New Revised MRP, 100% GST benefit passed Eglucent Mix 50 100IU Cartridge 3ml
Netmeds First Membership
Quick Links
Introduction About EGLUCENT MIX 50 100IU CARTRIDGE
EGLUCENT MIX 50 100IU CARTRIDGE contains Biphasic Insulin Lispro which belongs to the group of medicines called Antidiabetic agents. It improves glycemic control in patients with diabetes mellitus (both type I and type II). It helps your body to make utilize of the circulating blood glucose by transporting the circulating glucose from the blood into the muscles and fat tissues.
Biphasic Insulin Lispro is a pre-mixed combination of Insulin Lispro and Isophane (NPH) insulin. It is a fast-acting medicine where it begins to lower blood sugar levels within 10-20 minutes after administration.
Talk to your doctor before starting therapy with EGLUCENT MIX 50 100IU CARTRIDGE if you have any liver, kidney or heart problems. You must also inform your doctor if you have any hormonal problems, made sudden changes to your diet or perform intense exercise as a precaution.
Do not use this medicine if you have hypoglycemia (low blood sugar levels). Consult your doctor before using this medicine if you are pregnant or breastfeeding.
The most common side effects of receiving EGLUCENT MIX 50 100IU CARTRIDGE are low blood sugar levels, pain, redness, itching, swelling or thickening at the injection site, lump formation under the skin and swelling of body parts. Consult your doctor if any of these side effect troubles you.
Uses Of EGLUCENT MIX 50 100IU CARTRIDGE
- Improves glycemic control in patients with diabetes mellitus (both type I and type II)
How EGLUCENT MIX 50 100IU CARTRIDGE Works
Biphasic Insulin lispro is a combination of Insulin lispro and NPH. Insulin lispro is a fast-acting insulin that mimics the natural release of insulin by the pancreas in response to meals. It also helps control the postprandial (after-meal) rise in blood glucose. NPH slows down the absorption and extends the action of insulin. It provides a prolonged and more sustained release of insulin, helping to manage blood sugar levels between meals and overnight. Collectively, they help in controlling both immediate post-meals rise in blood sugar and the basal (background) insulin needs throughout the day.
How to use EGLUCENT MIX 50 100IU CARTRIDGE
Use EGLUCENT MIX 50 100IU CARTRIDGE under careful medical supervision. Inject EGLUCENT MIX 50 100IU CARTRIDGE into your thighs, buttocks, upper arm, or abdomen (i.e., subcutaneously). Do not administer this medicine into the vein or muscle directly. It should be administered at least 10 minutes before meals. Eat a meal or snack containing carbohydrates within 20 minutes of the injection to avoid low blood sugar.
Before administration, roll the vial/cartridge between your hands until the liquid becomes uniformly white and cloudy. While injecting, keep the needle under the skin for at least 6 seconds to make sure that the entire dose is injected.
Prior to the administration, visualize the cartridge/vial for any visible particulate matter and discoloration. Discard the needle and syringe after use and do not share your needles with others to avoid the risk of transmission of infections.
Avoid repeatedly injecting the medicine at the same site to manage skin damage. Instead, rotate the injection site. Make sure to consult your doctor before changing the injection site as a precaution.
EGLUCENT MIX 50 100IU CARTRIDGE should not be mixed with any other insulins before use. Do not stop therapy with EGLUCENT MIX 50 100IU CARTRIDGE without consulting your doctor. Your doctor will decide correct dose and frequency of administration depending upon your age, body weight and health condition.
Side Effects Of EGLUCENT MIX 50 100IU CARTRIDGE
Common
- Injection site reactions (such as pain, redness, itching or swelling)
- Lipodystrophy (shrinkage of fat tissues beneath the skin)
- Lumps under the skin
- Weight gain, swelling of body parts
- Hypoglycemia (Low blood sugar levels)
Uncommon
- Diabetic retinopathy (eye diseases due to diabetes)
- Swelling around the ankles and other joints
Rare
- Problem in vision
- Painful neuropathy (pain caused by nerve damage)
Consult your doctor immediately if you experience any of the following side effects:
- allergic reaction (generalized skin rash with itching, sweating, and swelling of layers under the skin, difficulties in breathing, palpitation, vomiting, stomach upset, reduction in blood pressure and fainting /loss of consciousness)
- signs of severe hypoglycemia (such as cold sweats, cool pale skin, headache, rapid heartbeat, nausea, increased hunger, temporary vision changes, drowsiness, tiredness and weakness, nervousness or tremor, anxiety, confusion and difficulty in concentrating)
- signs of heart failure (such as shortness of breath, localized swelling and weight gain with chest pain)
- signs of high blood sugar levels (such as nausea, vomiting, sleepiness, flushing, loss of appetite, thirst, fruity smell while breathing)
How To Manage Side Effects
Hypoglycemia
Managing hypoglycemia, or low blood sugar, involves prompt action to raise blood glucose levels and manage complications. When experiencing hypoglycemia, individuals should quickly consume a source of rapidly absorbed carbohydrates, such as glucose tablets, fruit juice, or regular soda. Waiting for about 15 minutes and rechecking blood sugar levels is crucial to ensure they rise to a safe range. If hypoglycemia persists, additional carbohydrate intake may be necessary. Once blood sugar levels stabilize, a small snack containing both carbohydrates and protein can help sustain them. Regular monitoring and consultation with a healthcare professional are essential for developing a personalized plan to manage hypoglycemia effectively. In severe cases, emergency assistance may be required.
Injection Site Reactions
Managing injection site reactions is essential for individuals who regularly administer injections. To alleviate discomfort and minimize potential issues, it is crucial to follow proper injection techniques. Rotate injection sites to manage overuse of a single area, allowing tissues to heal. Use a clean, sterile needle and syringe for each injection. Apply an ice pack to the injection site before and after administration to reduce pain and swelling. If redness, swelling, or irritation persists, consult a healthcare professional for guidance. It is essential to report any severe or persistent reactions to ensure appropriate adjustments to the injection routine and to manage potential complications.
Warning & Precautions
Pregnancy
Monitoring requiredEGLUCENT MIX 50 100IU CARTRIDGE can be used during pregnancy if prescribed by the physician. Therefore, consult your doctor before administration.
Breastfeeding
Use with CautionEGLUCENT MIX 50 100IU CARTRIDGE should be used with caution in breastfeeding women. However, consult your doctor before administration.
Driving and Using Machines
Use with CautionDo not drive or operate any heavy tools or machines if your ability is affected by EGLUCENT MIX 50 100IU CARTRIDGE.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking this medicine as it could aggravate your existing disease condition.
Kidney
Use with CautionEGLUCENT MIX 50 100IU CARTRIDGE should be used with caution in patients with kidney problems. Therefore, consult your doctor before administration.
Liver
Use with CautionEGLUCENT MIX 50 100IU CARTRIDGE should be used with caution in patients with liver problems. Therefore, consult your doctor before administration.
Allergy
ContraindicatedTalk to your doctor before receiving EGLUCENT MIX 50 100IU CARTRIDGE if you are allergic to Insulin Lispro, Isophane insulin or to any other insulin types (Ex. Lente, ultra-Lente).
Heart Disease
Use with CautionEGLUCENT MIX 50 100IU CARTRIDGE should be taken with caution in patients with heart disease. Therefore, consult your doctor before administration.
Use In Pediatrics
Consult your doctorConsult your doctor before injecting EGLUCENT MIX 50 100IU CARTRIDGE in children and adolescents (aged below 18 years).
Use In Geriatrics
Use with CautionEGLUCENT MIX 50 100IU CARTRIDGE should be used with caution in elderly patients (aged 65 years or above). Therefore, consult your doctor before administration. Proper dose adjustments and careful monitoring of blood glucose levels and kidney functions are required in such patients
Others
EGLUCENT MIX 50 100IU CARTRIDGE is not recommended for use if you:
- have or at risk of developing hypoglycemia (low blood sugar levels)
Talk to your doctor before administering EGLUCENT MIX 50 100IU CARTRIDGE if you:
- have problems in adrenal, pituitary or thyroid glands
- have recently changed your diet plan and lifestyle
- are exercising more than usual
- recently became ill or had any infections
- are planning to go abroad (as mealtime and injection timings may get changed)
- have or ever had stroke
Interactions
A. Drug-Drug interactions:
Before EGLUCENT MIX 50 100IU CARTRIDGE is administered, inform your doctor if you are taking any of the following medicines such as:
- Other antidiabetic agents such as sulfonylureas (Ex. tolbutamide, glibenclamide, glipizide), biguanides (Ex. metformin, phenformin), thiazolidinediones (Ex. pioglitazone), DPP-4 inhibitors (Ex. sitagliptin, vildagliptin) or SGLT-2 inhibitors (Ex. remogliflozin)
- Antidepressants (Ex. rasagiline, selegiline, phenelzine)
- Heart medicines (Ex. propranolol, atenolol, nebivolol) or ACE inhibitors (Ex. captopril, enalapril, lisinopril)
- salicylates (used to relieve pain or fever) Ex. aspirin
- sulfonamide antibiotics (Ex. sulfasalazine, sulfadiazine, sulfamethoxazole)
- oral contraceptives (birth control pills) Ex. mifepristone
- glucocorticoids (used to manage inflammation) Ex. cortisone, betamethasone, beclomethasone, dexamethasone, budesonide, prednisone
- thyroid hormone (Ex. thyroxine, triiodothyronine)
- sympathomimetic agents (Ex. ephedrine, adrenaline, salbutamol, or terbutaline)
- danazol (a medicine used for endometriosis)
- octreotide (used to manage diarrhea)
B. Interaction with food or drink:
EGLUCENT MIX 50 100IU CARTRIDGE should be administered at least 10 minutes before a meal.
Overdosage:
If you or anyone else took too much of this medicine, contact your doctor immediately or go to a hospital straight away as it may cause severe hypoglycemia. Symptoms of hypoglycemia might include fainting, feel unwell, sweating, vomiting, difficulty in breathing, fast heartbeat, and dizziness.
Synopsis
| Drug | : | Biphasic Insulin Lispro |
| Pharmacological Category | : | Insulin Preparations |
| Therapeutic Indication | : | Diabetes mellitus |
| Dosage Forms | : | Injection, Cartridge, Pre-filled syringe, Flex Pen |
More Information
- Keep out of reach of children
- Store the unopened pack in the refrigerator at 2-8°C. Do not freeze
- During use or when carried as a spare, keep it at room temperature
- Always place the vial/cartridge in the outer carton to protect from light
FAQs About EGLUCENT MIX 50 100IU CARTRIDGE
Q: Should EGLUCENT MIX 50 100IU CARTRIDGE be refrigerated?
A: Yes. An unopened pack must be stored in the refrigerator (2-8°C). During use or while carrying as a spare, keep it at room temperature to ensure uniform resuspension.
Q: Can EGLUCENT MIX 50 100IU CARTRIDGE be mixed with other insulins?
A: No. EGLUCENT MIX 50 100IU CARTRIDGE is already a pre-mixed combination of regular insulin and isophane insulin and therefore should not be mixed with other insulins. For more information regarding the direction of use contact your doctor.
Q: Is EGLUCENT MIX 50 100IU CARTRIDGE safe during pregnancy?
A: Yes. EGLUCENT MIX 50 100IU CARTRIDGE can be used during pregnancy if prescribed by the physician. Therefore, consult your doctor before administration.
Q: How long does it take for EGLUCENT MIX 50 100IU CARTRIDGE to start working?
A: EGLUCENT MIX 50 100IU CARTRIDGE is a fast-acting medicine where it begins to lower blood sugar levels about 10 minutes post administration and its effect would last for about 24 hours.
Q: Can EGLUCENT MIX 50 100IU CARTRIDGE be given intravenously?
A: No. EGLUCENT MIX 50 100IU CARTRIDGE is meant for subcutaneous use only (i.e., thighs, buttocks, abdomen, or upper arms). It should not be directly injected into the vein or muscle as it may cause severe hypoglycemia.
Q: What is the best area for injecting EGLUCENT MIX 50 100IU CARTRIDGE? Should I inject it only at the same site every day?
A: The best place for injecting this medicine is front of your thighs, buttocks, abdomen, or upper arms. The insulin would work more quickly if it were injected into the waist (abdomen). Do not repeatedly inject the medicine on the same site. Instead, rotate the injection sites within the same area to avoid the risk of developing lumps or skin pitting.
Q: What is EGLUCENT MIX 50 100IU CARTRIDGE used for?
A: EGLUCENT MIX 50 100IU CARTRIDGE improves glycemic control in patients with diabetes mellitus (both type I and type II). It helps your body to make utilize of the circulating blood glucose by transporting the circulating glucose from the blood into the muscles and fat tissues.
Q: What are the most common side effects of taking EGLUCENT MIX 50 100IU CARTRIDGE?
A: The most common side effects of receiving EGLUCENT MIX 50 100IU CARTRIDGE are low blood sugar levels, pain, redness, itching, swelling or thickening at the injection site, lump formation under the skin and swelling of body parts. Consult your doctor if any of these side effect troubles you.
Q: Can I stop therapy with EGLUCENT MIX 50 100IU CARTRIDGE without consulting your doctor?
A: No. You should not stop therapy with EGLUCENT MIX 50 100IU CARTRIDGE without consulting your doctor because it may lead to reversal of symptoms. If you feel better after using EGLUCENT MIX 50 100IU CARTRIDGE, consult your doctor for advice.
Q: Will taking a higher dose of EGLUCENT MIX 50 100IU CARTRIDGE be more effective?
A: No, taking a higher dose of EGLUCENT MIX 50 100IU CARTRIDGE will not be effective rather it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.
Q: Can I take medication for high blood pressure along with EGLUCENT MIX 50 100IU CARTRIDGE?
A: It is not advisable to take medicines to control blood pressure while taking EGLUCENT MIX 50 100IU CARTRIDGE without consulting your doctor. Therefore, consult your doctor before taking any antihypertensive medications along with EGLUCENT MIX 50 100IU CARTRIDGE as they have known interactions with EGLUCENT MIX 50 100IU CARTRIDGE.
References
1. KD. Tripathi. Insulin, Oral Hypoglycemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 265.
2. Noreen Islam; Niloufar R. Khanna; Patrick M. Zito. Insulin Lispro. StatPearls. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. August 2022. [Accessed on 23rd January 2024] https://www.ncbi.nlm.nih.gov/books/NBK507840/
3. Eli Lilly and Company Limited. Humalog® Mix25™ 100 units/ml suspension for injection in vial insulin lispro. European Medicines Compendium. [Revised in January 2021]. [Accessed on 23rd January 2024] https://www.medicines.org.uk/emc/files/pil.3829.pdf
4. Eli Lilly and Company Limited. Humalog® Mix50™ 100 units/ml suspension for injection in vial insulin lispro. European Medicines Compendium. [Revised in January 2021]. [Accessed on 23rd January 2024] https://www.medicines.org.uk/emc/files/pil.7474.pdf
Useful Diagnostic Tests
- HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
- Blood Glucose Fasting (FBS)
- Insulin-Fasting
- Netmeds Diabetic Checkup
- Advance Diabetes Monitoring (Senior Female)
Author Details
