Glycomet Trio Forte 2mg Tablet 10'S

Introduction About GLYCOMET TRIO FORTE 2 TABLET

Glycomet Trio Forte 2 Tablet is a carefully formulated combination medicine that supports maintaining balanced blood glucose levels (type 2 diabetes mellitus). It contains a blend of active ingredients Glimepiride, Metformin and Voglibose, designed for enhanced metabolic processing to help individuals seeking comprehensive sugar level regulation.

Take GLYCOMET TRIO FORTE 2 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

GLYCOMET TRIO FORTE 2 TABLET is not recommended for use in patients with acute conditions (such as dehydration or severe infection), severe ketosis (a severe complication of diabetes), severe trauma, lung problems, heart problems, and/or severe kidney or liver problems. Before taking GLYCOMET TRIO FORTE 2 TABLET, inform your doctor if you recently had trauma and/or have febrile infections, fever, uncontrolled diabetes, hypothyroidism (underactive thyroid), chronic intestinal disease, fever, or other kidney or liver problems.

GLYCOMET TRIO FORTE 2 TABLET is not recommended for use in pregnant and breastfeeding women since it may cause harm to the developing fetus or nursing child. It is also not recommended for use in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 75 years or older) after consulting the doctor.

Common side effects are nausea and vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and/or hypoglycemia (low blood sugar).

Key Composition

• Glimepiride 2 mg: Stimulates insulin release from pancreatic beta cells to aid glucose uptake.
• Metformin Hydrochloride 1000 mg SR: Reduces hepatic glucose production and enhances insulin sensitivity while slowing intestinal absorption.
• Voglibose 0.2 mg: Delays carbohydrate digestion by inhibiting alpha-glucosidase enzymes, limiting post-meal glucose spikes

Uses Of GLYCOMET TRIO FORTE 2 TABLET

• Manages Type II diabetes mellitus

Benefits of GLYCOMET TRIO FORTE 2 TABLET

• Supports Steady Blood Glucose Levels: Combination formula helps maintain balanced sugar throughout the day for consistent metabolic function.
• Controls Post-Meal Glucose Spikes: Voglibose delays carbohydrate absorption, smoothing out after-meal sugar rises.
• Enhances Insulin Sensitivity: Metformin improves how body responds to insulin while reducing liver glucose output.
• Stimulates Natural Insulin Release: Glimepiride prompts pancreatic beta cells for better glucose utilization.
• Promotes Metabolic Balance: Triple action supports comprehensive daily energy stability and carbohydrate processing.

How GLYCOMET TRIO FORTE 2 TABLET Works

GLYCOMET TRIO FORTE 2 TABLET contains a combination of three medicines namely, glimepiride, metformin, and voglibose. Each of these drugs works in a different way to help lower blood sugar:

1. Glimepiride: It stimulates the pancreas to release more insulin, which helps lower blood sugar by allowing cells to take in glucose.
2. Metformin: It decreases the amount of glucose produced by the liver and improves the sensitivity of muscle cells to insulin, allowing them to use glucose more effectively.
3. Voglibose: It inhibits enzymes in the gut that break down carbohydrates into glucose, slowing down the absorption of sugar from food.

Together, these actions help control blood sugar levels throughout the day by improving insulin secretion, reducing glucose production, and slowing sugar absorption.

How to use GLYCOMET TRIO FORTE 2 TABLET

Dosage Guidelines with Meals

Glycomet Trio Forte 2 Tablet is typically taken once daily with or immediately before meals, preferably breakfast or dinner, to enhance absorption and reduce stomach discomfort. This timing aligns with natural glucose fluctuations for optimal metabolic support.

How to Swallow the Tablet

Swallow the tablet whole with a full glass of water without crushing, chewing, or breaking to maintain sustained-release properties. This method ensures proper delivery of glimepiride, metformin, and voglibose throughout the day.

Daily Timing for Best Results

Take at the same fixed time each day, such as with breakfast or dinner, to establish consistent blood glucose patterns and maximize effectiveness. Regular timing supports steady metabolic balance without skipping doses.

Adjusting under Doctor Guidance

Dosage adjustments depend on blood sugar monitoring and health status, determined solely by healthcare professionals. Never alter independently to avoid risks like low glucose.

Meal Pairing Instructions

Pair with balanced meals containing fiber-rich foods like whole grains or vegetables to minimize digestive issues and support carbohydrate processing. Avoid empty stomach intake; always consume with food for best tolerance.

Overdose

If you or anyone else accidentally takes too much of GLYCOMET TRIO FORTE 2 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms include  hypoglycemia (low blood sugar), lactic acidosis, pancreatitis (inflammation of the pancreas), abdominal discomfort, and/or diarrhea.

Side Effects Of GLYCOMET TRIO FORTE 2 TABLET

Common Side Effects of GLYCOMET TRIO FORTE 2 TABLET:

• Nausea, vomiting, diarrhea, abdominal pain, and loss of appetite
• Metallic taste
• Hypoglycaemia (low blood sugar)

When to Report Symptoms?

• Severe hypoglycemia (very low blood sugar level)
• Signs of lactic acidosis (lactic acid built up in the bloodstream) such as exhaustion or extreme fatigue, body weakness, diarrhea, and/or headache

Warning & Precautions

Pregnancy

Contraindicated

GLYCOMET TRIO FORTE 2 TABLET is not recommended for use during pregnancy since it may cause harm to the fetus. Consult your doctor before taking it.

Breastfeeding

Contraindicated

GLYCOMET TRIO FORTE 2 TABLET is not recommended for use in breastfeeding women since the medicine may pass through breast milk and may cause harm to the nursing child. Consult your doctor before taking it.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you experience impaired alertness or reactions (due to hypoglycemia) while taking GLYCOMET TRIO FORTE 2 TABLET.

Alcohol

Contraindicated

Do not consume alcohol while taking GLYCOMET TRIO FORTE 2 TABLET since it may reduce your blood sugar level. Consult your doctor before taking it.

Kidney

Consult your doctor

GLYCOMET TRIO FORTE 2 TABLET is not recommended in patients with severe renal failure. It should be used with caution in patients with other kidney diseases. Consult your doctor before taking it.

Liver

Consult your doctor

GLYCOMET TRIO FORTE 2 TABLET is not recommended for use in patients with severe liver disease. It should be used with caution in patients with other liver diseases. Consult your doctor before taking it.

Allergy

Contraindicated

Do not take GLYCOMET TRIO FORTE 2 TABLET if you are allergic to glimepiride, metformin, voglibose, other sulfonylureas/sulphonamides, and/or any other ingredients of this medicine.

Lungs

Contraindicated

GLYCOMET TRIO FORTE 2 TABLET is not recommended for use in patients with lung problems such as acute or chronic respiratory failure. Consult your doctor before taking it. 

Heart Disease

Contraindicated

GLYCOMET TRIO FORTE 2 TABLET) is not recommended in patients with heart problems such as acute or chronic cardiac failure or recent myocardial infarction. Consult your doctor before taking it.

Use In Pediatrics

Contraindicated

GLYCOMET TRIO FORTE 2 TABLET is not recommended for use in children and adolescents (aged below 18 years) since the safety and effectiveness of the medicine are not established.

Use In Geriatrics

Use with Caution

GLYCOMET TRIO FORTE 2 TABLET should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking it.

Other Warnings for GLYCOMET TRIO FORTE 2 TABLET

Before taking GLYCOMET TRIO FORTE 2 TABLET, inform your doctor if you:

• Recently had trauma
• Had or scheduled for any surgery
• Suffer from febrile infections, fever, and/or uncontrolled diabetes
• Are undernourished and/or have irregular mealtimes or skipped meals
• Suffer from an imbalance between physical exertion and carbohydrate intake
• Have hypothyroidism (underactive thyroid)
• Have a history of laparotomy (a surgical incision done into the abdominal cavity for diagnosing a condition) and/or ileus (interrupted movement of the intestines)
• Suffer from chronic intestinal disease (accompanied by disturbances in digestion and absorption)
• Suffer from fever

Who should not take GLYCOMET TRIO FORTE 2 TABLET

GLYCOMET TRIO FORTE 2 TABLET is not recommended for use if you:

• Suffer from any acute type of metabolic acidosis (the buildup of excess acid in the body), such as lactic acidosis, diabetic ketoacidosis, and/or diabetic precoma
• Suffer from acute conditions such as dehydration, severe infection, and shock
• Have severe ketosis (a severe complication of diabetes)
• Are in a state of diabetic coma
• Had severe infections before or after the operation
• Had severe trauma
• Have gastrointestinal obstruction

Safety Advice

• Monitor Blood Sugar Regularly: Check glucose levels frequently to recognize low sugar signs like sweating, dizziness, or hunger; keep quick glucose sources (juice, candy) handy.
• Avoid Alcohol Completely: Alcohol increases low blood sugar risk and may worsen side effects; abstain during use.
• Inform Doctor of Health History: Disclose kidney/liver issues, allergies, pregnancy, or breastfeeding before starting for personalized guidance.
• Do Not Drive if Dizzy: Avoid driving or operating machinery if experiencing dizziness, blurred vision, or low sugar symptoms.
• Take Only as Prescribed: Never adjust dose, skip, or stop without doctor consultation to maintain metabolic balance.
• Stay Hydrated and Use Sunscreen: Drink plenty of fluids; protect skin from sun as medication increases sensitivity.

Diet and Lifestyle Advice

Diet Tips for Glycomet Trio Forte 2 Users

• High-Fiber Foods: Include whole grains (oats, brown rice, quinoa), leafy greens (spinach, broccoli), legumes (lentils, chickpeas), and nuts/seeds to slow sugar absorption.
• Lean Proteins: Choose skinless chicken, fish (salmon, tuna), eggs, tofu, paneer, or Greek yogurt for stable blood sugar and satiety.
• Low-GI Fruits: Opt for apples, berries, guava, or pears instead of high-sugar options like mango or jackfruit.
• Meal Frequency: Eat every 3-4 hours with 45-60g carbs per main meal (complex sources) and 15-30g per snack; drink 8-10 glasses water daily.
• Avoid Sugary/Processed: Skip white bread, maida, poori, noodles, fried rice, soda, candy, desserts, fruit juices, and excess oil curries.

Lifestyle Recommendations

• Regular Exercise: Aim for 30 minutes brisk walking or HIIT 3x/week to improve insulin sensitivity and weight management.
• Meal Timing: Align with tablet intake (breakfast/dinner) for balanced glucose; never skip meals to prevent low sugar.
• Weight Control: Maintain BMI <23 through portion control and activity for metabolic support.

Drug - Drug interaction

• Other Diabetes Medications: Combining with insulin, sulfonylureas (gliclazide, glibenclamide), or DPP-4 inhibitors (sitagliptin) increases low blood sugar risk.
• NSAIDs and Painkillers: Ibuprofen, diclofenac, naproxen may enhance insulin effects and affect kidney function.
• Blood Pressure Drugs: Beta-blockers, ACE inhibitors, diuretics (hydrochlorothiazide, furosemide) can alter glucose control or cause dehydration.
• Alcohol: Increases hypoglycemia risk and potential lactic acidosis; avoid completely.
• Antibiotics and Others: Sulfonamides, chloramphenicol, salicylates (aspirin), probenecid may amplify effects or cause toxicity.
• Herbal Supplements: Certain types may influence blood sugar; consult healthcare provider before use.

Synopsis

More Information

Glimepiride vs Metformin Mechanism Comparison

FAQs About GLYCOMET TRIO FORTE 2 TABLET

Q: What is GLYCOMET TRIO FORTE 2 TABLET used for?

A: GLYCOMET TRIO FORTE 2 TABLET is used in adults to manage type 2 diabetes mellitus when diet, exercise, and single-agent or second-line therapy with two drugs are insufficient to adequately control blood sugar levels.

Q: How does GLYCOMET TRIO FORTE 2 TABLET work?

A: Glimepiride lowers blood glucose levels by increasing the amount of insulin released by the pancreas. Metformin works by decreasing glucose production in the liver and the amount of glucose absorbed by the stomach and intestine. Voglibose works by inhibiting the alpha-glucosidase enzyme, which breaks down complex carbohydrates into simple sugars. This leads to a reduction in blood glucose levels in individuals with type 2 diabetes mellitus.

Q: What are the side-effects of GLYCOMET TRIO FORTE 2 TABLET?

A: The most common side-effects of GLYCOMET TRIO FORTE 2 TABLET are nausea and vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and/or hypoglycemia (low blood sugar).

Q: How do I take GLYCOMET TRIO FORTE 2 TABLET?

A: Take GLYCOMET TRIO FORTE 2 TABLET as advised by your physician. It is preferably taken with meals to avoid stomach upset. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

Q: What happens if GLYCOMET TRIO FORTE 2 TABLET is taken at more than its required dosage?

A: If you or anyone else accidentally takes too much of GLYCOMET TRIO FORTE 2 TABLET , symptoms of hypoglycemia (low blood sugar), lactic acidosis, pancreatitis (inflammation of the pancreas), abdominal discomfort, and/or diarrhea may occur.

Q: Can GLYCOMET TRIO FORTE 2 TABLET be used in pregnancy?

A: No, GLYCOMET TRIO FORTE 2 TABLET is not recommended for use during pregnancy since it may cause harm to the fetus.

Q: Who should not take GLYCOMET TRIO FORTE 2 TABLET?

A: GLYCOMET TRIO FORTE 2 TABLET is also not recommended for use in patients with acute conditions (such as dehydration or severe infection), severe ketosis, severe trauma, lung problems, heart problems and/or severe kidney or liver problems.

Q: Can GLYCOMET TRIO FORTE 2 TABLET be used in children?

A: No, GLYCOMET TRIO FORTE 2 TABLET is not recommended for use in children and adolescents (aged below 18 years).

References

1. KD Tripathi. Insulin, Oral Hypoglycaemic Drugs and Glucagon. Essentials of Medical Pharmacology. Seventh Edition. 2019. Page – 270, 275, 277.

2. Kalra S, Das AK, Priya G, Ghosh S, Mehrotra RN, Das S, Shah P, Bajaj S, Deshmukh V, Sanyal D, Chandrasekaran S, Khandelwal D, Joshi A, Nair T, Eliana F, Permana H, Fariduddin MD, Shrestha PK, Shrestha D, Kahandawa S, Sumanathilaka M, Shaheed A, Rahim AA, Orabi A, Al-Ani A, Hussein W, Kumar D, Shaikh K. Fixed-dose combination in management of type 2 diabetes mellitus. NIH National Library of Medicine. National center for biotechnology information. PMC PubMed Central. [Revised in November 2020] [Accessed on 8th December 2025] 

3. Windlas Biotech Private Limited. Amaryl MV 1mg, Amaryl MV 2mg. [Revised in March 2021] [ [Accessed on 8th December 2025] 

4. Primus Remedies Pvt. Ltd. Voglow GM1 Fort. [Accessed on 8th December 2025] 

5. Eris Lifesciences. Glimisave MV 1.3 F, Glimisave MV 2 forte, Glimisave MV 3.3, Glimisave MV 3.3 F. [Accessed on 8th December 2025] 

6. Leeford Healthcare Ltd. VOGLIMET-GM FORTE. [Accessed on 8th December 2025] 

7. Ikon Remedies Pvt. Ltd. Voglicon-GM Tablets. [Accessed on 8th December 2025] 

Useful Diagnostic Tests

• HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
• Blood Glucose Fasting (FBS)
• Random Blood Sugar (RBS)
• Post Prandial Blood Sugar (PPBS)
• Insulin-Fasting
• Insulin Postprandial (PP)
• Vital Diabetes Care
• Extended Diabetes Care
• Advance Diabetes Care
• Comprehensive Diabetes Care

Author Details

Written By Srilekha. R - B.Pharm

Reviewed For Accuracy By Dr. Jaya Prabakaran - MBBS, MD (Diabetology and Family Medicine)

Last updated on 21 Nov 2024 | 03:18 PM(IST)