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Introduction About DROXIB SYRUP
DROXIB SYRUP contains Cefadroxil which belongs to the group of medicines called Cephalosporin antibiotics. It is used in children to manage bacterial infections of the throat and upper part of the respiratory tract, skin and soft tissues, and the urinary tract. A bacterial infection can be defined as a proliferation of various harmful strains of bacteria in the body. They can affect any part(s) of the body including the respiratory tract, urinary tract, eyes, ears, skin, soft tissue, or bones. DROXIB SYRUP is typically used in young children who weigh less than 40 kg.
DROXIB SYRUP must be taken with meals to avoid unwanted gastrointestinal side effects. Your doctor will decide the suitable dose for your child depending upon their age, body weight and severity of the infection.
Make sure that your child does not miss a dose of DROXIB SYRUP, as it may lead to growth of harmful bacteria within their body which cannot be further controlled by DROXIB SYRUP.
DROXIB SYRUP should not be used if your child is allergic to penicillin antibiotics (such as amoxicillin, ampicillin) or has severe kidney impairment. It is also important to inform your doctor if your child is going to undergo any blood test or urine test while undergoing therapy with DROXIB SYRUP.
The most common side effects of taking DROXIB SYRUP are nausea, vomiting, stomach pain and diarrhea. These side effects may probably reduce if DROXIB SYRUP is taken along with meals. However, consult your doctor if any of these side effect bothers your child.
Uses Of DROXIB SYRUP
It is indicated for the management of the following bacterial infections in young children (who weigh less than 40 kg):
- throat infections (such as pharyngitis and tonsillitis)
- respiratory infections (such as pneumonia)
- urinary tract infections (such as cystitis or pyelonephritis)
- skin and soft tissue infections (such as abscesses, furunculosis, impetigo, erysipelas, pyoderma, lymphadenitis)
How DROXIB SYRUP Works
DROXIB SYRUP kills harmful bacteria where cefadroxil binds to the bacterial cell and interferes with the formation of bacterial cell wall. As a result, it weakens the bacterial cells and causing lysis of the bacteria.
How to use DROXIB SYRUP
Take DROXIB SYRUP as advised by your physician. Shake the bottle well to loosen the contents. Reconstitute the medicine with required amount of sterile water given along with the medicine. Shake the contents vigorously to obtain a uniform mixture. Children must consume the medicine immediately after reconstitution. DROXIB SYRUP must be taken with meals to avoid unwanted gastrointestinal side effects.
Your doctor will decide the suitable dose and duration of therapy for your child depending upon their age, body weight and severity of infection. It is important to take the full course of DROXIB SYRUP without any interruption. Therefore, make sure that your child does not miss a dose of DROXIB SYRUP, as it may lead to growth of harmful bacteria within their body which cannot be further controlled by DROXIB SYRUP.
Side Effects Of DROXIB SYRUP
Common
- nausea, vomiting
- diarrhoea, indigestion, stomach pain
- skin rash with itching
- swollen sore tongue
Uncommon
- vaginal fungal infections or ‘thrush’
Rare
- unexplained bruising or bleeding, which may be due to reduced platelets
- fever, feeling weak, generally unwell, muscle pain with or without swollen glands (serum sickness)
- joint pain
Contact your doctor immediately if your child experiences any of the following side effects:
- signs of infections (such as fever, general weakness, sore throat or mouth and problems in passing urine)
- severe allergic reaction (such as skin rash, itching, swelling of the face, tongue or pharynx, difficulty to swallow or breathe and chest tightness)
- signs of kidney problems (such as bloody or cloudy urine, scanty or no urine accompanied with lower back pain)
- inflammation of the colon (colitis) with bloody diarrhea
- severe skin reactions causing blistering of the skin, mouth, eyes, and genitals
- signs of low RBC count (such as yellow or pale skin, weakness, or breathlessness)
How To Manage Side Effects
Nausea and Vomiting:
Make sure that your child takes DROXIB SYRUP with or just after meals. Eating a simple meal can be beneficial. Avoid giving them oil rich or spicy foods. Consult your doctor if nausea worsens in your child.
Diarrhoea:
Make sure that your child drinks plenty to fluids, such as water or fruit juices to keep themselves hydrated. Consuming ORS can also be beneficial. Do not self-manage diarrhea on your own. Consult your doctor if your child experience severe diarrhea with blood stains.
Warning & Precautions
Pregnancy
DROXIB SYRUP is intended for use only in the children.
Breastfeeding
DROXIB SYRUP is intended for use only in the children.
Driving and Using Machines
DROXIB SYRUP may make your child feel dizzy. Therefore, do not let your child to ride bicycle on their own or play with heavy objects. Keep them away from playing outdoors as well.
Kidney
DROXIB SYRUP is not recommended for use in children who have severe kidney problems, It should be used with caution in those undergoing dialysis. Therefore, consult your doctor for advice.
Liver
DROXIB SYRUP should be used with caution if your child has any liver problems. Therefore, consult your doctor for advice.
Allergy
Talk to your doctor if your child is allergic to Cefadroxil or to any other penicillin antibiotics (Ex. amoxicillin).
Others
Before using DROXIB SYRUP in children, inform your doctor if they:
- are going to have any blood test (such as Coombs test) or urine test
- have a history of stomach problems
Use in pediatrics:
DROXIB SYRUP should be used with caution in infants, children, and adolescents (below 18 years). Therefore, consult your doctor for advice.
Use in geriatrics:
DROXIB SYRUP is intended for use only in the children.
Interactions
A. Drug-Drug interactions:
Inform your doctor if your child is taking any of the following medicines such as:
- medicines used for blood thinning (Ex. heparin and warfarin)
- medicines used to manage gout (Ex. probenecid)
- medicines used to lower elevated blood cholesterol levels (Ex. cholestyramine)
- antibiotics used to manage bacterial infection (Ex. erythromycin, sulfamethoxazole/trimethoprim, chloramphenicol, polymyxin B, vancomycin, colistin, gentamicin)
- diuretics (used to increase urine output) Ex. furosemide
Overdosage:
If your child accidentally took more DROXIB SYRUP consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage might include allergic reaction causing dizziness or breathing difficulties, low blood pressure, abnormal heartbeat, nausea, vomiting, diarrhea, skin eruptions or muscular contractions.
Synopsis
| Drug | : |
Cefadroxil |
| Pharmacological Category | : |
Cephalosporins |
| Therapeutic Indication | : |
Bacterial infections |
| Dosage Forms | : |
Tablet, Capsule, Drops, Dispersible tablet, Oral Drops, Syrup, Suspension, Dry Syrup and Dry Suspension |
More Information
- Keep DROXIB SYRUP out of reach of children
- Store DROXIB SYRUP at room temperature
- After reconstitution, the mixture must be stored in a refrigerator (2-8°C)
- Use the prepared mixture within 14 days of reconstitution
FAQs About DROXIB SYRUP
What is DROXIB SYRUP used for?
DROXIB SYRUP is an antibiotic. It is used to manage bacterial infections of the throat and upper part of the respiratory tract, skin and soft tissues, and the urinary tract.
When should I take DROXIB SYRUP?
DROXIB SYRUP is taken preferably after meals. If you are confused or doubtful regarding the use of DROXIB SYRUP consult your doctor for advice.
What kind of infections that DROXIB SYRUP can manage?
DROXIB SYRUP is an antibiotic. It is used to manage infections caused by bacteria. It kills harmful bacteria by binding to the bacterial cell and by interfering with cell wall synthesis. It can manage bacterial infections of the throat and upper part of the respiratory tract, skin and soft tissues, and the urinary tract.
Who should not take DROXIB SYRUP?
DROXIB SYRUP should not be used if your child is allergic to penicillin antibiotics (such as amoxicillin, ampicillin) or has severe kidney impairment. It should be used with caution in children with liver problems.
Is DROXIB SYRUP a steroid?
No. DROXIB SYRUP is an antibiotic and not a steroid medicine.
Can DROXIB SYRUP manage viral infections?
No. DROXIB SYRUP cannot manage viral infections. It manages only bacterial infections of upper respiratory tract, urinary tract, and skin infections. It acts by killing the susceptible bacteria which are responsible for causing infections, and therefore not effective against any viral infections.
Can DROXIB SYRUP cause diarrhea?
Yes. DROXIB SYRUP may cause diarrhea in some children. Make sure that your child drinks plenty to fluids, such as water or fruit juices to keep themselves hydrated. Consuming ORS can also be beneficial. Do not self-manage diarrhea on your own. Consult your doctor if your child experience severe diarrhea with blood stains.
Can DROXIB SYRUP cause fever?
DROXIB SYRUP may rarely cause a mild fever in some children. However, if your child experiences heavy fever accompanied with general weakness, sore throat or mouth and problems in passing urine consult your doctor immediately.
Can I stop giving DROXIB SYRUP to my child once the symptoms subside?
No. It is important to take the full course of DROXIB SYRUP without any interruption. Therefore, make sure that your child does not miss a dose of DROXIB SYRUP, as it may lead to growth of harmful bacteria within their body which cannot be further controlled by DROXIB SYRUP.
Will taking a higher dose of DROXIB SYRUP be more effective?
No. Taking a higher dose of DROXIB SYRUP can do more harm rather than being beneficial. Always take the dose prescribed by your physician. Your doctor will decide the suitable dose for your child depending upon their age, body weight and severity of the infection. Taking a high dose of this medicine, may cause growth of harmful bacteria within their body which cannot be further controlled by DROXIB SYRUP. It may also cause unwanted side effects like nausea, vomiting, diarrhea, dizziness or breathing difficulties and low blood pressure.
How to take [GBNKEYWORD]?
Take DROXIB SYRUP as advised by your physician. Shake the bottle well to loosen the contents. Reconstitute the medicine with required amount of sterile water given along with the medicine. Shake the contents vigorously to obtain a uniform mixture. Children must consume the medicine immediately after reconstitution. Your doctor will decide the suitable dose and duration of therapy for your child depending upon their age, body weight and severity of infection.
How to store DROXIB SYRUP?
Keep DROXIB SYRUP out of reach of children. Before reconstitution, it can be stored at room temperature. After reconstitution, it must be stored in a refrigerator. The prepared mixture must be used within 14 days of reconstitution.
References
1. KD. Tripathi. Antimicrobial drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 726.
2. M Fujita, T Kuronuma, R Aoyama, K Nagata, Y Izumi. Clinical experience with cefadroxil dry syrup in pediatric infections (author's transl). NIH. National Library of Medicine. National Center of Biotechnology Information. Pubmed.gov. February 1981. [Accessed on 14th June 2022] https://pubmed.ncbi.nlm.nih.gov/7253192
3. McDermott Laboratries Ltd. [Revised in March 2019] [Accessed on 11th May 2022] https://docetp.mpa.se/LMF/Cefadroxil%20Mylan%20capsule%20hard,%20film-coated%20tablet,%20oral%20suspension%20ENG%20PL_09001be680190988.pdf
4. Alkaloid. [Revised in Sept 2016] [Accessed on 11th May 2022] https://mhraproductsprod.blob.core.windows.net/docs/88385952618972d5c021781d323996724a4bae8d
5. Lupin Pharmaceuticals, Inc. [Revised in May 2014] [Accessed on 11th May 2022] https://www.lupin.com/US/pdf/14/Cefadroxil%20OS_PI_4.30.14.pdf
6. Cipla Ltd. CEFADUR Tablet (Cefadroxil). Ciplamed.com. [Revised in December 2013] [Accessed on 11th May 2022] https://www.ciplamed.com/content/cefadur-tablet
Useful Diagnostic Tests
- Complete Blood Count
- Peripheral Smear Examination
- Kidney Function Test
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