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Introduction About FUSINOL PLUS CREAM
FUSINOL PLUS CREAM is a combination of Clobetasol, Fusidic acid, and Clotrimazole which belong to a group of medicines called Topical Corticosteroids, Oral antistaphylococcal antibiotic, and Imidazoles respectively. FUSINOL PLUS CREAM is used in the topical management of a wide variety of bacterial and fungal skin infections with associated inflammation in resistant and/or secondary bacterial infections.
A bacterial infection occurs when a bacteria enters the body, multiplies, and causes a reaction in the body that leads to infection, which is characterised by symptoms such as difficulty breathing, persistent cough and fever, unexplained redness and/or swelling of the skin, and frequent vomiting. A fungal infection is a skin disease caused by a fungus that leads to infection and is associated with symptoms such as irritation, scaly skin, redness, itching, and swelling.
Avoid applying FUSINOL PLUS CREAM if you are allergic to Clobetasol, Fusidic acid, or Clotrimazole. Before applying FUSINOL PLUS CREAM, inform your doctor if you are a smoker, have concomitant skin infections (parasitic infections), or plan to apply the medicine near the eyes.
FUSINOL PLUS CREAM should be used with caution during pregnancy and in breastfeeding women only if it is necessary, which is not recommended for use in children and adolescents (below 12 years of age). The most common symptoms of applying FUSINOL PLUS CREAM are a burning or stinging sensation and itchy skin. Consult your doctor if any of these symptoms get worse.
Uses Of FUSINOL PLUS CREAM
- Manage a wide variety of bacterial & fungal skin infections with associated inflammation in resistant and or secondary bacteria infection
How FUSINOL PLUS CREAM Works
FUSINOL PLUS CREAM helps to manage a wide variety of bacterial and fungal skin infections. Clobetasol manages inflammation by blocking the production of certain chemical messengers (prostaglandins) that make the skin red, swollen, and itchy. Fusidic Acid manages the growth of bacteria and causes its destruction by inhibiting the synthesis of essential proteins that are essential for the bacteria to grow.
How to use FUSINOL PLUS CREAM
Always apply FUSINOL PLUS CREAM, as directed by your physician. It is for external use only. On the affected area, apply a thin layer of this medicine. Managed areas on the face need not be covered with a plaster or bandage. Do not apply FUSINOL PLUS CREAM on your face beyond 5 days. Avoid applying FUSINOL PLUS CREAM around your eyes, including eyelids.
Side Effects Of FUSINOL PLUS CREAM
Common
- burning and stinging sensation
- itchy skin
Uncommon
- skin atrophy (thin, shiny skin)
- cracking and fissuring of the skin
- erythema (skin redness)
- folliculitis (inflammation of hair follicle)
- numbness of fingers
- telangiectasia (a condition marked by dilated small blood vessels on the skin or mucous membrane)
- signs of skin irritation at the site of application such as pain, and skin redness
- rash
- skin inflammation
Rare
- pink eye
- red, itchy skin
- skin swelling
- blistering of the skin
Stop applying FUSINOL PLUS CREAM and contact your doctor if you experience any of the following side effects:
- irritation at the site of application
- signs of an allergic reaction such as difficulty in breathing, swollen face /lips/tongue or throat, severe rash, weakness, feeling dizzy /faint, and nausea
How To Manage Side Effects
Dry Skin:
Try moisturising your skin with an ointment, cream, or lotion two or three times a day, or as often as needed. Moisturizers help to keep the area moist, so they work best on damp skin. After you bathe, pat your skin dry, then apply your moisturizer. Try to avoid using skin care products and soaps that contain alcohol, fragrances, dyes, or other chemicals.
Warning & Precautions
Pregnancy
FUSINOL PLUS CREAM should be used with caution during pregnancy and in women planning for pregnancy only if it is necessary. Consult your doctor before applying FUSINOL PLUS CREAM.
Breastfeeding
FUSINOL PLUS CREAM should be used with caution in breastfeeding women only if it is necessary. Consult your doctor before applying FUSINOL PLUS CREAM.
Driving and Using Machines
FUSINOL PLUS CREAM should not affect your ability to drive or operate machines. Consult your doctor before applying FUSINOL PLUS CREAM.
Allergy
FUSINOL PLUS CREAM is not recommended for use if you are allergic to Clobetasol, Fusidic acid, Clotrimazole or any other ingredients of this medicine.
Others
Before applying FUSINOL PLUS CREAM, inform your doctor if you:
- have concomitant skin infections (parasitic infections)
- are planning to apply for medicine near eyes
- are a smoker
Use in Pediatrics:
FUSINOL PLUS CREAM is not recommended for use in children and adolescents (below 12 years). Consult your doctor before applying FUSINOL PLUS CREAM.
Use in Geriatrics:
FUSINOL PLUS CREAM should be used with caution in elderly patients (aged 65 years or above). Consult your doctor before applying FUSINOL PLUS CREAM.
Interactions
A. Drug-Drug Interactions:
Before applying FUSINOL PLUS CREAM, inform your doctor, if you are using or taking any prescription, non-prescription or herbal medicines.
Overdosage:
If you or anyone else accidentally apply too much FUSINOL PLUS CREAM, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are corticosteroid-related dermatitis (a skin disorder that occurs due to prolonged use of corticosteroids), HPA axis suppression (a condition that causes poor body defense against infection), Cushing’s syndrome (hormonal disorder), hyperglycemia (high blood sugar) and glucosuria (low sugar in urine).
Synopsis
| Drug | : | Clobetasol, Fusidic acid, Clotrimazole |
| Pharmacological Category | : | Topical Corticosteroids, Oral antistaphylococcal antibiotic, Imidazoles |
| Therapeutic Indication | : | Bacterial & fungal skin infections with associated inflammation |
| Dosage Forms | : | Cream |
More Information
- Keep FUSINOL PLUS CREAM out of reach from children
- Store FUSINOL PLUS CREAM at room temperature
FAQs About FUSINOL PLUS CREAM
Q: What is the function of FUSINOL PLUS CREAM?
A: FUSINOL PLUS CREAM is used in the topical management of a wide variety of bacterial and fungal skin infections with associated inflammation in resistant and/or secondary bacterial infections.
Q: What happens if you forget to apply FUSINOL PLUS CREAM?
A: If you forget to apply FUSINOL PLUS CREAM, then try to apply it as soon as you remember. If the time is right for the next application, then carry on as normal. Try to remember to apply FUSINOL PLUS CREAM as per its application time to avoid the risks of returning infection.
Q: What are the side effects of applying FUSINOL PLUS CREAM?
A: FUSINOL PLUS CREAM causes side effects such as burning and stinging sensations, itchy skin, skin atrophy (thin, shiny skin), cracking and fissuring of the skin, and erythema (skin redness), with the most frequently occurring side effects noted to be burning and stinging sensations on the applied site. Consult your doctor if any of these symptoms get worse.
Q: Who should avoid applying FUSINOL PLUS CREAM?
A: FUSINOL PLUS CREAM is not recommended for use in patients allergic to Clobetasol, Fusidic acid, or Clotrimazole, which is also not recommended for use in children and adolescents (below 12 years of age). Consult your doctor before applying FUSINOL PLUS CREAM.
Q: Is FUSINOL PLUS CREAM safe to be used by pregnant and breastfeeding women?
A: FUSINOL PLUS CREAM should be used with caution during pregnancy and in lactating women only if necessary. Consult your doctor before applying FUSINOL PLUS CREAM.
References
1. KD Tripathi. Drugs Acting on Skin & Mucous Membranes; Macrolide, Lincosamide, Glycopeptide & Other Antibacterial Antibiotics; Urinary Antiseptics, and Antifungal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 759, 792, & 895.
2. Olga Kiselova, Baiba Maurina, and Venta Šidlovska. Analysis of Extemporaneous Prescriptions Prescribed by Dermatovenerologists in Latvia and Comparison with Standardized Compounded Preparation Monographs of Germany and USA. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in January 2020] [Accessed on 25th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023179/
3. Clobetasol propionate. NIH. National Library of Medicine. National Center for Biotechnology Information. PubChem. [Revised in July 2022] [Accessed on 25th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Clobetasol-propionate#section=Biological-Half-Life
4. Prabhavathi Fernandes.Fusidic Acid: A Bacterial Elongation Factor Inhibitor for the Oral Treatment of Acute and Chronic Staphylococcal Infections. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in January 2016] [Accessed on 25th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691801/
5. Neil J. Khatter; Moien AB Khan. Clotrimazole. NIH National Library of Medicine. National Center for Biotechnology Information. StatPearls. [Revised in July 2021] [Accessed on 25th June 2022] https://www.ncbi.nlm.nih.gov/books/NBK560643/#:~:text=Go%20to%3A-,Mechanism%20of%20Action,demethylation%20of%2014%20alpha%20lanosterol
6. Clobetasol propionate cream usp, 0.05%. DailyMed. NIH U.S.National Library of Medicine. May 2022. [Accessed on 25th June 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=98b23b99-fab4-49fb-b070-758fb030e9bb
7. LEO Laboratories Limited. Electronic medicines compendium (EMC). [Revised in November 2019] [Accessed on 25th June 2022] https://www.medicines.org.uk/emc/files/pil.5510.pdf
8. Mylan UK Healthcare Limited. Electronic medicines compendium (EMC). [Revised in February 2022] [Accessed on 25th June 2022] https://www.medicines.org.uk/emc/files/pil.2598.pdf
9. Leeford. Fusinol plus. [Revised in 2022] [Accessed on 24th June 2022] https://www.leeford.in/product/1272/fusinol-plus
Useful Diagnostic Tests
- Bacteria Culture Test
- Blood test
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