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Introduction About GRILINCTUS BM TABLET
GRILINCTUS BM TABLET is a combination of Bromhexine and Terbutaline which belongs to the group of medicines called Mucolytics and Bronchodilators respectively. GRILINCTUS BM TABLET is indicated for the symptomatic management of cough in acute and chronic bronchitis and other bronchospastic disorders such as eosinophilia and in smokers’s cough. In these conditions, the airways become inflamed and swollen causing difficulty in breathing. When the medicine is given in combination, it makes breathing easier and relives the discomfort.
Before taking GRILINCTUS BM TABLET, inform your doctor if you had or have stomach ulcer, diabetes, overactive thyroid gland, disease of the heart, low levels of potassium in the blood (hypokalaemia), intolerance to fructose (sugar), fits, or if you are taking any other medicines like antibiotics. Consult your doctor for advice before taking.
GRILINCTUS BM TABLET should be used with caution in pregnant women, breastfeeding women, and in elderly patients. GRILINCTUS BM TABLET is recommended in children above 2 years of age. The common side effects of GRILINCTUS BM TABLET are headache, nausea or vomiting, pain in the upper part of your abdomen, diarrhoea, palpitations. Consult your doctor immediately if any of the above side effects worsen or persists for a longer duration.
Uses Of GRILINCTUS BM TABLET
It is used to manage:
- cough in acute and chronic bronchitis
- bronchospastic disorders such as eosinophilia
- smokers’s cough
How GRILINCTUS BM TABLET Works
GRILINCTUS BM TABLET is a combination of Bromhexine and Terbutaline. Bromhexine is a mucolytics (agents that break down mucus present making it loose and thin) that it easier to cough out. Terbutaline is a bronchodilator which relaxes muscles in the airways, widens the airways and eases the symptoms.
How to use GRILINCTUS BM TABLET
Take GRILINCTUS BM TABLET as advised by your physician. Swallow GRILINCTUS BM TABLET with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of GRILINCTUS BM TABLET
Common
- trembling or shaking
- headache
- pounding or rapid heartbeats (palpitations)
- cramps or feeling tense
- muscle weakness, thirst, pins and needles (low levels of potassium)
Uncommon
- nausea, vomiting
- pain in the upper part of abdomen
- diarrhoea
Rare
- hypersensitivity reactions
- rash, urticaria (itching)
Stop taking GRILINCTUS BM TABLET and contact your doctor immediately if you are experiencing the following:
- serious allergic reactions that may cause swelling of face or throat, wheezing or sudden difficulties in breathing
- skin lesions such as severe blistering or peeling of your skin, mouth, throat, nose, eyes and genitals
- nervousness
- dizziness, drowsiness
- rapid heart rate
- shortness of breath
- chest discomfort
- flushed feeling and sweating
- anxiety
- dry mouth
How To Manage Side Effects
Diarrhea
Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.
Headache
Try to rest and relax. Apply pain balm on your forehead to ease off the pain. If there is no improvement in the symptom, contact your doctor.
Nausea And Vomiting
Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom gets worse.
Stomach Pain
Try to rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. If the symptom does not improve, contact your doctor.
Warning & Precautions
Pregnancy
Monitoring requiredGRILINCTUS BM TABLET is not recommended during pregnancy unless it is deemed necessary. Consult your doctor for advice.
Breastfeeding
Monitoring requiredGRILINCTUS BM TABLET is not recommended during breast feeding unless it is deemed necessary. Consult your doctor for advice.
Driving and Using Machines
Use with CautionGRILINCTUS BM TABLET does not influence the capacity of driving or operating any machines. Consult your doctor for advice.
Allergy
ContraindicatedDo not take GRILINCTUS BM TABLET if you are allergic to Bromhexine or Terbutaline or any other ingredients of this medicine.
Heart Disease
Use with CautionGRILINCTUS BM TABLET should be used with caution in patients with heart diseases. Consult your doctor for advice.
Use In Pediatrics
ContraindicatedGRILINCTUS BM TABLET is not recommended in children below 2 years of age. Consult your doctor for advice.
Use In Geriatrics
Use with CautionGRILINCTUS BM TABLET should be used with caution in elderly patients. Consult your doctor for advice.
Others
Before taking GRILINCTUS BM TABLET inform your doctor if you:
- have diabetes
- an overactive thyroid gland
- low levels of potassium in the blood (hypokalaemia)
- have intolerance to fructose
- are suffering from fits or have a history of fits
- are suffering from peptic ulcers
Interactions
A. Drug-Drug interactions:
Before taking GRILINCTUS BM TABLET, inform your doctor if you are taking any of the following medicine:
- antibiotics used to manage infections (Ex. ampicillin, amoxicillin)
- steroid medicines (Ex. prednisolone)
- xanthine to manage asthma (Ex. theophylline)
- beta-blockers used to manage blood pressure (Ex. atenolol, propranolol)
- eye medicine (Ex. timolol)
- medicines for urinary retention (Ex. furosemide)
Overdosage:
If you or anyone else accidentally takes too much of GRILINCTUS BM TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are abdominal pain, agitation, palpitations (being of your heartbeat), seizures/fits, hypertension, hypotension (fainting) tachycardia (increased heartbeat) nervousness, headache, tremor, dry mouth, nausea, dizziness, fatigue, malaise (weakness) and insomnia (sleeplessness).
Synopsis
| Drug | : | Bromhexine, Terbutaline |
| Pharmacological Category | : | Mucolytic, Beta-adrenergic agonist bronchodilator |
| Therapeutic Indication | : | Manages cough |
| Dosage Forms | : | Syrup, Tablet |
More Information
- Keep GRILINCTUS BM TABLET out of reach of children
- Store at room temperature
FAQs About GRILINCTUS BM TABLET
Q: What is GRILINCTUS BM TABLET used for?
A: GRILINCTUS BM TABLET is used to relieve cough associated with bronchitis, bronchial asthma, emphysema, and other broncho-pulmonary disorders.
Q: How is GRILINCTUS BM TABLET useful in managing severe cough?
A: GRILINCTUS BM TABLET is a combination of Bromhexine and Terbutaline medicine. Bromhexine is a mucolytic which thins and loosens mucus (phlegm), making it easier to cough out. Terbutaline is a bronchodilator which relaxes muscles in the airways, widens the airways and eases the symptoms. This collective action is useful in relief of cough and discomfort.
Q: How to use GRILINCTUS BM TABLET?
A: Take GRILINCTUS BM TABLET as advised by your physician. Swallow GRILINCTUS BM TABLET with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Q: What are the serious side effects are seen with GRILINCTUS BM TABLET?
A: Serious allergic reactions that may cause swelling of face or throat, wheezing or sudden difficulties in breathing, skin lesions such as severe blistering or peeling of your skin, mouth, throat, nose, eyes and genitals, uncontrollable shaking, nervousness, dizziness, drowsiness, difficulty falling asleep or staying asleep, weakness and sweating. Consult your doctor for advice, immediately.
Q: Will GRILINCTUS BM TABLET be more effective if taken in more than recommended doses?
A: No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms, that are not relieved by the recommended doses, consult your doctor for re-evaluation.
Q: Can GRILINCTUS BM TABLET use for pregnant women?
A: GRILINCTUS BM TABLET is generally not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before taking it.
References
1. KD. Tripathi. Drugs for Cough and Bronchial Asthma. Chapter 16 Essentials of medical pharmacology. Seventh edition. 2017.
2. Zanasi, A., Mazzolini, M. & Kantar, A. A reappraisal of the mucoactive activity and clinical efficacy of bromhexine.Springer.com Bromhexine and Terbutaline March 2017. [Accessed on 25th June 2022] https://link.springer.com/article/10.1186/s40248-017-0088-1#Sec11
3. Ireland Opella Healthcare. Bromhexine and Terbutaline. [Revised in September 2021 [Accessed on 25th June 2022] https://www.hpra.ie/img/uploaded/swedocuments/4550f813-c219-4e0a-b51a-5e6ed8a8e9f0.pdf
4. Laboratoire Unither. Bromhexine and Terbutaline. [ Revised in September 2021] [Accessed on 25th June 2022] https://www.medicines.org.uk/emc/files/pil.3216.pdf
5. Rxlist. Bromhexine and Terbutaline [Revised on March 2021] [Accessed on 25th June 2022] https://www.rxlist.com/terbutaline-sulfate-drug.htm
6. The National Center for Biotechnology Information advances science and health by providing access to biomedical and genomic information. [Revised on March 2005] [Accessed on 25th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/terbutaline#section=MeSH-Pharmacological-Classification
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