This test detects the presence of herpes simplex virus (HSV) DNA in the body. HSV includes two types: HSV-1, usually causing oral infections (like cold sores), and HSV-2, mainly causing genital infections. The test identifies if either type is present by looking for viral DNA in a sample, helping to confirm an infection, especially when symptoms like blisters or sores appear. It provides important information for diagnosis and treatment decisions and can also help detect herpes infection in newborns or people with suspected viral infections affecting the brain.

What it Measures:

The Herpes Simplex Virus DNA PCR qualitative test uses a method called polymerase chain reaction (PCR) to find the genetic material (DNA) of the herpes virus in the body. This test is very sensitive and can detect even small amounts of the virus. It measures:

HSV-1 DNA: This indicates infection with Herpes Simplex Virus Type 1, commonly associated with oral herpes (cold sores).
HSV-2 DNA: This indicates infection with Herpes Simplex Virus Type 2, usually linked to genital herpes.

The test does not measure how severe the infection is but confirms if the virus’s DNA is present, meaning an active or recent infection or viral shedding. It is more accurate than other tests like cultures, especially in early or difficult-to-diagnose cases such as newborn infection or symptoms affecting the brain. The sample can be blood, skin or genital swabs, or other body fluids depending on where symptoms appear.

Why is it Important:

Accurate Diagnosis: Differentiating HSV-1 and HSV-2 guides appropriate care since both cause herpes but may require different clinical management.
Early Detection: It helps catch herpes infection even if sores are not visible, allowing timely treatment and reducing spread.
Monitoring in Pregnant Women: Detects infection risk to newborn babies, helping doctors manage pregnancy and delivery safely.
Helps in Complex Illness: Useful for diagnosing viral brain infections (encephalitis) caused by HSV, which need urgent treatment.
Guides Prevention: Knowing the virus type helps patients take precautions to avoid infecting others and manage outbreaks better.

When Should I Get This Test?

When you experience painful blisters or sores around the mouth, genitals, or other body parts.
If you have symptoms suggestive of viral brain infection like fever, headache, or confusion.
If you are pregnant and suspect herpes infection to protect your baby.
After exposure to someone diagnosed with HSV to check infection status.
If you have repeated unexplained sores or symptoms suspected to be herpes related.

Interpretation of Test Results:

Understanding what your results might mean is helpful, but always discuss them with a doctor for a proper diagnosis.

Result Type	What it Means
Negative	No HSV DNA detected; unlikely current herpes infection
Positive for HSV-1	HSV-1 DNA found, indicates infection with HSV-1 virus
Positive for HSV-2	HSV-2 DNA found, indicates infection with HSV-2 virus
Indeterminate/Borderline	Low levels detected; repeat test or clinical correlation needed

(Note: Specific normal ranges and interpretation can vary slightly between labs and individual factors. Always refer to the ranges on your report and consult your doctor.)

Additional Information:

This test detects active viral DNA but does not measure antibody levels (past exposure).
A negative result does not fully rule out herpes if symptoms exist; your doctor may recommend other tests.
Always consult healthcare providers for treatment advice and to prevent transmission.

Test Requirements:

Sample type: Blood or swab from lesion or relevant site, as advised by the doctor.
No fasting required before the test.
Avoid touching or irritating sores before sample collection to prevent contamination.

FAQs:

Do I need to fast before the Herpes Simplex Virus DNA PCR test?
No fasting is needed for this test. You can eat and drink normally before sample collection. Staying hydrated is recommended for easier blood draw.
Can pregnancy affect Herpes Simplex Virus test results?
Pregnancy itself doesn't change test results, but testing is important to protect the baby from infection during delivery. If results are positive, your doctor will advise on safe management.
What should I do if my test result is positive?
A positive result means herpes virus is detected. It's important to consult your doctor for advice on treatment, preventing spread, and follow-up care.
Can this test detect herpes if there are no symptoms?
Yes, the PCR test is very sensitive and can detect HSV DNA even when you don’t have visible sores, helping in early diagnosis.
Is this test different from antibody tests for herpes?
Yes, this test looks for the virus's DNA to identify an active infection, while antibody tests check past exposure. Both tests provide different information your doctor may use.

For more information, see Netmeds Health Library blog: Herpes Is Incurable, Prevention Is The Key

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Reports

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Customers