GLYCOFLO NEB Transpule 5x2ml
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Introduction About GLYCOFLO NEB TRANSPULE
GLYCOFLO NEB TRANSPULE contains Glycopyrrolate which belongs to the group of medicines called Anticholinergics. It is used for maintenance management of airflow obstruction in patients having chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease of the lung that causes congested airflow from the lungs. Symptoms of COPD include difficulty in breathing, cough, mucus (sputum) production and wheezing. It is usually caused by long-term exposure to irritating gases or particulate matter, most often from cigarette smoke.
Before using GLYCOFLO NEB TRANSPULE, inform your physician if you have kidney diseases, glaucoma, prostate or bladder problems or problems in passing urine. GLYCOFLO NEB TRANSPULE should be used with caution among pregnant and breastfeeding women only if clearly advised by the doctor. GLYCOFLO NEB TRANSPULE should not be used in children younger than 18 years of age.
The most common side effects of using GLYCOFLO NEB TRANSPULE are shortness of breath and urinary tract infections. Contact your physician if any of the symptoms worsen.
Uses Of GLYCOFLO NEB TRANSPULE
- manages chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema
How GLYCOFLO NEB TRANSPULE Works
GLYCOFLO NEB TRANSPULE works by blocking the action of a chemical messenger (acetylcholine) in the brain. This causes bronchodilation and helps the muscles around the lungs to stay relaxed and decreases COPD symptoms like coughing, chest tightness and shortness of breath.
How to use GLYCOFLO NEB TRANSPULE
Use GLYCOFLO NEB TRANSPULE as advised by your physician. It is for oral inhalational use only. It is administered by nebulization using with nebulizer (with a face mask or mouthpiece) which is connected to an air compressor. Your doctor will guide on how to use the nebulizer. Do not exceed the recommended dose of GLYCOFLO NEB TRANSPULE. Your doctor will decide the correct dose and duration of GLYCOFLO NEB TRANSPULE for you depending upon your age, body weight and disease condition.
Side Effects Of GLYCOFLO NEB TRANSPULE
Common
- shortness of breath
- urinary tract infections (strong urge to urinate that doesn't go away, burning feeling when urinating, frequent urination and passing small amounts of urine)
Rare
Stop using GLYCOFLO NEB TRANSPULE and contact your physician immediately if you experience any of the following side effects:
- sudden breathing problems or shortness of breath
- serious allergic reaction (symptoms include rash, hives, swelling of the tongue, lips and face and difficulty breathing or swallowing)
- acute narrow-angle glaucoma (symptoms include eye pain or discomfort, red eyes, blurred vision, seeing halos or bright colors around a light and nausea or vomiting)
- urinary retention (symptoms include difficulty urinating, painful urination, urinating frequently and urination in a weak stream or drips)
How To Manage Side Effects
Nausea:
Use this medicine with or just after meals. Stick to simple meals. Avoid eating rich or spicy food. Ask for your doctor’s advice if nausea doesn’t improve.
Vomiting:
Try and eat light, bland foods and avoid fried, oily or sweet foods. Ask for your doctor’s advice if vomiting doesn’t improve.
Warning & Precautions
Pregnancy
GLYCOFLO NEB TRANSPULE should be used with caution in pregnant women only if clearly advised by the doctor. Inform your doctor if you become pregnant while using GLYCOFLO NEB TRANSPULE. Consult your doctor before using.
Breastfeeding
GLYCOFLO NEB TRANSPULE should be used with caution in breastfeeding women only if clearly advised by the doctor as it is not known if GLYCOFLO NEB TRANSPULE passes through mother’s milk. Consult your doctor before using.
Driving and Using Machines
GLYCOFLO NEB TRANSPULE does not alter your ability to drive or use machines.
Kidney
GLYCOFLO NEB TRANSPULE should be used with caution in patients with kidney disease. Consult your physician before using it.
Allergy
Do not use GLYCOFLO NEB TRANSPULE if you are allergic to Glycopyrrolate or to any of the other ingredients of this medicine.
Others
Before using GLYCOFLO NEB TRANSPULE, inform your physician if you have:
- glaucoma (increased pressure within the eye)
- prostate or bladder problems
- problems in passing urine
Use in pediatrics:
GLYCOFLO NEB TRANSPULE is not recommended to use in children and adolescents younger than 18 years of age as the safety and effectiveness of GLYCOFLO NEB TRANSPULE has not been established in this group. Consult your physician before using it for your child.
Use in geriatrics:
No overall difference in safety or effectiveness of GLYCOFLO NEB TRANSPULE were observed between the elderly and younger patients. Consult your physician before using it.
Interactions
A. Drug-Drug interactions:
Before using GLYCOFLO NEB TRANSPULE, inform your physician if you are taking any of the following medicine:
- other anticholinergic drugs such as umeclidinium, tiotropium, ipratropium, aclidinium (used to manage asthma)
- sympathomimetics such as phenylephrine, pseudoephedrine (used in cough or cold)
- corticosteroids such as prednisolone (used to manage inflammation)
Overdosage:
If you or anyone else accidentally use too much of GLYCOFLO NEB TRANSPULE, consult your doctor immediately or visit the nearby hospital. The symptoms of overdosage are nausea, vomiting, dizziness, lightheadedness, blurred vision, increased intraocular pressure (causing pain, vision disturbances or reddening of the eye), obstipation (severe form of constipation) or difficulties in voiding (urination).
Synopsis
| Drug | : | Glycopyrrolate |
| Pharmacological Category | : | Anticholinergics |
| Therapeutic Indication | : | COPD (Chronic Pulmonary Obstructive Disease) |
| Dosage Forms | : | Tablet, Injection, Respules, Transpule |
More Information
- Keep GLYCOFLO NEB TRANSPULE out of reach of children
- Store GLYCOFLO NEB TRANSPULE at a temperature, not more than 25°C
FAQs About GLYCOFLO NEB TRANSPULE
Why is GLYCOFLO NEB TRANSPULE prescribed to me?
GLYCOFLO NEB TRANSPULE is used maintenance management of airflow obstruction in patients having chronic obstructive pulmonary disease (COPD), including chronic bronchitis or emphysema. Consult your physician before using GLYCOFLO NEB TRANSPULE.
How to take GLYCOFLO NEB TRANSPULE?
Take GLYCOFLO NEB TRANSPULE as advised by your physician. It is for oral inhalational use only. It is administered by nebulization using with nebulizer (with a face mask or mouthpiece) which is connected to an air compressor. Your doctor will guide on how to use the nebulizer. Do not exceed the recommended dose of GLYCOFLO NEB TRANSPULE. Your doctor will decide the correct dose and duration of GLYCOFLO NEB TRANSPULE for you depending upon your age, body weight and disease condition.
What are the common side effects of GLYCOFLO NEB TRANSPULE?
The most common side effects of using GLYCOFLO NEB TRANSPULE are shortness of breath and urinary tract infections. Contact your physician for advice if any of the symptoms worsen.
What happens if I use more GLYCOFLO NEB TRANSPULE?
If you or anyone else accidentally use too much of GLYCOFLO NEB TRANSPULE, consult your doctor immediately or visit the nearby hospital. The symptoms of overdosage are nausea, vomiting, dizziness, lightheadedness, blurred vision, increased intraocular pressure (causing pain, vision disturbances or reddening of the eye), obstipation or difficulties in voiding.
Is it safe to drive after using GLYCOFLO NEB TRANSPULE?
GLYCOFLO NEB TRANSPULE has no or negligible influence on the ability to drive and use machines. However, ask for your physician’s advice.
Is GLYCOFLO NEB TRANSPULE a steroid?
GLYCOFLO NEB TRANSPULE belongs to the group of medicines called Anticholinergics. It works by blocking the action of a chemical messenger (acetylcholine) in the brain. This helps the muscles around the lungs stay relaxed and decreases COPD symptoms like coughing, chest tightness and shortness of breath.
Can I stop taking GLYCOFLO NEB TRANSPULE on my own if I start to feel better?
Do not stop using GLYCOFLO NEB TRANSPULE or other medicines to control or manage your COPD unless told to do so by your doctor because your symptoms might get worse. If you wish to discontinue using GLYCOFLO NEB TRANSPULE, ask for your doctor’s advice.
References
1. Holly E. Gurgle and Donald K. Blumenthal. Drug Therapy for Dyslipidemias. Goodman & Gilman’s The Pharmacological basics of Therapeutics. 13th Edition. New York McGraw Hill Medical 2018. Page – 605-618.
2. Pierachille Santus, Dejan Radovanovic, Andrea Cristiano, Vincenzo Valenti and Maurizio Rizzi. Role of nebulized glycopyrrolate in the treatment of chronic obstructive pulmonary disease. NIH National Library of Medicine National Centre for Biotechnology Information. Pumed Central. November 2017. [Accessed on 6th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695264/
3. Donald P Tashkin, Nicholas J Gross. Inhaled glycopyrrolate for the treatment of chronic obstructive pulmonary disease. International Journal of Chronic Obstructive Pulmonary Disease. NIH National Library of Medicine National Centre for Biotechnology Information. Pumed Central. June 2018 [Accessed on 6th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003532
4. Edward Kerwin, James F. Donohue, ThomasGoodin, RobertTosiello, Alistair Wheeler, Gary T.Ferguson. Efficacy and safety of glycopyrrolate / eFlow® CS (nebulized glycopyrrolate) in moderate-to-very-severe COPD: Results from the glycopyrrolate for obstructive lung disease via electronic nebulizer (GOLDEN) 3 and 4 randomized controlled trials. Journal of Respiratory Medicine. Science Direct. November 2017. [Accessed on 6th July 2022] https://www.sciencedirect.com/science/article/pii/S095461111730210X
5. Glycopyrrolate. https://www.ciplamed.com/. [Revised in November 2019] [Accessed on 6th July 2022] https://www.ciplamed.com/content/glycohale-respule
6. Sunovion Pharmaceuticals Inc. Dailymed. [Revised in December 2020] [Accessed on 6th July 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=78166def-5e2f-42a6-a1f1-0253e5765632
7. Drug bank. Glycopyrrolate. [Accessed on 6th July 2022] https://go.drugbank.com/drugs/DB00986
Useful Diagnostic Tests
- Chest X ray
- Pulmonary Function Test
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