EBOV PG Tablet 10's

Introduction About EBOV PG 50 TABLET

EBOV PG 50 TABLET is a combination of Etoricoxib and Pregabalin which belongs to the group of medicines called Nonsteroidal Anti-inflammatory drugs (NSAIDs) and Anticonvulsants respectively. It is used for the management of neuropathic pains associated with spinal cord injury, diabetic peripheral neuropathy (nerve damages with numbness, loss of sensation, and sometimes pain in your feet, legs, or hand due to high sugar levels), fibromyalgia (pain in soft tissues and muscles all over the body) and post herpetic neuralgias (burning pain in nerves mainly after shingles infection).

It is not recommended to take EBOV PG 50 TABLET if you have serious liver diseases, kidney diseases, inflammatory bowel diseases, gastrointestinal bleeding, congestive heart failure, increased blood pressure and inflammatory bowel diseases. EBOV PG 50 TABLET is not recommended during pregnancy and lactation unless it is clearly necessary. Do not give EBOV PG 50 TABLET to children and adolescents below 16 years of age. Consult your doctor for before taking.

EBOV PG 50 TABLET should be taken only under medical supervision as there is a chance of developing addiction, dependence and withdrawal reactions. The most common side effects of taking EBOV PG 50 TABLET includes dizziness, sleepiness, difficulty in concentrating, dry mouth, blurred vision, weight gain, swelling of hands or feet, cold and flu symptoms, and irregular heartbeat. Consult your doctor if any of these symptoms gets worsened for you while taking EBOV PG 50 TABLET.

Uses Of EBOV PG 50 TABLET

It is used to manage neuropathic pain associated with:

• spinal cord injury
• diabetic peripheral neuropathy
• fibromyalgia
• post herpetic neuralgia

How EBOV PG 50 TABLET Works

EBOV PG 50 TABLET is a combination of Etoricoxib and Pregabalin. Etoricoxib is a selective Cox 2 inhibitors that relieves pain by blocking the effects of cox 2 (cyclooxygenase 2) enzymes that are responsible for the production of prostaglandins (pain and inflammation). Pregabalin relieves pain by reducing the release of neurotransmitters by decreasing calcium influx at nerve endings.

How to use EBOV PG 50 TABLET

Take EBOV PG 50 TABLET as advised by your doctor. Swallow EBOV PG 50 TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose, duration of management based on your age, body weight and severity of conditions.

Side Effects Of EBOV PG 50 TABLET

How To Manage Side Effects

Bloating

Stick to simple meals. Drink enough fluids. Avoid eating oily, fried, or spicy foods. Take adequate rest. Consult doctor before taking any medication.

Constipation

Drink adequate amount of water. Include plenty of fruits and vegetables in your daily diet. Avoid smoking and alcohol consumption. Eat a well-balanced diet. Do exercises regularly.  Consult your doctor before taking any medicines.

Dry Mouth

Drink plenty of water and fruit juices and consume soft foods with higher water and fibre content.

Headache

Rest and relax. Drink plenty of fluids such as water. Apply a pain balm on your forehead and massage if needed. Consult doctor before taking any medication.

Indigestion

Eat a balanced diet. Avoid consumption of alcohol. Reduce the intake of spicy food. Drink plenty of water and other fluids to stay hydrated.

Nausea And Vomiting

Drink lots of water and fruit juices. Eat simple and light meals throughout the day. Stay away from oil rich and spicy foods. Consult your doctor if the symptoms are worsening.

Warning & Precautions

Pregnancy

Monitoring required

EBOV PG 50 TABLET is not recommended to take during pregnancy unless it is clearly necessary due to the lack of safety data. Consult your doctor before taking EBOV PG 50 TABLET.

Breastfeeding

Contraindicated

EBOV PG 50 TABLET is not recommended to take during breastfeeding. Consult your doctor before taking it.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you feel dizziness, sedation, reduction in mental alertness, blurring of vision, somnolence after taking EBOV PG 50 TABLET.

Alcohol

Contraindicated

Consumption of alcohol is not recommended while taking EBOV PG 50 TABLET as it may increase the risk of side effects.

Kidney

Contraindicated

EBOV PG 50 TABLET is not recommended to be taken in patients with severe kidney diseases. Consult your doctor before taking it.

Liver

Consult your doctor

EBOV PG 50 TABLET is not recommended for use if you have severe liver diseases. EBOV PG 50 TABLET should be taken with caution in patients diagnosed with liver diseases. Consult your doctor before taking EBOV PG 50 TABLET.

Allergy

Contraindicated

Do not take EBOV PG 50 TABLET if you are allergic to Etoricoxib, Pregabalin or any other ingredients of this medicine.  

Heart Disease

Contraindicated

EBOV PG 50 TABLET is not recommended to be taken in patients with increased blood pressure, congestive heart failure or any other heart diseases. Consult your doctor before taking EBOV PG 50 TABLET.

Use In Pediatrics

Contraindicated

EBOV PG 50 TABLET is not recommended for children and adolescents below 16 years of age due to the lack of safety data. Consult your doctor before taking.

Use In Geriatrics

Use with Caution

EBOV PG 50 TABLET should be used with caution to elderly people as they are at a higher risk of developing side effects such as dizziness, somnolence, reduced mental alertness, confusion. Consult your doctor before giving EBOV PG 50 TABLET to elderly people.

Interactions

A. Drug-Drug interactions:

Before taking EBOV PG 50 TABLET, inform your doctor if you are taking any of the following medicines:

• phenytoin, carbamazepine, lamotrigine, valproic acid (medicine used to manage fits)
• lorazepam (medicine used to manage anxiety)
• oxycodone (medicine used to manage pain)
• ethanol (medicine used to manage infections)
• diuretics (Ex. chlorothiazide, chlorthalidone)
• angiotensin II antagonists (Ex. telmisartan, losartan)
• acetyl salicylic acid (medicine used to relieve minor pain)
• cyclosporin, tacrolimus (medicine used to manage body from rejecting transplanted organ)
• methotrexate (medicine used to calm immune system)
• lithium (medicine used to manage mania)
• estradiol, norethindrone (medicine used to manage unwanted pregnancy)
• minoxidil (medicine used to manage hair fall)
• salbutamol (medicine used to manage cough)
• rifampicin (medicine used to manage tuberculosis)

Overdosage:

If you or anyone else accidentally took too much of EBOV PG 50 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage includes somnolence, confusions, agitation, restlessness, fits.

Synopsis

More Information

• Keep EBOV PG 50 TABLET out of sight and reach of children
• Store EBOV PG 50 TABLET at room temperature

FAQs About EBOV PG 50 TABLET

Q: What is EBOV PG 50 TABLET used for?

A: EBOV PG 50 TABLET is used for the management of neuropathic pains associated with spinal cord injury, diabetic peripheral neuropathy (nerve damages with numbness, loss of sensation, and sometimes pain in your feet, legs, or hand due to high sugar levels), fibromyalgia (pain in soft tissues and muscles all over the body) and post herpetic neuralgias (burning pain in nerves mainly after shingles infection).

Q: Can I drive while taking EBOV PG 50 TABLET?

A: Do not drive or operate any machines if you feel dizziness, sedation, reduction in mental alertness, blurring of vision, somnolence after taking EBOV PG 50 TABLET.

Q: Is it safe to take EBOV PG 50 TABLET during pregnancy?

A: It is not recommended to take EBOV PG 50 TABLET during pregnancy unless it is clearly necessary due to the lack of safety data. Consult your doctor before taking EBOV PG 50 TABLET.

Q: what are the common side effects of taking EBOV PG 50 TABLET?

A: The most common side effects of taking EBOV PG 50 TABLET includes dizziness, sleepiness, difficulty in concentrating, dry mouth, blurring of vision, weight gain, swelling of hands or feet, cold and flu symptoms, and irregular heartbeat. Consult your doctor before taking EBOV PG 50 TABLET.

Q: How EBOV PG 50 TABLET works?

A: Etoricoxib is a selective Cox 2 inhibitors that relieves pain by blocking the effects of cox 2 (cyclooxygenase 2) enzymes that are responsible for the production of prostaglandins that are responsible for pain and inflammation. Pregabalin relieves pain by reducing the release of neurotransmitters by decreasing calcium influx at nerve endings.

References

1. KD Tripathi. NSAIDS and antipyretic -Analgesics. Essentials of Medical pharmacology eighth edition (2019), page number – 222.

2. KD Tripathi. Antiepileptic drugs. Essentials of Medical pharmacology eighth edition (2019), page number – 446.

3. Alan. K Matsumoto, Paul F. Etoricoxib. National Library of medicine. National centre for Biotechnology information. PubMed (2004). [Accessed on 8th March 2023] https://pubmed.ncbi.nlm.nih.gov/15319795/#:~:text=It%20is%20a%20member%20of,nonsteroidal%20antiinflammatory%20drugs%20(NSAIDs)

4. Torrent pharma. Pregabalin. [Revised in May 2017] [Accessed on 8th March 2023] https://www.torrentian.com/pisheet/Upload/PI_Sheet/1505.pdf

5. Torrent Pharma. Etoricoxib. [Revised in September 2016] [Accessed on 8th March 2023] https://www.torrentian.com/pisheet/Upload/PI_Sheet/1960.pdf

6. Etoricoxib + Pregabalin. Leeford Pharma. [Accessed on 8th March 2023] https://www.leeford.in/product/780/pregabanyl-et

7. Etoricoxib + Pregabalin. Lareon pharma. [Accessed on 8th March 2023] https://www.larenon.com/wp-content/uploads/2021/08/PBREN-ET_-LBL.pdf

8. Etoricoxib + Pregabalin. Osian biotech. [Accessed on 8th March 2023] https://osiantebiotech.com/product/etoricoxib-60mg-pregabalin-75mg/

9. Etoricoxib + Pregabalin. Numera life sciences. [Accessed on 8th March 2023] https://www.numeralifesciences.com/etoricoxib-60mg-pregabalin-75-mg

10. Pregabalin. Drug bank. [Revised in March 2023] [Accessed on 8th March 2023] https://go.drugbank.com/drugs/DB00230

11. Etoricoxib. Drug bank. [Revised in May 2021] [Accessed on 8th March 2022] https://go.drugbank.com/drugs/DB01628

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed For Accuracy By Dr. Sankara Babu Gorle - MBBS, MD (Pharmacology)

Last updated on 09 Mar 2023 | 12:48 PM(IST)