Durasalyn Paed Liquid 100ml

Introduction About DURASALYN PAED LIQUID

DURASALYN PAED LIQUID contains bromhexine, choline theophyllinate, and Salbutamol which belong to the group of medicines called mucolytic agents, and bronchodilators respectively. It is used for the management of asthma, bronchospasm, bronchitis, respiratory diseases, apnoea (shortness of breath) and bradycardia (slower heart rate).

Bronchospasm is a condition where muscles inside the lungs get tightened. Symptoms include coughing, wheezing, tightness in the chest, and tiredness. Bronchitis is an inflammation of the bronchi (the air passage into the lungs), with symptoms of coughing up thickened mucus and shortness of breath.

Before taking DURASALYN PAED LIQUID, inform your doctor if you are suffering from high blood pressure, an overactive thyroid gland, diabetes, heart problems with an increased heart rate, a stomach ulcer, etc. DURASALYN PAED LIQUID is not recommended for pregnant or breastfeeding women. DURASALYN PAED LIQUID is recommended for use in children over 2 years of age.

The most common side effects of taking DURASALYN PAED LIQUID include vomiting, an increased heart rate, a fall in blood pressure, fits, dehydration, increased urine production, and frequent urination. Consult your doctor if any of your symptoms get worse.

Uses Of DURASALYN PAED LIQUID

• Manage asthma (difficulty in breathing, coughing, wheezing, difficulty in breathing)
• Manage bronchospasm (bronchospasm is a condition where muscles inside the lungs get tightened with symptoms of cough, wheezing, tightness in the chest, and tiredness)
• Manage bronchitis ( inflammation  of bronchi with symptoms of coughing up thickened mucus and shortness of breath)
• Manage apnoea(shortness of breath)
• Manage respiratory diseases (cough, cold)
• Manage slower heart rate (bradycardia)

How DURASALYN PAED LIQUID Works

DURASALYN PAED LIQUID contains bromhexine, choline, theophylline, and salbutamol. Bromhexine is a mucolytic agent that manages the hypersecretion of mucus. It works by making your mucus thinner and less viscous so that you can get rid of it easily by coughing. Choline theophyllinate and salbutamol are bronchodilators that relax the muscles of the airways in the lungs and make the airways stay open, which makes it easier to breathe.

Taking salbutamol increases the heart rate, so it is used to manage slower heart rates as well. Theophylline blocks cough reflux by decreasing the excitability of sensory nerves, and thus it helps in the management of cough.

How to use DURASALYN PAED LIQUID

Take DURASALYN PAED LIQUID as advised by your physician. Shake well before use. You can take DURASALYN PAED LIQUID with or without food. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.

Side Effects Of DURASALYN PAED LIQUID

How To Manage Side Effects

Diarrhea

Keep yourself hydrated by drinking plenty of fluids and electrolytes such as ORS. Consult a doctor before taking any medication.

Headache

Drink plenty of fluids and stay hydrated. Try to be tension free and relaxed. Take adequate sleep and rest. Avoid consumption of alcohol. Apply pain balm if required. Consult your doctor if it is getting worsened.

Nausea And Vomiting

Avoid eating fried and greasy food. Take simple, light, small meals at frequent intervals. Keep yourself hydrated by drinking lots of fluids.

Warning & Precautions

Pregnancy

Contraindicated

DURASALYN PAED LIQUID is not recommended if you are pregnant. Consult your doctor before taking DURASALYN PAED LIQUID.

Breastfeeding

Contraindicated

DURASALYN PAED LIQUID is not recommended for breastfeeding mothers. Consult your doctor before taking DURASALYN PAED LIQUID.

Driving and Using Machines

Use with Caution

DURASALYN PAED LIQUID is not likely to affect your ability to drive and operate machines. Consult your doctor before taking DURASALYN PAED LIQUID.

Allergy

Contraindicated

Do not take DURASALYN PAED LIQUID if you are allergic to bromhexine, choline theophyllinate and salbutamol. Consult your doctor before taking DURASALYN PAED LIQUID.

Lungs

Use with Caution

DURASALYN PAED LIQUID should be taken with caution in patients diagnosed with acute severe asthma, or unstable asthma. Consult your doctor before taking DURASALYN PAED LIQUID.

Heart Disease

Use with Caution

DURASALYN PAED LIQUID should be used with caution in patients with a history of increased blood pressure, irregular heart rate, abnormal pulse rate and angina (chest pain). Consult your doctor before taking DURASALYN PAED LIQUID.

Use In Pediatrics

Safe

DURASALYN PAED LIQUID is marked safe to use in children above 2 years. Consult your doctor before taking DURASALYN PAED LIQUID.

Use In Geriatrics

Safe

DURASALYN PAED LIQUID is marked safe to use in elder people. Consult your doctor before taking DURASALYN PAED LIQUID.

Interactions

A. Drug-Drug interactions:

Before using DURASALYN PAED LIQUID inform your doctor if you are taking the following medicines

• medicines used to manage infections (ex. ampicillin, amoxicillin, erythromycin, clarithromycin, ciprofloxacin, oxytetracycline)
• medicines used to manage psychiatric problems (ex. monoamine oxidase inhibitors such as tranylcypromine, isocarboxacid etc)
• medicines used to manage gastric problems (ex. cimetidine)
• medicines used to manage high blood pressure (ex. atenolol, propranolol, reserpine, methyldopa)
• medicines used for sedation in operation (ex. chloroform, halothane, cyclopropane)
• medicine used to manage asthma (ex. aminophylline, salbutamol)
• medicines used to manage depression (ex. amitriptyline, doxepin etc)
• medicines to manage heart problems(ex .amiodarone, digoxin, quinidine, procainamide etc)
• medicine used to manage hyperactivity (ex. atomoxetine)

Overdosage:

If you or anyone else accidentally took too more of DURASALYN PAED LIQUID, consult your doctor immediately. Symptoms of overdosage include shakiness, increased heart rate, hyperactivity, increased breathing due to acid buildup in the body, decrease in body levels of potassium. Also, nausea, vomiting, and increased blood sugar are seen in children.

Synopsis

More Information

• Keep DURASALYN PAED LIQUID out of reach of children
• Store DURASALYN PAED LIQUID at room temperature

FAQs About DURASALYN PAED LIQUID

Q: What is DURASALYN PAED LIQUID used for?

A: DURASALYN PAED LIQUID is used for the management of asthma, bronchospasm, bronchitis, respiratory diseases, apnea (shortness of breath), and bradycardia (slower heart rate). Bronchospasm is a condition where muscles inside the lungs get tightened. Symptoms include coughing, wheezing, tightness in the chest, and tiredness. Bronchitis is an inflammation of the bronchi (the air passage into the lungs), with symptoms of coughing up thickened mucus and shortness of breath. Consult a doctor before taking DURASALYN PAED LIQUID.

Q: What are the most common side effects of taking DURASALYN PAED LIQUID?

A: The most common side effects of taking DURASALYN PAED LIQUID include vomiting, shakiness, an increased heart rate, a fall in blood pressure, fits, dehydration, increased urine production, and frequent urination. Consult your doctor if any of the symptoms are worsening while taking DURASALYN PAED LIQUID.

Q: How does DURASALYN PAED LIQUID work?

A: DURASALYN PAED LIQUID contains bromhexine, choline, theophylline, and salbutamol. Bromhexine is a mucolytic agent that manages the hypersecretion of mucus. It works by making your mucus thinner and less viscous so that you can get rid of it easily by coughing. Choline theophyllinate and salbutamol are bronchodilators that relax the muscles of the airways in the lungs and make the airways stay open, which makes it easier to breathe. Taking salbutamol increases the heart rate, so it is also used to manage slower heart rates. Theophylline blocks cough reflux by decreasing the excitability of sensory nerves, and thus it helps in the management of cough.

Q: Which conditions should I inform my doctor about before taking DURASALYN PAED LIQUID?

A: Before taking DURASALYN PAED LIQUID, inform your doctor if you are pregnant, breastfeeding, or have diseases like diabetes, unstable asthma, an overactive thyroid gland, an enlarged prostate, low levels of potassium in the blood, a peptic ulcer, etc. to avoid unwanted side effects. Consult your doctor before taking DURASALYN PAED LIQUID.

Q: Can I drive a car while taking DURASALYN PAED LIQUID?

A: DURASALYN PAED LIQUID is not likely to affect your ability to drive. Even though you should not drive if you are feeling shakiness in your body, consult your doctor before taking DURASALYN PAED LIQUID.

References

1. KD Tripathi. Autocoids and related drugs. Essentials of Medical Pharmacology.8th edition. 2019. Page – 238-39, 242-43.

2. Feitoza, Maiane da Silva, Jaqueline Ribas de Melo, Wladimir Musetti Medeiros, Gabriel Grizzo Cucato, Rafael Stelmach, Alberto Cukier, Celso Ricardo Fernandes de Carvalho, and Felipe Augusto Rodrigues Mendes. .Effect of salbutamol on the cardiovascular response in healthy subjects at rest, during physical exercise, and in the recovery phase: a randomized, double-blind, crossover study.Feitoza, Maiane da Silva, Jaqueline Ribas de Melo, Wladimir Musetti Medeiros, Gabriel Grizzo Cucato, Rafael Stelmach, Alberto Cukier, Celso Ricardo Fernandes de Carvalho, and Felipe Augusto Rodrigues Mendes. Effect of salbutamol on the cardiovascular response in healthy subjects at rest, during physical exercise, and in the recovery phase: a randomized, double-blind, crossover study.Motriz: Revista de Educaçao Fisca23 (2017).[Published in 2017] [Accessed on 18th August 2022] https://www.scielo.br/j/motriz/a/mKxwSHkKvgf8xPx5YxCs3cG/?lang=en

3. Dubuis, Eric, Michael A. Wortley, Megan S. Grace, Sarah A. Maher, John J. Adcock, Mark A. Birrell, and Maria G. Belvisi. Theophylline inhibits the cough reflex through a novel mechanism of action. Dubuis, Eric, Michael A. Wortley, Megan S. Grace, Sarah A. Maher, John J. Adcock, Mark A. Birrell, and Maria G. Belvisi. Theophylline inhibits the cough reflex through a novel mechanism of action. Journal of allergy and clinical immunology 133, no. 6 (2014): 1588-1598. [Published in June 2014] [Accessed on 18th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048545/

4. Pinewood Laboratories Ltd. Electronic Medicines Compendium (EMC). [Revised in April 2020][Accessed on 18th August 2022] https://www.medicines.org.uk/emc/files/pil.4557.pdf

5. Opella Healthcare France SAS.Health Products Regulatory Authority (HPRA). [Revised in September 2021] [Accessed on 18th August 2022] https://www.hpra.ie/img/uploaded/swedocuments/4550f813-c219-4e0a-b51a-5e6ed8a8e9f0.pdf

6. GlaxoSmithKline Bangladesh Limited. Salbutamol. [Published on 29th April 2014] [accessed on 18th August 2022] https://gskpro.com/content/dam/global/hcpportal/en_BD/PI/Ventolin_syrup_GDS_22-IPI_06_Clean_Copy_1_03_2019.pdf

7. Union of Arab Pharmacists. Salbutamol. [Revised in June 2015] [Accessed on 18th August 2022] https://www.pharmaline.com.lb/ContentFiles/1645PIL.pdf

8. Malaysian pharmaceuticals. Bromhexine. [Revised on 26th June 2018] [Accessed on 18th August 2022] https://myhealthbox.eu/en/view/3361617/d172a390cd6136aa9014be337a02e83f/leaflet

9. bromhexine+ choline theophylline+ salbutamol . MK medicines. [Accessed on 18th August 2022] https://www.mkmedicine.in/salbutamol-1-mg-bromhexine-2-mg-choline-theophylline-50-mg-syrup.html

Useful Diagnostic Tests

• Blood examination
• Chest x-ray

Author Details

Written By Dr. Dhivakaran R - BDS

Reviewed For Accuracy By Dr. Rajnikant - MBBS, MD (Physiology)

Last updated on 14 Mar 2023 | 01:13 PM(IST)