms | : | Injection |
More Information
- Keep IMFERON INJECTION out of reach of children
- Store IMFERON INJECTION at room temperature
FAQs About IMFERON INJECTION
Q. What is IMFERON INJECTION used for?
A. IMFERON INJECTION is used to manage iron deficiency in patients who cannot take iron by mouth or when iron taken by mouth (by patients) becomes ineffective.
Q. What are the common side effects of taking IMFERON INJECTION?
A. The most common side effects of receiving IMFERON INJECTION are nausea, vomiting, diarrhoea, headache, fever, chills, and/or backache. Consult your doctor if any of these symptoms worsens.
Q. How is IMFERON INJECTION administered?
A. IMFERON INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion or into a muscle as an intramuscular injection. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Q. What happens if IMFERON INJECTION is administered more than its required dosage?
A. IMFERON INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms.
Q. How IMFERON INJECTION works?
A. IMFERON INJECTION works by restoring iron in the iron stores (in body) which helps to produce red blood cells. Iron is generally delivered to the bone marrow for haemoglobin production by transferrin glycoprotein which leads to production of new red blood cells thus managing iron deficiency in affected individuals.
References
1. K.D. Tripathi. Haematinics and Erythropoietin. Essentials of medical pharmacology. Seventh edition. 2013. Page – 604.
2. Iron Dextran. NIH National Library of Medicine. National center for biotechnology information. PubChem. March 2022. [Accessed on 12th March 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Iron-dextran#section=Biological-Half-Life
3. Pharmacosmos A/S. Electronic Medicines Compendium (EMC). [Revised in January 2020] [Accessed on 12th March 2022] https://www.medicines.org.uk/emc/product/48/smpc https://www.medicines.org.uk/emc/files/pil.48.pdf
4. C M Reddy, S K Kathula, S A Ali, R Bekal, M Walsh. Safety and efficacy of total dose infusion of iron dextran in iron deficiency anemia. NIH National Library of Medicine. National center for biotechnology information. PubMed.gov. March 2008. [Accessed on 12thMarch 2022] https://pubmed.ncbi.nlm.nih.gov/18005041/
Useful Diagnostic Tests
- Ferritin test
- Complete blood count test
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