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Introduction About HEXIMETRO MOUTH GEL
HEXIMETRO MOUTH GEL is a combination of Chlorhexidine, Metronidazole and Lignocaine which belong to the groups of medicines called Antiseptic Antibacterial agents, Nitroimidazoles and Local Anesthetics, respectively. HEXIMETRO MOUTH GEL is used to manage halitosis, gingivitis, oral stomatitis, pain due to mouth ulcers and food burns. It is also used to manage plaque growth on the teeth.
Halitosis is a condition that occurs due to trapped bacteria on the uneven microscopic surface of the tongue that produces odours, contributing to bad breath in an individual. Gingivitis is a form of gum disease that occurs due to poor hygiene and is generally characterised by symptoms such as swollen and receding gums.
Oral stomatitis is a condition characterised by painful swelling and sores inside the mouth that occur due to an infection, an allergic reaction or irritating foods. Mouth ulcers are small lesions that develop in your mouth or at the base of your gums, which make eating and drinking uncomfortable.
HEXIMETRO MOUTH GEL is not recommended for use in patients who are allergic to chlorhexidine or metronidazole. lignocaine, methyl hydroxybenzoate, propyl hydroxybenzoate or para-aminobenzoic acid. Before applying HEXIMETRO MOUTH GEL, inform your doctor if you have traumatised (injured) mucosa, sepsis (a life-threatening infection) in the application site, poor general health, severe liver disease and renal dysfunction and/or a partial or complete heart block.
HEXIMETRO MOUTH GEL should be used with caution during pregnancy and only if necessary, in breastfeeding women. HEXIMETRO MOUTH GEL is not recommended for use by children (below 12 years of age). The most common symptoms of applying HEXIMETRO MOUTH GEL are dry mouth, altered taste sensations (such as metallic taste), discoloured or coated tongue, nausea, vomiting and abdominal discomfort. Consult your doctor if any of these symptoms get worse.
Uses Of HEXIMETRO MOUTH GEL
- Manage halitosis, gingivitis, oral stomatitis, pain due to mouth ulcers and food burns
- Prevents plaque growth on the teeth
How HEXIMETRO MOUTH GEL Works
HEXIMETRO MOUTH GEL helps to manage mouth ulcers, halitosis, gingivitis and oral stomatitis and manages plaque growth. Chlorhexidine heals ulcers by decreasing the number of bacteria in the mouth, leading to decreased swelling and redness of the gums, Metronidazole kills bacteria or other microorganisms by damaging their DNA and Lignocaine provides relief from painful mouth sores by forming a protective coating over the mouth sores and blocking their pain signals.
How to use HEXIMETRO MOUTH GEL
Always apply HEXIMETRO MOUTH GEL, as directed by your physician. It is for external use only. On the affected area, apply a thin layer of this medicine. Managed areas on the face need not be covered with a plaster or bandage. Do not apply HEXIMETRO MOUTH GEL to your face beyond 5 days. Avoid applying HEXIMETRO MOUTH GEL around your eyes, including your eyelids.
Side Effects Of HEXIMETRO MOUTH GEL
Common
- dry mouth
- altered taste sensations such as metallic taste
- discolored or coated tongue
- nausea
- vomiting
- abdominal discomfort
- diarrhea
Uncommon
- burning sensations
- oral mucosal peeling
- swelling of the parotid gland (the salivary gland that produces saliva)
- oral paraesthesia (prickling or tickling sensation)
Rare
Stop applying HEXIMETRO MOUTH GEL and contact your doctor if you experience any of the following side effects:
- signs of severe allergic reaction such as difficulty while breathing, rash, swelling of lips, tongue, throat or face
- soreness, irritation or swelling of the mouth
How To Manage Side Effects
Dry mouth:
Try to drink plenty of cold water and sip on cold, unsweetened drinks and use lip balm if your lips are dry. Brush your teeth twice a day and use mouthwash. Consult and inform your doctor if the symptom gets worse.
Nausea and vomiting:
Try to take HEXIMETRO MOUTH GEL with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom gets worse.
Diarrhoea:
Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhoea. Consult your doctor and inform them if the symptom gets worse.
Warning & Precautions
Pregnancy
HEXIMETRO MOUTH GEL should be used with caution during pregnancy only if it is necessary. Consult your doctor before applying the medicine.
Breastfeeding
HEXIMETRO MOUTH GEL should be used with caution in breastfeeding women only if it is necessary. Consult your doctor before applying for the medicine.
Driving and Using Machines
Do not drive or operate machines while applying HEXIMETRO MOUTH GEL since it may temporarily affect your ability to drive or operate machines.
Kidney
HEXIMETRO MOUTH GEL should be used with caution in patients with severe renal dysfunction. Consult your doctor before applying for the medicine.
Liver
HEXIMETRO MOUTH GEL should be used with caution in patients with advanced liver disease. Consult your doctor before applying for the medicine.
Allergy
HEXIMETRO MOUTH GEL is not recommended for use if you are allergic to chlorhexidine or metronidazole. lignocaine, methyl hydroxybenzoate, propyl hydroxybenzoate, para amino benzoic acid or any other ingredients of this medicine.
Heart Disease
HEXIMETRO MOUTH GEL should be used with caution in patients with heart diseases such as partial or complete heart block. Consult your doctor before applying for the medicine.
Others
Before applying HEXIMETRO MOUTH GEL, inform your doctor if you:
- have traumatized (injured) mucosa
- have sepsis (a life-threatening complication of an infection) in the region of the proposed application
- have a poor general health
Use in Pediatrics:
HEXIMETRO MOUTH GEL is not generally not recommended for use in children (below 12 years of age) unless considered necessary. It should be used with caution in children and adolescents (from 12 to 18 years of age). Consult your doctor before applying HEXIMETRO MOUTH GEL.
Use in Geriatrics:
HEXIMETRO MOUTH GEL should be applied with caution in elderly patients (aged 65 years or above). Consult your doctor before applying HEXIMETRO MOUTH GEL.
Interactions
A. Drug-Drug Interactions:
Before applying HEXIMETRO MOUTH GEL, inform your doctor, if you are applying any of the following medicine:
- anticoagulants (used to manage blood clots) such as coumarin derivatives (Ex. warfarin)
- anti-arrhythmic drugs (used to manage a heart rhythm that's too fast or irregular) Ex. amiodarone
- cimetidine (used to manage stomach ulcers)
- beta-blockers (used to manage high blood pressure)
- general anesthesia (used to induce unconsciousness during surgery) Ex. propofol, ketamine
- benzodiazepine, barbiturate (used to manage anxiety and insomnia)
Overdosage:
If you or anyone else applies too much of HEXIMETRO MOUTH GEL or accidentally swallows it, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are circumoral paraesthesia (burning, prickling or itching sensation), numbness of the tongue, light-headedness, hyperacusis (unusual tolerance to ordinary environmental sounds), ringing in the ears, visual disturbance, muscular tremors, generalized & grand mal convulsions (seizures), unconsciousness, hypoxia (low oxygen level), hypercarbia (increased carbon-di-oxide in the blood), apnoea (serious sleep disorder), severe low blood pressure, slow heart rate, irregular heartbeat, arrhythmia and cardiovascular collapse.
Synopsis
| Drug | : | Chlorhexidine, Metronidazole, Lignocaine |
| Pharmacological Category | : | Antiseptic Antibacterial agents, Nitroimidazoles and Local Anaesthetics |
| Therapeutic Indication | : | Halitosis, Gingivitis, Plaque, Oral stomatitis, pain due to mouth ulcer and food burns |
| Dosage Forms | : | Gel |
More Information
- Keep HEXIMETRO MOUTH GEL out of reach from children
- Store HEXIMETRO MOUTH GEL at room temperature
FAQs About HEXIMETRO MOUTH GEL
Q: What is the function of HEXIMETRO MOUTH GEL?
A: HEXIMETRO MOUTH GEL is used to manage halitosis, gingivitis, oral stomatitis, pain due to mouth ulcers and food burns. It is also used to manage plaque growth on the teeth.
Q: Is HEXIMETRO MOUTH GEL safe to be used by children?
A: HEXIMETRO MOUTH GEL is generally not recommended for use in children (those under the age of 12) unless necessary. It should be used with caution in children and adolescents (from 12 to 18 years of age). Consult your doctor before applying HEXIMETRO MOUTH GEL.
Q: Who should avoid applying HEXIMETRO MOUTH GEL?
A: HEXIMETRO MOUTH GEL is not recommended for use in patients who are allergic to chlorhexidine or metronidazole or lignocaine, methyl hydroxybenzoate, propyl hydroxybenzoate or para-aminobenzoic acid. It is also not recommended for use in children under the age of 12 unless necessary. Consult your doctor before applying for the medicine.
Q: Is HEXIMETRO MOUTH GEL safe to be used by pregnant and breastfeeding women?
A: HEXIMETRO MOUTH GEL should only be used in pregnant or breastfeeding women if necessary. Consult and inform your doctor before applying for the medicine.
Q: How does HEXIMETRO MOUTH GEL work?
A: HEXIMETRO MOUTH GEL helps to manage mouth ulcers, halitosis, gingivitis and oral stomatitis and manages plaque growth. Chlorhexidine heals ulcers by decreasing the number of bacteria in the mouth, leading to decreased swelling and redness of the gums. Metronidazole kills bacteria or other microorganisms by damaging their DNA.
References
1. KD Tripathi. Local Anaesthetics, Antiamoebic & Other Antiprotozoal Drugs, and Antiseptics, Disinfectants & Ectoparasiticides. Essentials of medical pharmacology. Seventh edition. 2013. Page – 366, 837, 900.
2. Arthiie Thangavelu, Sahaya Stelin Kaspar, Ramesh Periannan Kathirvelu, Bhuvaneshwari Srinivasan, Soundarya Srinivasan, and Rajasekar Sundram. Chlorhexidine: An Elixir for Periodontics. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in August 2020] [Accessed on 19th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595540/
3. Connor B. Weir; Jacqueline K. Le. Metronidazole. NIH National Library of Medicine. National Center for Biotechnology Information. StatPearls [Internet]. [Revised in April 2022] [Accessed on 19th July 2022] https://www.ncbi.nlm.nih.gov/books/NBK539728/
4. Gabriel B. Beecham, Trevor A. Nessel, Amandeep Goyal. Lidocaine. NIH National Library of Medicine. National Center for Biotechnology Information. StatPearls [Internet]. [Revised in December 2021] [Accessed on 19th July 2022] https://www.ncbi.nlm.nih.gov/books/NBK539881/
5. Purna Pharmaceuticals NV. Electronic Medicines Compendium (EMC). [Revised in May 2020] [Accessed on 19th July 2022] https://www.medicines.org.uk/emc/files/pil.21.pdf
6. Galderma Production Canada, Inc. Food & Drug Administration (FDA). [Accessed on 19th July 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/021789lbl.pdf
7. Pharmacy Retailing (NZ) Limited. MEDSAFE - New Zealand Medicines and Medical Devices Safety Authority. [Revised in January 2018] [Accessed on 19th July 2022] https://www.medsafe.govt.nz/profs/Datasheet/x/Xylocainejelly.pdf
8. Agrawal Drugs Pvt. Limited. Notty Gel. [Accessed on 19th July 2022] https://www.adplindia.in/product/notty-gel/
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