Netmeds First Membership
Quick Links
Introduction About EVERTOP OINTMENT
EVERTOP OINTMENT is used to manage mild to moderate atopic dermatitis (AD), such as dry, itchy, swollen, and red skin. It contains Tofacitinib, which belongs to the group of medicines called Janus Kinase Inhibitors. It suppresses an overactive immune system by inhibiting certain enzymes called Janus kinases (JAKs). Thus, EVERTOP OINTMENT blocks the production of pro-inflammatory substances (including cytokines) that contribute to the development of inflammation and other symptoms of atopic dermatitis.
Apply EVERTOP OINTMENT to the affected area as directed by your doctor to get the most benefit. Prior to the initiation of this medicine, your doctor may order blood tests to understand and monitor your existing condition.
EVERTOP OINTMENT is not recommended for use in pregnant women and breastfeeding women. Consult your doctor before using it.
EVERTOP OINTMENT is not recommended for use if you have active tuberculosis (TB) or severe liver disease. Consult your doctor before using it.
EVERTOP OINTMENT should be used with caution in patients with a history of chronic lung disease or in those who develop interstitial lung disease due to the increased risk of infections. Consult your doctor before using it.
The safety and efficacy of EVERTOP OINTMENT in children are not established. Consult your child’s doctor for advice.
The most common side effects of using EVERTOP OINTMENT are application site eczema, application site itching, and fever. Consult your doctor if any of the side effects worsen.
Uses Of EVERTOP OINTMENT
It is used to:
- manage mild to moderate atopic dermatitis
How EVERTOP OINTMENT Works
EVERTOP OINTMENT suppresses an overactive immune system by inhibiting certain enzymes called Janus kinases (JAKs). Thus, EVERTOP OINTMENT blocks the production of pro-inflammatory substances (including cytokines) that contribute to the development of inflammation and other symptoms of atopic dermatitis.
How to use EVERTOP OINTMENT
Apply EVERTOP OINTMENT as advised by your doctor. It is for external use only. Apply EVERTOP OINTMENT as a thin layer to the affected area as directed by your doctor to get the most benefit. Your doctor will decide the correct dose and duration of EVERTOP OINTMENT for you depending upon your age, body weight, and disease condition.
Overdose
If you or anyone else accidentally swallows too much of EVERTOP OINTMENT, consult your doctor immediately or visit the nearby hospital.
Side Effects Of EVERTOP OINTMENT
Common side effects of EVERTOP OINTMENT:
- Application site eczema
- Application site itching
- Fever
Stop taking EVERTOP OINTMENT and contact your physician immediately if you experience any of the following side effects:
- Serious infection, an opportunistic infection, or sepsis
- Serious allergic reactions such as urticaria and angioedema
- Signs of myocardial infarction or stroke
How To Manage Side Effects
Skin rash Or Itching
Keep the affected area clean and dry and avoid scratching to prevent further irritation or infection. Apply calamine lotion to help reduce itching and inflammation. Applying cool compresses and wearing loose, breathable clothing can also provide relief. If the itching persists, consult your doctor.
Warning & Precautions
Pregnancy
ContraindicatedEVERTOP OINTMENT is not recommended for use by pregnant women. Women of childbearing potential should be advised to use effective contraception during management with EVERTOP OINTMENT and for at least 4 weeks after the last dose. Consult your doctor before using it.
Breastfeeding
ContraindicatedEVERTOP OINTMENT is not recommended for use by breastfeeding women. Consult your doctor before using it.
Driving and Using Machines
Use with CautionEVERTOP OINTMENT has no influence on the ability to drive or operate machinery.
Liver
ContraindicatedEVERTOP OINTMENT is not recommended for use if you have severe liver disease. Consult your doctor before using it.
Allergy
ContraindicatedDo not use EVERTOP OINTMENT if you are allergic to tofacitinib or any of the other ingredients in this medicine.
Lungs
Consult your doctorEVERTOP OINTMENT is not recommended for use if you have active tuberculosis (TB). It should be used with caution in patients with a history of chronic lung disease or in those who develop interstitial lung disease due to the increased risk of infections. Consult your doctor before using it.
Use In Pediatrics
Consult your doctorThe safety and efficacy of EVERTOP OINTMENT in children are not established. Consult your child’s doctor for advice.
Other Warnings for EVERTOP OINTMENT
Before using EVERTOP OINTMENT, inform your doctor if you:
- Have a chronic or recurrent infection
- Have been exposed to tuberculosis
- History of a serious or an opportunistic infection
- Have resided or travelled in areas of endemic tuberculosis or endemic mycoses
- Have underlying conditions that may predispose to infections
- Have a decrease in white blood cell count
- Have herpes zoster (due to virus reactivation)
- Have an increased risk of thrombosis (blood clots)
Who should not take EVERTOP OINTMENT
EVERTOP OINTMENT is not recommended for use if you:
- Have serious infections, such as sepsis, or opportunistic infections
- Have a low white blood cell count
- Have low levels of haemoglobin
Drug - Drug interaction
- Antifungals (Ex. ketoconazole, fluconazole)
- Anti-tubercular agent (Ex. rifampicin)
- Immunosuppressants (Ex. tacrolimus, ciclosporin)
- Live vaccines
Synopsis
|
Drug |
Tofacitinib |
|
Pharmacological Category |
Janus Kinase Inhibitors |
|
Therapeutic Indication |
Atopic dermatitis |
|
Dosage Forms |
Tablet, Capsule, Gel, and Ointment |
More Information
Storage
- Keep EVERTOP OINTMENT out of reach of children
- Store at room temperature not exceeding 30ºC. Do not freeze
References
1. Purohit VS, Ports WC, Wang C, Riley S. Systemic Tofacitinib Concentrations in Adult Patients With Atopic Dermatitis Treated With 2% Tofacitinib Ointment and Application to Pediatric Study Planning. NIH, National Library of Medicine. National Centre for Biotechnology Information. PubMed Central. [Revised in December 2018] [Accessed on 21st July 2026] 
2. MSN Laboratories Private Limited. Tofacitinib. [Revised in September 2023] [Accessed on 21st July 2026] 