Flodart Plus Capsule 10'S

Introduction About FLODART PLUS CAPSULE

FLODART PLUS CAPSULE is a combination of Dutasteride and Tamsulosin which belongs to the group of medicines called 5-Alpha reductase inhibitors and Alpha-blockers respectively. It is used to manage signs and symptoms of Benign Prostatic Hyperplasia (BPH) in men.

During this therapy, your doctor will regularly monitor your serum prostate-specific antigen (PSA) levels to detect the incidence of prostate cancer.

Before taking FLODART PLUS CAPSULE inform your doctor if you have any liver or kidney problems. Both pregnant women and children should avoid handling the leaking medicine, because this medicine has a high potential to get absorbed through your skin and can affect the normal development of a male baby (especially during the first 16 weeks of pregnancy).

Usage of condom during sexual intercourse is recommended among fertile men to avoid conception. It is not recommended for use in children and adolescents under 18 years of age. and should be used with caution in elderly patients above 65 years of age.

Common side effects of taking FLODART PLUS CAPSULE are dizziness, enlargement of breast in men and decreased sex drive. Consult your doctor if any of the side effects bothers you.

Key Composition

• Dutasteride
• Tamsulosin

Uses Of FLODART PLUS CAPSULE

• Manages signs and symptoms of benign prostatic hyperplasia (BPH) in men

Benefits of FLODART PLUS CAPSULE

• Helps manage symptoms of benign prostatic hyperplasia (BPH) such as difficulty in urination, frequent urges to urinate, and incomplete bladder emptying.
• Combines two active ingredients (Dutasteride and Tamsulosin) that work synergistically: Dutasteride reduces the size of the enlarged prostate by inhibiting hormones responsible for growth, while Tamsulosin relaxes the muscles of the prostate and bladder to improve urine flow.
• Supports reduction in urinary frequency, urgency, and nighttime urination, enhancing overall comfort.
• May lower the risk of urinary retention and decrease the likelihood of needing surgical intervention for BPH.
• Contributes to improved quality of life by easing urinary symptoms related to prostate enlargement.
• Convenient once-daily oral capsule that can be integrated into routine healthcare practices as advised by doctors.

How FLODART PLUS CAPSULE Works

• Dutasteride: It inhibits the conversion of testosterone to dihydrotestosterone (DHT), a hormone responsible for prostate gland enlargement. By lowering DHT levels, Dutasteride helps reduce the size of the enlarged prostate over time.
• Tamsulosin: This is an alpha-1 adrenergic blocker that relaxes the smooth muscles in the prostate and bladder neck, allowing easier urine flow and reducing urinary symptoms such as difficulty, urgency, or weak stream.

The combined effect of these two components helps alleviate symptoms associated with benign prostatic hyperplasia (BPH), such as frequent urination and incomplete bladder emptying, while reducing the risk of urinary retention. This dual-action approach improves urinary comfort and overall quality of life for patients with prostate enlargement.

How to use FLODART PLUS CAPSULE

Recommended Dosage and Administration

• Take one capsule once daily, preferably at the same time each day.
• Can be taken with or without food.
• Swallow the capsule whole with a full glass of water; do not crush, chew, or open.
• Follow your physician’s prescribed dosage based on individual health conditions.

How to Take FLODART PLUS CAPSULE

• Take consistently every day to maintain steady medication levels.
• If prescribed, take around 30 minutes after a meal to minimize stomach discomfort.
• Avoid missing doses to ensure best results.

Important Administration Guidelines

• Inform your doctor about all medications and supplements you are taking to prevent interactions.
• Be cautious if you experience dizziness or drowsiness; avoid driving or operating machinery if affected.
• Consult your doctor if you have liver, kidney, or heart conditions prior to starting.
• Use condom protection during sexual activity if your partner is or may be pregnant, due to potential effects on fetal development.
• Do not abruptly discontinue without medical guidance.

Consulting for Personalized Dosage

• Dosage and duration depend on factors like age, weight, and medical history.
• Regular follow-ups with the healthcare provider to adjust dosage as needed.
• Do not self-adjust or stop medication without consulting your doctor.

What if I forgot to take FLODART PLUS CAPSULE

• Take the missed dose as soon as you remember unless it’s close to the time for your next dose.
• If near the next dose time, skip the missed dose—do not double up on doses.
• Maintain the regular dosing schedule

Overdose

If you or anyone else accidentally take too much of FLODART PLUS CAPSULE, consult your doctor immediately. Overdosage may cause acute hypotension, nausea and vomiting.

Side Effects Of FLODART PLUS CAPSULE

Common

• sexual impotence (unable to achieve or maintain an erection)
• decreased sex drive
• difficulty in ejaculation
• gynecomastia (breast enlargement or tenderness)
• dizziness

When to consult a doctor?

• signs of allergic reaction (such as skin rash, itching, hives, and swelling of face, eyelids, lips, arms or legs)
• stevens-johnson syndrome (a severe widespread rash with blisters and peeling skin, particularly around the mouth, nose, eyes and genitals)

How To Manage Side Effects

Constipation

• Take fiber rich foods in your diet such as fresh fruits, vegetables, whole grain cereals and drink plenty of fluids.
• Exercise more regularly and stay active.

Dizziness Or Drowsiness

• Try to rest and relax. Get enough sleep.
• Avoid driving or operating any machines while you are feeling dizzy.
• Avoid consumption of alcohol as it can aggravate your dizziness.
• If the symptom persists for a longer time, contact your doctor for advice.

Nausea And Vomiting

• Take this medicine with or just after a meal or snack and stick to simple meals and do not eat oil rich or spicy foods.

Warning & Precautions

Pregnancy

Contraindicated

FLODART PLUS CAPSULE is intended for use only in men. Pregnant women should not come in contact with FLODART PLUS CAPSULE as it may cause potential abnormalities in male foetus.   

Breastfeeding

Contraindicated

FLODART PLUS CAPSULE is intended for use only in men and therefore should not be used in breastfeeding women.     

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you experience dizziness while taking FLODART PLUS CAPSULE

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking this medicine because it may cause excessive drowsiness. Consult your doctor before taking FLODART PLUS CAPSULE

Kidney

Use with Caution

FLODART PLUS CAPSULE should be used with caution if you have severe kidney disease. Consult your doctor for advice before taking it.

Liver

Consult your doctor

FLODART PLUS CAPSULE is not recommended for use in patients having severe liver disease and it should be used with caution in patients with liver problems. Consult your doctor for advice before taking it.

Allergy

Contraindicated

Do not take FLODART PLUS CAPSULE if you are allergic to Tamsulosin or Dutasteride and other 5-alpha reductase inhibitors such as finasteride and soya or peanut.

Heart Disease

Contraindicated

FLODART PLUS CAPSULE is not recommended for use in patients with low blood pressure (which causes dizziness, lightheadedness or fainting (orthostatic hypotension)). Consult your doctor for advice before taking it

Use In Pediatrics

Contraindicated

FLODART PLUS CAPSULE is not recommended for use in children or adolescents less than 18 years of age. Consult your child’s doctor for advice.

Use In Geriatrics

Use with Caution

FLODART PLUS CAPSULE should be used with caution in elderly patients above 65 years of age. Consult with your doctor for advice before taking FLODART PLUS CAPSULE.

Other Warnings for FLODART PLUS CAPSULE

Before taking FLODART PLUS CAPSULE, inform your doctor if you have:

• an upcoming cataract surgery
• blood test for PSA (Prostate Specific Antigen)

Who should not take [GBNKEYWORD

FLODART PLUS CAPSULE is not recommended for you, if you:

• are a woman (because this medicine is for men only)

Diet and Lifestyle Advice

• Maintain a Balanced Diet
  Eat a variety of fruits, vegetables, whole grains, and lean proteins to support overall health and potentially reduce BPH symptoms.
• Stay Hydrated
  Drink adequate fluids throughout the day, but limit intake of fluids a few hours before bedtime to reduce nighttime urination.
• Limit Caffeine and Alcohol
  Reduce consumption of caffeine and alcohol as these can irritate the bladder and worsen urinary symptoms.
• Manage Salt Intake
  Excessive salt can lead to fluid retention and swelling; moderate salt intake may help reduce related symptoms.
• Regular Physical Activity
  Engage in moderate exercise like walking or swimming to improve urinary function and overall wellbeing.
• Maintain a Healthy Weight
  Weight management can help reduce pressure on the bladder and improve symptoms.
• Avoid Medications That Can Worsen Symptoms
  Some over-the-counter cold, allergy, or sinus medications may increase urinary retention; consult a doctor before use.
• Practice Timed Voiding
  Establish a regular schedule for urination to train bladder and reduce urgency episodes.
• Avoid Holding Urine
  Urinate when the need arises to avoid bladder overdistension and further symptoms.
• Follow Doctor’s Instructions on Medication and Lifestyle
  Always take FLODART PLUS CAPSULE as prescribed and discuss any lifestyle changes with your healthcare provider.

Drug - Drug interaction

• Avoid using with certain medicines such as:
  • Boceprevir, Mavorixafor (not recommended together; doctor may decide alternative)
  • Alfuzosin, Prazosin, Doxazosin (other alpha-blockers; overlapping effects on blood pressure)
  • Carbamazepine, Clarithromycin, Ritonavir, Ketoconazole (may affect metabolism or increase side effect risks)
  • Beta-blockers like Atenolol, Metoprolol, Propranolol (may increase risk of low blood pressure or dizziness)
• Caution advised when combining with:
  • Other blood pressure lowering drugs (may cause excessive hypotension)
  • Medicines affecting liver enzymes (can change drug levels and effects)
  • Alcohol consumption may increase drowsiness and dizziness risks during use.
• Medical conditions to disclose to the doctor:
  • Liver or kidney disease (may affect how the medicine is processed)
  • Low blood pressure or history of dizziness/fainting
  • Glaucoma or eye surgery history (may worsen symptoms)

Synopsis

More Information

Day-in-the-Life Examples Using FLODART PLUS CAPSULE

Morning Routine

Mr. Sharma starts his day by taking his FLODART PLUS CAPSULE with a glass of water after breakfast. He appreciates the simple routine and schedules it alongside his daily vitamins. Throughout the morning, he notices comfort in his usual activities without frequent urge interruptions.

Workday Experience

During his busy office day, Mr. Sharma follows tips like timed bathroom breaks and staying hydrated without over-consuming fluids, which helps manage his urinary symptoms comfortably. He uses a phone alarm as a reminder for taking his medication every day at the same time.

Evening Wind-down

In the evening, Mr. Sharma avoids caffeine and limits fluid intake a few hours before bedtime. This helps reduce nighttime bathroom trips, letting him rest better and wake up refreshed.

Weekend Activity

On weekends, Mr. Sharma stays active with light exercises and a healthy diet, both advised by his healthcare provider to complement the capsule’s effects. He keeps a pillbox organizer handy for easy medication management even when out and about.

Traveling Comfort

While traveling, Mr. Sharma packs his medication securely, sets up alarms to maintain his dosing schedule, and follows storage advice to keep the capsules effective. His preparation ensures a smooth routine despite changes in environment.

Did you know

• Prostate enlargement, also known as benign prostatic hyperplasia (BPH), is a common condition affecting many men over 50, often causing urinary discomfort.
• Regular medication adherence and lifestyle changes can help support urinary comfort and overall prostate health.
• Some lifestyle factors such as reducing caffeine and alcohol intake can positively influence urinary habits when managing prostate symptoms.
• FLODART PLUS CAPSULE should only be used under medical supervision with regular check-ups to monitor progress and safety.

FAQs About FLODART PLUS CAPSULE

References

1. KD. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page – 303.

2. KD. Tripathi. Antiadrenergic Drugs (Adrenergic Receptor Antagonists) and Drugs for Glaucoma. Essentials of medical pharmacology. Seventh edition. 2013. Page – 142.

3. Peter J. Snyder. Androgens. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 1205.

4. GlaxoSmithKline. Benign Prostatic Hyperplasia Trial With Dutasteride And Tamsulosin Combination Treatment.  NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in February 2017] [Accessed on 3rd September 2025] 

5. Konstantinos Dimitropoulos and Stavros Gravas. Fixed-dose combination therapy with dutasteride and tamsulosin in the management of benign prostatic hyperplasia. NCBI; PMC US National Library of Medicine, National Institute of Health. February 2016. [Accessed on 3rd September 2025] 

6. J Miller and TH Tarter. Combination therapy with dutasteride and tamsulosin for the treatment of symptomatic enlarged prostate. NCBI; PMC US National Library of Medicine, National Institute of Health. June 2009. [Accessed on 3rd September 2025] 

7. Sibylle Marihart, Mike Harik and Bob Djavan. Dutasteride: A Review of Current Data on a Novel Dual Inhibitor of 5α Reductase. NCBI; PMC US National Library of Medicine, National Institute of Health. 2005. [Accessed on 3rd September 2025] 

8. Glenmark Pharmaceuticals Europe Limited. Laboratorios Leon Farma, SA. Electronic Medicines Compendium (EMC). [Revised in January 2020] [Accessed on 3rd September 2025] 

9. Dr. Reddy’s Laboratories (UK) Ltd, Laboratorios Leon Farma, SA. Electronic Medicines Compendium (EMC). [Revised in January 2020] [Accessed on 3rd September 2025] 

10. Cipla Ltd. Urimax D Tablets (Tamsulosin hydrochloride + Dutasteride). Ciplamed. [Revised in December 2013]. [Accessed on 3rd September 2025] 

Useful Diagnostic Tests

• Prostate-specific antigen (PSA) test

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed For Accuracy By Dr. Pushpraj Singh - MBBS

Last updated on 04 Sep 2025 | 12:38 PM(IST)