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Introduction About GOLDISTAT EZ 10/10MG TABLET
GOLDISTAT EZ 10/10MG TABLET is a combination of Atorvastatin and Ezetimibe which belongs to the group of medicines called Anti-hyperlipidemic agents. It is used for the management of patients with primary hypercholesterolemia (high amounts of cholesterol in the blood). It is used along with a proper diet to lower bad cholesterol and fats (LDL, triglycerides) and raise good cholesterol (HDL) in the blood.
High cholesterol is when you have too much of a fatty substance called cholesterol in your blood. Cholesterol is a type of fat (or lipid) in the blood. Having high levels of fats in the blood can lead to serious health problems such as heart disease.
Regular monitoring of blood sugar levels, and liver function is recommended while taking this GOLDISTAT EZ 10/10MG TABLET.
Before taking GOLDISTAT EZ 10/10MG TABLET, inform your doctor if you have any kidney or liver problems or heart problems or high blood pressure.
Pregnant and breastfeeding women should consult their doctor before taking this medicine.
The most common side effects of taking GOLDISTAT EZ 10/10MG TABLET are joint pain, diarrhoea, tendon problems, memory loss, confusion, depression, muscle and body pain. Contact your doctor if any of the above symptoms worsen.
Uses Of GOLDISTAT EZ 10/10MG TABLET
- Used along with a proper diet to help lower bad cholesterol and fats (such as LDL, triglycerides) and raise good cholesterol (HDL) in the blood
How GOLDISTAT EZ 10/10MG TABLET Works
GOLDISTAT EZ 10/10MG TABLET is a combination of Atorvastatin and Ezetimibe where Atorvastatin works by managing your body from making bad cholesterol (LDL) while raising good cholesterol (HDL) levels. Ezetimibe works by managing absorption of cholesterol from the intestines. Together, they provide better reduction of cholesterol in your body.
How to use GOLDISTAT EZ 10/10MG TABLET
Take GOLDISTAT EZ 10/10MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of GOLDISTAT EZ 10/10MG TABLET
Common
- muscle and body pain
- diarrhoea
- joint pain
- tendon problems
- memory loss
- confusion
- depression
Rare
Stop taking GOLDISTAT EZ 10/10MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- serious allergic reactions symptoms such as swelling of the face, lips, tongue, and/or throat that may cause difficultyin breathing or swallowing,rash, itching,severe dizziness, trouble breathing
- muscle problems such as rhabdomyolysis and autoimmune myopathy (symptoms such as unexplained muscle pain, tenderness, or weakness, especially fever or feel more tired than usual
- liver problems symptoms such as feel tired or weak, loss of appetite, upper belly pain, dark urine, yellowing of your skin or the whites of your eyes, severe stomach pain, persistent nausea, or vomiting.
- kidney problems symptoms such as change in the amount of urine
How To Manage Side Effects
Diarrhoea:
Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for managing diarrhoea. Consult your doctor if the symptom did not improve.
Warning & Precautions

Pregnancy
GOLDISTAT EZ 10/10MG TABLET is not recommended for use in pregnant women. Consult your doctor before taking this medicine.

Breastfeeding
GOLDISTAT EZ 10/10MG TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking this medicine.

Driving and Using Machines
Do not drive or operate any machines if you feel dizziness after taking GOLDISTAT EZ 10/10MG TABLET.

Alcohol
Consumption of alcohol is not recommended during management with this GOLDISTAT EZ 10/10MG TABLET because it can increase the risk of liver problems.

Kidney
GOLDISTAT EZ 10/10MG TABLET should be used with caution in patients with kidney problems. Consult your doctor before taking this medicine.

Liver
GOLDISTAT EZ 10/10MG TABLET is not recommended for use in patients with active liver disease.Consult your doctor before taking this medicine.

Allergy
Do not take GOLDISTAT EZ 10/10MG TABLET if you are allergic to Atorvastatin, Ezetimibe or any other ingredients of this medicine.
Others
Before taking GOLDISTAT EZ 10/10MG TABLET, inform your doctor if you have:
- thyroid problems
- diabetes
- unexplained muscle aches or weakness
- any other medical conditions
Use in pediatrics:
GOLDISTAT EZ 10/10MG TABLET is not recommended for use in children less than 6 years of age, because there is no information in this age group. Consult your doctor before taking this medicine.
Use in geriatrics:
GOLDISTAT EZ 10/10MG TABLET should be used with caution in elderly patients (above 65 years of age). Consult your doctor before taking this medicine.
Interactions
A. Drug-Drug interactions:
Before taking GOLDISTAT EZ 10/10MG TABLET, inform your doctor if you are taking any of the following medicine:
- cholestyramine, colestipol, gemfibrozil (used to manage cholesterol)
- daptomycin,telithromycin (used to manage infections)
- medicines used for birth control
- medicines used to manage heart failure
- ritonavir (used to manage HIV or AIDS)
- glecaprevir, pibrentasvir, telaprevir (used to manage hepatitis C)
- medicines used to manage gout
- cyclosporine (used to manage organ rejection)
B. Drug - Food interaction:
Avoid grapefruit or grapefruit juice or red yeast rice while taking GOLDISTAT EZ 10/10MG TABLET as it may increase the risk of side effects.
Overdosage:
If you or anyone else accidentally takes too much of GOLDISTAT EZ 10/10MG TABLET, consult your doctor immediately.
Synopsis
Drug | : | Atorvastatin, Ezetimibe |
Pharmacological Category | : | HMG-CoA reductase inhibitors, Cholesterol-lowering medications |
Therapeutic Indication | : | Manages hypercholesterolemia |
Dosage Forms | : | Tablet, Capsule |
More Information
- Keep GOLDISTAT EZ 10/10MG TABLET out of reach of children
- Store at room temperature
FAQs About GOLDISTAT EZ 10/10MG TABLET
Can I consume alcohol while taking [GBBNKEYWORD]?
No, avoid consumption of alcohol while taking this medicine. Follow the lifestyle modification suggested by your doctor such as quitting smoking or alcohol consumption during this therapy to achieve better results.
Will taking [GBBNKEYWORD] increase the risk of diabetes?
[GBBNKEYWORD] may raise your blood sugar a little. If you already have type 2 diabetes, consult your doctor. Your doctor may adjust the dosage of this medicine.
Is GOLDISTAT EZ 10/10MG TABLET effective?
Yes, it is effective if used in the dose and duration directed by your physician. Consult your doctor for advice.
Is there any lifestyle help for reducing bad cholesterol in our blood?
Increase your daily diet with fibre, fruits, vegetables, whole grains, fish, and cut saturated fat as well. Stop smoking and drinking and try to work out every day as well.
Can I take GOLDISTAT EZ 10/10MG TABLET during liver disease?
No, it is not recommended for use in patients with active liver disease. Consult your doctor before taking this medicine.
Can GOLDISTAT EZ 10/10MG TABLET cause diarrhoea?
Yes, this GOLDISTAT EZ 10/10MG TABLET may cause diarrhoea in some individuals. Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for managing diarrhoea. Consult your doctor if the symptom did not improve.
References
1. KD. Tripathi. Hypolipidaemic Drugs andPlasma Expanders. Essentials of medical pharmacology. Seventh edition. 2013. Page – 637& 641.
2. A Study to Evaluate the Effectiveness of Ezetimibe/Atorvastatin 10 mg/40 mg Combination Tablet Compared to Marketed Ezetimibe 10 mg and Atorvastatin 40 mg Tablets in Participants with High Cholesterol (MK-0653C-190 AM1). NIH: U.S. National Library of Medicine.ClinicalTrials.gov.9 Feb 2022 [Accessed on 11 Apr 2022] https://clinicaltrials.gov/ct2/show/NCT01370603
3. Christie M Ballantyne, John Houri, Alberto Notarbartolo, Lorenzo Melani, Leslie J Lipka, Ramachandran Suresh, Steven Sun, Alexandre P LeBeaut, Philip T Sager, Enrico P Veltri, Ezetimibe Study Group.Effect of ezetimibe coadministered with atorvastatin in 628 patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial.NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov. 20 May 2003.[Accessed on 11 Apr 2022] https://pubmed.ncbi.nlm.nih.gov/12719279/
4. Webmd.com.atorvastatin-ezetimibe tablet [Accessed on 11 Apr 2022] https://www.webmd.com/drugs/2/drug-164168/ezetimibe-atorvastatin-oral/details
5. Merck & Co., Inc, 2013; U.S. Food & Drug Administration; [Revised on May 2014] [Accessed on 11 Apr 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/200153s003lbl.pdf
Useful Diagnostic Tests
- Cholesterol - HDL
- Cholesterol - LDL
- Cholesterol – Total