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Introduction About DUOMATE TRANS CAPSULE
DUOMATE TRANS CAPSULE is a fixed-dose combination of beclomethasone and formoterol which belongs to the group of medicines called anti-asthmatic drugs. It is used in the management of asthma and its symptoms in adults and adolescence patients.
Asthma is a condition which causes swelling and narrowing of the airways resulting in breathing difficulty, extra mucus secretion, breathing difficulty, whistling sound (wheezing) when you breathe out and shortness of breath.
DUOMATE TRANS CAPSULE is not recommended for use in patients allergic to beclomethasone or formoterol. DUOMATE TRANS CAPSULE should be used with caution in patients with heart disease, high blood pressure(hypertension), kidney disease, thyroid disorder, and diabetes. Avoid concomitant use of other antimicrobials and anti-depressants along with DUOMATE TRANS CAPSULE.
DUOMATE TRANS CAPSULE is not recommended for use in pregnant women and breast milk. Consult your doctor before taking DUOMATE TRANS CAPSULE. DUOMATE TRANS CAPSULE should be used with caution in children and adolescents (above 12 years of age). The common side effects of DUOMATE TRANS CAPSULE are sore throat, abnormal voice, headache, and tremors.
Uses Of DUOMATE TRANS CAPSULE
- Management of asthma in adults and adolescence patients
How DUOMATE TRANS CAPSULE Works
DUOMATE TRANS CAPSULE is an anti-asthmatic medicine that works by managing breathing difficulty. It has two medicines namely beclomethasone and formoterol. Beclomethasone a corticosteroid works by blocking the action of cells responsible for causing inflammation in the airways (such as mast cells, eosinophils, basophils, lymphocytes, macrophages, and neutrophils).
Formoterol actively produces relaxation to the smooth muscles in the airway managing constriction of smooth muscles and breathing difficulty. Thus, beclomethasone and formoterol act by reducing inflammation and dilating the airway smooth muscle facilitating normal breathing.
How to use DUOMATE TRANS CAPSULE
Take DUOMATE TRANS CAPSULE as advised by your physician. It is for inhalation use only. Do not miss any dose of DUOMATE TRANS CAPSULE. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Rinse your mouth with water after using DUOMATE TRANS CAPSULE.
Side Effects Of DUOMATE TRANS CAPSULE
Common
- sore throat, abnormal voice
- headache, tremor
- fast heartbeat
Uncommon
- anxiety, nervousness
- restlessness, sleeping trouble
- dizziness, uneven heartbeat
- dry mouth, breathing difficulty
- cough
- muscle spasms, weakness
- itching, rash
Rare
- nausea, low levels of potassium
Stop taking DUOMATE TRANS CAPSULE and contact your doctor immediately if you experience any of the following side effects:
- weakened immune system (immunosuppression) which causes frequent infections such as ear infections, bronchitis, and skin infections symptoms include fever, pain, body pain, chills tiredness, nausea, and vomiting
- reduced adrenal function (adrenal insufficiency), symptoms include
tiredness, nausea, vomiting, lack of energy, low blood pressure, weakness - sudden breathing difficulty immediately after inhaling DUOMATE TRANS CAPSULE
- serious allergic reactions such as rash, swelling of your face, mouth, and tongue, hives, and breathing problems
- serious reactions in the heart such as increased blood pressure, chest pain, irregular heartbeat
- osteoporosis causing bone thinning or weakness
- growth impairment in children and adolescents
- decreased potassium levels (hypokalaemia) symptoms include less oxygen supply to tissues
- eye problems including glaucoma, increased ocular pressure in eyes, cataracts, vision changes
How To Manage Side Effects
Headache
Take some rest, in a quiet place avoid using user mobile phones and other electronic devices for a while. Drink enough amount of Water, dehydration may lead you to develop a headache. If the symptom does not improve, contact your doctor.
Sore Throat
Hot water gargling will help relieve sore throat and manage bacterial infections. Drinking tea will give you relief. Adding food substances like peppermint oil, liquorice root, marshmallow root, fenugreek, and apple cyder vinegar to your daily diet will help you manage sore throat. Avoid contact with sick people. Wash your hands frequently to avoid further infections.
Warning & Precautions
Pregnancy
Use with CautionDUOMATE TRANS CAPSULE should be used with caution in pregnant women. Consult your doctor before taking it.
Breastfeeding
ContraindicatedDUOMATE TRANS CAPSULE is not recommended for use in breastfeeding women. Consult your doctor before taking it.
Alcohol
ContraindicatedConsumption of alcohol is not recommended during management with DUOMATE TRANS CAPSULE.
Kidney
Use with CautionDUOMATE TRANS CAPSULE should be used with caution in patients with kidney disease. Consult your doctor before taking it.
Liver
Use with CautionDUOMATE TRANS CAPSULE should be used with caution in patients with liver diseases. Consult your doctor before taking it.
Allergy
ContraindicatedDo not take DUOMATE TRANS CAPSULE if you are allergic to formoterol or beclomethasone.
Lungs
Use with CautionDUOMATE TRANS CAPSULE should be used with caution in patients with or history of tuberculosis, or other fungal or viral infections in the lungs. Consult your doctor before taking it.
Heart Disease
Use with CautionDUOMATE TRANS CAPSULE should be used with caution in patients with heart diseases such as angina (chest pain), heart attack (myocardial infarction), heart failure, coronary heart disease), arteriosclerosis, high blood pressure, irregular heart rate, rapid pulse rate or other heart diseases. Consult your doctor before taking it.
Use In Pediatrics
ContraindicatedDUOMATE TRANS CAPSULE is not recommended for use in children (below 12 years of age). Consult your doctor before taking it.
Use In Geriatrics
Consult your doctorThere is no proper information regarding the use of DUOMATE TRANS CAPSULE in elderly people. Consult your doctor before taking it.
Others
Before taking DUOMATE TRANS CAPSULE inform your doctor if you:
- have hyperthyroidism (excess production of thyroid hormone)
- have low levels of potassium
- have diabetes
- have a tumour in the adrenal gland (phaeochromocytoma)
Interactions
A. Drug-Drug interactions:
Before taking DUOMATE TRANS CAPSULE, inform your doctor if you are taking any of the following medicine:
- medicines used to manage viral infections Ex. ritonavir, atazanavir, indinavir, nelfinavir, saquinavir and cobicistat which increases the action of ritonavir
- medicines used to manage high blood pressure also known as beta-blockers Ex. propranolol, metoprolol, atenolol
- eye drops used to manage glaucoma (eye disorder) Ex. timolol
- other medicines used to manage breathing difficulty Ex. theophylline
- medicines used to manage uneven heartbeat Ex. quinidine, disopyramide, procainamide
- medicine used to manage mental illness Ex. phenothiazines, disulfiram
- medicines used to manage depression Ex. nefazodone, selegiline, phenelzine, amitriptyline, imipramine
- medicine used to manage bacterial and protozoal infections Ex. furazolidone, metronidazole
- medicine used to manage blood cancer Ex. procarbazine
- hormones used as medicine to induce labour Ex. oxytocin
- inhaled medicines used as anaesthesia before surgeries Ex. nitrous oxide
Overdosage:
If you or anyone else accidentally took more of DUOMATE TRANS CAPSULE, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include headache, tremors, rapid heartbeat, nausea, vomiting, drowsiness, palpitations, excess acid in the body, low potassium levels, high blood glucose and risk of adrenal suppression.
Synopsis
| Drug | : | Beclomethasone, Formoterol |
| Pharmacological Category | : | Anti-asthmatic drugs |
| Therapeutic Indication | : | Asthma |
| Dosage Forms | : | rotacaps, transcaps |
More Information
- Keep DUOMATE TRANS CAPSULE out of reach from children
- Store at room temperature
FAQs About DUOMATE TRANS CAPSULE
Q: How and when should I take DUOMATE TRANS CAPSULE?
A: Take DUOMATE TRANS CAPSULE as advised by your physician. It is for inhalation use only. Do not miss any dose of DUOMATE TRANS CAPSULE. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Q: Can I take more of DUOMATE TRANS CAPSULE to manage my breathing difficulty immediately?
A: No, do not take additional doses of DUOMATE TRANS CAPSULE than recommended doses it may cause serious side effects. If you or anyone else accidentally took more of DUOMATE TRANS CAPSULE, consult your doctor immediately or visit the nearby hospital.
Q: Can I use DUOMATE TRANS CAPSULE along with my other heart medicines?
A: DUOMATE TRANS CAPSULE should be used with caution in patients with heart diseases such as coronary insufficiency, cardiac arrhythmias, and high blood pressure (hypertension). Do not use DUOMATE TRANS CAPSULE without consulting your doctor. DUOMATE TRANS CAPSULE should not be used along with heart medicines such as atenolol and propranolol.
Q: Is it safe to use DUOMATE TRANS CAPSULE on my eyes?
A: No, DUOMATE TRANS CAPSULE is not safe on the eyes. When brought in contact with the eyes it produces complications such as dilation of the pupil, increased ocular pressure, glaucoma, and other eye disorders. DUOMATE TRANS CAPSULE is intended for inhalation purposes only and should be used with caution in patients with narrow-angle glaucoma.
Patients should be informed about the symptoms of acute narrow-angle glaucoma such as eye pain, discomfort, blurred vision, coloured images with red eyes and corneal oedema. You should consult a physician immediately if any of these signs or symptoms develop.
Q: How long will DUOMATE TRANS CAPSULE take to manage my breathing difficulty?
A: DUOMATE TRANS CAPSULE produces bronchodilation within 5 minutes of inhalation which lasts up to a maximum period of 4 hours. DUOMATE TRANS CAPSULE works fast in managing breathing difficulty.
Q: What is DUOMATE TRANS CAPSULE used for?
A: DUOMATE TRANS CAPSULE is a fixed-dose combination of beclomethasone and formoterol which belongs to the group of medicines called anti-asthmatic drugs. It is used in the management of It is used management of asthma and COPD (Chronic Obstructive Pulmonary Disease) and its symptoms in patients who do not respond to other medicines.
Q: How does DUOMATE TRANS CAPSULE work?
A: DUOMATE TRANS CAPSULE is an anti-asthmatic medicine that works by managing breathing difficulty. It has two medicines namely beclomethasone and formoterol. Beclomethasone a corticosteroid works by blocking the action of cells responsible for causing inflammation in the airways (such as mast cells, eosinophils, basophils, lymphocytes, macrophages, and neutrophils).
Formoterol actively produces relaxation to the smooth muscles in the airway managing constriction of smooth muscles and breathing difficulty. Thus, beclomethasone and formoterol act by reducing inflammation and dilating the airway smooth muscle facilitating normal breathing.
Q: Will DUOMATE TRANS CAPSULE cause dependence?
A: No, DUOMATE TRANS CAPSULE will not cause dependence. The condition of asthma or COPD itself requires long-term management. Patients suffering from asthma will develop breathing difficulty more easily than normal adults so it’s always advised to use DUOMATE TRANS CAPSULE irrespective of breathing issues.
Q: What are the side effects of DUOMATE TRANS CAPSULE?
A: The common side effects of DUOMATE TRANS CAPSULE are sore throat, abnormal voice, oral infections, lung infection (pneumonia) and headache. Take some rest, in a quiet place avoid using user mobile phones and other electronic devices for a while. Drink enough amount of Water, dehydration may lead you to develop a headache. Hot water gargle will help relieve sore throat and manage bacterial infections. Drinking tea will give you relief. Adding food substances like peppermint oil, liquorice root, marshmallow root, fenugreek, and apple cyder vinegar to your daily diet will help you manage sore throat. Avoid contact with sick people. Wash your hands frequently to avoid further infections. If the symptom does not improve, contact your doctor.
Q: How should I store DUOMATE TRANS CAPSULE?
A: Keep DUOMATE TRANS CAPSULE out of reach of children. Store at room temperature. Do not use DUOMATE TRANS CAPSULE without consulting your doctor.
References
1. K.D. Tripathi Drugs for Cough and Bronchial Asthma, Essentials of Pharmacology seventh edition Page no: 224,231.
2. Gabriele Nicolini, Nicola Scichilone Beclomethasone/formoterol fixed combination for the management of asthma: patient considerations. October 2008 NCBI, PMC US National Library of Medicine, National Institute of Health [Accessed on 2nd July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621423/
3. Cipla med [Revised in December 2018] [Accessed on 2nd July 2022] https://www.ciplamed.com/content/fullform-rotacaps
4. Chiesi Limited Electronic Medicines Compendium (EMC) [Revised in June 2020] [Accessed on 2nd July 2022] https://www.medicines.org.uk/emc/medicine/29177
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