Mankind Pharma Pvt Ltd

Dynaglipt 20mg Tablet 10'S

Diabetes
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    Introduction About DYNAGLIPT 20MG TABLET

    What is Dynaglipt 20mg?

    Dynaglipt 20mg belongs to the class of DPP-4 inhibitors, used to manage type 2 diabetes mellitus. It works by increasing insulin production and reducing sugar levels in the blood.

    Dynaglipt 20mg regulates blood sugar levels, improves insulin response and easy-to-take oral medication.

    Take one tablet daily with or without food, as prescribed by your doctor. Do not exceed the recommended dose.

    Dynaglipt 20mg is not recommended for type 1 diabetes or diabetic ketoacidosis. Inform your doctor if you have kidney or liver issues. Pregnant or breastfeeding women should consult a healthcare provider before taking Dynaglipt 20mg.

    The common side effects include headache, sore throat, and mild gastrointestinal issues. Consult your physician if symptoms persist or worsen.

    Uses Of DYNAGLIPT 20MG TABLET

    • Used to manage Type II diabetes mellitus

    Benefits of DYNAGLIPT 20MG TABLET

    1. Regulates blood sugar levels:

    • Dynaglipt 20mg helps maintain optimal blood glucose levels, particularly in patients with Type 2 Diabetes
    • It reduces post-meal blood sugar spikes and supports steady sugar control throughout the day

    2. Improves insulin response:

    • By enhancing the action of incretin hormones, Dynaglipt boosts the body’s natural insulin production in response to meals and reduces excessive glucose release from the liver, improving overall insulin efficiency

    3. Easy-to-take oral medication:

    • This tablet is taken orally, once daily, with or without food, offering a hassle-free alternative to injections
    • It’s simplicity increases management adherence and long-term diabetes control

    How DYNAGLIPT 20MG TABLET Works

    How it helps in diabetes management:

    1. Enhancing incretin hormone activity:

    • Incretins are natural hormones that help regulate blood sugar
    • Dynaglipt increases the levels of these hormones, which stimulate insulin release after meals, decrease glucose production in the liver, help lower blood sugar levels more effectively

    2. Controlling post-meal glucose spikes:

    • One of the major challenges in diabetes is managing blood sugar after eating. Dynaglipt targets this phase specifically, helping to manage sudden sugar spikes

    3. Reducing the risk of hypoglycemia:

    • Unlike some other diabetes medications, Dynaglipt does not cause significant drops in blood sugar when used alone, making it safer and well-tolerated for most patients

    4. Supporting long-term glycemic control

    • Regular use of Dynaglipt, as prescribed by a doctor, helps in maintaining HbA1c levels, a key marker of long-term blood glucose control

    How to use DYNAGLIPT 20MG TABLET

    Recommended dosage of Dynaglipt 20mg:

    • One tablet (20 mg) of Dynaglipt 20mg once daily
    • It can be taken with or without food
    • It should be taken at the same time each day for best results

    Instructions for use for Dynaglipt 20mg:

    • Take one tablet once daily, or as directed by your doctor
    • Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet
    • It can be taken with or without food, but try to take it at the same time every day to maintain a consistent level in your bloodstream
    • It should be preferably taken at the same time daily (e.g., morning with breakfast)

    What if I forgot to take DYNAGLIPT 20MG TABLET

    • Take the missed dose as soon as you remember
    • If it is almost time for your next scheduled dose, skip the missed dose
    • Do not double up to catch up for the missed dose

    Side Effects Of DYNAGLIPT 20MG TABLET

    Common side effects of Dynaglipt 20mg

    • headache
    • sore throat
    • mild gastrointestinal issues

    How To Manage Side Effects

    Headache

    • Drink plenty of water throughout the day
    • Maintain balanced meals with proteins, healthy fats, and fiber
    • Aim for 7-8 hours of restful sleep

    Sore Throat

    • Gargle with warm water or a saline solution after inhalation to remove residual medication
    • Drink plenty of water to soothe the throat and keep it moist
    • Warm herbal teas with ginger, chamomile, or licorice may also provide relief

    Stomach Discomfort

    • Include fiber-rich foods like vegetables, whole grains, and fruits to aid digestion
    • Avoid spicy, greasy, or processed foods, which can aggravate stomach discomfort
    • Gentle physical activity like walking after meals can help improve digestion and reduce bloating

    Warning & Precautions

    Pregnancy

    Monitoring required

    Animal studies have not demonstrated significant teratogenic effects. However, due to the absence of comprehensive human studies, Teneligliptin should only be used during pregnancy if the potential benefits justify the potential risks to the fetus.

    Breastfeeding

    Contraindicated

    Animal studies indicate that Teneligliptin is excreted in milk. The presence of Teneligliptin in human breast milk is unknown, and its effects on the nursing infant have not been studied. Therefore, breastfeeding is not recommended during treatment with Teneligliptin.

    Driving and Using Machines

    Use with Caution

    Do not drive or operate any machines if you feel dizzy after taking Dynaglipt 20mg.

    Alcohol

    Consult your doctor

    Avoid consumption of alcohol while taking Dynaglipt 20mg as it may increase the risks of side effects.

    Liver

    Use with Caution

    Dynaglipt 20mg should be used with caution in patients with severe liver diseases.

    Allergy

    Contraindicated

    Do not take Dynaglipt 20mg if you are allergic to Teneligliptin or any of the other ingredients of this medicine.

    Heart Disease

    Use with Caution

    Dynaglipt 20mg should be used with caution in patients with heart problems (like heart failure or slow heartbeat).

    Use In Pediatrics

    Consult your doctor

    There is no proper information regarding the use of Dynaglipt 20mg in children and in adolescents (below 18 years).

    Use In Geriatrics

    Use with Caution

    Dynaglipt 20mg should be used with caution in elderly patients. Therefore, consult your doctor before taking the medicine. Proper dose adjustments and careful monitoring are required in such patients.

    Other Warnings for DYNAGLIPT 20MG TABLET

    Before taking Dynaglipt 20mg, inform your doctor if you:

    • have pituitary insufficiency or adrenal insufficiency
    • are malnourished, starved, on an irregular diet, or feeling weak
    • perform extreme muscle exercises
    • have a history of abdominal operation or intestinal obstruction
    • have hypokalaemia (low blood potassium levels)

    Who should not take [GBNKEYWORD

    Dynaglipt 20mg is not recommended for use if you:

    • have severe ketosis (increased levels of ketone bodies in the blood)
    • have diabetic coma or precoma
    • have type I diabetes mellitus
    • have serious traumatic injury

    Diet and Lifestyle Advice

    Best foods to eat while Dynaglipt 20mg:

    • Brown rice, quinoa, whole wheat bread, oats
    • Lentils, chickpeas, kidney beans
    • Spinach, kale, broccoli, carrots
    • Apples, pears, oranges, berries
    • Eggs, chicken, fish, tofu & paneer
    • Broccoli, cauliflower, cabbage

    Exercise tips to enhance the effectiveness of Dynaglipt 20mg:

    • Cardiovascular (Aerobic) Exercises
    • Strength Training – Builds Muscle & Burns Fat
    • Flexibility & Balance Exercises – Manages Diabetes-Related Complications
    • High-Intensity Interval Training (HIIT) – Quick & Effective

    Foods & drinks to avoid while on Dynaglipt 20mg:

    • Sugary foods & high-carb processed foods
    • Fried & fatty foods
    • Alcohol & caffeinated drinks
    • High-sodium foods
    • Dairy products with added sugar & artificial sweeteners

    How to balance your diet to manage blood sugar spikes:

    • Prioritize low-glycemic index (GI) foods
    • Eat more protein with every meal
    • Add healthy fats for better blood sugar control
    • Control carbohydrate intake
    • Stay hydrated & avoid sugary drinks
    • Eat at regular intervals
    • Plan a balanced plate (the diabetes plate method)

    Drug - Drug interaction

    Drug/Drug Class

    Interaction Type

    Possible Effect

    Recommendation

    Sulfonylureas (e.g., Glimepiride)

    Additive Hypoglycemic Effect

    May increase risk of low blood sugar (hypoglycemia)

    Monitor blood sugar; dosage adjustment may be needed

    Metformin

    Complementary Action

    Safe, often prescribed together for improved glycemic control

    Usually co-administered

    Insulin

    Additive Hypoglycemic Effect

    Risk of hypoglycemia when used with Teneligliptin

    Close monitoring and possible dose reduction

    Rifampicin (antibiotic)

    Enzyme Inducer

    May reduce effectiveness of Dynaglipt by increasing metabolism

    Monitor blood sugar levels

    Corticosteroids (e.g., Prednisone)

    Antagonistic Effect

    May raise blood sugar, reducing Dynaglipt's effectiveness

    Monitor glucose closely

    Thiazide diuretics

    Hyperglycemic Potential

    Can increase blood glucose levels

    Monitor and adjust therapy as needed

    Beta-blockers (e.g., Atenolol)

    Masking Effect

    May mask symptoms of hypoglycemia (e.g., rapid heartbeat)

    Use with caution; patient education needed

    Alcohol

    Unpredictable Effect

    May enhance or reduce blood sugar unpredictably

    Limit or avoid alcohol

    Synopsis

    Drug :   Teneligliptin
    Pharmacological Category :   Dipeptidyl Peptidase-4 Inhibitors
    Therapeutic Indication :   Type II Diabetes mellitus                     
    Dosage Forms :   Tablet

    More Information

    How Dynaglipt 20mg compares to other DPP-4 inhibitors:

    Feature

    Dynaglipt (Teneligliptin)

    Sitagliptin

    Saxagliptin

    Linagliptin

    Dosage

    20 mg once daily

    100 mg once daily

    5 mg once daily

    5 mg once daily

    Half-Life

    ~24 hours

    ~12 hours

    ~2.5 hours

    ~12 hours

    Renal Adjustment Needed?

    No (mild to moderate CKD)

    Yes

    Yes

    No

    Liver Adjustment Needed?

    Use with caution

    Generally safe

    Safe

    Safe

    Weight Neutral?

    Yes

    Yes

    Yes

    Yes

    Hypoglycemia Risk (Monotherapy)

    Low

    Low

    Low

    Low

    Combination Therapy Use

    Metformin, sulfonylureas, insulin

    Same

    Same

    Same

    Cost (India)

    Lower (more affordable)

    Higher

    Higher

    Higher

    Availability in India

    Widely available

    Widely available

    Limited

    Limited

     

    Side effects you should not ignore:

    Symptom

    What it may indicate

    What to do

    Severe abdominal pain

    Possible pancreatitis

    Stop medication and consult a doctor right away

    Persistent sore throat or fever

    Possible infection or low white blood cell count

    Get medical advice promptly

    Skin rash, itching, or swelling

    Allergic reaction or hypersensitivity

    Discontinue use and seek emergency care

    Dizziness or fainting

    Blood sugar fluctuation or low blood pressure

    Monitor sugar levels, consult your doctor

    Shortness of breath or chest tightness

    Possible cardiac or respiratory reaction

    Seek urgent medical attention

    Yellowing of eyes or skin

    Liver dysfunction

    Stop taking and get liver function tests done

    Unusual fatigue or weakness

    Possible lactic acidosis (especially with metformin)

    Immediate evaluation needed

     

    Interaction warnings with common foods:

    Item

    Effect

    Advice

    High-sugar foods

    Counteracts medication effect

    Follow a diabetes-friendly diet

    Grapefruit juice

    No known major interaction with Teneligliptin

    Can be consumed, unless advised otherwise

    Caffeine

    May worsen headache side effects in sensitive users

    Consume in moderation

     

    What makes Dynaglipt cheaper or cost-effective?

    1. Indian-Manufactured Generic:

    • Dynaglipt is manufactured by Indian pharmaceutical companies, which lowers production and distribution costs

    2. No Patent-Related Premium:

    • Teneligliptin’s patent has expired or is not enforced in several countries, allowing multiple brands to market it
    • The absence of patent restrictions results in healthy competition and price reduction

    3. Single-Ingredient Formulation:

    • Unlike combination pills (e.g., with metformin), Dynaglipt contains only Teneligliptin, reducing manufacturing complexity and cost

    4. Fewer Monitoring Requirements:

    • Since Dynaglipt does not require renal dose adjustment in most cases, it reduces the need for expensive routine lab monitoring

    5. Widely Available in India:

    • Approved and marketed in India since 2013, Teneligliptin has widespread availability across urban and rural regions, keeping prices competitive

    Is there a cheaper alternative to Dynaglipt? Or You may also like:

    • TELNIGLIP 20mg Tablet
    • TENLIPTIN 20mg Tablet

    Type 2 Diabetes Mellitus:

    Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disorder characterized by high blood sugar levels due to insulin resistance and/or reduced insulin production. If left untreated, it can lead to serious complications like heart disease, kidney damage, and nerve disorders.

    • Insulin resistance - Body cells do not respond effectively to insulin
    • Pancreatic dysfunction - Reduced insulin production over time
    • Genetics & family history - Higher risk if a parent or sibling has diabetes
    • Unhealthy lifestyle - Poor diet, obesity, and lack of exercise contribute
    • Hormonal imbalances – Conditions like PCOS and thyroid disorders can increase risk

    Common symptoms of Type 2 Diabetes:

    • Excessive thirst and frequent urination
    • Unexplained weight loss or weight gain
    • Fatigue and low energy
    • Blurred vision
    • Slow wound healing and frequent infections

    How type 2 Diabetes Progresses:

    1. Early Stage: Mild insulin resistance, high fasting glucose levels

    2. Intermediate Stage: Increased insulin resistance, post-meal sugar spikes

    3. Advanced Stage: Significant insulin deficiency, requiring medications like Dynaglipt M or insulin therapy

    FAQs About DYNAGLIPT 20MG TABLET

    Q: What is Dynaglipt 20mg used for?

    A: Dynaglipt 20mg contains Teneligliptin which is used to manage type II diabetes (high blood sugar levels) in adults, that cannot be controlled by diet and exercise alone. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

    Q: Can I take Dynaglipt 20mg with other diabetes medications?

    A: Yes, Dynaglipt 20mg but only under medical supervision to avoid hypoglycemia.

    Q: Can I drink alcohol while on Dynaglipt?

    A: It is not recommended to consume alcohol while taking Dynaglipt 20mg Tablet, especially if you are being managed for type 2 diabetes.

    Q: Is Dynaglipt 20mg safe to use in pregnancy?

    A: Dynaglipt 20mg should be used in pregnant women only if prescribed by the physician. Your doctor may prescribe Dynaglipt 20mg for you after evaluating the risks and benefit ratio.

    Q: What precautions do I need to follow while taking Dynaglipt 20mg?

    A: Before taking Dynaglipt 20mg, inform your doctor if you have any liver or heart problems. You must also inform your doctor if you have hormonal problems, stomach problems (surgery in the gut) or if you are malnourished. Dynaglipt 20mg is not suitable for use in patients with type I diabetes mellitus.

    Q: Can I take medication for high blood pressure along with Dynaglipt 20mg?

    A: No. It is not advisable to take medicines to control blood pressure while taking Dynaglipt 20mg without consulting your doctor.

    Q: What should I do if I experience low blood sugar after taking Dynaglipt 20mg?

    A: Low blood sugar is a common side effect of taking Dynaglipt 20mg. Try to have sugar rich food items such as fruit juice, glucose tablets or gel, soft drinks, honey, or sugary candy. Check your blood sugar after 10 minutes. If not gained optimum level, take another sugary snack, or drink, and check the blood sugar again. In case of persistent low blood sugar levels, consult your doctor immediately.

    Q: How does Dynaglipt work in diabetes management?

    A: Dynaglipt 20mg contains Teneligliptin, which belongs to a class of medications called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). It helps manage type 2 diabetes mellitus by improving blood sugar control.

    Q: Can Dynaglipt cause dizziness?

    A: Yes. Dizziness is a common side effect of using Dynaglipt. In case you experience dizziness, lie down until it passes, then get up slowly and carefully. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, and alcohol. Do not drive or use machinery to avoid accidents.

    Q: Can Dynaglipt be taken with insulin?

    A: Co-administration of Dynaglipt with insulin is considered risky as they are increased chances of hypoglycemia (decreased blood sugar levels).

    Q: How to take Dynaglipt?

    A: You must take Dynaglipt as advised by your physician. Try to take this medicine preferably after meals and swallow it with a glass of water. Do not crush or chew the medicine.

    Q: How much Dynaglipt 20mg should I take?

    A: Dynaglipt 20mg should be used only under medical supervision. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body condition and severity of the disease condition.

    References

    1. Joseph T. DiPiro, Robert L. Talbert, Gary C. Yee, Gary R. Matzke, Barbara G. Wells, L. Michael Posey. Diabetes Mellitus. Pharmacotherapy- A Pathophysiologic Approach. Eighth edition. Page- 1263, 1264.

    2. Mitra, A., & Ray, S. Evaluation of the Safety and Efficacy of Teneligliptin at a Higher Dose in Indian Type 2 Diabetes Patients: A Retrospective Analysis. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. January 2020. [Accessed on 11 April 2025]

    3. Torrent Pharmaceutical Ltd. Teneligliptin. [Revised in April 2021] [Accessed on 11 April 2025]

    4. Mitsubishi Tanabe Pharma Factory Ltd. Teneligliptin. [Revised in April 2020] [Accessed on 11 April 2025]

    Author Details

    Written By Dr. Janet.C - Pharm.D
    Reviewed For Accuracy By Dr. Jaya Prabakaran - MBBS, MD (Diabetology and Family Medicine)
    Last updated on 15 Apr 2025 | 09:42 AM(IST)
    Lab updated