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Introduction About DOLOSPAN OD TABLET
DOLOSPAN OD TABLET contains Dexketoprofen which belongs to a group of medicines called Painkillers. It is used to manage mild to moderate pain such as muscular pain, painful period (dysmenorrhoea), toothache.
DOLOSPAN OD TABLET is not recommended in patients who have asthma, serious heart failure, moderate to severe kidney problems, severe liver problems, peptic ulcer/stomach or bowel bleeding, perforation, Crohn’s disease or ulcerative colitis (bowel disease with chronic inflammation). Consult your doctor before taking this medicine.
DOLOSPAN OD TABLET should be used with caution in patients suffering from high blood pressure, stroke, diabetes. Consult your doctor before taking this medicine.
DOLOSPAN OD TABLET is not recommended for use in pregnant and breastfeeding women, in children and adolescents below 18 years of age. It should be used with caution in elderly patients. Consult your doctor before taking this medicine.
The most common side effects of taking DOLOSPAN OD TABLET are nausea, vomiting, upper quadrants abdominal pain, diarrhoea, indigestion. Contact your physician if any of the symptoms worsen.
Uses Of DOLOSPAN OD TABLET
- To manage mild to moderate pain
How DOLOSPAN OD TABLET Works
DOLOSPAN OD TABLET works by blocking the effect of a natural chemicals called prostaglandins which are responsible for pain and inflammation. Thus, helps to manage pain and inflammation effectively.
How to use DOLOSPAN OD TABLET
Take DOLOSPAN OD TABLET as advised by your physician. It can be taken with food, as it helps to decrease the risk of stomach or bowel side effects. If you have acute pain, take this medicine on an empty stomach (at least 30 minutes before meals).
Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of DOLOSPAN OD TABLET
Common
- nausea, vomiting, upper quadrants abdominal pain, diarrhoea, indigestion
Uncommon
- spinning sensation (vertigo), dizziness
- sleepiness
- disturbed sleep
- nervousness
- headache
- palpitations
- flushing
- inflammation of the stomach lining (gastritis)
- constipation, dry mouth, flatulence
- skin rash
- tiredness
- pain
- feeling feverish and shivering
- feeling unwell (malaise)
Rare
- peptic ulcer, perforation or bleeding (which may be seen as vomiting blood or black stools)
- fainting
- high blood pressure
- too-slow breathing
- water retention, peripheral swelling (Ex. swollen ankles)
- laryngeal oedema (swelling of throat)
- loss of appetite (anorexia)
- abnormal sensation
- itchy rash
- acne
- increased sweating
- back pain
- passing urine frequently
- menstrual disorders
- prostate problems
- liver cell injury (hepatitis)
- acute renal failure
Stop taking DOLOSPAN OD TABLET and contact your physician immediately if you experience any of the following side effects:
- stomach/bowel problems (Ex. stomach pain, heartburn or bleeding)
- a skin rash or any lesion inside the mouth or on the genitals or any sign of an allergy
How To Manage Side Effects
Dry mouth:
Dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying. Consult your doctor if the dry mouth gets worse.
Headache:
Rest and relax. Drink plenty of fluids such as water or ORS (Oral Rehydrating Solution) and apply a pain-relieving balm on the head if necessary. Contact your doctor if your headache did not improve.
Nausea and vomiting:
Take DOLOSPAN OD TABLET, with or just after a meal. Stick to simple meals. Avoid eating oily or spicy food. Contact your doctor if your nausea and vomiting did not improve.
Constipation:
Take fiber rich foods in your diet such as fresh fruits, vegetables and whole grain cereals and drink plenty of fluids. Exercise more regularly and stay active. Contact your doctor if constipation persist.
Stomach pain:
Try to have smaller meals but take frequently. Keep a heat pad on your stomach. Do not self-manage and contact your doctor if the stomach pain did not improve.
Skin rash:
Avoid hot bath because hot water can irritate your skin further. Do not scratch the affected area. Use sunscreen and wear protective clothing while going outside. Use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if your rashes worsen.
Flatulence:
Eat smaller and frequent meals. Eat and drink slowly and exercise regularly. If the flatulence does not improve, contact your doctor.
Diarrhoea:
Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Do not take any medicine on your own for managing diarrhoea. Contact your doctor if your diarrhoea did not improve.
Loss of appetite:
Eat when you are hungry. Eat smaller meals more often than usual. Snack only when you're hungry. Eat a nutritious snack which is rich in calories and protein, such as dried fruit and nuts. Contact your doctor if your appetite did not improve.
Warning & Precautions
Pregnancy
DOLOSPAN OD TABLET is not recommended for use in pregnant women (especially during third trimester) or planning to become pregnant. Consult your doctor before taking DOLOSPAN OD TABLET.
Breastfeeding
DOLOSPAN OD TABLET is not recommended for use in breast feeding women. Consult your doctor before taking DOLOSPAN OD TABLET.
Driving and Using Machines
Do not drive or operate any machines if you feel dizziness or drowsiness after taking DOLOSPAN OD TABLET.
Kidney
DOLOSPAN OD TABLET is not recommended for use in patients with moderate to severe kidney problems. It should be used with caution in patients suffering from kidney problems. Consult your doctor before taking DOLOSPAN OD TABLET.
Liver
DOLOSPAN OD TABLET is not recommended for use in patients with severe liver problems. It should be used with caution in patients suffering from liver problems. Consult your doctor before taking DOLOSPAN OD TABLET.
Allergy
Do not take this medicine if you are allergic to Dexketoprofen, Acetylsalicylic acid or to other non-steroidal anti-inflammatory medicines or any of the other ingredients of this medicine.
Lungs
DOLOSPAN OD TABLET is not recommended in patients who have asthma or have suffered attacks of asthma, acute allergic rhinitis (a short period of inflamed lining of the nose), nasal polyps (lumps within the nose due to allergy), urticaria (skin rash), angioedema (swollen face, eyes, lips or tongue or respiratory distress) or wheezing in the chest after taking acetylsalicylic acid or other non-steroidal anti-inflammatory medicines. Consult your doctor before taking DOLOSPAN OD TABLET.
Heart Disease
DOLOSPAN OD TABLET is not recommended in patients with serious heart failure. It should be used with caution in patients suffering from high blood pressure and/or heart failure. Consult your doctor before taking DOLOSPAN OD TABLET.
Others
DOLOSPAN OD TABLET is not recommended for use if you:
- suffered from photoallergic or phototoxic reactions (a particular form of reddening and/or blistering of the skin exposed to sunlight)
- have or had peptic ulcer/stomach or bowel bleeding, perforation (including due to previous use of painkillers)
- have chronic digestive problems (Ex. indigestion, heartburn)
- have bowel disease with chronic inflammation (Crohn’s disease or ulcerative colitis)
- have bleeding disorder or a blood clotting disorder
- are severely dehydrated (have lost a lot of body fluids) due to vomiting, diarrhoea or insufficient intake of fluids
- have chicken pox
Before taking DOLOSPAN OD TABLET, inform your doctor if you:
- suffer from allergy or if you have had allergy problems in the past
- suffer from very poor hydration and reduced blood volume due to an excessive loss of fluids (Ex. from excessive urination, diarrhoea or vomiting)
- have stroke
- have diabetes
- have high cholesterol levels
- smoke
- suffer from a disorder in the formation of blood and blood cells
- have systemic lupus erythematosus or mixed connective tissue disease (immune system disorders that affect connective tissue)
Use in Pediatrics:
DOLOSPAN OD TABLET is not recommended for use in children and adolescents below 18 years of age as safety and efficacy have not been established. Consult your doctor before taking DOLOSPAN OD TABLET.
Use in Geriatrics:
DOLOSPAN OD TABLET should be used with caution in elderly patients. Consult your doctor before taking DOLOSPAN OD TABLET.
Interactions
A. Drug - Drug interactions:
Before taking DOLOSPAN OD TABLET inform your doctor if you are taking any of the following medicine:
- selective serotonin reuptake inhibitors (used to manage depression) Ex. citalopram, escitalopram
- medicines used to manage or manage blood clots Ex. aspirin, warfarin, heparin, streptokinase, alteplase
- corticosteroids (used to manage inflammatory conditions) Ex. dexamethasone, betamethasone
- lithium (used to manage certain mood disorders)
- methotrexate (used to manage cancer or to supress immune system)
- hydantoins and phenytoin (used for epilepsy)
- sulfamethoxazole, amikacin, ciprofloxacin, levofloxacin (used for bacterial infections)
- captopril, enalapril, candesartan, hydrochlorothiazide, metoprolol, digoxin (used for high blood pressure and heart problems)
- pentoxifylline and oxpentifylline (used to manage chronic venous ulcers)
- zidovudine, tenofovir (used to manage HIV infections)
- sulfonylureas (used to manage diabetes) Ex. chlorpropamide and glibenclamide
- cyclosporin or tacrolimus (used to manage immune system diseases and in organ transplant)
- probenecid (used to manage gout)
- mifepristone (used to terminate a pregnancy)
- deferasirox (used to manage iron overload)
- pemetrexed (used to manage cancer)
- ketoprofen (used to manage pain)
- fenofibrate (used to lower cholesterol levels)
Overdosage:
If you or anyone else accidentally take too much of DOLOSPAN OD TABLET, contact your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Dexketoprofen |
| Pharmacological Category | : | Non-steroidal anti-inflammatory drugs (NSAIDs) |
| Therapeutic Indication | : | Mild to moderate pain |
| Dosage Forms | : | Tablet, Injection, Gel, Spray |
More Information
- Keep DOLOSPAN OD TABLET out of reach of children
- Store DOLOSPAN OD TABLET below 30°C
FAQs About DOLOSPAN OD TABLET
Q: Does DOLOSPAN OD TABLET cause asthma?
A: DOLOSPAN OD TABLET can cause asthma attacks or bronchospasm, particularly in patients allergic to acetylsalicylic acid or NSAIDs. Inform your doctor if you suffer from asthma combined with chronic rhinitis, chronic sinusitis and/or nasal polyposis as you have a higher risk of allergy to acetylsalicylic acid and/or NSAIDs than the rest of the population.
Q: Can DOLOSPAN OD TABLET be taken with food?
A: Take DOLOSPAN OD TABLET according to the doctors advise. Take the medicine with an adequate amount of water. It should be taken with food, as it helps to decrease the risk of stomach or bowel side effects. However, if you have acute pain, take the medicine on an empty stomach, i.e. at least 30 minutes before meals, as this helps DOLOSPAN OD TABLET start working a little faster.
Q: Does DOLOSPAN OD TABLET hide symptoms of infections?
A: Yes. DOLOSPAN OD TABLET may hide signs of infections such as fever and pain. It is therefore possible that DOLOSPAN OD TABLET may delay appropriate management of infection, which may lead to an increased risk of complications. This has been observed in pneumonia caused by bacteria and bacterial skin infections related to chickenpox. If you take DOLOSPAN OD TABLET while you have an infection and your symptoms of the infection persist or worsen, consult a doctor without delay.
Q: Does DOLOSPAN OD TABLET cause heart attack?
A: DOLOSPAN OD TABLET may be associated with a small increased risk of heart attack or stroke. Inform your doctor before taking this medicine if you have heart problems, previous stroke or think that you might be at risk of these conditions (for example if you have high blood pressure, diabetes or high cholesterol or are a smoker). The risk is more likely with high doses and prolonged management. Do not exceed the recommended dose or duration of management.
Q: Can I take DOLOSPAN OD TABLET during pregnancy?
A: No, DOLOSPAN OD TABLET is not recommended for use in pregnant women (especially during third trimester) or planning to become pregnant. Consult your doctor before taking DOLOSPAN OD TABLET.
References
1. Sean C Sweetman. Analgesics Anti-inflammatory Drugs and Antipyretics. Martindale The Complete Drug Reference. 36th edition. 2009. Page- 73.
2. Moore RA, Barden J. Systematic review of dexketoprofen in acute and chronic pain. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central. October 2008. [Accessed on 8th January 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585070/
3. Bethesda (MD). Oxaceprol. NIH National Library of Medicine, National Center for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 8th January 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585070/
4. LABORATORIOS MENARINI, S.A. Electronic Medicines Compendium (EMC). [Revised in March 2021] [Accessed on 8th January 2022]. https://www.medicines.org.uk/emc/files/pil.159.pdf
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