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Introduction About FLOXITRU P EYE DROPS
FLOXITRU P EYE DROPS is a combination of Moxifloxacin and Prednisolone which belongs to the group of medicines called Antibiotics and Corticosteroids respectively. It is used to manage eye inflammation and infection.
It also helps in reducing eye pain, redness, itching and/or burning or stinging sensation following eye surgery (such as cataract or corneal refractive surgery). It is typically used in conditions which involves the risk of both eye inflammation and infection such as during injuries or post-surgery.
Use this medicine exactly as instructed by your physician. Misuse or overuse of this medicine may lead to unwanted side effects. If there is no improvement in your condition even after using this medicine for 7 days, consult your doctor for advice.
If you wear soft contact lenses, remove the lens before applying FLOXITRU P EYE DROPS and wait for at least 15 minutes before reinsertion.
Before using FLOXITRU P EYE DROPS inform your doctor if you have severe viral or fungal eye infections. You must also inform your doctor if you have glaucoma or any holes or ulcerations in the eyes as a precaution.
Do not use FLOXITRU P EYE DROPS without consulting your doctor if you are pregnant or breastfeeding. The most common side effects of using FLOXITRU P EYE DROPS are mild eye irritation or burning sensation, blurred vision, increased eye pressure, headache and taste changes. Consult your doctor if any of these side effect worsens.
Uses Of FLOXITRU P EYE DROPS
- Manage and manages eye infection and inflammation
- Reduces eye pain, redness, itching or burning/stinging sensation following eye surgery
How FLOXITRU P EYE DROPS Works
FLOXITRU P EYE DROPS contains two medicines namely, Prednisolone and Moxifloxacin. Prednisolone is a steroid medication. It blocks the release of certain chemicals in the body (such as prostaglandins) that causes inflammation, redness and swelling. When applied topically on the eyes, it reduces eye redness, soreness, pain, itching and swelling.
Moxifloxacin is an antibiotic. When applied topically on the eyes, it kills the susceptible bacteria that causes eye infection. Collectively, this medicine reduces inflammation and infection of the eyes.
How to use FLOXITRU P EYE DROPS
Use FLOXITRU P EYE DROPS as advised by your physician. It is for ophthalmic use only. Tilt your head slightly backwards and gently pull your lower eyelid. Instil few drops of this medicine into the eyes and close your eyes for 2 minutes. Repeat the same for the other eye if required. If you wear soft contact lenses, remove the lens before applying FLOXITRU P EYE DROPS and wait for at least 15 minutes before reinsertion.
Wash your hands before and after application. Do not touch the tip of the container with your eyes, eyelids, areas around your eyes, outer surface of the ears or fingers, to avoid contamination. Leave a time gap of at least 5 minutes between this medicine and other eye medicines.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. If there is no improvement in your condition even after using this medicine for 7 days, consult your doctor for advice.
Side Effects Of FLOXITRU P EYE DROPS
Common
- eye pain or irritation
- sensation of a foreign particles in the eyes
- headache
- mild burning or stinging sensation in the eyes
- cloudy eyes, blurred vision
- dilated pupils
- changes in taste
- increased pressure within the eyes
Uncommon
- dry eyes
- eye redness
- eye surface inflammation
- dropping eyelids
Rare
- vomiting
- nasal discomfort
- abnormal skin sensation
- pain, throat irritation
Stop using FLOXITRU P EYE DROPS and contact your doctor immediately if you experience any of the following side effects:
- severe allergic reactions (such as skin rash, itching, swelling of the face, lips, throat, tongue causing difficulty in breathing or swallowing)
- severe skin reactions with blistering and peeling of skin
- severe eye pain, redness, irritation and vision changes
- pain or swelling of tendons
How To Manage Side Effects
Eye pain or irritation:
Wash your eyes with plain cold water. Place an ice pack on your eye to ease the irritation. Avoid straining your eyes by looking at mobile phones, laptops or television. Wear protective eyeglasses while going outdoors.
Headache:
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Blurred vision:
Close your eyes and relax. Do not strain your eyes by looking at mobile phones, laptops or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience blurred vision for a prolonged period.
Warning & Precautions

Pregnancy
FLOXITRU P EYE DROPS is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before using it.

Breastfeeding
FLOXITRU P EYE DROPS is not recommended for use in breastfeeding women unless considered necessary by the physician. Therefore, consult your doctor before using it.

Driving and Using Machines
Do not drive or operate any heavy tools or machinery if you experience blurred vision or light-headedness after using FLOXITRU P EYE DROPS.

Kidney
FLOXITRU P EYE DROPS can be used in patients with kidney problems. However, consult your doctor before using it.

Liver
FLOXITRU P EYE DROPS can be used in patients with liver problems. However, consult your doctor before using it.

Allergy
Do not use FLOXITRU P EYE DROPS if you are allergic to Prednisolone, Moxifloxacin or to any other quinolone antibiotics (such as ciprofloxacin).
Others
FLOXITRU P EYE DROPS is not recommended for use if you:
- have severe viral or fungal eye infections
- previously had herpes simplex (a viral infection)
- have an eye infection that produces sticky pus
- have ulcers in the eyes
- have hole or ulceration in the outer layer of the eye (cornea)
Before using FLOXITRU P EYE DROPS inform your doctor if you:
- wear soft contact lenses
- have glaucoma
- have used any other steroid eye medication
Use in Pediatrics:
FLOXITRU P EYE DROPS is not recommended for use in children and adolescents (aged below 18 years) unless prescribed by a physician. Therefore, consult your doctor before administration.
Use in Geriatrics:
FLOXITRU P EYE DROPS should be used with caution in elderly patients. Therefore, consult your doctor before taking it.
Interactions
A. Drug - Drug interactions:
Before using FLOXITRU P EYE DROPS, inform your doctor if you are taking any of the following medicines such as:
- medicines used to manage HIV infections such as ritonavir, cobicistat
- medicines used to manage glaucoma (such as timolol, pindolol, acetazolamide, brinzolamide)
Overdosage:
If you or anyone else accidentally used excessive amount of this medicine, rinse your eyes or ears with warm water. If still irritation persists, consult your doctor for advice. If you or anyone else accidentally swallowed this medicine, consult your doctor immediately.
Synopsis
Drug | : | Prednisolone, Moxifloxacin |
Pharmacological Category | : | Topical Corticosteroids, Fluroquinolones |
Therapeutic Indication | : | Eye inflammation and infection |
Dosage Forms | : | Eye drops |
More Information
- Keep FLOXITRU P EYE DROPS out of reach of children
- Store FLOXITRU P EYE DROPS at room temperature
- Do not use this medicine after 4 weeks of its opening, even if it contains some left-over medicine
FAQs About FLOXITRU P EYE DROPS
Q: Can the use of FLOXITRU P EYE DROPS cause blurred vision?
A: Yes. FLOXITRU P EYE DROPS may cause blurred vision after application in some individuals, although not everybody gets them. If your vision becomes blur, close your eyes for some time and rest. Do not strain your eyes by looking at mobile phones, laptops or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience blurred vision for a prolonged period.
Q: Can I use other eye medicines while using FLOXITRU P EYE DROPS?
A: Avoid concomittant use of any eye medicines while using FLOXITRU P EYE DROPS without consulting your doctor.
Q: How to use FLOXITRU P EYE DROPS?
A: Use FLOXITRU P EYE DROPS as advised by your physician. It is for ophthalmic use only. Instil few drops of this medicine into the affected eyes. Wash your hands before and after application.
Q: What is the use of FLOXITRU P EYE DROPS?
A: FLOXITRU P EYE DROPS is a prescription medicine used to manage inflammation and/or infection in the eyes.
Q: How long does it take for FLOXITRU P EYE DROPS to work?
A: It may take around 10-15 minutes for FLOXITRU P EYE DROPS to start showing its effects. However, this period may vary from person-to-person depending upon the dose that is administered.
Q: What are the side effects of FLOXITRU P EYE DROPS?
A: The most common side effects of using FLOXITRU P EYE DROPS are mild eye irritation or burning sensation, blurred vision, increased eye pressure, headache and taste changes. Consult your doctor if any of these side effect worsens.
Q: Can I use FLOXITRU P EYE DROPS while wearing contact lenses?
A: If you wear soft contact lenses, remove the lens before applying FLOXITRU P EYE DROPS and wait for at least 15 minutes before reinsertion.
Q: Can I use FLOXITRU P EYE DROPS without consulting my doctor?
A: No. FLOXITRU P EYE DROPS is a prescription medicine which should be used only if prescribed by the physician. It is because, FLOXITRU P EYE DROPS contains a steroid medicine and a powerful antibiotic, which may cause harmful side effects when used without proper medical supervision. Therefore, consult your doctor for advice.
Q: Can I drive or ride a bike after using FLOXITRU P EYE DROPS?
A: Do not drive if you experience blurred vision after using FLOXITRU P EYE DROPS.
Q: What if I miss a dose of FLOXITRU P EYE DROPS?
A: If you missed a dose of FLOXITRU P EYE DROPS, apply it as soon as you remember. However, if it is time for next dose, skip the missed dose and use the regular dose. Do not use a double dose of FLOXITRU P EYE DROPS to compensate the missed dose.
Q: How FLOXITRU P EYE DROPS works?
A: FLOXITRU P EYE DROPS blocks the release of certain chemicals in the body (such as prostaglandins) that causes eye pain, inflammation and swelling. It also kills the susceptible bacteria that causes eye infection. Collectively, this medicine reduces inflammation and infection of the eyes.
Q: Can I stop using FLOXITRU P EYE DROPS once my symptoms subside?
A: No. Do not stop using this medicine without consulting your doctor as it may make your symptoms to re-appear. Therefore, use this medicine consistently for the duration instructed by your doctor to achieve better results.
References
1. KD. Tripathi. Sulfonamides, Cotrimoxazole and Quinolones. Corticosteroids. Hormones and Related Drugs. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 288 & 714.
2. Darlene Miller. Review of moxifloxacin hydrochloride ophthalmic solution in the treatment of bacterial eye infections. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. March 2008. [Accessed on 18th January 2023]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698721/
3. Allergan Pharmaceuticals Ireland. PRED FORTE 1% w/v Eye Drops, Suspension Prednisolone acetate. Electronics Medicines Compendium. [Revised in February 2022]. [Accessed on 18th January 2023]. https://www.medicines.org.uk/emc/files/pil.1354.pdf
4. RPH Pharmaceuticals AB. Electronics Medicines Compendium. [Revised in June 2018]. [Accessed on 18th January 2023]. https://www.medicines.org.uk/emc/files/pil.9148.pdf
5. Novartis Ireland Limited. MOXIVIG* 0.5% w/v eye drops, solution Moxifloxacin hydrochloride. Electronics Medicines Compendium. [Revised in October 2021]. [Accessed on 18th January 2023]. https://www.medicines.org.uk/emc/files/pil.5721.pdf
6. Central Drugs Standard Control Organization. Moxifloxacin HCl (5mg) + Prednisolone Acetate (10mg)per ml. (eye drops). October 2007. [Accessed on 18th January 2023]. https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadApprovalNewDrugs/dciApprovedfdc.pdf
7. Sunways India Pvt Ltd. OCCOMOX – P. Moxifloxacin 0.5% and Prednisolone 1% Eye Drops. [Accessed on 18th January 2023]. http://www.sunways.com/Products/SunwaysProducts/Occumox-P.html