GRILINCTUS Syrup 100ml

Introduction About GRILINCTUS SYRUP

GRILINCTUS SYRUP is combination of Chlorpheniramine maleate, Dextromethorphan hydrobromide, Guaiphenesin, and Ammonium chloride which belongs to the group of medicines called Antihistamines, Antitussives, and Expectorants, respectively. It is used to provide relief from cough and symptoms of upper respiratory tract which includes nasal congestion associated with allergy/common cold in affected individuals.

GRILINCTUS SYRUP is not recommended for use if you are allergic to chlorpheniramine maleate, dextromethorphan hydrobromide, guaiphenesin, and/or ammonium chloride. It is also not recommended for use in patients with heart diseases (such as ventricular tachycardia, severe coronary disease), lung diseases (such as chronic bronchitis, asthma), and/or severe rise in blood pressure.

Before taking GRILINCTUS SYRUP, inform your doctor if you have diabetes, intolerance to certain sugars, kidney diseases (such as acute renal injury), and/or liver diseases.

GRILINCTUS SYRUP should be used with caution during pregnancy and in women planning for pregnancy. It is not recommended for use in breastfeeding women. It is also not recommended for use in new-borns, infants, and children (aged below 12 years) and is advised to be used with caution in elderly patients (aged 65 years and above) after consulting the doctor.  

The most common side effects of taking GRILINCTUS SYRUP are nausea, stomach discomfort, drowsiness, dizziness, extreme happiness, feeling drunk/high, and/or vomiting. Consult your doctor if any of these symptoms worsen.

Uses Of GRILINCTUS SYRUP

• Provides relief from cough and upper respiratory tract symptoms (including nasal congestion) associated with allergy/common cold in affected individuals

How GRILINCTUS SYRUP Works

GRILINCTUS SYRUP helps to provide relief from cough and upper respiratory tract symptoms (associated with allergy/common cold), where chlorpheniramine maleate works by managing the occurrence of allergic symptoms by blocking the action of histamine (substance responsible for allergic symptoms), dextromethorphan hydrobromide inhibits cough reflex by reducing the activity of certain receptors (responsible for cough reflex), and guaifenesin and ammonium chloride works by reducing the stickiness of the mucus resulting in its loosening & removal from the airways thus providing relief from cough and upper respiratory tract symptoms in affected individuals.

How to use GRILINCTUS SYRUP

Take GRILINCTUS SYRUP as advised by your physician. It is for oral use only. Shake well before use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Side Effects Of GRILINCTUS SYRUP

How To Manage Side Effects

Nausea and vomiting

Try to take GRILINCTUS SYRUP with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom gets worse.

Dizziness

Lie down until the dizziness passes and get up slowly. Do not bend down suddenly. Get a lot of rest. Walk slowly and carefully. Take plenty of fluids. Avoid drinking coffee, alcohol, or smoking. Consult your doctor if the condition persists for long or gets worsened.

Warning & Precautions

Pregnancy

GRILINCTUS SYRUP should be used with caution in pregnant women. Consult your doctor before taking the medicine.

Breastfeeding

GRILINCTUS SYRUP is not recommended for used in breastfeeding women. Consult your doctor before taking the medicine.

Kidney

GRILINCTUS SYRUP should be used with caution in patients with kidney problems such as acute renal failure. Consult your doctor before taking the medicine.

Liver

GRILINCTUS SYRUP should be used with caution in patients with liver diseases. Consult your doctor before taking the medicine.

Allergy

GRILINCTUS SYRUP is not recommended for use if you are allergic to chlorpheniramine maleate, dextromethorphan hydrobromide, guaiphenesin, ammonium Chloride, or any other ingredients of this medicine. Consult your doctor before taking the medicine.

Lungs

GRILINCTUS SYRUP is not recommended for use in patients with lung problems such as chronic bronchitis, lower respiratory tract conditions such as asthma. Consult your doctor before taking the medicine.

Heart Disease

GRILINCTUS SYRUP is not recommended for use in patients with heart diseases such as ventricular tachycardia (pounding heart rate) or severe coronary disease (disease of vessels supplying blood to heart muscles). Consult your doctor before taking the medicine.

Interactions

A. Drug-Drug Interactions

Before taking GRILINCTUS SYRUP, inform your doctor, if you are taking any of the following medicine:

• paracetamol (medicine used to manage fever and pain)

Overdosage:

If you or anyone else accidentally takes too much of GRILINCTUS SYRUP, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are vomiting and nausea.

Synopsis

More Information

• Keep the medicine out of reach in children
• Store GRILINCTUS SYRUP at room temperature

FAQs About GRILINCTUS SYRUP

What GRILINCTUS SYRUP is used for?

GRILINCTUS SYRUP is used to provide relief from cough and symptoms of upper respiratory tract which includes nasal congestion associated with allergy/common cold in affected individuals.

What happens if you take more GRILINCTUS SYRUP than your required dose?

If you or anyone else accidentally takes too much of GRILINCTUS SYRUP, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are vomiting and nausea.

What side effects are seen with the use of GRILINCTUS SYRUP?

The most common side effects associated with the use of GRILINCTUS SYRUP are nausea, stomach discomfort, drowsiness, dizziness, extreme happiness, feeling drunk/high, and/or vomiting. Consult your doctor if any of these symptoms worsen.

Who should avoid taking GRILINCTUS SYRUP?

GRILINCTUS SYRUP is not recommended for use if you are allergic to chlorpheniramine maleate, dextromethorphan hydrobromide, guaiphenesin, and/or ammonium chloride. It is also not recommended for use in patients suffering from heart diseases (such as ventricular tachycardia, severe coronary disease), lung diseases (such as chronic bronchitis, asthma), and/or severe rise in blood pressure. The medicine is also not indicated for use in breastfeeding women, new-borns, and infants. Consult your doctor before taking the medicine.

How GRILINCTUS SYRUP works?

GRILINCTUS SYRUP helps to provide relief from cough and upper respiratory tract symptoms (associated with allergy/common cold), where chlorpheniramine maleate works by managing the occurrence of allergic symptoms by blocking the action of histamine (substance responsible for allergic symptoms), dextromethorphan hydrobromide inhibits cough reflex by reducing the activity of certain receptors (responsible for cough reflex), and guaifenesin and ammonium chloride works by reducing the stickiness of the mucus resulting in its loosening & removal from the airways thus providing relief from cough and upper respiratory tract symptoms in affected individuals.

What is method of taking GRILINCTUS SYRUP?

Take GRILINCTUS SYRUP as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

What if I forget to take GRILINCTUS SYRUP dose?

If you forgot to take GRILINCTUS SYRUP dose, take it as early as possible. Do not double the dose to make up for the missed dose. Consult your doctor before taking the medicine.

Can GRILINCTUS SYRUP be used in pregnant and breastfeeding women?

Yes, GRILINCTUS SYRUP can be used but with caution in pregnant women. It is not recommended for use in breastfeeding women. Consult your doctor before taking the medicine.

Can GRILINCTUS SYRUP be used in children?

GRILINCTUS SYRUP is not recommended to be used in new-borns, infants, and children (below 12 years). It should be used with caution in children and adolescents (aged above 12 years). Consult your doctor before taking the medicine.

References

1. KD. Tripathi. Drugs For Cough and Bronchial Asthma. Essentials of medical pharmacology. Seventh edition. 2013. Page – 221

2. SaeRam Oh, Suneil Agrawal, Sarah Sabir, Alan Taylor. Dextromethorphan. NIH National Library of Medicine. National Centre for Biotechnology Information. StatPearls [Internet]. May 2022. [Accessed on 15th September 2022] https://www.ncbi.nlm.nih.gov/books/NBK538216/

3. D Larrey, G Babany, M Tinel, E Freneaux, G Amouyal, F Habersetzer, P Letteron, D Pessayre. Effect of liver disease on dextromethorphan oxidation capacity and phenotype: a study in 107 patients. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. September 1989. [Accessed on 15th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1379948/

4. Evan Small, Benjamin J Sandefur. Acute renal failure after ingestion of guaifenesin and dextromethorphan. NIH National Library of Medicine. National Centre for Biotechnology Information. PubMed.gov. March 2014. [Accessed on 15th September 2022] https://pubmed.ncbi.nlm.nih.gov/24630853/

5. H.G. Zaveri, S.M. Mansuri, V.J. Patel. Use of potentially inappropriate medicines in elderly: A prospective study in medicine out-patient department of a tertiary care teaching hospital. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. April 2010. [Assessed 15th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907023/

6. Reckitt Benckiser Healthcare UK Limited. Electronic Medicines Compendium (EMC). [Revised in March 2012] [Accessed on 15th September 2022] https://www.medicines.org.uk/emc/files/pil.616.pdf

7. Torque Pharmaceuticals Pvt. Ltd. COFMAC SYRUP. [Accessed on 15th September 2022] https://www.torquepharma.com/cofmac-syrup/

Useful Diagnostic Tests

• Blood tests
• Lung x-ray
• Lung CT scan

Author Details

Written By Dr. K .AZEEM HUSSAIN - B.D.S

Reviewed For Accuracy By Dr. Rajnikant - MBBS, MD (Physiology)

Last updated on 23 Jan 2023 | 07:35 PM(IST)