EMPAONE 25 Tablet 10's
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Introduction About EMPAONE 25 TABLET
EMPAONE 25 TABLET contains Empagliflozin which belongs to the group of medicines called Anti-diabetic drugs. It is used to manage type 2 diabetes in adults, that cannot be controlled by diet and exercise alone. It can also help in reducing the risk of heart disease in patients with type 2 diabetes mellitus. Also, it is used in the management of heart failure in adult patients with weak pumping function.
Diabetes can be defined as inability of your body to produce and use enough insulin (a hormone made by pancreas), resulting in abnormal blood glucose levels. It can show symptoms like increased thirst, urination and hunger, blurry vision, numbness in hands or feet or tiredness. Heart failure occurs when the heart is weak and unable to pump enough blood to the lungs and the rest of the body, creating symptoms like breathlessness, tiredness and ankle swelling.
Appropriate diet and exercise can help your body use its blood sugar better. Follow any advice given by your doctor regarding foot care. Prior to the management, your doctor may want you to take several blood tests to understand your existing condition.
Before taking EMPAONE 25 TABLET, inform your doctor if you have any serious liver, kidney or heart problems or diabetes type 1. EMPAONE 25 TABLET is not recommended in pregnant or breastfeeding women, therefore consult your doctor before taking. EMPAONE 25 TABLET is not recommended for use in children and adolescents (below 18 years of age).
Due to limited therapeutic experience, elderly patients (above 75 years of age) should consult the doctor before taking EMPAONE 25 TABLET. The most common side effects of taking EMPAONE 25 TABLET are low blood sugar, genital infection, frequent urination, rash, itching, thirst, or constipation. Consult your doctor if any of the symptoms get worsen.
Uses Of EMPAONE 25 TABLET
It is used to:
- manage type 2 diabetes mellitus
- reduce the risk of heart disease in diabetic patients
- manage heart failure (with symptoms due to a weak pump function of the heart)
How EMPAONE 25 TABLET Works
EMPAONE 25 TABLET works by blocking a protein (SGLT2) in your kidneys. This results in removal of blood sugar (glucose) in your urine, thus lowering the amount of sugar in your blood. It also helps protect your heart from getting weaker and relieve your symptoms.
How to use EMPAONE 25 TABLET
Take EMPAONE 25 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Do not stop taking EMPAONE 25 TABLET unless your doctor advice you to stop.
Side Effects Of EMPAONE 25 TABLET
Common
- low blood sugar levels (shaking, sweating, feeling very anxious or confused, fast heartbeat, excessive hunger, headache)
- urinary tract infection (burning sensation when passing urine, cloudy-looking urine, pain in the pelvis or mid-back)
- dehydration (unusual thirst, light-headedness or dizziness upon standing, fainting or loss of consciousness)
- genital yeast infection (itching in vagina, burning sensation during intercourse, vaginal pain, redness, rash, swelling, white discharge)
- frequent urination
- itching, rash or red skin
- constipation
Uncommon
- hives
- stretching or pain when emptying the bladder
Rare
- fournier’s gangrene (a serious infection of the genitals or the area between the genitals and the anus)
Stop taking EMPAONE 25 TABLET and consult your doctor immediately if you experience any of the following side effects:
- severe allergic reaction (swelling of the face, lips, mouth, tongue, or throat that may cause difficulty in breathing or swallowing)
- diabetic ketoacidosis (rapid weight loss, nausea, stomach pain, too much thirst, breathlessness, confusion, tiredness, a sweet-smelling breath, a sweet or metallic taste in your mouth or a different odour to your urine or sweat)
How To Manage Side Effects
Constipation
Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise more regularly. Consult your doctor if the symptom does not improve.
Hypoglycemia
Have a fruit juice, glucose tablets or gel, soft drinks, honey, or sugary candy. Check your blood sugar after 10 minutes. If not gained optimum level, take another sugary snack or drink, and check the blood sugar again. If the symptom does not improve, contact your doctor.
Nausea And Vomiting
Take this medicine with, or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. Consult your doctor if the symptom does not improve.
Stomach Pain
Try to rest and relax. Eat and drink slowly or try to have smaller and more frequent meals. Keep a heat pad on your stomach. If the symptom does not improve, contact your doctor.
Warning & Precautions
Pregnancy
ContraindicatedEMPAONE 25 TABLET is generally not recommended for use in pregnant women. Consult your doctor before taking it.
Breastfeeding
ContraindicatedEMPAONE 25 TABLET is generally not recommended for use in breastfeeding women. It is not known if this medicine passes into human breast milk, so consult your doctor before taking it.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel dizzy after taking EMPAONE 25 TABLET.
Kidney
Use with CautionEMPAONE 25 TABLET should be taken with caution in patients with severe kidney disease and serious infection of the kidney. Consult your doctor before taking it.
Liver
Use with CautionEMPAONE 25 TABLET should be used with caution in patients with severe liver disease. Consult your doctor before taking it.
Allergy
ContraindicatedDo not take EMPAONE 25 TABLET if you are allergic to Empagliflozin.
Use In Pediatrics
ContraindicatedEMPAONE 25 TABLET is generally not recommended for use in children and adolescents (under 18 years of age). Consult your doctor before taking it.
Use In Geriatrics
Consult your doctorDue to limited therapeutic experience, elderly patients (above 75 years of age) should consult the doctor before taking EMPAONE 25 TABLET.
Others
Before taking EMPAONE 25 TABLET, inform your doctor if you:
- have type 1 diabetes (usually starts when you are young, and your body does not produce any insulin)
- might be at risk of dehydration (nausea, diarrhea, fever, not being able to eat or drink)
- serious infection of the urinary tract with fever
- have a serious infection called necrotising fasciitis of the perineum or Fournier’s gangrene (pain, tenderness, redness, or swelling of the genitals or the area between the genitals and the anus with fever or feeling generally unwell)
Interactions
A. Drug-Drug interactions:
Before taking EMPAONE 25 TABLET, inform your doctor if you are taking any of the following medicine:
- diuretics (used to lower blood pressure and fluid retention) Ex. Furosemide, chlorthalidone
- sulphonylureas (used to manage high blood sugar levels) Ex. Glimepiride, glyburide
Overdosage:
If you or anyone else accidentally take too much of EMPAONE 25 TABLET, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Empagliflozin |
| Pharmacological Category | : | Sodium Glucose Cotransporter-2 Inhibitor |
| Therapeutic Indication | : | Diabetes mellitus type-2, heart failure |
| Dosage Forms | : | Tablet |
More Information
- Keep EMPAONE 25 TABLET out of reach of children
- Do not store above 30°C
FAQs About EMPAONE 25 TABLET
Q: What is Empaone 25 Tablet used for?
A: Empaone 25 Tablet is used as an adjunct to manage type II diabetes. Studies have shown that it also exerts its effects on heart and kidneys and protect them from losing their functions.
Q: What does Empaone 25 Tab do to our body?
A: Empaone 25 Tab is an antidiabetic medicine. It works by inactivating certain proteins (sodium-glucose co-transporter-2 (SGLT-2)) found in the proximal tubules in the kidneys. This action facilitates excretion of excess glucose from the body in the form of urine, thereby bringing blood glucose levels to normal.
Q: What precautions must be followed while taking Empaone 25 Tablet?
A: Before taking Empaone 25 Tab, inform your doctor if you have type I diabetes, ketoacidosis, kidney disease, liver problems, severe dehydration, recent illness like fever, nausea, vomiting, and serious infections. Like for all diabetic patients it is important to check your feet regularly and adhere to any other advice regarding foot care given by your doctor. It is important to evaluate how your kidneys perform before and during management with this medicine. Avoid concomitant usage of diuretics (antihypertensive drugs) and other antidiabetic agents without consulting your doctor.
Q: How long does Empaone 25 Tablet take to work?
A: Empaone 25 Tablet usually takes 1-2 hours to start working. You may be able to see an improvement in blood sugar control levels within a week. However, this period may vary from person to person depending upon your health condition.
Q: When should I stop taking Empaone 25 Tablet?
A: Empaone 25 Tablet is used in the management of type II diabetes mellitus, which is a chronic condition. Therefore, it should be used chronically without discontinuation, unless recommended by your doctor.
Q: When can I see improvement in my condition after taking Empaone 25 Tablet?
A: You may be able to see an improvement in blood sugar control levels within a week after taking Empaone 25 Tablet. However, this period may vary from person to person depending upon your health condition.
Q: What is the use of Empaone 25 Tablet?
A: Empaone 25 Tablet is used as an adjunct to manage type II diabetes. Studies have shown that it also exerts its effects on heart and kidneys and protect them from losing their functions.
Q: Can Empaone 25 Tablet be taken during pregnancy?
A: It is unknown if empagliflozin is harmful to the unborn child. Therefore, do not take this medicine if you are pregnant or think you may be pregnant.
Q: What are the side effects of Empaone 25 Tablet?
A: The most common side effects of taking Empaone 25 Tablet are low blood sugar levels, urinary tract infections, dehydration, unusual thirst, light-headedness, fainting, genital yeast infection, skin rash and itching, passing more urine than usual, increased blood cholesterol levels and constipation.
Q: Is Empaone 25 Tablet safe?
A: Empaone 25 Tablet is considered safe when used under careful medical supervision. It effectively controls blood glucose levels at doses recommended by your physician.
Q: Can I stop taking Empaone 25 Tablet if my blood sugar levels are normal?
A: Consult your doctor before stopping therapy with Empaone 25 Tablet, as it is an antidiabetic medicine usually used on a long-term basis. However, if your blood glucose levels are under control, check your doctor for advice.
Q: Can Empaone 25 Tablet damage your kidneys?
A: As Empaone 25 Tablet primarily acts on the proximal tubules of the kidneys, it is not recommended for use in patients with kidney problems. Therefore, consult your doctor for advice before taking it.
Q: What is the best time to take Empaone 25 Tablet?
A: Empaone 25 Tablet can be taken with or without food. You can take the tablet at any time of the day. However, try to take it at the same time each day which will help you to remember taking it.
Q: Should I take Empaone 25 Tablet before or after food?
A: Empaone 25 Tablet can be taken with or without food. However, if you are unclear check with your doctor.
Q: Can Empaone 25 Tablet cause hypoglycemia?
A: Yes. Empaone 25 Tablet may cause hypoglycemia (low blood sugar levels). In such case, have a fruit juice, glucose tablets or gel, soft drinks, honey, or sugary candy. Check your blood sugar after 10 minutes. If not gained optimum level, take another sugary snack, or drink, and check the blood sugar again.
Q: What is the difference between metformin and Empaone 25 Tablet?
A: Empaone 25 Tablet is a SGLT-2 inhibitor, intended to manage type 2 diabetes by working on the kidneys to manage the absorption of glucose (blood sugar) resulting in decreased blood sugar level. Metformin is a biguanide which acts on stomach and liver to reduce the absorption of sugar that results in regulating the blood sugar level.
References
1. Joseph T. DiPiro, Robert L. Talbert, Gary C. Yee, Gary R. Matzke, Barbara G. Wells, L. Michael Posey. Diabetes Mellitus. Pharmacotherapy- A Pathophysiologic Approach. Eighth edition. Page-1263, 1264.
2. Uche Anadu Ndefo, Nicole O. Anidiobi, Efrah Basheer, and Angie T. Eaton. Empagliflozin (Jardiance): A Novel SGLT2 Inhibitor for the Treatment of Type-2 Diabetes. NIH National Library of Medicine, National center for biotechnology information. PMC. Pubmed Central. [Revised in January 2015] [Accessed on 18th April 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450666/
3. NHS Greater Glasgow and Clyde. Studies of Empagliflozin and Its Cardiovascular, Renal and Metabolic Effects (SUGAR-DM-HF). NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in September 2020] [Accessed on 18th April 2022] https://clinicaltrials.gov/ct2/show/NCT03485092
4. Boehringer Ingelheim Pharma GmbH & Co. KG. Electronic Medicines Compendium (EMC). [Revised in January 2022] [Accessed on 18th April 2022] https://www.medicines.org.uk/emc/files/pil.5441.pdf
Useful Diagnostic Tests
- Glucose-Fasting Blood
- Glucose-Postprandial Blood
- Glycosylated Hemoglobin
- Liver Function Test (LFT)
- Kidney Function Test (KFT)
- Complete Blood Count (CBC)
- Serum ketone test
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