Efimox ER Tablet 5'S

Introduction About EFIMOX ER TABLET

EFIMOX ER TABLET contains Amoxicillin which belongs to the group of medicines called Penicillins. EFIMOX ER TABLET is used in the management of tonsillitis (inflamed oval shaped pads of tissue at back of throat) and pharyngitis (inflammation of pharynx) that occur secondary to infection by Streptococcus pyogenes bacteria, in adults and paediatric patient (aged above 12 years).

EFIMOX ER TABLET is not recommended for use in patients allergic to amoxicillin or penicillin.  It is also not recommended for use in patients suffering from mononucleosis (viral infections caused by Epstein Bar Virus).

Before taking EFIMOX ER TABLET, inform your doctor if you have kidney problems, and/or liver problems (such as liver impairment).

EFIMOX ER TABLET should be used with caution in pregnant and breastfeeding women. The medicine can be used in children and adolescents (aged 12 to 18 years) after consulting the doctor.

The most common side effects reported after taking the medicine are development of fungal infection, diarrhoea, nausea and vomiting, along with pain in abdomen and head. Consult and inform your doctor if any of these symptoms worsens.

Uses Of EFIMOX ER TABLET

• Manage tonsillitis and pharyngitis that occur secondary to infection caused by bacteria Streptococcus pyogenes

How EFIMOX ER TABLET Works

EFIMOX ER TABLET works by inhibiting the synthesis of penicillin binding proteins which leads to activation of autolytic enzymes in bacterial cell wall resulting in lysis/destruction of bacterial cell wall thus providing relief from tonsillitis and pharyngitis in affected individuals.

How to use EFIMOX ER TABLET

Take EFIMOX ER TABLET as advised by your physician. Swallow the medicine with a glass full of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Side Effects Of EFIMOX ER TABLET

How To Manage Side Effects

Headache:

Stay hydrated and avoid taking products rich in caffeine and avoid harsh lights and loud sounds.  Apply a pain-relieving balm on forehead if needed.

Nausea and vomiting:

Try to take EFIMOX ER TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if symptom gets worse.

Warning & Precautions

Pregnancy

EFIMOX ER TABLET should be used with caution during pregnancy and in women planning for pregnancy. Consult and inform your doctor before taking the medicine.

Breastfeeding

EFIMOX ER TABLET should be used with caution in breastfeeding women. Consult and inform your doctor before taking the medicine.

 

Kidney

EFIMOX ER TABLET should be used with caution in patients diagnosed with kidney problems such as renal impairment. Consult and inform your doctor before taking it.

Liver

EFIMOX ER TABLET should be used with caution in patients diagnosed with liver problems. Consult and inform your doctor before taking it.

Allergy

Do not take EFIMOX ER TABLET if you are allergic to amoxicillin, penicillin and/or any other ingredients present in the medicine. Consult your doctor before taking the medicine.

Interactions

A. Drug-Drug Interactions:

Before taking EFIMOX ER TABLET, inform your doctor if you are taking any of the following medicine:

• oral contraceptives (medicines used for managing pregnancy) Ex.estrogen &  progestin, desogestrel & ethinyl estradiol

Overdosage:

If you or anyone else accidentally takes too much of EFIMOX ER TABLET, visit the nearby hospital or consult your doctor immediately. Symptoms of overdosage are interstitial nephritis (inflammation and swelling of spaces between the kidney tubules), and/or crystals in the urine (associated with signs such as cloudy urine, difficulty while urinating).

Synopsis

More Information

• Keep EFIMOX ER TABLET away from the reach of children.
• Store EFIMOX ER TABLET at 25°C

FAQs About EFIMOX ER TABLET

What is EFIMOX ER TABLET used for?

EFIMOX ER TABLET is used in the management of tonsillitis and pharyngitis, that occur secondary to infection by Streptococcus pyogenes bacteria, in adults and paediatric patient (aged above 12 years).

Can I take EFIMOX ER TABLET in pregnancy?

EFIMOX ER TABLET is recommended to be taken with caution by pregnant women and/or women who are planning pregnancy. It is recommended to inform and consult your doctor before taking the medicine.
Can I take EFIMOX ER TABLET for viral infection?

No, EFIMOX ER TABLET is an antibiotic which is used only to manage bacterial infections. It is not recommended for use to manage viral infections especially mononucleosis, a viral infection caused by  Epstein Bar Virus, generally characterized by symptoms such as fever, rash and swollen glands.

How to take EFIMOX ER TABLET?

Take EFIMOX ER TABLET as advised by your physician. Swallow the medicine with a glass full of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

What are the common side effects of EFIMOX ER TABLET?

The most common side effects reported after taking the medicine are development of fungal infection, diarrhoea, nausea and vomiting, along with pain in abdomen and head. Consult and inform your doctor if any of these symptoms worsens.

 What medicines shall I avoid while taking EFIMOX ER TABLET?

It is recommended to not take medicines used for oral contraception (prevention of pregnancy) such as estrogen & progestin, desogestrel & ethinyl estradiol. Consult your doctor before taking it.

References

1. KD. Tripathi. Beta-Lactam Antibiotics Essentials of medical pharmacology. Seventh edition. 2013. Page- 723

2. Bobak J. Akhavan; Niloufar R. Khanna; Praveen Vijhani. Amoxicillin. NIH National Library of Medicine. National Center for Biotechnology Information. StatPearls [Internet]. August 2021. [Accessed on 6th October 2022] https://www.ncbi.nlm.nih.gov/books/NBK482250/

3. Giarratano A, Green SE, Nicolau DP. Review of antimicrobial use and considerations in the elderly population. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [ Revised in April 2018] [Accessed on 6th October 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909780/ 

4. Andrade RJ, Tulkens PM. Hepatic safety of antibiotics used in primary care. NIH National Library of Medicine. National Center for Biotechnology Information. [Revised in July 2011] [ Accessed on 6th October 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112029/

5. Angela Giarratano, Samantha EL Green, and David P Nicolau. Review of antimicrobial use and considerations in the elderly population. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central.  [Revised 17th August 2021] [Accessed on 6th October 2022] https://www.ncbi.nlm.nih.gov/books/NBK482250/

6. Moxtag. Vernalis Research. [Revised on 2nd October 2015] [Accessed on 6th October 2022] https://www.vernalis.com/vernalis-plc-acquires-us-rights-to-moxatag/

Useful Diagnostic Tests

• Bacterial Culture test
• Liver function test
• Kidney Function test

Author Details

Written By Dr. K .AZEEM HUSSAIN - B.D.S

Reviewed For Accuracy By Dr. Salem Gill - MBBS

Last updated on 12 Oct 2022 | 02:19 PM(IST)