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FIASP FLEXTOUCH 100iu Pen 3ml

Diabetes
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    Introduction About FIASP FLEXTOUCH 100IU PEN

    FIASP FLEXTOUCH 100IU PEN contains Insulin Aspart, which belongs to the group of medicines called Antidiabetic agents. It is used to manage diabetes mellitus (both type I and type II).

    Diabetes mellitus is a chronic disease characterized by abnormally high levels of glucose in the blood. It is caused either by inadequate production of a hormone called insulin (produced by the pancreas to metabolize glucose) in the body or by inadequate sensitivity of body cells to the actions of insulin.

    FIASP FLEXTOUCH 100IU PEN is a fast-acting medicine that begins to lower blood sugar levels within 10–20 minutes after administration, and its effects may last up to 3–4 hours. FIASP FLEXTOUCH 100IU PEN is suitable for use both in adults and in children (aged 1 year or older).

    Talk to your doctor before starting therapy with FIASP FLEXTOUCH 100IU PEN if you have any liver, kidney, or heart problems. You must also inform your doctor if you have any hormonal problems, have made sudden changes to your diet, or are performing intense exercise as a precaution.

    Do not use this medicine if you have hypoglycemia (low blood sugar levels). Consult your doctor before using this medicine if you are pregnant or breastfeeding.

    The most common side effects of injecting FIASP FLEXTOUCH 100IU PEN are low blood sugar levels, pain, redness, itching, swelling or thickening at the injection site, lump formation under the skin, and swelling of body parts. Consult your doctor if any of these side effects trouble you.

    Uses Of FIASP FLEXTOUCH 100IU PEN

    • To manage diabetes mellitus (both type I and type II)

    How FIASP FLEXTOUCH 100IU PEN Works

    FIASP FLEXTOUCH 100IU PEN helps your body make use of the circulating blood glucose. It helps in the transport of glucose from the blood into the muscles and fat tissues. It also stops the production of glucose in the liver. As a result, it controls blood sugar levels and improves sugar control in patients with diabetes mellitus.

    How to use FIASP FLEXTOUCH 100IU PEN

    Always inject this medicine into your thighs, buttocks, upper arm, or abdomen (i.e., subcutaneously). Do not administer this medicine into the vein or muscle directly. It should be administered at least 10 minutes before meals. Eat a meal or snack containing carbohydrates within 20 minutes of the injection to avoid low blood sugar.

    Before administration, roll the vial or cartridge between your hands until the liquid becomes uniformly white and cloudy. While injecting, keep the needle under the skin for at least 6 seconds to make sure that the entire dose is injected.

    Prior to administration, visualize the cartridge or vial for any visible particulate matter and discoloration. Discard the needle and syringe after use, and do not share your needles with others to avoid the risk of infection transmission.

    Avoid repeatedly injecting the medicine at the same site to manage skin damage. Instead, rotate the injection site. Make sure to consult your doctor before changing the injection site as a precaution.

    Consult your doctor before mixing FIASP FLEXTOUCH 100IU PEN with other insulins. Do not stop therapy with FIASP FLEXTOUCH 100IU PEN without consulting your doctor. Your doctor will determine the correct dose and frequency of administration depending on your age, body weight, and health condition.

    Side Effects Of FIASP FLEXTOUCH 100IU PEN

    Common

    • Injection site reactions (such as pain, redness, itching, or swelling)
    • Lipodystrophy (shrinkage of fat tissues beneath the skin)
    • Lumps under the skin
    • Weight gain, swelling of body parts
    • Hypoglycemia (low blood sugar levels)

    Uncommon

    • Diabetic retinopathy (eye diseases due to diabetes)
    • Swelling around the ankles and other joints

    Rare

    • Problems with vision
    • Painful neuropathy (pain caused by nerve damage)

    Consult your doctor immediately if you experience any of the following side effects:

    • Allergic reaction (generalized skin rash with itching, sweating, and swelling of layers under the skin, difficulties in breathing, palpitation, vomiting, stomach upset, reduction in blood pressure, and fainting or loss of consciousness)
    • Signs of severe hypoglycemia (such as cold sweats, cool pale skin, headache, rapid heartbeat, nausea, increased hunger, temporary vision changes, drowsiness, tiredness and weakness, nervousness or tremor, anxiety, confusion, and difficulty concentrating)

    How To Manage Side Effects

    Hypoglycemia

    Have foods rich in sugars, such as fruit juices, glucose drinks, candies, honey, or biscuits. Check your blood sugar after 10 minutes. If you have not reached your optimum level, take another sugary snack or drink and check your blood sugar again. Consult your doctor if there is no improvement in your condition.

    Injection Site Reactions

    Place an ice pack on the injected site. Do not move the affected area frequently. If the symptom worsens, consult your doctor. Do not inject this medicine at the same site. Always rotate injection sites within the same region from one injection to the next to reduce skin damage.

    Warning & Precautions

    Pregnancy

    Monitoring required

    FIASP FLEXTOUCH 100IU PEN can be used during pregnancy if prescribed by the physician. Therefore, consult your doctor before administration.

    Breastfeeding

    Safe

    FIASP FLEXTOUCH 100IU PEN is considered safe for use during breastfeeding. However, consult your doctor before administration.

    Driving and Using Machines

    Use with Caution

    Do not drive or operate any heavy tools or machines if your abilities are affected by FIASP FLEXTOUCH 100IU PEN.

    Alcohol

    Consult your doctor

    Avoid consuming alcohol while undergoing therapy with this medicine, as it could aggravate your existing disease condition.

    Kidney

    Use with Caution

    FIASP FLEXTOUCH 100IU PEN should be used with caution in patients with kidney problems. Therefore, consult your doctor before administration.

    Liver

    Use with Caution

    FIASP FLEXTOUCH 100IU PEN should be used with caution in patients with liver problems. Therefore, consult your doctor before administration.

    Allergy

    Contraindicated

    Talk to your doctor before receiving FIASP FLEXTOUCH 100IU PEN if you are allergic to insulin aspart or to any other insulin types (Ex. Lente, ultra-Lente).

    Heart Disease

    Use with Caution

    FIASP FLEXTOUCH 100IU PEN should be used with caution in patients with heart problems. Therefore, consult your doctor before administration.

    Use In Pediatrics

    Monitoring required

    FIASP FLEXTOUCH 100IU PEN can be used in children (aged 1 year or older) and in adolescents (aged below 18 years) if prescribed by the physician. Therefore, consult your doctor before administration.

    Use In Geriatrics

    Use with Caution

    FIASP FLEXTOUCH 100IU PEN should be used with caution in elderly patients (aged 65 years or older). Therefore, consult your doctor before administration. Proper dose adjustments and careful monitoring of blood glucose levels and kidney functions are required in such patients.

    Others

    FIASP FLEXTOUCH 100IU PEN is not recommended for use if you:

    • Have or are at risk of developing hypoglycemia (low blood sugar levels)

    Before receiving FIASP FLEXTOUCH 100IU PEN, inform your doctor if you:

    • Have problems in the adrenal, pituitary, or thyroid gland
    • Have recently changed your diet plan and lifestyle
    • Are exercising more than usual
    • Recently became ill or had infections
    • Are planning to go abroad (as mealtime and injection timings may change)

    Interactions

    A. Drug-Drug interactions:

    Before receiving FIASP FLEXTOUCH 100IU PEN, inform your doctor if you are taking any of the following medicines:

    • Other medicines used to manage diabetes include sulfonylureas (Ex. tolbutamide, glibenclamide, and glipizide), biguanides (Ex. metformin and phenformin), thiazolidinediones (Ex. pioglitazone), DPP-4 inhibitors (Ex. sitagliptin and vildagliptin), and SGLT-2 inhibitors (Ex. remogliflozin)
    • Medicines used to manage depression, such as monoamine oxidase inhibitors (Ex. rasagiline, selegiline, and phenelzine),
    • Medicines used to manage high blood pressure and other heart problems, such as beta-blockers (Ex. propranolol, atenolol, and nebivolol) or ACE inhibitors (Ex. captopril, enalapril, and lisinopril),
    • Salicylates (used to relieve pain or fever) Ex. aspirin
    • Anabolic steroids (used to build muscle and improve athlete performance) Ex. testosterone, nandrolone, and oxandrolone
    • Sulphonamide antibiotics (used to manage bacterial infections) Ex. sulfasalazine, sulfadiazine, sulfamethoxazole
    • Oral contraceptives (birth control pills), Ex. mifepristone,
    • Thiazide diuretics (used to increase urine output and reduce blood pressure) Ex. chlorothiazide, hydrochlorothiazide
    • Glucocorticoids (used to manage inflammation) Ex. cortisone, betamethasone, beclomethasone, dexamethasone, budesonide, and prednisone
    • Thyroid hormone (used to manage thyroid disorders) Ex. thyroxine, triiodothyronine
    • Sympathomimetic agents (used to manage asthma or other circulatory disorders) Ex. ephedrine, adrenaline, salbutamol, or terbutaline
    • Growth hormone (a hormone used to increase skeletal and somatic growth in the body)
    • Danazol (a medicine used to manage endometriosis)
    • Octreotide (used to manage diarrhea)
    • Lanreotide (a medicine used to manage abnormal body growth)

    B. Drug-Food interaction:

    FIASP FLEXTOUCH 100IU PEN should be administered at least 10 minutes before a meal.

    Overdosage:

    If you or anyone else received too much of this medicine, contact your doctor immediately or go to a hospital right away, as it may cause severe hypoglycemia. Symptoms of hypoglycemia might include fainting, feeling unwell, sweating, vomiting, difficulty breathing, a fast heartbeat, and dizziness.

    Synopsis

    Drug :   Insulin Aspart
    Pharmacological Category :   Antidiabetic agents
    Therapeutic Indication :   Diabetes mellitus        
    Dosage Forms :   Injection, Cartridge, Pen, Penfill

    More Information

    • Keep out of reach of children
    • Store FIASP FLEXTOUCH 100IU PEN in the refrigerator at 2-8°C. Do not freeze

    FAQs About FIASP FLEXTOUCH 100IU PEN

    Q: Should FIASP FLEXTOUCH 100IU PEN be refrigerated?

    A: Yes. An unopened pack must be stored in the refrigerator (2°C–8°C). During use or while carrying it as a spare, keep it at room temperature to ensure uniform resuspension.

    Q: Can FIASP FLEXTOUCH 100IU PEN be mixed with other insulins?

    A: No. FIASP FLEXTOUCH 100IU PEN is already a pre-mixed combination of regular insulin and isophane insulin and therefore should not be mixed with other insulin. For more information regarding the direction of use, contact your doctor.

    Q: Is FIASP FLEXTOUCH 100IU PEN safe during pregnancy?

    A: Yes. FIASP FLEXTOUCH 100IU PEN can be used during pregnancy if prescribed by the physician. Therefore, consult your doctor before administration.

    Q: How long does it take for FIASP FLEXTOUCH 100IU PEN to start working?

    A: FIASP FLEXTOUCH 100IU PEN is a fast-acting medicine where it begins to lower blood sugar levels about 10 minutes post administration and its effect would last for about 3–5 hours.

    Q: Can FIASP FLEXTOUCH 100IU PEN be given intravenously?

    A: No. FIASP FLEXTOUCH 100IU PEN is meant for subcutaneous use only (i.e., thighs, buttocks, abdomen, or upper arms). It should not be directly injected into the vein or muscle, as it may cause severe hypoglycemia.

    Q: What is the best area for injecting FIASP FLEXTOUCH 100IU PEN? Should I inject it at the same site every day?

    A: The best place for injecting this medicine is in front of your thighs, buttocks, abdomen, or upper arms. The insulin would work more quickly if it were injected into the waist (abdomen). Do not repeatedly inject the medicine at the same site. Instead, rotate the injection sites within the same area to avoid the risk of developing lumps or skin pitting.

    Q: What are the most common side effects of receiving FIASP FLEXTOUCH 100IU PEN?

    A: The most common side effects of receiving FIASP FLEXTOUCH 100IU PEN are low blood sugar levels, pain, redness, itching, swelling, or thickening at the injection site, lump formation under the skin, and swelling of body parts. Consult your doctor if any of these side effects trouble you.

    Q: Can I stop therapy with FIASP FLEXTOUCH 100IU PEN without consulting your doctor?

    A: No. You should not stop therapy with FIASP FLEXTOUCH 100IU PEN without consulting your doctor because it may lead to the reversal of symptoms. If you feel better after using FIASP FLEXTOUCH 100IU PEN, consult your doctor for advice.

    Q: Will injecting a higher dose of FIASP FLEXTOUCH 100IU PEN be more effective?

    A: No, injecting a higher dose of FIASP FLEXTOUCH 100IU PEN will not be effective; rather, it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.

    Q: Can I take medication for high blood pressure along with FIASP FLEXTOUCH 100IU PEN?

    A: It is not advisable to take medicines to control blood pressure while taking FIASP FLEXTOUCH 100IU PEN without consulting your doctor. Therefore, consult your doctor before taking any antihypertensive medications along with FIASP FLEXTOUCH 100IU PEN, as they have known interactions with FIASP FLEXTOUCH 100IU PEN.

    References

    1. KD. Tripathi. Insulin, Oral Hypoglycemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 265.

    2. Rochelle Rubin; Niloufar R. Khanna; Lindsey A. McIver. Aspart Insulin. StatPearls. NIH. National Library of Medicine. National Center for Biotechnology. PMC. PubMed Central. November 2022. [Accessed on 18th January 2024] https://www.ncbi.nlm.nih.gov/books/NBK500030/#:~:text=and%20adverse%20effects.-,Insulin%20aspart%20is%20a%20rapid%2Dacting%2C%20human%20insulin%20analog%20that,not%20an%20FDA%2Dapproved%20indication

    3. Novo Nordisk A/S. Electronic Medicines Compendium. [Revised in August 2022]. [Accessed on 18th January 2024] https://www.medicines.org.uk/emc/files/pil.2447.pdf

    4. Novo Nordisk A/S. Electronic Medicines Compendium. [Revised in October 2022]. [Accessed on 18th January 2024] https://www.medicines.org.uk/emc/files/pil.7919.pdf

    Useful Diagnostic Tests

    • HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
    • Blood Glucose Fasting (FBS)
    • Random Blood Sugar (RBS)
    • Post Prandial Blood Sugar (PPBS)
    • Insulin-Fasting
    • Insulin Postprandial (PP)
    • Vital Diabetes Care
    • Extended Diabetes Care
    • Advance Diabetes Care
    • Comprehensive Diabetes Care

    Author Details

    Written By Dr. N. Sai Swaroop - Pharm.D
    Reviewed For Accuracy By Dr. Jaya Prabakaran - MBBS, MD (Diabetology and Family Medicine)
    Last updated on 24 Jan 2024 | 06:10 PM(IST)
    Lab updated