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Introduction About DROTIN TABLET

Drotin Tablet is an antispasmodic medicine prescribed to help relieve pain caused by spasms of smooth muscles. It is commonly used to manage menstrual cramps and abdominal pain associated with muscle contractions in the digestive, biliary, and urinary systems.

By relaxing smooth muscles, Drotin Tablet may help reduce discomfort linked to conditions such as gastrointestinal colic, biliary stone-related pain, and kidney stone-associated spasms. Doctors may recommend this medicine for short-term relief from spasm-related pain, as advised by a healthcare professional.

Drotin Tablet may be taken with or without food. For best results, it is advisable to take it at a fixed time each day. The dosage and frequency are determined by the condition being managed and should be decided by your doctor. Continue taking this medicine for the full duration prescribed, even if your symptoms improve, unless advised otherwise by a healthcare professional.

Common side effects of Drotin Tablet include nausea, vomiting, dry mouth, dizziness and headache. These effects are usually mild, but if they persist or become troublesome, consult your doctor for advice on how to manage them. In some cases, this medicine may cause dizziness due to low blood pressure. If you experience dizziness, avoid driving or operating machinery and take appropriate precautions.

Before starting Drotin Tablet, inform your doctor if you have a history of heart disease, blood pressure problems, or liver or kidney disorders. It is also important to share details of any other medicines you are currently taking, as some may interact with this medicine or affect how it works. Your doctor may monitor your blood pressure regularly during management to ensure safe use.

Uses Of DROTIN TABLET

Drotin Tablet is usually prescribed by doctors to provide short-term relief from pain due to smooth muscle spasms, such as:

Menstrual cramps (period pain)
Abdominal pain due to gastrointestinal spasms
Pain associated with kidney stones
Discomfort caused by biliary tract spasms

Benefits of DROTIN TABLET

01) Helps Manage Abdominal Spasm-Related Discomfort
Provides relief from abdominal pain caused by involuntary muscle contractions in the digestive, urinary, and biliary systems.

02) Used for Stomach Cramps and Gastrointestinal Pain
Eases cramp-like abdominal pain and colic associated with gastrointestinal muscle spasms.

03) Supports Comfort During Menstrual-Related Cramps
Relieves uterine muscle cramps, helping to reduce discomfort during menstruation.

04) Recommended for Pain Linked to Smooth Muscle Spasms
Doctors may prescribe it for short-term relief from pain caused by spasms in smooth muscles.

05) May Assist in Reducing Spasmodic Abdominal Pain
Targets sudden or recurring abdominal spasms to provide relief and improve daily comfort.

06) Used in Conditions Associated with Muscle Tightness
Helps relax muscles in conditions where involuntary contractions cause discomfort.

07) Provides Quick Pain Relief Without Sedation
Acts efficiently to reduce pain while keeping the patient alert and active.

08) Non-Narcotic and Non-Addictive
Safe for use without the risk of dependency or addiction.

09) Does Not Affect Cardiovascular or Respiratory Systems
Can be used without impacting heart or lung function in most patients.

10) Suitable for Long-Term Use Under Medical Supervision
Can be safely continued for extended periods when prescribed and monitored by a healthcare professional.

How DROTIN TABLET Works

01) Relaxes Smooth Muscles in the Body
Drotin Tablet helps relax involuntary smooth muscles, reducing spasms in the digestive, urinary, and biliary systems to ease discomfort.

02) Supports Muscle Relaxation by Acting on Muscle Fibres
It works directly on smooth muscle fibers, relieving cramps and tension caused by sudden or prolonged contractions.

03) Influences Enzyme Activity Linked to Muscle Tightness
The medicine may help regulate enzyme activity involved in muscle contraction, supporting normal muscle function and reducing spasms.

04) Helps Reduce Muscle Contraction Without Affecting Normal Movement
Targets abnormal muscle contractions while preserving normal movement, providing pain relief without limiting daily activity.

05) Works Directly on Smooth Muscle Cells
Acts on smooth muscle cells to control involuntary spasms, offering targeted relief from abdominal, biliary, or urinary tract discomfort.

How to use DROTIN TABLET

01) Recommended Dosage as Advised by a Doctor
Take Drotin Tablet exactly as prescribed by your doctor. The dose may vary depending on the condition being managed and your overall health.

02) How to Take Drotin Tablet
Swallow the tablet whole with water. It can be taken with or without food, based on your comfort and doctor’s instructions.

03) Administration Guidelines for Drotaverine Tablets
Follow the instructions provided by your healthcare professional carefully. Do not exceed the recommended dose.

04) Dosage Schedule Based on Medical Advice
Take the medicine at the same time each day if prescribed for multiple doses. Your doctor will guide the frequency and duration of management.

05) Oral Intake Instructions for Drotin Tablet
Ensure the tablet is taken orally with adequate water. Continue the medication for the full duration advised, even if your symptoms improve, unless your doctor instructs otherwise.

Side Effects Of DROTIN TABLET

Common:

Nausea
Vomiting
Dry mouth
Dizziness
Headache

When to consult your doctor?

Severe allergic reactions symptoms such as rash, itching, swelling of the face, lips, or throat, or difficulty breathing
Persistent dizziness or fainting
Rapid or irregular heartbeat
Unusual swelling in hands, feet, or ankles

How To Manage Side Effects

Headache

Stay Hydrated: Drink plenty of water throughout the day to help ease headache symptoms.
Rest in a Quiet Environment: Minimize noise and bright lights by resting in a calm, dark room.
Use Over-the-Counter Pain Relief: Consult your doctor about using mild pain relievers like acetaminophen to alleviate headaches.
Avoid Stressful Activities: Limit activities that increase stress or physical exertion when experiencing headaches.
Seek Medical Advice: Contact your healthcare provider if headaches become severe, persistent, or are accompanied by other symptoms.

Nausea And Vomiting

Stay Hydrated: Sip fluids slowly, such as water, ginger tea, or clear soups to support hydration and reduce discomfort.
Eat Small, Bland Meals: Choose light foods like crackers, toast, or plain rice to minimize stomach irritation.
Avoid Strong Odors and Spicy Foods: These can worsen feelings of nausea and should be limited during symptoms.
Rest and Relaxation: Rest in a comfortable position and avoid sudden movements to calm the digestive system.
Seek Medical Advice: Consult a healthcare provider promptly if nausea is severe, persistent, or accompanied by vomiting.

Warning & Precautions

Pregnancy

Use with Caution

Animal and human studies have not shown harmful effects on the developing fetus. However, caution is advised as the safety of Drotin Tablet during pregnancy is not fully established. Pregnant women should use this medicine only under medical supervision. Always consult your doctor before taking Drotin Tablet while pregnant to ensure it is safe for both you and your baby.

Breastfeeding

Contraindicated

There is limited clinical information available on the use of Drotaverine in breastfeeding women. Due to the lack of sufficient safety data, Drotaverine is not recommended during lactation. Breastfeeding mothers should consult a healthcare professional before using this medicine.

Driving and Using Machines

Use with Caution

Drotin Tablet generally does not affect the ability to drive or operate machines when taken at the recommended dose. However, if you experience side effects such as dizziness or vertigo avoid driving or using heavy or moving machinery. If your ability to perform these activities is affected after taking this medicine, assess your condition carefully and refrain from engaging in potentially hazardous tasks. Always consult your doctor if you are unsure.

Kidney

Consult your doctor

Drotin Tablet is not recommended for patients with severe kidney disease. Patients with mild to moderate kidney problems should use this medicine with caution and only under medical supervision. Consult your doctor before taking Drotin Tablet if you have any kidney-related condition.

Liver

Consult your doctor

Drotin Tablet is not recommended for patients with severe kidney or liver disease. Patients with mild to moderate kidney or liver problems should use this medicine with caution and only under medical supervision. Consult your doctor before taking Drotin Tablet if you have any kidney or liver-related condition.

Allergy

Contraindicated

Do not take Drotin Tablet if you are allergic to Drotaverine or Mefenamic acid or Aspirin or Other anti-inflammatory agents or any other ingredient in the formulation. Seek immediate medical attention if signs of an allergic reaction occur.

Lungs

Contraindicated

Drotin Tablet is not recommended for patients with a history of allergic rhinitis or urticaria (hives), or asthma. Inform your doctor about any existing allergy-related conditions before starting this medicine.

Heart Disease

Consult your doctor

Drotin Tablet is not recommended for patients with heart failure or cardiac insufficiency (low output syndrome), or cardiogenic shock. Patients with other forms of cardiac dysfunction or hypotension should use it with caution under medical supervision. Consult your doctor before taking this medicine if you have any heart-related condition.

Use In Pediatrics

Consult your doctor

Drotin Tablet can be used in children and adolescents only if prescribed by a doctor. It is not suitable for infants and neonates under 1 year of age. Consult your paediatrician before giving it.

Use In Geriatrics

Use with Caution

Drotin Tablet should be used with caution in elderly patients, especially those with pre-existing medical conditions. Consult your doctor before taking this medicine if you are an older adult with any health concerns.

Who should not take DROTIN TABLET

Drotin Tablet is not recommended for use in patients suffering from:

Ulceration or chronic inflammation of the upper or lower GI tract Porphyria

Drug - Drug interaction

1. Ketoconazole (Antifungal medicine)

Interaction: Ketoconazole may alter how Drotin is processed in the body.
Effects: Could increase Drotin blood levels, potentially causing dizziness, low blood pressure, or other side effects.
Management: Inform your doctor if any side effects occur. Dose adjustments may be needed.

2. Rifampicin (Antibiotic medicine)

Interaction: Rifampicin may reduce Drotin’s effectiveness by increasing its breakdown.
Effects: Could make Drotin less effective in relieving muscle spasms or pain.
Management: Your doctor may monitor your response or adjust the dose.

3. Antihypertensive medicines (e.g., Beta-blockers, ACE inhibitors)

Interaction: Drotin may enhance the blood pressure-lowering effects of these medicines.
Effects: Could cause dizziness, lightheadedness, or low blood pressure.
Management: Take precautions when standing up quickly and inform your doctor about any side effects.

4. Other spasmolytics

Interaction: Using Drotin with other spasmolytics may increase overall antispasmodic effect.
Effects: Could lead to excessive muscle relaxation or dizziness.
Management: Inform your doctor before combining these medicines.

5. Tricyclic antidepressants

Interaction: May enhance Drotin’s sedative or hypotensive effects.
Effects: Could cause dizziness, drowsiness, or low blood pressure.
Management: Monitor symptoms and consult your doctor if side effects appear.

6. Quinidine and Novocainamide (Antiarrhythmic agents)

Interaction: May affect Drotin metabolism or increase cardiac effects.
Effects: Could increase the risk of abnormal heart rhythms or low blood pressure.
Management: Use only under strict medical supervision.

7. Morphine (Painkiller)

Interaction: May enhance sedative or hypotensive effects of Drotin.
Effects: Could cause dizziness, drowsiness, or low blood pressure.
Management: Avoid driving or operating machinery and inform your doctor about side effects.

8. Antiparkinsonian medicines (e.g., Levodopa)

Interaction: Drotin may affect how these medicines work in the body.
Effects: Could alter symptom control of Parkinson’s disease.
Management: Dose adjustments may be required under doctor supervision.

9. Analgesics, Antimuscarinics, or Benzodiazepines

Interaction: Combining with Drotin may increase sedative or muscle-relaxant effects.
Effects: Could lead to dizziness, drowsiness, or excessive muscle relaxation.
Management: Monitor for side effects and inform your doctor if symptoms occur.

Synopsis

Drug	:	Drotaverine
Pharmacological Category	:	Antispasmodics
Therapeutic Indication	:	Relief from smooth muscle cramps
Dosage Forms	:	Tablet, Suspension, Injection

More Information

01) Why is all abdominal pain different? How does cramp-like pain differ from other types of discomfort, and how can DROTIN Tablet help?

Understanding Different Types of Abdominal Pain:
Not all abdominal pain feels the same. Some pain is cramp-like or spasmodic, caused by sudden muscle contractions in the stomach or intestines, while other discomfort may feel dull, constant, or pressure-like, often linked to infections, inflammation, or other conditions.

Why Awareness Matters:
Many people may confuse cramp-like pain with general stomach discomfort, which can lead to delayed relief or inappropriate self-management. Understanding the type of pain is important for effective symptom management.

Role of DROTIN Tablet in Symptom Relief:

DROTIN Tablet is an antispasmodic that works by relaxing smooth muscles, providing targeted relief from cramp-like abdominal pain. It specifically helps with muscle spasm-related discomfort, supporting better day-to-day comfort under medical supervision.

Why Proper Use is Important:
Using DROTIN Tablet as prescribed by a doctor is essential for safe and effective relief. Managing cramp-like pain may also include hydration, diet modifications, and avoiding triggers. Consistent and guided use helps maintain effective symptom control.

Important Safety Note:

Always take DROTIN Tablet under healthcare guidance and report any persistent or worsening abdominal pain. It is meant for muscle spasm relief and is not a management for all types of abdominal pain.

FAQs About DROTIN TABLET

Q: What is DROTIN Tablet?

A: DROTIN Tablet is a prescription medicine that belongs to the antispasmodic category. It is commonly prescribed for the relief of smooth muscle cramps and cramp-like abdominal pain, under medical supervision.

Q: How does DROTIN Tablet work?

A: DROTIN Tablet works by relaxing the smooth muscles of the stomach, intestines, and other organs, helping to relieve cramp-like pain and spasms.

Q: Who can take DROTIN Tablet?

A: DROTIN Tablet can be taken by children, adolescents, and adults under a doctor’s prescription. It is not suitable for infants under 1 year. Elderly patients or those with kidney, liver, or heart conditions should use it with caution.

Q: Can DROTIN Tablet be used for all types of abdominal pain?

A: No. DROTIN Tablet is specifically for muscle spasm-related abdominal pain. Dull, constant, or pressure-like pain may need different management, so consult your doctor for proper evaluation.

Q: Can this medicine be taken with food?

A: Yes, DROTIN Tablet can be taken with or without food. Taking it with food may help reduce stomach irritation in sensitive individuals.

Q: How quickly does DROTIN Tablet start to work?

A: DROTIN Tablet usually starts to relieve cramp-like abdominal pain within 30–60 minutes. The exact time may vary depending on the severity of the symptoms and individual response.

Q: Can this be used during special health conditions?

A: Patients with kidney, liver, or heart problems, or those who are elderly or pregnant, should use DROTIN Tablet with caution and only under medical supervision. Always consult your doctor if you have any existing health conditions before taking this medicine.

Q: Are there any safety precautions?

A: Avoid using DROTIN Tablet if you have severe kidney or liver disease, heart failure, or allergy to its ingredients. Use caution while driving or operating machinery if you feel dizzy after taking it. Always follow your doctor’s guidance.

References

1.KD. Tripathi. Anticholinergic Drugs and Drugs Acting on Autonomic Ganglia. Essentials of Medical Pharmacology. Eighth edition. 2019. Page 129.

2.I Romics 1, D L Molnár, G Timberg, B Mrklic, B Jelakovic, G Köszegi, G Blaskó. The effect of drotaverine hydrochloride in acute colicky pain caused by renal and ureteric stones. NIH National Library of Medicine. National Centre for Biotechnology Information. PubMed. July 2003. [Accessed on 10th Feb 2026]

3.Piotr Eder, Piotr Kowalski, Agnieszka Mastalerz-Migas, Barbara Skrzydlo-Radomanska, Wojciech Cichy, Katarzyna Proga. Self-Medication with Drotaverine among Patients with Common Abdominal Symptoms and Treatment Efficacy from the Perspectives of Patients and General Practitioners—An Observational, Retrospective, Cross-Sectional Study Using Real-World Data. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. 1 June 2022. [Accessed on 10th Feb 2026]