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Introduction About DIVON SPRAY
DIVON SPRAY contains Diclofenac, which belongs to the group of medicines called Nonsteroidal Anti-Inflammatory Drugs (NSAIDs). It is used to manage pain and inflammation related to muscle and joint injuries (Ex. sprains, strains, bruises, sports injuries, backache), tendonitis (Ex. tennis elbow), osteoarthritis (flexible tissue at the ends of bones wears down), swelling around the elbow or knee, or post-trauma.
If you are using DIVON SPRAY for arthritis, your doctor may want to review your management regularly. If the pain and swelling do not improve within 7 days or if they worsen, inform your doctor. Avoid smoking or going near naked flames, as there might be a risk of severe burns.
DIVON SPRAY is not recommended for use in patients having kidney failure, severe joint pain of recent onset (unrelated to an injury or period of overuse), illness, fever, or any other symptoms along with the pain. Before using DIVON SPRAY, inform your doctor if you have any stomach or bowel ulcer, asthma, liver, kidney, or bleeding problems.
DIVON SPRAY is not recommended for use in pregnancy (especially in the last 3 months) and should be used in breastfeeding women only under medical advice. DIVON SPRAY is not recommended for use in children and adolescents (below 14 years of age).
Be cautious when sunbathing or using sun lamps, as your skin may be more sensitive to sunlight. The most common side effects of using DIVON SPRAY are skin rash, itching, reddening of the skin, etc. Call your doctor if any of the symptoms worsen.
Uses Of DIVON SPRAY
Manages pain and inflammation related to:
- Muscle and joint injuries (Ex. sprains, strains, bruises, sports injuries, backaches)
- Tendonitis (Ex. tennis elbow)
- Osteoarthritis
- Swelling around elbow or knee
- Post-trauma
How DIVON SPRAY Works
DIVON SPRAY relieves pain and inflammation by inhibiting certain enzymes (COX-1 and COX-2) involved in the synthesis of prostaglandins (chemicals responsible for inducing pain and inflammation).
How to use DIVON SPRAY
Apply DIVON SPRAY as advised by your physician. It is for external use only. Apply on healthy skin only. Wash your hands before and after application. Do not cover the applied area with occlusive bandages or plasters. Do not apply DIVON SPRAY on injured or infected skin.
In case of accidental contact with eyes, mucous membranes, or injured skin, wash the affected area with running water. If the irritation persists, call your doctor. Your doctor will decide a proper dose and duration for you depending upon your age, body weight, and severity of your condition.
Side Effects Of DIVON SPRAY
Common
- Skin rash, itching, reddening, burning sensation, or scaling of the skin
- Skin disorder (eczema)
- Skin inflammation in the applied area (rash, swelling, or papules)
Rare
- Bullous dermatitis (extensive skin changes with the appearance of redness, scaling, and large bubbles)
- Increased sun sensitivity (itching, swelling, blistering)
Stop using DIVON SPRAY and contact your doctor immediately if you experience any of the following side effects:
- Allergic reaction (skin rash with blisters, hives, wheezing, breathlessness, chest tightness, swollen face, lips, tongue, or throat)
- Serious skin reactions (Ex. exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis)
How To Manage Side Effects
Skin rash Or Itching
Avoid hot showers, as they can further irritate your skin. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. If the skin rash persists, contact your doctor.
Warning & Precautions
Pregnancy
Monitoring requiredDIVON SPRAY is not recommended for use in pregnancy (during the last 3 months). DIVON SPRAY should be used only under medical advice during the first 6 months of pregnancy. Consult your doctor for advice.
Breastfeeding
Monitoring requiredDIVON SPRAY should only be used under medical advice during breast-feeding as it passes into breast milk in small amounts. However, prolonged application on the breasts of nursing mothers or elsewhere on large areas of skin should be avoided. Consult your doctor for advice.
Driving and Using Machines
SafeDIVON SPRAY generally does not affect your ability to drive or use machines.
Kidney
Consult your doctorDIVON SPRAY is not recommended for use in patients with kidney failure. DIVON SPRAY should be used with caution in patients having other kidney problems. Consult your doctor for advice.
Liver
Use with CautionDIVON SPRAY should be used with caution in patients having liver problems. Consult your doctor for advice.
Allergy
ContraindicatedDIVON SPRAY is not recommended for use if you are allergic to diclofenac, aspirin, ibuprofen, other NSAIDs, peanuts, soya or any of the other ingredients of this medicine.
Lungs
Use with CautionDIVON SPRAY should be used with caution in patients having asthma. Consult your doctor for advice.
Use In Pediatrics
ContraindicatedDIVON SPRAY is not recommended for use in children (under 14 years of age). Consult your child’s doctor for advice.
Use In Geriatrics
Use with CautionDIVON SPRAY should be used with caution in elderly patients. Consult your doctor for advice.
Others
DIVON SPRAY is not recommended for use if you:
- Have severe joint pain of recent onset (unrelated to an injury or period of overuse)
- Feel ill, have a fever, or any other symptoms along with the pain
Before using DIVON SPRAY, inform your doctor if you:
- Have or had stomach or bowel ulcers
- Have a tendency for bleeding
- Have inflammatory bowel disease
- Are dehydrated
Interactions
A. Drug-Drug Interactions:
Before using DIVON SPRAY, inform your doctor if you are taking any of the following medicines:
- Medicines used to remove excess water from the body (Ex. spironolactone, furosemide)
- Medicines used to manage high blood pressure and other heart problems (Ex. captopril, atenolol, metoprolol, digoxin)
- Other medicines used for pain relief (Ex. aspirin, ibuprofen)
Overdosage:
If you or anyone else accidentally use too much of DIVON SPRAY, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Diclofenac |
| Pharmacological Category | : | Cyclooxygenase Inhibitors |
| Therapeutic Indication | : | Pain and inflammation |
| Dosage Forms | : | Tablet, Capsule, Dispersible tablet, Injection, Eye drops, Gel, Spray, Solution, Liniment, Suppository, Ointment, Transdermal patch, Spray |
More Information
Storage
- Keep DIVON SPRAY out of reach of children
- Store DIVON SPRAY below 30°C
FAQs About DIVON SPRAY
Q: Can I use DIVON SPRAY if I am taking paracetamol?
A: It is safe to use DIVON SPRAY with paracetamol, but this does not necessarily mean no interactions exist. Consult your doctor before taking any other medicine with DIVON SPRAY, especially other similar painkillers (NSAIDs).
Q: What if I forget to apply a dose of DIVON SPRAY?
A: If you forget to apply a dose of DIVON SPRAY, do it as soon as you remember. However, omit that dose if it's almost time for the next one. Do not apply a double quantity of DIVON SPRAY to make up for the missed dose.
Q: Can I stop using DIVON SPRAY on my own?
A: DIVON SPRAY management can be stopped at any time without requiring special care. However, you may feel pain or swelling in the affected area again. If you have any further queries on the use of this medicine, ask your doctor.
Q: Is DIVON SPRAY safe to use in asthmatic patients?
A: DIVON SPRAY should be used with caution if you have or ever had asthma. Consult your doctor for advice. Your doctor will determine a proper dose of DIVON SPRAY or select a suitable alternative management for you according to your condition.
Q: Can DIVON SPRAY be used during pregnancy?
A: DIVON SPRAY must not be used during the last 3 months of pregnancy, as it could harm your unborn baby or cause problems at delivery. It should only be used under medical advice during the first 6 months of pregnancy, and the dose and duration should be kept as small as possible. If you are pregnant, think you may be pregnant, or are planning for a baby, consult your doctor before using it.
Q: What if I accidentally swallow DIVON SPRAY?
A: If you or anyone else accidentally swallow DIVON SPRAY, see your doctor immediately or go to your nearest hospital. Take your medicine with you for the doctor to know what you’ve ingested.
Q: What is DIVON SPRAY used for?
A: DIVON SPRAY is used to manage pain and inflammation related to muscle and joint injuries (Ex. sprains, strains, bruises, sports injuries, backache), tendonitis (Ex. tennis elbow), osteoarthritis (flexible tissue at the ends of bones wears down), swelling around the elbow or knee, or post-trauma.
Q: What are the side effects of taking DIVON SPRAY?
A: The most common side effects of using DIVON SPRAY are skin rash, itching, reddening of the skin, etc. Call your doctor if any of the symptoms worsen.
Q: How does DIVON SPRAY work?
A: DIVON SPRAY relieves pain and inflammation by inhibiting certain enzymes (COX-1 and COX-2) involved in the synthesis of prostaglandins (chemicals responsible for inducing pain and inflammation).
Q: Who should not use DIVON SPRAY?
A: DIVON SPRAY is not recommended for use in patients with kidney failure, allergic to Diclofenac, aspirin, ibuprofen, other NSAIDs, peanuts, or soya, have severe joint pain of recent onset (unrelated to an injury or period of overuse), or feel ill, have fever, or have any other symptoms along with the pain.
Q: What precautions must be taken while using DIVON SPRAY?
A: DIVON SPRAY should be used with caution in patients having other kidney problems, liver problems, asthma, stomach or bowel ulcers, tendency for bleeding, inflammatory bowel disease, and dehydration. Consult your doctor for advice.
References
1. KD. Tripathi. Nonsteroidal Anti-inflammatory Drugs and Antipyretic-Analgesics. Essentials of Medical Pharmacology. Eighth Edition. 2019. Page – 221.
2. Sharma Y, Philip VM, Sharma S. Prospective, open-label, randomized, parallel group, comparative clinical study of two topical formulations of diclofenac diethylamine in the treatment of acute painful musculoskeletal conditions. Journal of Marine Medical Society. March 2020. [Accessed on 29th July 2024] https://www.marinemedicalsociety.in/article.asp?issn=0975-3605;year=2020;volume=22;issue=1;spage=35;epage=39;aulast=Sharma
3. Bariguian Revel, F., Fayet, M., & Hagen, M. Topical Diclofenac, an Efficacious Treatment for Osteoarthritis: A Narrative Review. NIH National Library of Medicine, National Center for Biotechnology Information. Pubmed Central. June 2020. [Accessed on 29th July 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211216/
4. GlaxoSmithKline Consumer Healthcare GmbH & Co. KG. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on 29th July 2024] https://www.medicines.org.uk/emc/files/pil.8775.pdf
5. GlaxoSmithKline Consumer Healthcare (UK). Electronic Medicines Compendium (EMC). [Revised in March 2020] [Accessed on 29th July 2024] https://www.medicines.org.uk/emc/files/pil.366.pdf
6. Pharbil Waltrop GmbH. Electronic Medicines Compendium (EMC). [Revised in June 2023] [Accessed on 29th July 2024] https://www.hpra.ie/img/uploaded/swedocuments/fa50ac92-f1d7-448f-9e35-01dc563f0dff.pdf
Useful Diagnostic Tests
- Complete Blood Count (CBC)/ Hemogram
- Liver Function Test (LFT)
- Rheumatoid Factor (RF)/RA Test Rheumatoid Arthritis Factor, Qualitative
- Basic Arthritis Care
- Extended Arthritis Care
- Advance Bone Care
- Comprehensive Bone Care
- Frequent Pain Check Package
- Autoimmune Arthritis Panel
- Arthritis Profile – Advanced


