Glycomet 1gm Tablet 15'S

Introduction About GLYCOMET 1GM TABLET

Glycomet 1gm Tablet (Metformin) is an oral medication commonly prescribed to help manage type 2 diabetes. It plays a crucial role in controlling blood sugar levels by improving the body’s response to insulin. Metformin, the active ingredient, works by reducing the amount of glucose produced by the liver and improving how the body handles glucose in the bloodstream.    

It is ideal for patients who have difficulty controlling their blood sugar levels through diet and exercise alone. Research shows that Metformin not only helps in lowering blood glucose but also plays a role in improving insulin sensitivity. Patients with overweight or obesity can particularly benefit from this medication, as it may also support weight management as part of a holistic approach to diabetes care. It is often prescribed as a first-line therapy due to its effectiveness and relatively low risk of causing low blood sugar (hypoglycemia).   

Glycomet 1gm should be taken orally, usually with meals to reduce the likelihood of gastrointestinal upset. It's important to follow the dosage prescribed by your healthcare provider as it can vary depending on your specific needs and blood glucose levels. The medication should be taken consistently at the same time each day to help maintain steady blood sugar levels. It's crucial to stay hydrated and monitor kidney function regularly as Metformin is primarily excreted by the kidneys. 

While Glycomet 1gm is effective certain precautions should be observed. It is not suitable for individuals with kidney disease or severe liver impairment. Patients who have a history of lactic acidosis, a rare but serious complication should avoid Metformin. Common side effects may include gastrointestinal issues such as nausea, diarrhea and abdominal discomfort especially when starting the medication.  

Glycomet 1gm is not recommended during pregnancy unless explicitly prescribed by a healthcare provider. If you are pregnant or planning to become pregnant, discuss your treatment options with your doctor. It is also unknown whether Metformin passes into breast milk, so it's important to consult with your doctor before using this medication while breastfeeding. 

Uses Of GLYCOMET 1GM TABLET

• Effective for managing Type 2 diabetes
• Improves insulin sensitivity and aids in weight loss (off-label use)

Benefits of GLYCOMET 1GM TABLET

Glycomet 1gm tablet for diabetes

Glycomet 1gm Tablet, containing Metformin, is widely used to support blood sugar control in individuals with type 2 diabetes. It works by improving the body’s response to insulin and reducing the amount of sugar produced by the liver. Glycomet is often recommended as a first-choice oral medication due to its proven long-term safety and effectiveness. It is suitable for adults whose sugar levels are not well-managed by lifestyle changes alone.

Clinical studies like the UKPDS confirm that Metformin helps lower fasting glucose and HbA1c effectively. It also has a positive safety profile for long-term use, with minimal risk of weight gain

Weight loss benefits of Glycomet 1gm for insulin resistance and obesity

Glycomet 1gm may aid in modest weight loss especially in individuals with insulin resistance or obesity-related metabolic concerns. Research in Obesity Reviews shows weight reductions of 1.5–2.9 kg over several months of use. It may help reduce appetite and improve fat metabolism supporting better body weight control. This is especially useful for overweight adults or those with PCOS and type 2 diabetes.  

How GLYCOMET 1GM TABLET Works

How Glycomet helps control blood sugar

Glycomet 1gm helps manage high blood sugar by supporting how your body uses insulin more effectively. It does not increase insulin production but helps insulin already present in your body work better. This allows glucose (sugar) in the blood to enter the cells more efficiently, keeping blood sugar levels in a healthy range. It’s especially helpful for people with type 2 diabetes who have high sugar levels despite diet and activity efforts.

Glycomet effect on liver glucose production

One of the main actions of Glycomet is to reduce the amount of sugar your liver produces. In type 2 diabetes, the liver often releases too much glucose into the blood, especially between meals and overnight. Glycomet helps slow this process down, which leads to lower fasting blood sugar levels. This makes it effective for morning sugar spikes and overall blood sugar stability throughout the day. 

How Glycomet Helps Improve Insulin Sensitivity

Insulin sensitivity means how well your body responds to insulin. In many people with type 2 diabetes, the cells stop responding properly—a condition called insulin resistance. Glycomet works by improving the sensitivity of muscle, fat, and liver cells to insulin. When the body responds better to insulin, sugar can move from the blood into the cells more easily, helping to manage sugar levels naturally.

How Glycomet improves glucose uptake in muscles

Muscles play a key role in using up blood sugar for energy. Glycomet helps muscles absorb more glucose from the bloodstream, especially after meals. It does this by enhancing the pathways that allow sugar to enter muscle cells. This not only helps lower blood sugar but also improves energy use, which is important for people with insulin resistance or metabolic issues.

How Glycomet 1gm tablet contributes to weight reduction in type 2 diabetes

Glycomet may support modest weight loss in people with type 2 diabetes especially those who are overweight. It may reduce appetite slightly and improve how the body uses fat for energy. Unlike some diabetes medications that can cause weight gain, Glycomet is often considered weight-neutral or mildly weight-reducing. Combined with healthy eating and exercise, it can contribute to better weight management. 

How to use GLYCOMET 1GM TABLET

Recommended dosage of Glycomet 1gm

• Starting Dose: 500 mg once daily with the evening meal
• Adjustments: Your doctor may gradually increase the dose based on your blood sugar levels and how well you tolerate the medication
• Maximum Dose: 2000 mg per day divided into two or three doses
• Administration: Swallow the tablet whole with a glass of water. Do not chew, crush or break it

Glucomet 1gm tablet with or without food

• Recommendation: Take with food to reduce the risk of stomach upset
• Timing: Preferably with the evening meal, as per your doctor's instructions
• Note: Taking the tablet with food can also help improve its absorption

Best Time of Day to Take Glycomet 1gm Tablet

• Optimal Timing: Evening meal, unless otherwise directed by your healthcare provider
• Consistency: Take the tablet at the same time each day to maintain steady blood sugar levels
• Multiple Doses: If prescribed more than one dose per day, follow your doctor's instructions on timing.

What happens if you miss a dose of Glycomet 1gm?

• If Close to Next Dose: Skip the missed dose - do not take two doses at the same time
• If Far from Next Dose: Take the missed dose as soon as you remember unless it's almost time for your next scheduled dose
• Avoid Double Dosing: Do not double the dose to make up for a missed one

What if I forgot to take GLYCOMET 1GM TABLET

What happens if you miss a dose of Glycomet 1gm?

• If Close to Next Dose: Skip the missed dose - do not take two doses at the same time
• If Far from Next Dose: Take the missed dose as soon as you remember unless it's almost time for your next scheduled dose
• Avoid Double Dosing: Do not double the dose to make up for a missed one

Overdose

Overdose symptoms of Glycomet 1gm tablet

• Gastrointestinal Symptoms: Nausea, vomiting, diarrhea and abdominal discomfort.
• Metabolic Disturbances: Lactic acidosis, characterized by rapid breathing, muscle pain and fatigue.
• Neurological Effects: Dizziness, confusion and in severe cases, loss of consciousness.
• Cardiovascular Symptoms: Low blood pressure (hypotension), slow heart rate (bradycardia) and irregular heartbeat.
• Severe Cases: Potential for shock and organ failure if not treated promptly.?

How to Handle an Overdose of Glycomet 1gm Tablet

• Immediate Action: Contact emergency medical services or go to the nearest hospital immediately. 
• Do Not Wait: Even if symptoms are mild, seek medical attention as soon as possible.
• Provide Information: Inform healthcare providers about the amount of Glycomet taken, time of ingestion and any other medications consumed.
• Medical Intervention: Treatment may include intravenous fluids, medications to correct metabolic acidosis, and in severe cases, dialysis to remove metformin from the bloodstream.

Side Effects Of GLYCOMET 1GM TABLET

Common Side Effects of Glycomet 1gm Tablet:

• diarrhea
• stomach pain
• loss of appetite
• changes in taste, metallic taste

Glycomet 1gm Tablet Side Effects on Stomach:

Stomach-related side effects of Glycomet 1gm include nausea, diarrhea, bloating and abdominal discomfort. These are most often seen when starting the medication and can usually improve with time or by taking the tablet with meals. If symptoms persist, consult your healthcare provider.

Glycomet 1gm and Hypoglycemia:

Glycomet 1gm generally does not cause hypoglycemia (low blood sugar) on its own, as it works by improving insulin sensitivity rather than directly increasing insulin. However, if used alongside other diabetes medications that lower blood sugar (like insulin or sulfonylureas) there may be a risk of hypoglycemia. Always monitor your blood sugar and watch for signs of low blood sugar, such as shaking or dizziness.

Long-Term Side Effects of Glycomet 1gm Tablet:

Long-term use of Glycomet 1gm may lead to vitamin B12 deficiency, which can cause fatigue and numbness. There's also a rare risk of lactic acidosis, a serious condition where lactic acid builds up in the blood. Kidney function should be monitored regularly, as Metformin is processed by the kidneys. Regular check-ups with your healthcare provider are essential for safe long-term use.

When to Seek Medical Attention?

Stop taking GLYCOMET 1GM TABLET and consult your doctor immediately if you experience any of the following side effects:

• serious allergic reaction (such as hives, swelling of the face, lips, tongue or throat causing difficulty in breathing or swallowing)
• signs of liver problems (such as nausea or vomiting, stomach pain, unusual or unexplained tiredness, loss of appetite, dark urine, yellowing of the skin or the whites of the eyes)
• signs of lactic acidosis (cold hands or feet, dizziness or light-headedness, slow or irregular heartbeat, weakness or tiredness, unusual muscle pain, trouble breathing, sleepiness or drowsiness, stomach pains, nausea or vomiting)

How To Manage Side Effects

Nausea 

1. Take with Food: To help reduce nausea, take Glycomet 1gm with a meal. This can help buffer the stomach and make it easier to tolerate the medication.
2. Start with a Lower Dose: If you're just starting Glycomet, your doctor may recommend beginning with a lower dose and gradually increasing it. This approach allows your body to adjust to the medication and can help minimize nausea.
3. Stay Hydrated: Dehydration can worsen nausea, so it’s important to drink plenty of water throughout the day. Small, frequent sips of water can be easier to tolerate than drinking large amounts at once.
4. Avoid Strong Smells and Triggers: Certain smells or foods can trigger nausea. Avoid greasy, spicy, or strongly aromatic foods when you feel nauseous, as these may worsen symptoms.
5. Use Natural Remedies: Ginger and peppermint are well-known remedies for nausea. Sipping ginger tea or sucking on peppermint candies can sometimes help soothe your stomach and reduce feelings of nausea
6. Consult Your Doctor: If nausea persists, despite following these steps, or becomes severe, speak with your healthcare provider. They may suggest an anti-nausea medication or consider adjusting your dosage.

Stomach Upset

1. Take with Food: To ease stomach upset, always take Glycomet 1gm with a meal. This helps reduce irritation and discomfort in your stomach, preventing or lessening feelings of bloating, gas, or indigestion.
2. Start with a Low Dose: If you’re new to Glycomet, starting with a lower dose can help your digestive system adjust gradually, reducing the chances of stomach upset.
3. Avoid Heavy, Fatty, or Spicy Foods: While taking Glycomet, it’s a good idea to avoid foods that are rich in fat or spice, as these can irritate your stomach and make symptoms like bloating or cramping worse.
4. Take in Smaller Doses: If your prescribed dosage is high, consider dividing the dose into smaller amounts taken throughout the day. This helps prevent overwhelming your digestive system all at once.
5. Consider Antacids (if advised by your doctor): In some cases, a mild antacid may help reduce stomach discomfort. Always ask your doctor before taking any over-the-counter medication for stomach upset.
6. Give Your Body Time to Adjust: It’s common to experience stomach upset during the initial phase of taking Glycomet. The symptoms often subside after a few days as your body adjusts to the medication.
7. Consult Your Doctor: If stomach upset continues or becomes more intense, speak with your healthcare provider. They may recommend a different medication or make adjustments to your treatment plan.

Warning & Precautions

Pregnancy

Consult your doctor

There is a limited amount of data from the use of GLYCOMET 1GM TABLET in pregnant women. Hence consult your doctor for advice.

Breastfeeding

Consult your doctor

There is a limited amount of data from the use of GLYCOMET 1GM TABLET in breastfeeding women. Hence consult your doctor for advice.

Driving and Using Machines

Use with Caution

Do not drive or operate any heavy tools or machines if your ability is affected by the medicine.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking GLYCOMET 1GM TABLET as it may increase the risk of unwanted side effects.

Kidney

Contraindicated

GLYCOMET 1GM TABLET is not recommended for use in patients with severe kidney problems.

Liver

Consult your doctor

GLYCOMET 1GM TABLET is not recommended for use in patients with severe liver problems. It should be used with caution in patients with other liver problems.

Allergy

Contraindicated

Do not take GLYCOMET 1GM TABLET if you are allergic to Metformin or any other ingredients of this medicine.

Lungs

Contraindicated

It is not recommended for use in patients with severe infection of lungs or respiratory tract.

Heart Disease

Contraindicated

GLYCOMET 1GM TABLET is not recommended for use in patients with heart problems (such as acute heart failure or a recent heart attack).

Use In Pediatrics

Consult your doctor

GLYCOMET 1GM TABLET has not been studied in children. Consult your doctor for advice.

Use In Geriatrics

Use with Caution

GLYCOMET 1GM TABLET should be used with caution in elderly patients (aged above 65 years).

Safety Advice

Expert Advice on managing blood sugar levels when you take Glycomet

When you take Glycomet 1gm Tablet (Metformin), managing your blood sugar levels effectively requires combining medication with lifestyle changes.

• Follow your prescribed dose: Always take the medication as directed by your healthcare provider to maintain stable blood sugar levels.
• Balanced diet: Focus on a diet rich in vegetables, whole grains, lean proteins, and healthy fats. This helps stabilize blood sugar levels.
• Regular exercise: Physical activity enhances insulin sensitivity and helps control blood sugar. Aim for at least 30 minutes of moderate exercise most days of the week.
• Regular blood sugar monitoring: Keep track of your blood sugar to understand how your body responds to food, medication, and exercise.

Note: If you notice any significant changes in your blood sugar, talk to your doctor about adjusting your treatment plan.

Clinical Insights: How Glycomet Can Support Weight Loss During Fasting

Glycomet (Metformin) may contribute to modest weight loss, particularly in people with type 2 diabetes. When paired with intermittent fasting (a popular form of calorie restriction), Metformin can help enhance fat burning and support weight management.

• Improved Insulin Sensitivity: Metformin helps improve insulin sensitivity, which can make your body more efficient at using stored fat for energy during fasting periods.
• Reduced Appetite: Some studies suggest that Metformin might reduce appetite, which could naturally lead to fewer calories consumed during fasting and meals.
• Modest Weight Loss: Clinical studies have shown that Metformin can result in a modest weight loss of approximately 1.5–3 kg over the course of several months, especially when combined with diet and exercise.

Suggest appropriate timing for taking Glycomet in relation to fasting periods and meals.

For optimal results, the timing of Glycomet 1gm Tablet should align with your eating schedule and fasting periods:

• Take Glycomet with Meals: To avoid stomach upset, it’s best to take Glycomet with food. If you're following an intermittent fasting schedule, you would typically take your Glycomet 1gm Tablet during your eating window (e.g., at the beginning of your meal).
• Timing During Fasting: While Glycomet can be taken during fasting periods, it’s important to follow your healthcare provider’s advice regarding its use with fasting. Some individuals may prefer taking Glycomet just before or during the first meal of their eating window to prevent potential gastrointestinal discomfort.
• Split Doses: If your doctor has prescribed more than one dose, it’s often recommended to split the doses and take them with meals. For example, if you take Glycomet 1gm Tablet twice a day, one dose can be taken at the start of your lunch and the other with dinner.

Diet and Lifestyle Advice

Should I avoid any specific foods while on Glycomet 1gm?

While on Glycomet 1gm Tablet, there are no specific foods that you must strictly avoid. However, to ensure the best outcomes for managing your blood sugar, here are some general guidelines:

• Limit Sugary Foods: High-sugar foods like candies, sodas, and sugary desserts can cause blood sugar spikes, which Glycomet works to control. It's best to limit these foods to keep your blood sugar levels steady.
• Reduce Refined Carbs: Foods like white bread, pastries and certain processed snacks can cause rapid spikes in blood glucose. Opt for whole grains instead to help keep blood sugar under control.
• Watch for Gastrointestinal Discomfort: Glycomet can sometimes cause mild stomach upset. To minimize this avoid very spicy or fatty foods which may worsen gastrointestinal issues.
• Alcohol in Moderation: Excessive alcohol can interfere with how Glycomet works and may increase the risk of low blood sugar. It's safe to enjoy alcohol in moderation, but it’s important to discuss this with your doctor.

Best Diet Plan for People on Glycomet Tablets

For individuals taking Glycomet 1gm Tablet (Metformin) to manage type 2 diabetes, maintaining a well-balanced diet is key to controlling blood sugar levels. A proper diet plan can help manage insulin sensitivity and prevent complications

Breakfast Suggestions

• Whole Grains: Start the day with whole grains like oats, poha or whole wheat paratha. These are rich in fiber, which helps regulate blood sugar levels by slowing down the absorption of glucose into the bloodstream.
• Low Glycemic Index (GI) Fruits: Include fruits such as apple, pear and guava in your breakfast. These fruits have a low GI and are less likely to cause rapid spikes in blood sugar.
• Protein-Rich Foods: Opt for foods high in protein like Greek yogurt or eggs. Protein helps stabilize blood sugar levels and keeps you feeling full longer, reducing the temptation for unhealthy snacks later in the day.

Mid-Morning Snack Suggestions

• Nuts and Seeds: A small handful of almonds, walnuts, or flaxseeds is a great snack choice. These provide healthy fats, fiber, and protein, which support blood sugar regulation and keep hunger at bay.
• Vegetables: Eating raw vegetables like carrot sticks, cucumber, or tomato is a great way to add fiber and antioxidants to your diet without increasing blood sugar levels.
• Low-GI Fruits: Fresh fruits like papaya, berries, or pears are excellent for mid-morning snacks due to their fiber content and low glycemic index.

Lunch Suggesstions

• Whole Grains with Protein: Brown rice, millets or quinoa are excellent alternatives to refined rice and wheat. Pair these with lentils (dal) or chickpeas (chana) for a well-rounded meal that’s high in fiber and protein.
• Vegetable-based Dishes: A variety of vegetables like spinach, bottle gourd, cauliflower, and beans should be included. These provide essential vitamins and minerals, along with fiber to help control blood sugar levels.
• Lean Proteins: Include lean sources of protein such as tofu, paneer, chicken or fish. Protein helps regulate blood sugar and aids in muscle repair and growth.

Evening Snack Suggestions

• Sprouted Legumes: Sprouts like moong dal or chickpeas are a great option for an evening snack. They are rich in fiber and protein, which helps keep blood sugar levels stable.
• Low-Calorie Veggies: A small serving of vegetables like cucumber, tomato, or carrot sticks can curb your hunger without causing a spike in blood sugar.
• Buttermilk or Herbal Teas: Buttermilk or unsweetened herbal teas (like green tea) are light, hydrating, and can aid digestion. Avoid sugary beverages, which can quickly raise blood sugar.

Dinner Suggestions

• Light, Balanced Meals: Keep dinner light but nutritious. Include whole wheat roti or millets paired with dal, vegetable curry, or grilled chicken or fish for protein.
• Avoid Heavy Carbs: Minimize intake of white rice, fried foods, and refined carbs for dinner as these can lead to high blood sugar spikes at night.
• High-Fiber Vegetables: Vegetables like broccoli, zucchini, and pumpkin are great choices for dinner. These fiber-rich vegetables help control blood sugar and improve digestion.

Exercise Tips for Type 2 Diabetics Taking Glycomet

Exercise is an essential part of managing type 2 diabetes, and it can be especially helpful when combined with Glycomet 1gm Tablet. Here are some tips to ensure your workouts are safe and effective:

• Aim for Consistency: Try to be active for at least 30 minutes most days of the week. Consistency helps improve insulin sensitivity and better control blood sugar.
• Choose Low-Impact Activities: If you're new to exercise or have joint pain, try activities like walking, swimming, or cycling. These are gentle on the body but still provide excellent cardiovascular benefits.
• Incorporate Strength Training: Building muscle mass can improve insulin sensitivity. Aim for strength training exercises (such as using light weights, resistance bands, or body-weight exercises like squats) 2–3 times per week.
• Monitor Your Blood Sugar: Exercise can lower blood sugar levels, so it’s important to check your blood sugar before and after exercise. If your blood sugar is too low (below 70 mg/dL), eat a small snack before starting your workout.
• Stay Hydrated: Drink plenty of water before, during, and after exercise to stay hydrated. Glycomet can sometimes cause dehydration, and staying hydrated will help prevent this.
• Avoid Overexertion: Start slow, especially if you’re just beginning to exercise, and gradually increase the intensity over time. Overdoing it could lead to low blood sugar or injury

Glycomet vs. Glucophage: Which is Better?

Glycomet vs. Metformin: What’s the Difference?

Is Glycomet Better Than Gluconorm for Sugar Control?

Glycomet and Gluconorm are both used to manage blood sugar levels in individuals with type 2 diabetes, but they differ in their composition.

• Glycomet contains Metformin which works by improving insulin sensitivity, reducing liver glucose production and enhancing glucose uptake in muscles.
• Gluconorm contains both Metformin (like Glycomet) and glimepiride, an additional medication that helps stimulate insulin secretion and reduce blood sugar levels after meals.

Which is Better?

• If you have type 2 diabetes and Metformin alone is effective for managing your blood sugar, Glycomet might be enough.
• If your blood sugar is harder to control with Metformin alone, Gluconorm, with its added glimepiride, may offer more benefit in terms of blood sugar regulation.

Real Results from Glycomet Users

Many people with type 2 diabetes find Glycomet 1gm Tablet to be effective in managing their blood sugar levels. Some common results reported by users include:

• Blood Sugar Control: After a few weeks, users often notice a significant improvement in blood glucose levels, with reduced fasting blood sugar readings and more stable post-meal sugar levels.
• Weight Management: Some users report modest weight loss as Glycomet helps improve insulin sensitivity. This may be particularly helpful for those who are overweight or obese.
• Side Effects: While Glycomet is generally well tolerated, some users may experience stomach upset, such as nausea or diarrhea, especially when starting the medication. These side effects usually subside as the body adjusts.

Common Myths vs. Facts

Drug - Drug interaction

Glycomet 1gm Tablet, which contains Metformin, is commonly prescribed to manage type 2 diabetes. However, like all medications, it can interact with other drugs, potentially altering their effects or increasing the risk of side effects. It’s crucial to inform your doctor about all the medications, including over-the-counter drugs, supplements, and herbal products you are currently taking. Below are some key drug-drug interactions to be aware of while taking Glycomet:

Insulin and Other Oral Antidiabetic Medications

• Interaction: When taken together with insulin or other oral antidiabetic medications (such as sulfonylureas) the risk of low blood sugar (hypoglycemia) increases.
• Management: Your healthcare provider may need to adjust the doses of your other diabetes medications to avoid hypoglycemia.

Diuretics (Water Pills)

Examples: Furosemide, Hydrochlorothiazide

• Interaction: Diuretics can increase the risk of lactic acidosis (a rare but serious condition) when taken with Metformin. They may also cause dehydration, which can lead to kidney problems.
• Management: If you are prescribed a diuretic along with Glycomet, your doctor may monitor kidney function more closely and ensure proper hydration.

Corticosteroids

Examples: Prednisolone, Hydrocortisone

• Interaction: Corticosteroids can increase blood glucose levels by reducing the effectiveness of Glycomet.
• Management: Your healthcare provider may need to monitor your blood sugar levels more frequently and adjust your Glycomet dosage while you're on corticosteroids.

Beta-Blockers

Examples: Propranolol, Atenolol

• Interaction: Beta-blockers can mask the symptoms of hypoglycemia, making it harder to recognize low blood sugar levels when taking Glycomet.

• Management: Regular blood glucose monitoring is important. Your doctor may adjust your diabetes treatment plan to minimize the risk of undetected hypoglycemia.

ACE Inhibitors and ARBs

Examples: Lisinopril, Losartan

• Interaction: These drugs, often used to manage high blood pressure, can enhance the blood sugar-lowering effect of Glycomet, which might increase the risk of hypoglycemia.
• Management: While this combination can be beneficial for some, close monitoring of blood sugar levels is recommended, especially in the initial stages.

Contrast Agents (Used in X-rays or CT Scans)

Examples: Iodine-containing contrast agents

• Interaction: Contrast agents used in imaging procedures can cause kidney damage, which may increase the risk of lactic acidosis in individuals taking Metformin.
• Management: Discontinue Glycomet 48 hours before undergoing any imaging procedure that involves contrast agents, and resume only after kidney function is confirmed to be normal.

Certain Antibiotics

Examples: Ciprofloxacin, Rifampin

• Interaction: Some antibiotics can affect blood glucose levels, potentially increasing the risk of hypoglycemia or hyperglycemia when taken with Glycomet.
• Management: Close monitoring of blood glucose levels is necessary when taking antibiotics along with Glycomet.

Other Kidney-Effecting Medications

Examples: Non-steroidal anti-inflammatory drugs (NSAIDs), Aminoglycosides

• Interaction: These medications may impair kidney function, and since Metformin is excreted via the kidneys, impaired kidney function can lead to a build-up of the drug in the body, increasing the risk of lactic acidosis.
• Management: Your doctor may monitor kidney function more frequently and consider dosage adjustments. 

Drug - Food interaction

Metformin is generally well tolerated, food can affect how the drug works in the body. Understanding the food interactions with Glycomet is essential for optimizing its effectiveness and avoiding potential side effects.

Alcohol

• Interaction: Alcohol can significantly increase the risk of developing lactic acidosis, a rare but serious side effect of Metformin. It can also interfere with the liver’s ability to produce glucose, leading to low blood sugar (hypoglycemia), especially in individuals who are on medications for diabetes.
• Recommendation: It is advisable to limit or avoid alcohol while on Glycomet. If you choose to drink, it should be in moderation, and you should monitor your blood sugar levels closely.

Foods High in Sugar or Refined Carbohydrates

• Interaction: Foods such as white bread, sweets, sugary beverages, and processed snacks can cause blood sugar spikes. Glycomet works by improving the body’s response to insulin and helping manage blood sugar, but consuming too many high-sugar or high-carb foods can counteract its effectiveness.
• Recommendation: Follow a balanced diet with a focus on low glycemic index (GI) foods and complex carbohydrates. This helps in better blood sugar control and ensures Glycomet works optimally.

High-Fiber Foods

• Interaction: While fiber is an essential part of a diabetes-friendly diet, foods high in fiber (like whole grains, vegetables, and legumes) may affect the absorption of Metformin and slightly delay its action.
• Recommendation: Fiber-rich foods should be part of your diet, but you should monitor the timing of when you take Glycomet. It’s best to take the medication with meals to reduce stomach upset and ensure better absorption.

 Foods High in Vitamin B12

• Interaction: Long-term use of Metformin may reduce the absorption of Vitamin B12 from food, potentially leading to a deficiency over time.
• Recommendation: Include foods rich in Vitamin B12 such as dairy products, eggs, fish, and meat in your diet. If you are on Glycomet for a long period, your doctor may recommend Vitamin B12 supplements or periodic blood tests to check for deficiencies.

Caffeine

• Interaction: While there is no direct interaction between Metformin and caffeine, caffeine can affect blood sugar levels by increasing insulin resistance and triggering a temporary rise in blood glucose. This can make blood sugar management harder while on Glycomet.
• Recommendation: Limit the consumption of caffeinated beverages like coffee, tea, and energy drinks. If you do drink caffeine, ensure that you monitor your blood sugar levels more closely.

Large Amounts of High-fat Foods

• Interaction: Eating large amounts of high-fat foods, particularly fried foods or heavy dairy, can contribute to weight gain and insulin resistance, making it more difficult to control blood sugar even when taking Glycomet.
• Recommendation: Focus on a balanced diet that includes healthy fats from sources like olive oil, avocados, and nuts. Avoid foods that are fried or overly processed

Salt-Rich Foods

• Interaction: High-salt foods can negatively affect kidney function, which is crucial for eliminating Metformin from the body. Impaired kidney function may increase the risk of lactic acidosis.
• Recommendation: Limit the intake of foods high in sodium, such as processed foods, salty snacks, and fast food. Opt for fresh foods and use herbs or spices to flavor your meals instead.

More Information

FAQs About GLYCOMET 1GM TABLET

References

1. Metformin Prescribing Information USFDA. Revised on April 2017. [Accessed on 28th April 2025].  
2. Ranolazine Statpearls Revised on 17th August 2023. [Accessed on 28th April 2025].  
3. The effects of metformin on insulin resistance in overweight or obese children and adolescents: A PRISMA-compliant systematic review and meta-analysis of randomized controlled trials. Medicine®. Revised in January 2019. [Accessed on 28th April 2025].  
4. Effect of Low Glycemic Index Diet Versus Metformin on Metabolic Syndrome. NIH. National Library of Medicine. Revised in October 2015 [Accessed on 28th April 2025].  

Useful Diagnostic Tests

• Diabetes Profile- Comprehensive
• Advance Diabetes Care
• HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin

Author Details

Written By Srilekha. R - B.Pharm

Reviewed For Accuracy By Dr. Jaya Prabakaran - MBBS, MD (Diabetology and Family Medicine)

Last updated on 29 Apr 2025 | 06:14 PM(IST)