HIFENAC SP Tablet 10's

Introduction About HIFENAC SP TABLET

Hifenac SP Tablet is a commonly prescribed medicine that contains a combination of Aceclofenac, Paracetamol, and Serratiopeptidase. It is often included in care plans where individuals experience pain, swelling, inflammation, or discomfort related to muscle injuries, joint conditions, dental procedures, or post-surgical recovery. This medicine helps by reducing pain signals, lowering inflammation, and supporting the reduction of swelling around affected tissues.  

Hifenac SP Tablet is usually recommended for people dealing with musculoskeletal pain, arthritis-related discomfort, joint stiffness, back pain, or swelling after injury or surgery. It may also be beneficial in improving comfort during movement and reducing inflammation-related discomfort that affects daily activities. The tablet is generally taken once or twice a day, preferably after meals, as taking it with food or milk may help reduce stomach irritation.  

While taking Hifenac SP Tablet, patients are advised to follow a fixed dosing schedule and avoid taking extra doses without medical advice. Common precautions include staying hydrated, avoiding alcohol, and being cautious while driving if dizziness or drowsiness occurs. Individuals with stomach ulcers, liver disease, kidney problems, or heart conditions should inform their doctor before using this medicine. Monitoring may also be needed if taken along with blood thinners, other painkillers, or medicines for blood pressure.

Use of Hifenac SP Tablet in pregnancy and breastfeeding should only be considered under medical supervision. Some commonly observed side effects may include nausea, stomach pain, indigestion, dizziness, drowsiness, or diarrhoea. If these symptoms persist or worsen, a healthcare provider should be consulted for advice. This medicine is part of a carefully managed care plan, and patients are encouraged to maintain good hydration, balanced meals, and light physical activity to support better results during its use.  

Uses Of HIFENAC SP TABLET

•  Reduce pain and inflammation associated with arthritis, joint pain, and muscle stiffness
•  Manage swelling and discomfort after surgery, dental procedures, or soft tissue injury

Benefits of HIFENAC SP TABLET

Hifenac SP for Joint Pain and Stiffness

Hifenac SP Tablet may be advised to help reduce joint pain and stiffness linked to arthritis or inflammatory conditions. It works by reducing the chemical messengers responsible for pain and swelling. This helps improve flexibility and ease difficulty in movement, especially when stiffness affects daily tasks like walking, bending, or climbing stairs.

Hifenac SP for Swelling and Inflammation

In some cases, Hifenac SP is used when individuals experience swelling after surgery, injury, or dental procedures. Serratiopeptidase in the medicine helps reduce fluid buildup and tissue swelling. This action supports smoother healing and helps relieve discomfort caused by inflammation in affected areas.

Hifenac SP for Muscle and Back Pain

Hifenac SP Tablet may be included in pain management routines to support better comfort in people with muscle strain, back pain, or soft tissue injuries. It helps by relaxing inflammation-related tension and reducing pain signals from injured areas. As discomfort improves, patients may find better mobility and improved physical activity during daily routines.

How HIFENAC SP TABLET Works

Hifenac SP Mechanism of Action

Hifenac SP Tablet contains Aceclofenac, Paracetamol, and Serratiopeptidase. Aceclofenac belongs to the class of medicines called non-steroidal anti-inflammatory drugs (NSAIDs), while Paracetamol acts as a pain reliever and fever reducer. Serratiopeptidase is an enzyme that helps reduce swelling. Together, they work by blocking pain-causing chemical messengers and supporting recovery from inflammation.

Role of Hifenac SP in Pain Relief

Hifenac SP Tablet is often included in care plans where individuals experience pain due to arthritis, injury, or surgery. It supports pain control by reducing inflammation and easing tissue swelling. This can lead to improved comfort and better physical function during routine daily activities.

Hifenac SP Effect on Swelling and Recovery

Hifenac SP Tablet influences the body’s inflammatory response by controlling pain signals and reducing abnormal protein buildup at the site of swelling. As a result, users may notice reduced puffiness, less stiffness, and improved healing support. This effect can be especially useful in post-operative care and musculoskeletal recovery.

How to use HIFENAC SP TABLET

How to Take Hifenac SP Tablet
 

• Take Hifenac SP Tablet exactly as advised by your doctor
•  Swallow the tablet whole with a glass of water
•  Take it preferably after meals to reduce stomach discomfort
•  Do not crush, chew, or break the tablet
•  Take it at the same time each day for better results
•  Never change your dose or stop taking it without consulting your healthcare provider

What if I forgot to take HIFENAC SP TABLET

• Take it as soon as you remember, if it is not too close to your next scheduled dose
• Skip the missed dose if it is almost time for the next one do not double the dose
•  Continue with your regular dosing schedule as advised
•  Missing doses regularly may reduce the medicine’s effectiveness
•  If you are unsure what to do, speak with your doctor or pharmacist
•  To avoid missing future doses, set a daily reminder or alarm

Overdose

If you or anyone accidentally takes too much Hifenac SP Tablet, consult your doctor immediately or visit the nearest hospital. Overdose symptoms may include headache, nausea, vomiting, stomach pain, diarrhoea, dizziness, drowsiness, low blood pressure, breathing difficulty, fainting, seizures, or stomach bleeding.

Side Effects Of HIFENAC SP TABLET

Common side effects of Hifenac SP Tablet:

•  nausea
•  vomiting
•  stomach pain
•  indigestion
•  diarrhoea
•  dizziness
•  drowsiness
•  loss of appetite
•  skin rash
• increased liver enzymes

When to Seek Medical Attention?

Stop taking Hifenac SP Tablet and contact your doctor if you experience any of the following side effects

• Signs of serious skin reactions (exfoliative dermatitis, Stevens-Johnson syndrome, and toxic epidermal necrolysis) such as skin rash and mucosal lesions

How To Manage Side Effects

Dizziness Or Drowsiness

• Stay well-hydrated: Drink enough water throughout the day. Dehydration is one of the most common causes of dizziness.
• Eat regular meals: Low blood sugar can trigger dizziness, so avoid skipping meals and include healthy snacks like fruits or nuts.
• Sit or lie down immediately: If you feel dizzy, rest in a comfortable position to prevent falls or injuries.
• Take slow, deep breaths: This helps improve oxygen flow and reduces dizziness caused by anxiety or stress.
• Have an electrolyte-rich drink: Coconut water or oral rehydration solutions can help restore salt and mineral balance.
• Use a cool compress: Applying a damp, cool cloth to your forehead may help calm dizziness.
• Practice balance exercises: Gentle movements like yoga or tai chi can help improve body coordination over time.
• Avoid sudden movements: Stand up slowly from sitting or lying positions to prevent a sudden drop in blood pressure.

Nausea And Vomiting

• Ginger: Ginger tea, ginger water, or a small piece of fresh ginger can help calm the stomach and reduce the urge to vomit.
• Lemon: Sipping warm lemon water or smelling fresh lemon may help ease nausea and freshen the stomach.
• Mint (Pudina): Mint tea or chewing fresh mint leaves may help soothe the stomach and reduce queasiness.
• Cold Water or Ice Chips: Taking small sips of cold water or sucking on ice chips can help reduce nausea.
• Fennel Seeds (Saunf): Chewing fennel seeds or drinking fennel seed water may help relieve nausea and bloating.
• Clove: Sucking on a clove or drinking clove tea can help reduce the uneasy feeling in the stomach.

Warning & Precautions

Pregnancy

Contraindicated

Hifenac SP Tablet is not recommended for use during pregnancy. Please consult your doctor before taking this medicine.

Breastfeeding

Contraindicated

Hifenac SP Tablet is not recommended for breastfeeding women, as it may pass into breast milk. Consult your doctor before use.

Driving and Using Machines

Use with Caution

Avoid driving or operating machines if you feel dizzy after taking Hifenac SP Tablet.

Alcohol

Contraindicated

Avoid alcohol while taking Hifenac SP Tablet, as it may increase the risk of liver damage.

Kidney

Contraindicated

Hifenac SP Tablet is not recommended for patients with moderate to severe kidney problems. Consult your doctor before use.

Liver

Consult your doctor

Hifenac SP Tablet is not recommended for patients with severe liver problems. It should be used carefully in mild to moderate liver disease or hepatic porphyria. Consult your doctor before taking it.

Allergy

Contraindicated

Do not take Hifenac SP Tablet if you are allergic to Aceclofenac, Paracetamol, Serratiopeptidase, or any of its ingredients.

Lungs

Use with Caution

Use Hifenac SP Tablet with caution if you have asthma or a history of bronchial asthma. Consult your doctor before use.

Heart Disease

Consult your doctor

Hifenac SP Tablet is not recommended for patients with severe heart disease. It should be used carefully in mild to moderate heart conditions such as heart failure, ischaemic heart disease, or circulation problems. Consult your doctor before use.

Use In Pediatrics

Contraindicated

Hifenac SP Tablet is not recommended for children and adolescents below 18 years of age. Consult your doctor before taking it. 

Use In Geriatrics

Use with Caution

Hifenac SP Tablet should be used with caution in elderly patients. Consult your doctor before taking it.

Other Warnings for HIFENAC SP TABLET

Before taking Hifenac SP Tablet, inform your doctor if you

• Have uncontrolled high blood pressure
• Have diabetes
• Are a smoker
• Suffer from hyperlipidaemia
• Have gastrointestinal bleeding, ulceration, or perforation
• Have gastrointestinal diseases such as ulcerative colitis (inflammatory bowel disease)
• Have systemic lupus erythematosus (autoimmune disorder)
• Have mixed connective tissue disorders such as scleroderma and polymyositis
• Have aseptic meningitis (inflammation of the brain)
• Have bleeding disorders such as haemophilia, von Willebrand disease
• Have signs of cerebrovascular bleeding, such as sudden, severe headaches or seizures
• Are on diuretic therapy

Who should not take HIFENAC SP TABLET

Hifenac SP Tablet is not recommended for use if you

• Have a history of or an active, recurrent peptic ulcer or haemorrhage (bleeding)
• Have previously shown hypersensitive reactions to ibuprofen, aspirin, or other NSAIDs   
• Have a previous history of an anaphylactic reaction
• Suffer from severe hypertension (high blood pressure)

Safety Advice

• Take only as prescribed and do not exceed the recommended dose
•  Prefer taking the tablet after meals to reduce stomach irritation
•  Avoid alcohol, as it may increase the risk of liver damage and stomach bleeding
•  Inform your doctor if you have kidney, liver, heart, or stomach-related problems
•  Use caution if you have asthma or a history of ulcers or bleeding disorders
•  Do not combine with other painkillers unless advised by your doctor
•  Stay hydrated and report unusual symptoms like severe stomach pain, black stools, or persistent dizziness
•  Regular follow-ups may be needed if used for a longer duration

Diet and Lifestyle Advice

• Take Hifenac SP Tablet after meals to help reduce stomach irritation and improve comfort
•  Drink plenty of water throughout the day to stay hydrated and support recovery
•  Eat light, balanced meals and avoid very spicy, oily, or heavy foods if you experience stomach discomfort
•  Include fibre-rich foods like fruits, vegetables, and whole grains to support digestion
•  Avoid alcohol, as it may increase the risk of liver problems and stomach irritation
•  Limit caffeine if it worsens acidity or stomach discomfort
•  Follow gentle physical activity like walking or stretching to support joint and muscle flexibility
•  Get enough rest to help the body recover from pain, swelling, or inflammation
•  Maintain a healthy weight to reduce stress on joints and musclesTop of Form

1.Hifenac SP Tablet vs Flexon Tablet

Drug - Drug interaction

1. Blood Thinners (e.g., Warfarin, Aspirin, Clopidogrel)

• Interaction: Taking Hifenac SP with blood thinners may increase the risk of bleeding, especially in the stomach or intestines.
•  Management: Use only under medical supervision. Regular monitoring for signs of bleeding such as black stools, unusual bruising, or vomiting blood is important.

2. Other Painkillers / NSAIDs (e.g., Ibuprofen, Diclofenac, Naproxen)

•  Interaction: Combining with other painkillers may increase the risk of stomach ulcers, bleeding, and kidney problems.
•  Management: Avoid taking multiple painkillers together unless advised by your doctor. Follow the prescribed dose carefully.

3. Blood Pressure Medicines (e.g., Amlodipine, Enalapril, Losartan)

•  Interaction: Hifenac SP may reduce the effectiveness of blood pressure medicines and may increase the risk of kidney problems.
•  Management: Blood pressure and kidney function should be monitored regularly. Drink enough fluids and inform your doctor if swelling occurs.

4. Diuretics (e.g., Furosemide, Hydrochlorothiazide)

•  Interaction: This combination may reduce the effect of diuretics and increase the chances of dehydration or kidney strain.
•  Management: Doctors may monitor kidney function and advise proper hydration. Dose adjustments may be needed.

5. Corticosteroids (e.g., Prednisolone, Dexamethasone)

•  Interaction: Using both together may raise the risk of stomach irritation, ulcers, or gastrointestinal bleeding.
•  Management: Take after food and report symptoms like severe stomach pain or black stools immediately.

6. Methotrexate

•  Interaction: Hifenac SP may increase methotrexate levels in the body, raising the risk of toxicity and side effects.
•  Management: Close monitoring is required. Your doctor may adjust the dose or timing of both medicines.

7. Anti-diabetic Medicines (e.g., Metformin, Glimepiride)

•  Interaction: Hifenac SP may affect blood sugar control in some patients.
•  Management: Monitor blood sugar levels regularly and inform your doctor if unusual weakness, sweating, or dizziness occurs.

Drug - Food interaction

1. Spicy and Oily Foods

•  Interaction: Heavy, spicy, or oily foods may worsen stomach irritation, acidity, or indigestion while using this medicine.
•  Management: Prefer light, balanced meals and avoid foods that trigger stomach discomfort.

2. High-Fat Meals

•  Interaction: Very heavy or fatty meals may slow down the absorption of the medicine and delay its pain-relieving effect.
•  Management: Take the tablet after normal meals rather than very heavy meals for better tolerance and timely action.

3. Caffeinated Beverages (Coffee, Tea, Cola)

•  Interaction: Excess caffeine may worsen acidity, stomach discomfort, or nervousness in some individuals.
•  Management: Limit caffeine intake and choose water, fresh juices, or light herbal drinks when possible.

4. Low-Water Intake

•  Interaction: Poor hydration may increase the chances of dizziness, kidney strain, and reduced overall tolerance of the medicine.
•  Management: Drink plenty of water throughout the day unless your doctor has advised fluid restriction.

5. Low-Fiber Diet

•  Interaction: A low-fibre diet may worsen digestion issues such as bloating or constipation during medicine use.
•  Management: Include fruits, vegetables, and whole grains in your meals to support healthy digestion.

6. Grapefruit Juice

•  Interaction: In some cases, grapefruit juice may affect how certain medicines are processed in the body and may increase unwanted effects.
•  Management: It is better to avoid grapefruit juice unless your doctor specifically advises it is safe for you.

Synopsis

More Information

FAQs About HIFENAC SP TABLET

References

1.Karthikeyan Murthykumar, Arvina Rajasekar, and Gurumoorthy Kaarthikeyan. Analgesics/Anti-Inflammatory Drugs Preferred Following Implant Placement: A Retrospective Study. NIH National Library of Medicine. National centre for biotechnology information. PMC PubMed Central. [Accessed on 7th May 2026]

Author Details

Written By Dr. R. Dinesh John Rajkumar - Pharm.D

Reviewed For Accuracy By Dr. Sankara Babu Gorle - MBBS, MD (Pharmacology)

Last updated on 07 May 2026 | 03:41 PM(IST)