FEBREX 500mg(L)
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Introduction About FEBREX 500MG(L)
FEBREX 500MG(L) contains Paracetamol which belongs to the group of medicines called Analgesics and Antipyretics. It is used to provide relief from fever and mild to moderate body pains, headache, muscle pain, menstrual pain and signs of common cold and flu.
Before taking FEBREX 500MG(L), inform your doctor if you or your child have liver or kidney problems or any allergies. It should be used with caution in patients with liver problems due to alcohol to manage the risk of liver damage.
FEBREX 500MG(L) should be used with caution in pregnant women only if clearly advised by the doctor and can be used in breastfeeding women. FEBREX 500MG(L) is not recommended for use in children less than 10 years of age and should be used with caution in elderly patients.
Consult your doctor if you experience any side effects or unusual effects during management with FEBREX 500MG(L).
Uses Of FEBREX 500MG(L)
- relieves mild to moderate pain (such as headache, toothache, joint pain)
- lowers fever and relieves the symptoms of cold or flu
How FEBREX 500MG(L) Works
FEBREX 500MG(L) relieves pain by increasing the pain threshold by inhibiting certain enzymes (COX-1 and COX-2) involved in the synthesis of chemicals responsible for inducing pain (prostaglandins). It reduces fever by directly acting on heat-regulating centers in the brain, resulting in vessel relaxation, sweating and loss of body heat.
How to use FEBREX 500MG(L)
Take FEBREX 500MG(L) as advised by your physician. It can be taken with or without food.
For Tablet, Capsule: Swallow FEBREX 500MG(L) with a glass of water. Do not crush or chew the medicine.
For Dispersible Tablet: Disperse the medicine in the specified quantity of water as mentioned on the label. Consume the medicine immediately after reconstitution.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of the condition.
Side Effects Of FEBREX 500MG(L)
FEBREX 500MG(L) is generally well tolerated. However, consult your doctor if you experience any unusual reactions or allergies (such as swelling of the hands, feet, ankles, face, lips or throat which may cause trouble swallowing or breathing, an itchy, lumpy rash or nettle rash, runny nose)
Warning & Precautions
Pregnancy
Monitoring requiredFEBREX 500MG(L) should be used with caution in pregnant women only if considered clearly necessary. Your doctor may use the lowest possible dose to reduce the pain and fever only for a shorter duration in pregnant women. Consult your doctor before taking FEBREX 500MG(L).
Breastfeeding
Use with CautionFEBREX 500MG(L) should be used with caution in breastfeeding women. Consult your doctor before taking it.
Driving and Using Machines
Use with CautionFEBREX 500MG(L) has no influence on the ability to drive and operate machinery.
Alcohol
Consult your doctorFEBREX 500MG(L) should be used with caution in patients with chronic alcoholism. Consult your doctor before taking it.
Kidney
Use with CautionFEBREX 500MG(L) should be used with caution in patients with severe kidney problems. Consult your doctor before taking it.
Liver
Use with CautionFEBREX 500MG(L) should be used with caution in patients with severe liver problems or liver problems due to alcohol. Consult your doctor before taking it.
Allergy
ContraindicatedDo not take FEBREX 500MG(L) if you are allergic to Paracetamol or any other ingredients of this medicine.
Use In Pediatrics
Consult your doctorFEBREX 500MG(L) is not recommended for use in children less than 10 years of age. It can be used in children and adolescents aged above 10 and your child’s doctor may adjust the dose based on the child’s age and body weight. Consult your child’s doctor for advice.
Use In Geriatrics
Use with CautionFEBREX 500MG(L) should be used with caution in elderly patients. Consult your doctor before taking it.
Others
Before taking FEBREX 500MG(L), inform your doctor if you:
- have sepsis (circulation of bacteria and their toxins in the blood leading to organ damage)
- are malnourished
Interactions
A. Drug-Drug interactions:
Before taking FEBREX 500MG(L), inform your doctor if you are taking any of the following medicines:
- other medicines containing paracetamol
- medicines to manage nausea and vomiting (Ex. metoclopramide, domperidone)
- cholestyramine (used to control blood lipid levels)
- warfarin (used for managing blood clots)
- medicines used to manage bacterial infections (Ex. rifampicin, flucloxacillin, chloramphenicol)
Overdosage:
If you or anyone else accidentally takes too much of FEBREX 500MG(L), consult your doctor immediately or visit the nearby hospital, even if you feel well, as it can cause delayed, serious liver damage.
Synopsis
| Drug | : | Paracetamol |
| Pharmacological Category | : | Para aminophenol derivative |
| Therapeutic Indication | : | Pain, Fever |
| Dosage Forms | : | Tablet, Dispersible tablet, Drops, Syrup, Oral suspension, Liquid, Oral solution, Suppositories, Infusion, Injection |
More Information
Storage
- Keep FEBREX 500MG(L) out of reach of children
- Store below 25°C
FAQs About FEBREX 500MG(L)
Q: What is the use of FEBREX 500MG(L)?
A: FEBREX 500MG(L) is commonly used to relieve mild to moderate pain and reduce fever. It contains paracetamol (acetaminophen) and is often used for conditions like headaches, muscle aches, toothaches, associated with various illnesses.
Q: What happens if I take FEBREX 500MG(L)?
A: FEBREX 500MG(L) contains a medicine called paracetamol which is an analgesic and antipyretic agent. Following administration, it works by blocking the release of certain chemicals called prostaglandins in the body which is responsible for causing pain and inflammation. Paracetamol also manages the release of such chemicals in the hypothalamus of the brain which helps in controlling fever.
Q: Can I take two doses of FEBREX 500MG(L) in a day?
A: The dosage of FEBREX 500MG(L) is decided by your physician. However, studies have shown that taking paracetamol once in every 4-6 hours significantly reduced fever and body pains.
Q: Can we use FEBREX 500MG(L) for cold?
A: FEBREX 500MG(L) could be used in the management of sore throat and body pains that is associated with common cold. It contains a medicine called paracetamol which is commonly used to relieve mild to moderate pain, like headaches, muscle aches, toothaches, and fever associated with various illnesses.
Q. Can I take FEBREX 500MG(L) as often as required?
A: The dosage of FEBREX 500MG(L) and duration of the therapy would be decided by your doctor. It is usually not recommended to take more than 4 doses of FEBREX 500MG(L) in a day. Leave a time gap of 4-6 hours, between each dose.
Q: Is FEBREX 500MG(L) a strong medicine?
A: FEBREX 500MG(L) is relatively an effective medicine in controlling fever and body pain. It is typically used for mild to moderate pain relief and fever reduction. However, it should be used as directed, and exceeding the recommended dosage can lead to adverse effects.
Q: When would FEBREX 500MG(L) start working?
A: It takes around 30 minutes for you to feel better after taking FEBREX 500MG(L).
Q: Can I take FEBREX 500MG(L) and ibuprofen together?
A: It is generally advisable to avoid taking FEBREX 500MG(L) (paracetamol) and ibuprofen together unless recommended by a healthcare professional. Mixing these medications can increase the risk of side effects and potential harm to the liver and stomach.
Q: When should we discontinue the use of Paracetamol?
A: Discontinue the use of Paracetamol if you experience allergic reactions, severe skin reactions, liver problems, or if you consume alcohol regularly. Always consult a healthcare professional if you have concerns or experience adverse effects.
Q: Is FEBREX 500MG(L) an antibiotic?
A: No. FEBREX 500MG(L) is an analgesic and antipyretic medicine. It works by reducing fever and provides pain relief.
Q: What happens if I take more doses of FEBREX 500MG(L) than recommended to me?
A: Taking more than the recommended doses of FEBREX 500MG(L) may be harmful. Studies have shown that the overdosage of paracetamol may affect your liver and gastrointestinal tract. Symptoms of overdosage might include vomiting, loss of appetite, stomach pain, paleness and nausea.
Q: Can FEBREX 500MG(L) be used for a headache?
A: Yes. FEBREX 500MG(L) can relieve your headache. It can also symptomatically manage headaches, however, cannot manage the underlying cause. If you experience recurrent headaches, please consult your doctor. In such cases, avoid self-medication with over-the-counter pain killers.
Q: Can FEBREX 500MG(L) be used during pregnancy?
A: FEBREX 500MG(L) can be used during pregnancy, however not during the last trimester as it could delay the onset of pain sensation. If necessary, you should use the lowest possible dose that reduces your pain and/or your fever and use it for the shortest time possible.
Q: What happens if I take Dolo 650 without fever?
A: Dolo 650 tablet is generally used for managing pain and fever, It can be used without getting a fever in most cases, especially if you have headaches, toothaches, or period cramps.
References
1. Tilo Grosser, Emer Smyth and Garret A. FitzGerald. Anti-inflammatory, Antipyretic and Analgesic agents; Pharmacotherapy of gout. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page-693.
2. KD. Tripathi. NSAIDs and Antipyretic-Analgesics. Essentials of Medical Pharmacology. Seventh edition. 2013. Page-206.
3. Ulderico Freo, Chiara Ruocco, Alessandra Valerio, Irene Scagnol and Enzo Nisoli. Paracetamol: A Review of Guideline Recommendations. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. August 2021. [Accessed on 12th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347233/
4. Ohashi N and Kohno T. Analgesic Effect of Acetaminophen: A Review of Known and Novel Mechanisms of Action. Pharmacology. Frontiers. November 2020. [Accessed on 12th August 2022] https://www.frontiersin.org/articles/10.3389/fphar.2020.580289/full
5. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in April 2022] [Accessed on 12th August 2022] https://www.medicines.org.uk/emc/files/pil.1958.pdf
6. Zentiva Pharma UK Limited. Electronic Medicines Compendium (EMC). [Revised in May 2022] [Accessed on 12th August 2022] https://www.medicines.org.uk/emc/files/pil.4195.pdf
7. GlaxoSmithKline Asia Private Limited. Crocin 500 mg and Crocin 650 mg (Paracetamol). [Accessed on 12th August 2022] https://www.crocin.com/content/dam/cf-consumer-healthcare/panadol/en_in/adult/productshots/pdfs/Crocin-650-mg-Product-Info.pdf
Useful Diagnostic Tests
- Complete blood count
- Liver function test
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