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Introduction About GANTRA 2.5MG TABLET
GANTRA 2.5mg Tablet is used to manage adults with long-term heart failure who have had a recent hospitalization or the need to receive intravenous (IV) medicines and have an ejection fraction (amount of blood pumped with each heartbeat) of less than 45 percent to reduce the risk of dying and to reduce the need to be hospitalized.
GANTRA 2.5mg Tablet contains Vericiguat, which belongs to the group of medicines called Soluble guanylate cyclase stimulators. It works by helping blood vessels relax, improving blood flow, and reducing the strain on the heart, which is particularly beneficial for patients with chronic heart failure.
Do not take GANTRA 2.5mg Tablet if you are allergic to Vericiguat or any other ingredients in this medicine. GANTRA 2.5mg Tablet should be used with caution if you have severe liver failure, severe kidney disease, are on dialysis, have low blood pressure (symptoms include dizziness and lightheadedness), or have an intolerance to some sugars. Consult your doctor before taking it.
GANTRA 2.5mg Tablet should not be used during pregnancy, as it is not known if it harms the unborn baby. GANTRA 2.5mg Tablet is not recommended for use in breastfeeding women as it is not known if GANTRA 2.5mg Tablet passes into your breast milk and could harm your baby. Consult your doctor before taking it.
GANTRA 2.5mg Tablet is not recommended for use in children and adolescents under 18 years of age, as safety and efficacy are not established in this age group. The most common side effect of taking a GANTRA 2.5mg Tablet is low blood pressure (hypotension). Consult your doctor if any of the side effects worsen.
Uses Of GANTRA 2.5MG TABLET
- To manage adults with long-term heart failure who have recently had an increase in heart failure symptoms
How GANTRA 2.5MG TABLET Works
Vericiguat works by helping blood vessels relax, improving blood flow, and reducing the strain on the heart, which is particularly beneficial for patients with chronic heart failure.
How to use GANTRA 2.5MG TABLET
Take GANTRA 2.5mg Tablet as advised by your physician. Swallow the whole tablet with a glass of water, and do not crush or chew the tablet. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and severity of the condition.
Take one tablet at the same time each day with food. If you cannot swallow the tablet, you may crush the tablet and mix it with water. Take this mixture immediately. Do not stop taking this medication without consulting with your doctor.
Side Effects Of GANTRA 2.5MG TABLET
Common
- Low blood pressure (hypotension)
- low number of red blood cells (anaemia), which can cause pale skin, weakness, or breathlessness.
- dizziness
- headache
- nausea and vomiting
- indigestion (dyspepsia)
- heartburn (gastro-oesophageal reflux disease)
How To Manage Side Effects
Dizziness Or Drowsiness
Ensure proper hydration, as dehydration can cause dizziness. Avoid excessive caffeine, alcohol, and high-sodium foods, which can exacerbate symptoms. Engage in physical therapy or vestibular rehabilitation exercises designed to improve balance and reduce dizziness. Move slowly when changing positions, such as standing up or lying down, to avoid triggering dizziness. Practice relaxation techniques such as deep breathing, meditation, or yoga to manage stress, which can contribute to dizziness. Consult your doctor if dizziness persists.
Headache
Ensure adequate fluid intake, as dehydration can cause headaches. Maintain a consistent sleep schedule, aiming for 7-9 hours of quality sleep per night. Eat balanced meals at regular intervals to avoid blood sugar fluctuations that can trigger headaches. Practice relaxation techniques such as meditation, yoga, or deep breathing exercises to reduce stress levels. Engage in regular physical exercise, which can help reduce the frequency and severity of headaches. Apply a cold pack or warm compress to the forehead or neck to alleviate pain. Consult your doctor if a headache persists.
Indigestion
Avoid trigger foods such as fatty, spicy, or acidic items. Eating slowly, chewing food thoroughly, and avoiding lying down immediately after meals can improve digestion. Reduce stress through relaxation techniques like meditation, yoga, or deep breathing, which can alleviate symptoms. Maintaining a healthy weight, quitting smoking, and limiting alcohol consumption are also beneficial. Drinking plenty of water helps digestion. Engaging in regular physical activity can help keep the digestive system active and reduce stress, which may improve symptoms. Consult your doctor if indigestion persists.
Nausea And Vomiting
Stay hydrated with small sips of clear fluids like water, ginger ale, or electrolyte solutions. Avoid consuming large meals; instead, opt for bland, easy-to-digest foods. Ginger, peppermint, or chamomile tea may help soothe the stomach. Rest in a comfortable position, preferably with your head elevated, to ease symptoms. Consult your doctor if nausea and vomiting persist.
Warning & Precautions
Pregnancy
ContraindicatedGANTRA 2.5mg Tablet should not be used during pregnancy, as it is not known if it harms the unborn baby. Females of reproductive potential should use effective contraception during treatment with this medicine and for at least one month after the final dose. Consult your doctor before taking it.
Breastfeeding
ContraindicatedGANTRA 2.5mg Tablet is not recommended for use in breastfeeding women as it is not known if GANTRA 2.5mg Tablet passes into your breast milk and could harm your baby. Your doctor will decide with you whether breast-feeding or GANTRA 2.5mg Tablet should be stopped.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel dizzy after taking GANTRA 2.5mg Tablet.
Kidney
Use with CautionGANTRA 2.5mg Tablet should be used with caution if you have severe kidney disease or are on dialysis. Consult your doctor before taking it.
Liver
Use with CautionGANTRA 2.5mg Tablet should be used with caution if you have severe liver failure. Consult your doctor before taking it.
Allergy
ContraindicatedDo not take GANTRA 2.5mg Tablet if you are allergic to vericiguat or any other ingredients in this medicine.
Heart Disease
Use with CautionGANTRA 2.5mg Tablet should be used with caution in patients with low blood pressure (symptoms include dizziness and lightheadedness). Consult your doctor before taking it.
Use In Pediatrics
ContraindicatedGANTRA 2.5mg Tablet is not recommended for use in children and adolescents under 18 years of age, as safety and efficacy are not established in this age group.
Use In Geriatrics
Use with CautionGANTRA 2.5mg Tablet should be used with caution in elderly patients aged 65 years and older. Consult your doctor before taking it.
Others
Before taking GANTRA 2.5mg Tablet, inform your doctor if you have:
- Intolerance to some sugars
Interactions
A. Drug-drug interactions:
- Other soluble guanylate cyclase stimulators (Ex. riociguat)
- PDE5 inhibitors (Ex. sildenafil, tadalafil, and vardenafil)
- Nitrates (Ex. isosorbide mononitrate)
Overdosage:
If you or anyone else accidentally takes too much of GANTRA 2.5mg Tablet, consult your doctor immediately or visit the nearby hospital. Signs and symptoms include low blood pressure, which can make you feel dizzy and light-headed.
Synopsis
| Drug | : | Vericiguat |
| Pharmacological Category | : | Soluble guanylate cyclase stimulator |
| Therapeutic Indication | : | To manage long-term heart failure |
| Dosage Forms | : | Tablet |
More Information
Storage
- Keep GANTRA 2.5mg Tablet out of reach of children
- Store below 25°C
FAQs About GANTRA 2.5MG TABLET
Q: What is the use of the GANTRA 2.5mg Tablet?
A:GANTRA 2.5mg Tablet is used to manage adults with long-term heart failure who have had a recent hospitalization or the need to receive intravenous (IV) medicines and have an ejection fraction (amount of blood pumped with each heartbeat) of less than 45 percent to reduce the risk of dying and to reduce the need to be hospitalized.
Q: What if I forget to take the GANTRA 2.5mg Tablet?
A: Take the missed tablet as soon as you remember on the same day of the missed dose. Do not take a double dose to make up for a forgotten tablet.
Q: How should I take GANTRA 2.5mg Tablet?
A:Take the GANTRA 2.5mg Tablet as advised by your physician. Swallow the whole tablet with a glass of water, and do not crush or chew the tablet. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and severity of the condition. Take one tablet at the same time each day with food. If you cannot swallow the tablet, you may crush the tablet and mix it with water. Take this mixture immediately. Do not stop taking this medication without consulting with your doctor.
Q: How does the GANTRA 2.5mg Tablet work?
A: Vericiguat works by helping blood vessels relax, improving blood flow, and reducing the strain on the heart, which is particularly beneficial for patients with chronic heart failure.
Q: What are the side effects of the GANTRA 2.5mg Tablet?
A: The most common side effect of taking GANTRA 2.5mg Tablet is low blood pressure (hypotension). Consult your doctor if any of the side effects worsen.
Q: Is GANTRA 2.5mg Tablet safe during pregnancy?
A:GANTRA 2.5mg Tablet should not be used during pregnancy, as it is not known if they harm the unborn baby. Females of reproductive potential should use effective contraception during treatment with this medicine and for at least one month after the final dose. Consult your doctor before taking it.
Q: Can GANTRA 2.5mg Tablet be used in children?
A:GANTRA 2.5mg Tablet is not recommended for use in children and adolescents under 18 years of age, as safety and efficacy are not established in this age group.
Q: What precautions must be taken while using the GANTRA 2.5mg Tablet?
A:GANTRA 2.5mg Tablet should be used with caution if you have severe liver failure, severe kidney disease, are on dialysis, have low blood pressure (symptoms include dizziness and lightheadedness), or have an intolerance to some sugars. Consult your doctor before taking it.
Q: Who should not take GANTRA 2.5mg Tablet?
A: Do not take GANTRA 2.5mg Tablet if you are allergic to vericiguat or any other ingredients in this medicine.
Q: Can I take other medicines while taking GANTRA 2.5mg Tablet?
A: Before taking GANTRA 2.5mg Tablet, inform your doctor about the medicines you are taking, including prescription, non-prescription, and herbal medicines.
Q: Can I buy GANTRA 2.5mg Tablet online?
A: Yes, GANTRA 2.5mg Tablet can be purchased online from various online pharmacies, like Netmeds in India. If you wish to buy GANTRA 2.5mg Tablet on Netmeds, you need a prescription from a registered medical practitioner. Netmeds has made buying online medicines more easy for consumers and is one of India's leading online pharmacies.
References
1. Ankit Vyas; Nirmal Onteddu. Vericiguat. NIH, National Library of Medicine. National Centre for Biotechnology Information. StatPearls. August 2023. [Accessed on 28th June 2024] https://www.ncbi.nlm.nih.gov/books/NBK574528/
2. Bayer plc. Electronic Medicines Compendium (EMC). [Revised in March 2023] [Accessed on 28th June 2024] https://www.medicines.org.uk/emc/files/pil.12773.pdf
3. Merck & Co., Inc., U.S. Food & Drug Administration. [Revised in January 2021] [Accessed on 28th June 2024] https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/214377s000lbl.pdf
Useful Diagnostic Tests
- Complete Blood Count (CBC)/ Hemogram
- Cardiac Risk Profile
- C Reactive Protein (CRP)
- Basic Heart Care
- Extended Heart Care
- Advance Heart Care
- Comprehensive Heart Care
- Netmeds Healthy Heart
- Cardiac Risk Markers - Advanced
- Hplus Comprehensive Heart Care
- Hplus Advanced Heart Care
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