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Introduction About GEMITROL KIT
GEMITROL KIT is a combination of Calcitriol, Calcium Carbonate, Risedronate, and Zinc, which belong to the group of medicines called Vitamin D metabolites, Minerals and Bone Conserving Agents respectively. GEMITROL KIT is indicated in the management of osteoporosis in postmenopausal women.
Prior to the management with GEMITROL KIT, your doctor might ask you to take some diagnostic tests.
Before taking GEMITROL KIT, inform your doctor if you have kidney diseases, stomach or digestive problems, problems swallowing, difficulty in movement such as after an operation, low blood calcium, difficulty in absorption, and plan to undergo dental surgery.
GEMITROL KIT is not recommended for use in patients with high levels of calcium in the blood, extra deposits of calcium in the body, abnormalities of the esophagus, and an inability to stand or sit upright.
GEMITROL KIT should be used with caution in pregnant and breast-feeding women. GEMITROL KIT is not intended for use by children.
The most common side effects of taking GEMITROL KIT are pain, including back and joint pain, stomach pain, and heartburn. Ask for your doctor’s advice if any of these worsen or don’t improve.
Uses Of GEMITROL KIT
- To manage osteoporosis in postmenopausal women
How GEMITROL KIT Works
GEMITROL KIT is used to manage osteoporosis, where calcitriol enhances the absorption of dietary calcium and phosphate from the gastrointestinal tract and kidneys and helps stimulate the release of calcium stores from the skeletal system, which improves calcium regulation in the blood. Calcium carbonate directly increases calcium stores in the body. Risedronate is a bisphosphonate that acts on the bone-resorbing cells called osteoclasts and inhibits their activity. It also aids in bone mineralization and regeneration. Zinc helps in restoring bone health by managing bone resorption.
How to use GEMITROL KIT
Take GEMITROL KIT as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Do not lie down for at least 30 minutes after you take GEMITROL KIT and after you eat your first meal of the day. Your doctor will decide the correct dose and duration of GEMITROL KIT for you depending upon your age, body weight, and disease condition.
Side Effects Of GEMITROL KIT
Common
- back and joint pain
- stomach pain
- heartburn
Rare
- signs of high levels of calcium in your blood such as loss of appetite, weight loss, nausea, vomiting, headache, and feeling sluggish, drowsy, or weak
- mental problems
- kidney stones
- changes in kidney function
Warning & Precautions
Pregnancy
Use with CautionGEMITROL KIT should be used with caution in pregnant women. Consult your doctor before taking it.
Breastfeeding
Use with CautionGEMITROL KIT should be used with caution in breast-feeding women. Consult your doctor before taking it.
Driving and Using Machines
Use with CautionGEMITROL KIT does not impair your ability to drive or use machines.
Kidney
Use with CautionGEMITROL KIT should be used with caution in patients with kidney diseases. Consult your doctor before taking.
Allergy
ContraindicatedDo not take GEMITROL KIT if you are allergic to Calcitriol, Calcium Carbonate, Risedronate, and zinc.
Use In Pediatrics
ContraindicatedGEMITROL KIT is not recommended for use in children under 18 years of age. Consult your doctor before taking
Use In Geriatrics
Consult your doctorYour doctor will decide the correct dose and duration of the management with GEMITROL KIT for you depending upon your age, health condition, and body weight. Consult your doctor.
Others
GEMITROL KIT is not recommended for use if you:
- have increased levels of calcium in the blood (hypercalcemia)
- have more deposits of calcium in your body
- have abnormalities of the esophagus causing delayed oesophageal emptying, such as stricture or achalasia
- are unable to stand or sit upright for at least 30 minutes
Before taking GEMITROL KIT, tell your doctor if you:
- have stomach or digestive problems
- have problems with swallowing
- have difficulty in movement, such as after an operation
- have low blood calcium
- have difficulty with absorption
- plan to undergo dental surgery
Interactions
A. Drug-Drug Interactions:
Inform your physician if you are taking any of the following drugs before taking GEMITROL KIT:
- other medicines containing Vitamin D
- diuretics (water tablets) such as bendroflumethiazide, chlortalidone, and indapamide (used to manage high blood pressure) and digoxin (used to manage heart diseases)
- antacids such as magnesium sulphate (used to manage indigestion)
- steroids such as hydrocortisone, prednisolone, and dexamethasone (used to manage pain and inflammation)
- cholestyramine (used in managing high levels of cholesterol)
- ergocalciferol, cholecalciferol (used in the management of low calcium levels in the blood)
B. Drug-food interactions:
- avoid taking any vitamins or food supplements that contain vitamin D
- avoid eating foods rich in vitamin D
Overdosage:
If you or anyone else accidentally takes too much of GEMITROL KIT, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : |
Calcitriol, Calcium Carbonate, Risedronate, and zinc |
| Pharmacological Category | : |
Vitamin D metabolites, Minerals, Bisphosphonates |
| Therapeutic Indication | : | Osteoporosis in Postmenopausal Women |
| Dosage Forms | : | Kit |
More Information
- Keep GEMITROL KIT out of reach of children
- Store GEMITROL KIT below 25°C
FAQs About GEMITROL KIT
Q: What is GEMITROL KIT and why is it prescribed?
A: GEMITROL KIT is a combination of Calcitriol, Calcium Carbonate, Risedronate, and Zinc, which belong to the group of medicines called Vitamin D metabolites, Minerals and Bone Conserving Agents, respectively. GEMITROL KIT is indicated in the management of osteoporosis in postmenopausal women.
Q: Can GEMITROL KIT affect oral health?
A: Patients taking GEMITROL KIT should take care of their oral hygiene. If, after taking GEMITROL KIT, they have any symptoms like loosening of teeth, pain in the mouth or jaw, delayed wound healing, or infection after extraction, they should immediately talk to their doctor.
Q: Is GEMITROL KIT safe for use in pregnant and breast-feeding women?
A: GEMITROL KIT should be used with caution in pregnant and breast-feeding women. Consult your doctor before taking it.
Q: What are the dietary instructions that need to be followed while taking GEMITROL KIT?
A: Avoid the consumption of vitamins or food supplements that contain vitamin D while you are taking GEMITROL KIT. Avoid eating foods that have vitamin D added. It is very important to keep following the diet that your doctor has given you. If you change the amount of calcium or vitamin D you have in your diet while taking GEMITROL KIT, this can increase the risk of side effects. Also, drink plenty of water and other fluids to keep yourself hydrated.
Q: What precautions should I follow while taking GEMITROL KIT?
A: Take GEMITROL KIT as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Do not lie down for at least 30 minutes after you take GEMITROL KIT and after you eat your first meal of the day.
References
1. KD. Tripathi. Drugs Affecting Calcium Balance. Essentials of medical pharmacology. Seventh edition. 2013. Page – 336, 341 & 344.
2. John K Brooks, Allen J Gilson, Arnold J Sindler, Steven G Ashman, Kevin G Schwartz, Nikolaos G Nikitakis. Osteonecrosis of the jaws associated with use of risedronate: report of 2 new cases. NIH. National Library of Medicine, National center for biotechnology information. Pubmed.gov. June 2007. [Accessed on 7th February 2024] https://pubmed.ncbi.nlm.nih.gov/17223592/
3. Sandeep Kalra, Veena Jain. Dental complications and management of patients on bisphosphonate therapy: A review article. NIH. National Library of Medicine, National center for biotechnology information. PubMed.gov. November 2012. [Accessed on 7th February 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942225/
4. Masayoshi Yamaguchi. Role of nutritional zinc in the prevention of osteoporosis. NIH. National Library of Medicine, National center for biotechnology information. PubMed.gov. May 2010. [Accessed on 7th February 2024] https://pubmed.ncbi.nlm.nih.gov/20035439/
5. NIH. National Library of Medicine, National center for biotechnology information. PubChem. Risedronate Sodium. [Accessed on 7th February 2024] https://pubchem.ncbi.nlm.nih.gov/compound/Risedronate-sodium
6. Torrent Pharmaceuticals Ltd. Gemitrol Kit. [Revised in January 2020]. [Accessed on 7th February 2024] https://www.torrentian.com/pisheet/Upload/PI_Sheet/1083.pdf
7. Drug Bank. Calcitriol. [Accessed on 7th February 2024] https://go.drugbank.com/drugs/DB00136
8. Drug Bank. Calcium Carbonate. [Accessed on 7th February 2024] https://go.drugbank.com/drugs/DB06724
Useful Diagnostic Tests
- Calcium
- Vitamin D 1,25 Dihydroxy
- Extended Arthritis Care
- Comprehensive Arthritis Care
- Basic Bone Care
- Advance Bone Care
- Comprehensive Bone Care
- Esr Automated
- Phosphorus-Inorganic, Serum
- Basic Arthritis Care Plan
- Bone Strength Package
- Arthritis Profile-Basic
- Arthritis Profile-Advanced
- Pth-Intact Molecule Parathyroid Hormone
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