DOMI DT Dispersible Tablet 10's

Introduction About DOMI DT DISPERSIBLE TABLET

DOMI DT DISPERSIBLE TABLET contains Domperidone commonly used to manage in post-operative vomiting, drug-induced nausea and vomiting, vomiting due to radiation and anticancer drugs and in acute vomiting due to a variety of causes such as fever, gastritis, pancreatitis, uremia and hepatitis.

DOMI DT DISPERSIBLE TABLET is also indicated in various types of dyspepsia such as postprandial, that associated with peptic ulcer and also in reflux oesophagitis as well as gastritis. It works by blocking dopamine receptors and improving digestion.

DOMI DT DISPERSIBLE TABLET helps in relieving nausea and vomiting, improves digestion by enhancing stomach movement and also may help with bloating and discomfort.

Take DOMI DT DISPERSIBLE TABLET as directed by your doctor. Usually taken before meals. Do not exceed the prescribed dose.

Avoid using DOMI DT DISPERSIBLE TABLET if you have liver disease or a history of heart issues. Consult a doctor if pregnant or breastfeeding.

The possible side effects of DOMI DT DISPERSIBLE TABLET are dry mouth, dizziness and abdominal cramps. Consult your doctor if any of the above side effects worsen or persists for a longer duration.

Uses Of DOMI DT DISPERSIBLE TABLET

It is used to manage:

• post-operative vomiting
• drug-induced nausea and vomiting
• vomiting due to radiation and anticancer drugs
• acute vomiting due to a variety of causes such as fever, gastritis, pancreatitis, uremia and hepatitis
• various types of dyspepsia such as postprandial, that associated with peptic ulcer and also in reflux oesophagitis as well as gastritis

Benefits of DOMI DT DISPERSIBLE TABLET

1. Relieves nausea and vomiting:

• Effectively helps manage nausea and vomiting caused by indigestion, gastritis, motion sickness, and certain medications
• Works by blocking dopamine receptors in the brain, reducing the urge to vomit

2. Improves digestion by enhancing stomach movement:

• Stimulates gastric motility, helping food move smoothly through the stomach and intestines
• Beneficial for individuals suffering from acid reflux, delayed digestion, and sluggish bowel movements

3. May help with bloating and discomfort:

• Helps relieve gas, bloating, and feelings of fullness after meals
• Supports smooth digestion and stomach emptying, managing discomfort from indigestion

How DOMI DT DISPERSIBLE TABLET Works

1. How quickly does DOMI DT DISPERSIBLE TABLET work?

• DOMI DT DISPERSIBLE TABLET typically starts working within 30 to 60 minutes after ingestion
• It provides rapid relief from nausea, vomiting, and bloating by improving stomach movement and reducing discomfort

2. How effective is DOMI DT DISPERSIBLE TABLET for nausea and vomiting?

• DOMI DT DISPERSIBLE TABLET is clinically proven to be effective in managing nausea and vomiting caused by indigestion and acid reflux, gastritis and food poisoning, motion sickness and certain medications (e.g., chemotherapy, painkillers)

How to use DOMI DT DISPERSIBLE TABLET

DOMI DT DISPERSIBLE TABLET is a prescription medicine which needs to be taken under medical supervision. Always consult your doctor or pharmacist if you have any questions or concerns about taking this medication.

DOMI DT DISPERSIBLE TABLET dosage instructions:

• Take DOMI DT DISPERSIBLE TABLET as directed by your doctor. Usually taken before meals
• Children (weighing more than 35 kg): As prescribed by a doctor
• Maximum Dose: Do not exceed 30 mg per day unless advised by a healthcare provider

How to take DOMI DT DISPERSIBLE TABLET:

• Take 15 to 30 minutes before meals for better absorption
• Swallow the tablet whole with a glass of water, do not crush or chew

Can DOMI DT DISPERSIBLE TABLETbe taken on an empty stomach?

• DOMI DT DISPERSIBLE TABLET is best taken on an empty stomach, preferably 15 to 30 minutes before meals
• Better absorption - Taking it before meals allows the medication to work faster and more effectively
• Enhances stomach movement - Helps food pass through the digestive tract smoothly, reducing nausea and bloating
• Manages Vomiting - Taking it in advance helps control nausea before eating

How to take DOMI DT DISPERSIBLE TABLET for best results?

• Take it on an empty stomach - consume 15 to 30 minutes before meals for better absorption and faster relief
• Follow the prescribed dosage - usually one tablet (10mg), up to three times a day, or as directed by your doctor
• Swallow whole with water - do not crush or chew the tablet, as this may affect its effectiveness
• Avoid alcohol and certain medications - alcohol and some drugs (like antifungals, antibiotics, or acid reducers) may interfere with its action
• Stay consistent - For chronic conditions like acid reflux or bloating, take it at the same time daily for optimal results

What if I forgot to take DOMI DT DISPERSIBLE TABLET

• Take the missed dose as soon as you remember
• If it is almost time for the next dose, skip the missed dose, do not double dose for the missed dose

Overdose

Symptoms of DOMI DT DISPERSIBLE TABLET Overdose:

• drowsiness or confusion
• irregular heartbeat (arrhythmia or palpitations)
• dizziness or fainting
• severe restlessness or agitation
• uncontrolled muscle movements (twitching or tremors)

What to do in case of an overdose?

• Seek immediate medical attention – Call your doctor or visit the nearest hospital
• Do not induce vomiting unless instructed by a healthcare provider
• Monitor for serious symptoms like difficulty breathing or chest pain
• Take the medicine packaging with you to the hospital for reference

Side Effects Of DOMI DT DISPERSIBLE TABLET

Common:

• dry mouth
• dizziness
• abdominal cramps

When to consult a doctor?

• swelling of the hands, feet, ankle, face, lips and throat which may cause difficulty in swallowing or breathing
• itchy lumpy rash (hives), nettle rash (urticaria)
• uncontrolled movements, which include irregular movements of eyes, an unusual move of the tongue, abnormal posture (Ex. twisted neck, trembling and muscle stiffness)
• have a fast unusual heartbeat
• seizures

How To Manage Side Effects

Dizziness Or Drowsiness

• Take adequate sleep. Do not involve in rigorous activities
• Do not interfere with your sleep cycle

Dry Mouth

• Dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva
• Sip water at regular intervals of time
• Do not use mouthwashes that contain alcohol because they can be drying

Stomach Pain

• Apply Heat: Use a warm compress or heating pad on your stomach to relax muscles
• Drink Herbal Teas: Ginger, peppermint, or chamomile tea can soothe digestion
• Gentle Massage: Lightly rub your abdomen in a circular motion to relieve tightness

Warning & Precautions

Pregnancy

Monitoring required

Pregnant women should use DOMI DT DISPERSIBLE TABLET only if necessary under medical supervision. It crosses the placenta, and while no major birth defects have been reported, studies on its safety in pregnancy are limited. Doctors may prescribe it only if the benefits outweigh the risks, particularly in cases of severe nausea and vomiting (morning sickness or hyperemesis gravidarum).

Breastfeeding

Monitoring required

Breastfeeding mothers should discuss the risks with their doctor. If prescribed while breastfeeding, monitor the baby for any unusual symptoms and seek pediatric advice if needed. DOMI DT DISPERSIBLE TABLET passes into breast milk in small amounts, so caution is advised. It is sometimes prescribed to increase breast milk production (off-label use), but its safety for this purpose is debated. Potential risks for the baby may cause drowsiness, irritability, or digestive issues in infants, long-term effects on breastfed babies are not well studied.

Driving and Using Machines

Use with Caution

DOMI DT DISPERSIBLE TABLET does not affect the ability to drive or use machines. Yet do not drive or operate any machines if you feel dizzy after taking the medicine.

Kidney

Use with Caution

DOMI DT DISPERSIBLE TABLET should be taken with caution in patients with kidney problems such as kidney impairment or kidney failure.

Liver

Use with Caution

DOMI DT DISPERSIBLE TABLET may be used with dose adjustments, as advised by a doctor in patients with mild to moderate liver disease. DOMI DT DISPERSIBLE TABLET is metabolized in the liver, and impaired liver function can lead to higher drug accumulation, increasing the risk of side effects in patients with severe liver disease (cirrhosis, hepatic impairment).

Allergy

Contraindicated

Do not take DOMI DT DISPERSIBLE TABLET if you are allergic to Domperidone or any other ingredients of this medicine.

Heart Disease

Contraindicated

DOMI DT DISPERSIBLE TABLET is not recommended in patients suffering from heart problems such as prolonged QT corrected interval or heart failure.

Use In Pediatrics

Consult your doctor

DOMI DT DISPERSIBLE TABLET is not recommended for use in children and adolescents below 12 years of age or weighing less than 35 kgs. Consult with your child’s doctor before giving this medicine to your child.

Use In Geriatrics

Use with Caution

DOMI DT DISPERSIBLE TABLET should be used with caution for use over 60 years of age, as this medicine may associated with an increased risk of heart rhythm disorder and cardiac arrest.

Who should not take [GBNKEYWORD

DOMI DT DISPERSIBLE TABLET is not recommended for use if you have:

• tumor in the pituitary gland (prolactinoma)
• history of blockage or tear in the intestine
• hypokalemia (low level of potassium)
• hyperkalemia (high level of potassium in the blood)
• hypomagnesemia (low level of magnesium in the blood)
• signs and symptoms of bleeding in the stomach or intestine (black tarry bowel motions or blood in your bowel motions)

Diet and Lifestyle Advice

Natural Remedies vs DOMI DT DISPERSIBLE TABLET - what works faster?

Speed of action: Which is faster?

• DOMI DT DISPERSIBLE TABLET starts working within 30 to 60 minutes after ingestion. It blocks dopamine receptors in the brain, helping relieve nausea and vomiting quickly
• Natural remedies may take longer to show effects as they work by soothing the digestive system gradually. However, some remedies like ginger or peppermint may provide mild relief within 30 to 60 minutes

Foods to eat when taking DOMI DT DISPERSIBLE TABLET:

• Rice, oatmeal, toast, boiled potatoes
• Lean meats, eggs, tofu, lentils
• Ginger & herbal teas
• Bananas & apples
• Yogurt & probiotics

Foods to avoid when taking DOMI DT DISPERSIBLE TABLET:

• Spicy & oily foods
• Caffeinated drinks (coffee, tea, energy drinks)
• Carbonated beverages
• High-fat & processed foods
• Dairy (if lactose intolerant)

Lifestyle changes for better digestion:

• Chew food slowly to improve digestion and prevent bloating
• Avoid overeating - opt for small, frequent meals instead of large portions
• Take a short walk after meals (10-15 minutes) to aid digestion
• Drink warm water throughout the day to support digestion
• Sleep on your left side to reduce acid reflux
• Avoid lying down immediately after meals and wait for at least 2-3 hours

Natural ways to reduce nausea - Do they work?

Effective Natural Remedies for Nausea - For mild nausea, these remedies can be effective

• Ginger
• Peppermint
• Lemon & citrus scents
• Acupressure (P6 Pressure Point)
• Stay hydrated

Drug - Drug interaction

Medications to Avoid: Can I take DOMI DT DISPERSIBLE TABLET with other medications?

Drug - Food interaction

Potential Food Interactions:

Synopsis

More Information

DOMI DT DISPERSIBLE TABLET vs other anti-nausea medications – which one works best?

What to do if you experience side effects? (Quick tips):

Gastrointestinal Disorders:

Nausea & Vomiting: DOMI DT DISPERSIBLE TABLET is commonly prescribed for nausea, vomiting, and gastric motility disorders.

Common causes of Nausea & Vomiting:

• Indigestion & acid reflux (GERD)
• Gastric infections (food poisoning, stomach flu)
• Pregnancy (morning sickness)
• Motion sickness & vertigo
• Side effects of medications (antibiotics, painkillers, chemotherapy)

Treatment options:

• DOMI DT DISPERSIBLE TABLET: Works by blocking dopamine receptors in the gut, promoting faster stomach emptying, and managing nausea
• Ondansetron: Used for severe nausea (e.g., chemotherapy, post-surgery)
• Natural remedies: Ginger, peppermint tea, acupressure on the wrist (P6 point)

Gastric Motility Disorders: These conditions affect how food moves through the digestive tract, often causing bloating, nausea, and delayed gastric emptying.

Common conditions:

• Gastroparesis (Delayed stomach emptying)
• Functional Dyspepsia (Chronic indigestion)
• IBS (Irritable Bowel Syndrome) with slow digestion

Role of DOMI DT DISPERSIBLE TABLET in management

• Speeds up stomach emptying, reducing bloating & nausea
• Improves gut movement, managing food from sitting in the stomach too long
• Enhances digestion, making it useful for acid reflux & bloating

FAQs About DOMI DT DISPERSIBLE TABLET

Q: What is DOMI DT DISPERSIBLE TABLET used for?

A: DOMI DT DISPERSIBLE TABLET is used to manage in post-operative vomiting, drug-induced nausea and vomiting, vomiting due to radiation and anticancer drugs and in acute vomiting due to a variety of causes such as fever, gastritis, pancreatitis, uremia and hepatitis.

Q: How long does DOMI DT DISPERSIBLE TABLET stay in the system?

A: DOMI DT DISPERSIBLE TABLET have half-life approximately 7-9 hours in healthy adults. Typically takes around 35-45 hours (5 half-lives) for the drug to be fully cleared from the system.

Q: Can I take DOMI DT DISPERSIBLE TABLET for acid reflux?

A:DOMI DT DISPERSIBLE TABLET is mainly used for nausea, but it may provide some relief for acid reflux symptoms. If acid reflux is due to slow stomach emptying (gastroparesis), it can improve digestion by increasing stomach motility.

Q: When reflux is associated with nausea and bloating, does DOMI DT DISPERSIBLE TABLET can provide relief?

A: Yes, DOMI DT DISPERSIBLE TABLET can help when reflux is accompanied by nausea, bloating, and slow stomach emptying (gastroparesis).

Q: Is DOMI DT DISPERSIBLE TABLET safe for long-term use?

A:Prolonged use of DOMI DT DISPERSIBLE TABLET should be monitored by a doctor to manage potential side effects.

Q: Can Children take DOMI DT DISPERSIBLE TABLET?

A:Consult a pediatrician before giving DOMI DT DISPERSIBLE TABLET to children.

Q: How long can I take DOMI DT DISPERSIBLE TABLET?

A: It is recommended that DOMI DT DISPERSIBLE TABLET be taken for the shortest period and at the lowest dose. This is because DOMI DT DISPERSIBLE TABLET can cause an irregular heartbeat when taken for a longer period or at a high dose.

Q: Can I take DOMI DT DISPERSIBLE TABLET with antibiotics?

A: Use of DOMI DT DISPERSIBLE TABLET with antibiotics like erythromycin, levofloxacin, and some antifungals is not recommended as this can cause interaction.

Q: Does DOMI DT DISPERSIBLE TABLET increase milk secretion?

A: Yes, DOMI DT DISPERSIBLE TABLET may increase milk secretion also known as galactorrhoea. This is an uncommon side effect of using DOMI DT DISPERSIBLE TABLET. Talk to your doctor if you are experiencing this side effect while taking this medicine.

Q: Does DOMI DT DISPERSIBLE TABLET cause Heart problems?

A: DOMI DT DISPERSIBLE TABLET may be associated with an increased risk of heart problems (like an irregular heartbeat) and heart attacks. The risk also increases when it is given together with other medicines.

Q: Does DOMI DT DISPERSIBLE TABLET cause dry mouth?

A: Yes. it can cause dry mouth. A dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying.

Q: What is the best time to take DOMI DT DISPERSIBLE TABLET?

A: It is recommended to take DOMI DT DISPERSIBLE TABLET before meals. If taken after meals, absorption of the medicine is somewhat delayed. Patients should try to take each dose of it at a scheduled time to avoid missing a dose.

Q: Is DOMI DT DISPERSIBLE TABLET safe during pregnancy?

A: DOMI DT DISPERSIBLE TABLET is classified as Pregnancy Category C, there is limited human research, and it should only be used if the benefits outweigh potential risks. It crosses the placenta, but no significant birth defects have been reported in studies.

Q: Can I take DOMI DT DISPERSIBLE TABLET with antacids?

A: Yes. But take DOMI DT DISPERSIBLE TABLET before meals (at least 30 minutes before food) or take antacids after meals, if needed, but at least 1-2 hours apart from it.

References

1. KD Tripathi. Antiemetics. Essentials of Medical Pharmacology. Eighth edition. 2019. Page - 414.
2. Rhew K, Han N, Oh JM. Impact of Safety Warning on Domperidone Prescribing for Geriatric Patients in South Korea: Analysis of National Insurance Claim Data. NIH National Library of Medicine, National Centre for Biotechnology Information. Pubmed Central. August 2019. [Accessed on 14th June 2025]
3. NIH National Library of Medicine, National Centre for Biotechnology Information. Pubchem. Domperidone. [Accessed on 14th June 2025]
4. Savio C Reddymasu, Irfan Soykan, Richard W McCallum. Domperidone: review of pharmacology and clinical applications in gastroenterology. NIH National Library of Medicine, National Centre for Biotechnology Information. Pubmed.gov. September 2007. [Accessed on 14th June 2025] 
5. S.C. Zentiva S.A. Electronic Medicines Compendium (emc). [Revised in April 2021] [Accessed on 14th June 2025] 
6. Torrent Pharmaceuticals Ltd. Domstal DT (Domperidone). [Revised in February 2022]. [Accessed on 14th June 2025] 
7. Torrent Pharmaceuticals Ltd. Domstal (Domperidone). [Revised in April 2022]. [Accessed on 14th June 2025]
8. Torrent Pharmaceuticals Ltd. Domstal OD (Domperidone). [Accessed on 14th June 2025]
9. Janssen-Cilag (New Zealand) Ltd. Medsafe. [Revised in November 2020]. [Accessed on 14th June 2025]
10. Morepen Laboratories Ltd. DOM DT 20mg, DOM DT 5mg [Accessed on 14th June 2025]

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Last updated on 16 Jun 2025 | 08:59 AM(IST)