Dolo 650 Tablet 15's

Introduction About DOLO 650MG TABLET

DOLO 650MG TABLET is a fever and pain reducing medicine. It contains a medicine called paracetamol which alleviate pain and reduce fever by inhibiting the release of certain chemicals within the body that causes pain and fever. It is commonly used to provide relief from headaches, migraines, tooth pain, sore throats, periods pain, joint pain, muscle aches, and symptoms of the common cold.

It is recommended to take DOLO 650MG TABLET as directed by your doctor. Taking it preferably with meals may reduce stomach upset. Do not take more than the recommended dosages as it could affect your liver. DOLO 650MG TABLET starts working within 30 minutes of its intake. Leave a time gap of 4 hours between each dose of DOLO 650MG TABLET.

In most cases, DOLO 650MG TABLET is well-tolerated, with side effects being rare. However, some individuals may experience temporary stomach discomfort, nausea, or vomiting. If any of these side effects persist or become troublesome, consult your doctor. Do not take this medicine, without consulting your doctor if you have severe liver problems. Consult your doctor before taking DOLO 650MG TABLET, if you are pregnant or breastfeeding.

Before using this medication, inform your doctor if you have any liver or kidney issues, are allergic to paracetamol, or are taking other medications as a precaution.

Uses Of DOLO 650MG TABLET

• Fever
• Headache & body pain
• Menstrual pains
• Signs of Flu, sore throat

Key Benefits of DOLO 650MG TABLET:

• Fast pain relief: Works within 30-60 minutes for headaches, muscle aches, and toothaches.
• Effective fever reducer: Helps lower body temperature during fever caused by infections.
• Gentle on the stomach: Safer for sensitive stomachs compared to NSAIDs.
• Minimal side effects: Most users experience no adverse reactions when taken as directed.
• Affordable and accessible: Cost-effective and available over-the-counter.
• Trusted brand: Backed by years of positive feedback and recommended by healthcare professionals.
• Convenient options: Available in tablets and syrups for different preferences.

How DOLO 650MG TABLET Works

DOLO 650MG TABLET works effectively for fever, headaches, and body pains by containing paracetamol, which reduces fever and alleviates pain. It helps lower body temperature by acting on the brain's temperature control center, making it an ideal choice for fever management. For headaches and body pains, paracetamol blocks the production of pain-causing chemicals in the body, providing quick relief from conditions like headaches, muscle pain, and joint discomfort. DOLO 650MG TABLET is known for its fast-acting and gentle effects, making it a trusted solution for mild to moderate pain and fever.

How to use DOLO 650MG TABLET

DOLO 650MG TABLET is typically taken orally with or without food. For tablets:

• Swallow the tablet whole with a glass of water.
• Do not crush or chew the tablet.

What is the recommended dosage for adults?

• For Adults: The usual dose is 1 tablet (650 mg) every 4-6 hours as needed for pain or fever. Do not exceed 4 tablets (2600 mg) in 24 hours.

What If I Forget to Take DOLO 650MG TABLET?

• If you forget to take a dose, take it as soon as you remember unless it's almost time for your next scheduled dose. Never double dose to make up for a missed dose.

Can children take DOLO 650MG TABLET, and if so, what is the proper dosage?

• Dosage for children should be prescribed by a healthcare provider, as the dosage varies based on age and weight.

How many DOLO 650MG TABLET can be taken in a day?

• The recommended maximum dosage for adults is 4 tablets (2600 mg) in a 24-hour period. This means you can take 1 tablet (650 mg) every 4-6 hours as needed but ensure that you do not exceed 4 tablets in 24 hours.
• Children's dosage should be prescribed by a healthcare provider based on age and weight.

Is it safe to take DOLO 650MG TABLET with food or on an empty stomach?

• DOLO 650MG TABLET can be taken with or without food. It is generally well-tolerated whether you take it on an empty stomach or after eating. However, if you have a sensitive stomach or experience discomfort, it may be helpful to take it with food to minimize any potential stomach irritation.

Overdosage:

• Overdose Warning: Taking too much paracetamol can cause severe liver damage, which can be life-threatening. If you suspect an overdose, seek immediate medical attention, even if you feel fine. Symptoms of overdose include nausea, vomiting, loss of appetite, confusion, and yellowing of the skin or eyes.

Side Effects Of DOLO 650MG TABLET

DOLO 650MG TABLET is safe and well-tolerated. In some individuals it may cause mild nausea.

When To Consult your doctor?

Stop taking DOLO 650MG TABLET and consult your doctor in case of:

• Signs of liver damage (such as nausea, vomiting, yellowing of whites of eyes and skin, skin itchiness, yellowing of urine, severe stomach pain)
• When fever does not subside

Warning & Precautions

Pregnancy

Use with Caution

Paracetamol is classified as Category C by the U.S. FDA, which means that animal reproduction studies have shown some adverse effects on the fetus, but there are no adequate or well-controlled studies in humans. Therefore, DOLO 650MG TABLET should be used in pregnant women only if considered necessary by the physician. Caution is advised when taking DOLO 650MG TABLET during pregnancy, especially during the first trimester.

Breastfeeding

Safe

Paracetamol (DOLO 650MG TABLET) is considered safe for use during breastfeeding in recommended doses. It passes into breast milk in very small amounts, and no harmful effects on the infant are typically seen. However, it’s always best to consult a doctor before taking any medication while breastfeeding.

Driving and Using Machines

Use with Caution

DOLO 650MG TABLET has no influence on the ability to drive and operate machinery.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking this medicine as it could increase the risk of liver damage

Kidney

Use with Caution

People with pre-existing kidney issues should use DOLO 650MG TABLET with caution. If you have kidney disease or reduced kidney function, you may need a lower dose or special monitoring. Always consult your healthcare provider before using DOLO 650MG TABLET if you have kidney problems.

Liver

Use with Caution

Caution is especially important for those with liver disease or liver impairment, as paracetamol is metabolized in the liver. Overuse or high doses can lead to severe liver damage. If you have liver problems, avoid taking DOLO 650MG TABLET or use it only under strict medical supervision. The maximum dose should not exceed the prescribed limit.

Allergy

Contraindicated

Do not take DOLO 650MG TABLET if you are allergic to Paracetamol.

Use In Pediatrics

Consult your doctor

DOLO 650MG TABLET is typically formulated for adults (650 mg per tablet) and children aged 12 years or older. It is not suitable for young children due to the high dosage. Children under 12 years of age should not use this formulation unless specifically prescribed by a healthcare provider.

• For pediatric use, lower doses of paracetamol (in syrup or suspension form) are typically recommended.
• The recommended dose of paracetamol for children generally depends on the child's weight and age. A typical pediatric dose is about 10-15 mg/kg body weight every 4-6 hours, without exceeding the maximum daily dose, which is usually 60 mg/kg per day.

Use In Geriatrics

Use with Caution

DOLO 650MG TABLET should be used with caution in elderly patients with liver problems. Therefore, consult your doctor before taking it.

Drug - Drug interaction

Top Drug interactions for DOLO 650MG TABLET:

1. Alcohol:

• Interaction: Alcohol consumption while taking paracetamol can increase the risk of liver damage.
• Effect: Both alcohol and paracetamol are metabolized in the liver, and combining them may overwhelm the liver’s ability to process these substances safely. This can lead to hepatotoxicity (liver toxicity), especially in individuals who consume alcohol regularly.

2. Warfarin (and other anticoagulants):

• Interaction: Paracetamol may increase the anticoagulant effect of warfarin and other blood-thinning medications.
• Effect: Regular use of paracetamol can increase the risk of bleeding in people taking anticoagulants like warfarin. It may reduce the effectiveness of blood clotting, leading to prolonged bleeding times.

3. Antiepileptic Drugs (e.g., Phenytoin, Carbamazepine):

• Interaction: Antiepileptic drugs such as phenytoin and carbamazepine can enhance the breakdown of paracetamol in the liver, reducing its effectiveness.
• Effect: Paracetamol may be cleared from the body more quickly, potentially leading to reduced pain relief or fever control. It may also increase the risk of liver damage.

4. Isoniazid (used for tuberculosis treatment):

• Interaction: Isoniazid can increase the toxicity of paracetamol.
• Effect: When taken together, isoniazid may increase the risk of liver damage caused by paracetamol, especially with long-term use or high doses.

5. Rifampicin (another anti-tuberculosis drug):

• Interaction: Rifampicin can enhance the metabolism of paracetamol in the liver.
• Effect: This interaction can reduce the effectiveness of paracetamol and may increase the risk of liver damage in individuals taking both medications.

6. Chloramphenicol:

• Interaction: Chloramphenicol, an antibiotic, may interact with paracetamol by affecting its metabolism.
• Effect: The combination may increase the risk of blood disorders or affect the way paracetamol works in the body, especially in people with existing blood-related issues.

7. Metoclopramide:

• Interaction: Metoclopramide, a medication used to treat nausea and gastrointestinal issues, may increase the absorption of paracetamol.
• Effect: The combination may lead to faster or increased absorption of paracetamol, potentially enhancing its effects. This can increase the risk of overdosing and liver damage if not monitored.

8. Antacids (e.g., Magnesium Hydroxide):

• Interaction: Antacids can sometimes affect the absorption of paracetamol.
• Effect: In some cases, antacids may decrease the effectiveness of paracetamol by reducing its absorption. This can potentially lead to reduced pain relief.

More Information

Why Choose DOLO 650MG TABLET?

DOLO 650MG TABLET is trusted by millions as a reliable solution for fever and pain relief.

Here are some key reasons why people choose DOLO 650MG TABLET:

1. Effective Pain and Fever Relief

• DOLO 650MG TABLET is highly effective in managing mild to moderate pain, including headaches, toothaches, muscle pain, and menstrual cramps.
• It is also a trusted fever reducer, offering relief from fever associated with colds, flu, and other common illnesses.

2. Quick Action

• Users report rapid relief from pain and fever, typically within 30 to 60 minutes of consumption.

3. Safe for Most Users

• When taken as directed, DOLO 650MG TABLET is considered safe for most individuals, including those with sensitive stomachs, as it has fewer gastrointestinal side effects compared to other painkillers like NSAIDs (e.g., ibuprofen).

4. Widely Available

• DOLO 650MG TABLET is available in various forms (tablets, suspension), making it easy to find and use.

5. Minimal Side Effects

• Most users tolerate DOLO 650MG TABLET well, with side effects being rare. However, it is crucial to follow the recommended dose to avoid the risk of liver damage.

6. Trusted Brand

• DOLO 650MG TABLET is a reliable and well-known brand in the market, trusted by healthcare professionals and patients for years.

7. Affordability

• DOLO 650MG TABLET is affordable and offers a cost-effective option for pain and fever relief compared to some other medications.

FAQs About DOLO 650MG TABLET

Q: What is DOLO 650MG TABLET used for?

A: DOLO 650MG TABLET is used to provide relief from fever and body pains. It contains a medicine called paracetamol which has fever and pain reducing properties. It works by blocking the release of certain chemicals in the body that triggers fever or causes pain which makes it a suitable medicine to manage fever and various pain conditions like headache, body pain, muscle pain, menstrual cramps, tooth pain, etc.

Q: Does DOLO 650MG TABLET make you sleepy?

A: DOLO 650MG TABLET (paracetamol) does not generally cause drowsiness or sleepiness. Its primary function is to act as an analgesic (pain reliever) and an antipyretic (fever reducer). While some pain medications can cause drowsiness, paracetamol usually does not affect alertness or energy levels. If you experience unexpected drowsiness, it’s best to consult your doctor to rule out other potential causes.

Q: Can we use DOLO 650MG TABLET for stomach pain?

A: DOLO 650MG TABLET is not typically recommended for stomach pain unless prescribed by a doctor. Paracetamol (the active ingredient) is primarily used to relieve pain from headaches, body aches, or fevers, rather than gastrointestinal pain. For stomach pain, antispasmodics or medications specifically designed to target digestive discomfort are often more effective. Always consult a healthcare provider before using pain relievers for stomach issues.

Q: What is the side effect of DOLO 650MG TABLET?

A:DOLO 650MG TABLET is generally safe when taken as directed. It may cause damage to the liver when taken in higher doses within a short period. Therefore, taking each dosage within 4 to 6 hours intervals is recommended, especially if you have any liver problems.

Q: Is DOLO 650MG TABLET a sleeping pill?

A: No, DOLO 650MG TABLET is not a sleeping pill. It is a pain reliever and fever reducer containing paracetamol. It is formulated to relieve mild to moderate pain and fever but does not have sedative properties. For those seeking a sleep aid, a different type of medication would be recommended under a healthcare provider's guidance.

Q: Can I take 2 DOLO 650MG TABLET in a day?

A: Yes, you can take DOLO 650MG TABLET up to 2 times a day, with the standard dosage being 1 tablet every 4 to 6 hours. However, it’s crucial not to exceed 4,000 mg (around 6 tablets) within 24 hours to avoid the risk of liver damage. It’s also recommended to space the doses evenly to prevent overloading your system. Always follow your doctor’s advice if unsure about the dosage.

Q: Can I take DOLO 650MG TABLET without a fever?

A: Yes, DOLO 650MG TABLET can be used for pain relief even in the absence of a fever. Paracetamol, the active ingredient, works effectively for pain management, whether or not a fever is present. Many people use it to relieve various types of pain, including headaches and muscle soreness, even if they do not have a fever.

Q: Which is better, DOLO 650MG TABLET or Combiflam?

A: DOLO 650MG TABLET and Combiflam serve slightly different purposes. DOLO 650MG TABLETcontains paracetamol, which primarily relieves pain and reduces fever. Combiflam combines paracetamol with ibuprofen, making it more effective for pain involving inflammation (such as joint pain or muscle sprains). If the pain involves inflammation, Combiflam might be more suitable, but DOLO 650MG TABLET is effective for general pain and fever. Always consult a doctor to find the best option for your specific symptoms.

Q: Is DOLO 650MG TABLET good for tooth pain?

A: Yes, DOLO 650MG TABLET can help relieve tooth pain due to its pain-relieving effects. However, it will not address the underlying cause, such as an infection or cavity. DOLO 650MG TABLET can provide temporary relief, but a dentist's visit is recommended to treat the root cause of the tooth pain.

Q: Is DOLO 650MG TABLETgood for a cold?

A: DOLO 650MG TABLET can help alleviate symptoms like fever and body aches associated with a cold. While it does not treat the cold virus itself, it can make you feel more comfortable by reducing fever and relieving aches. For complete relief, other medications or home remedies specifically targeting cold symptoms, such as decongestants, might be needed.

References

1. KD. Tripathi. NSAIDs and Antipyretic-Analgesics. Essentials of Medical Pharmacology. Seventh edition. 2013. Page-206.
2. Ulderico Freo, Chiara Ruocco, Alessandra Valerio, Irene Scagnol and Enzo Nisoli. Paracetamol: A Review of Guideline Recommendations. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. August 2021. [Accessed on 11th June 2025] 
3. Zentiva Pharma UK Limited. Electronic Medicines Compendium (EMC). [Revised in May 2022] [Accessed on 11th June 2025]  
4. GlaxoSmithKline Asia Private Limited. Crocin 500 mg and Crocin 650 mg (Paracetamol). [Accessed on 11th June 2025] 

Useful Diagnostic Tests

• Fever Basic
• Healthians Fever Package
• Fever Package
• Fever Profile-Advanced
• Fever Panel-Basic

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed For Accuracy By Dr. Sankara Babu Gorle - MBBS, MD (Pharmacology)

Last updated on 12 Jun 2025 | 03:51 PM(IST)