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Introduction About DIRAB 10MG TABLET
DIRAB 10MG TABLET contains Dexrabeprazole which belongs to the group of medicines called Proton Pump Inhibitor (PPI). It is used to manage acid peptic disease (group of diseases involving excess acid production in the stomach), Gastro esophageal reflux disease (reflux of stomach contents backwards from stomach into food pipe), gastric and duodenal ulcers (ulcers or sores on the lining of stomach and intestine).
DIRAB 10MG TABLET is also used to manage erosive esophagitis (inflammation or erosion of esophagus) and Zollinger-Ellison syndrome (a rare condition that cause cancer (gastrinomas) in the pancreas or intestine). Before taking DIRAB 10MG TABLET, inform your doctor if you have gastric cancer.
There is no information available on the use of DIRAB 10MG TABLET in pregnant women and it can be used safely in breastfeeding women. Contact your doctor before taking it.
Uses Of DIRAB 10MG TABLET
Manage:
- Acid peptic disease
- Gastro esophageal reflux disease
- Gastric and duodenal ulcers
- Erosive esophagitis
- Zollinger-Ellison syndrome
How DIRAB 10MG TABLET Works
DIRAB 10MG TABLET is a Proton Pump Inhibitor (PPI) works by decreasing gastric acid secretion by inhibiting an enzyme (protein) called H+/K+-ATPase on the gastric parietal cells (responsible for gastric acid secretion).
How to use DIRAB 10MG TABLET
Take DIRAB 10MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will fix the appropriate dose and duration for you, based on your age, body weight and disease condition.
Warning & Precautions
Pregnancy
There is no information available on the use of DIRAB 10MG TABLET in pregnant women. Contact your doctor before taking DIRAB 10MG TABLET.
Breastfeeding
DIRAB 10MG TABLET can be used safely in breastfeeding women. Contact your doctor before taking it.
Driving and Using Machines
There is no information available to suggest that DIRAB 10MG TABLET affects the ability to drive or use machines.
Allergy
Do not take DIRAB 10MG TABLET if you are allergic to Dexrabeprazole or other ingredients of this medicine.
Others
Before taking DIRAB 10MG TABLET, inform your doctor if you:
- have gastric cancer
Interactions
A. Drug - Drug interactions:
Before taking DIRAB 10MG TABLET, inform your doctor if you are taking any of the following medicine:
- ketoconazole and itraconazole (medicines used to manage fungal infections)
- diazepam (a medicine used to manage seizure, anxiety)
- phenytoin (a medicine used to manage seizure)
- warfarin (a medicine used to manage or manage blood clots)
Overdosage:
If you or anyone else accidentally take too much of DIRAB 10MG TABLET, Consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Dexrabeprazole |
| Pharmacological Category | : | Proton Pump Inhibitor (PPI) |
| Therapeutic Indication | : | Acid peptic disease, Gastro esophageal reflux disease, Gastric and duodenal ulcers, Erosive esophagitis, Zollinger-Ellison syndrome |
| Dosage Forms | : | Tablet |
More Information
- Keep out of reach of children
- Store below 30°C
FAQs About DIRAB 10MG TABLET
What is DIRAB 10MG TABLET used for?
DIRAB 10MG TABLET is used to manage acid peptic disease, Gastro esophageal reflux disease, gastric and duodenal ulcers, erosive esophagitis and Zollinger-Ellison syndrome. Contact your doctor before taking it.
What if I forget to take a dose of DIRAB 10MG TABLET?
If you have missed a dose of DIRAB 10MG TABLET, take it as soon as you remember. But if it is almost time for your next dose, you can skip the missed dose and take the next scheduled dose. Do not take double dose to make up for your missed one as this may increase the chances of having side effects.
Is DIRAB 10MG TABLET safe in pregnancy?
There is no information available on the use of DIRAB 10MG TABLET in pregnant women. Inform your doctor if you are pregnant or are planning for pregnancy before taking it.
What does DIRAB 10MG TABLET do the body?
DIRAB 10MG TABLET is a Proton Pump Inhibitor (PPI) works by decreasing gastric acid secretion by inhibiting an enzyme (protein) called H+/K+-ATPase on the gastric parietal cells (responsible for gastric acid secretion).
Can I use DIRAB 10MG TABLET while breast feeding?
DIRAB 10MG TABLET is safe in breastfeeding women and there is no increase in side effects in the infants or the possibility of harm to the breastfed infants is expected to be rare. Patients should follow the advice of the doctor before taking it.
References
1. KD Tripathi. Drugs for Peptic ulcer and Gastroesophageal Reflux Disease. Essentials of Medical Pharmacology. 7th edition. 2013. Page- 653.
2. Bethesda (MD). Dexrabeprazole. NIH National Library of Medicine, National Center for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 19th December 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Dexrabeprazole
3. Antunes C, Aleem A, Curtis SA. Gastroesophageal Reflux Disease. NIH National Library of Medicine, National Center for Biotechnology Information. StatPearls. July 2022. [Accessed on 19th December 2022] https://www.ncbi.nlm.nih.gov/books/NBK441938/
4. Kanakia R, Jain S. Ten mg dexrabeprazole daily is as effective as 20 mg rabeprazole daily. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central. July 2008. [Accessed on 19th December 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731293/
5. Stallion laboratories Pvt. Ltd. Dexrabeprazole. [Accessed on 19th December 2022] https://www.nafdac.gov.ng/wp-content/uploads/Files/SMPC/a_v5/PHRIX-SmPc.pdf
6. FARODEX (Dexrabeprazole). Faromed Lifesciences. [Accessed on 19th December 2022] https://faromed.at/farodex.php
7. RABODEX-10 (Dexrabeprazole 10mg). Solitaire Pharmacia Pvt Ltd. [Accessed on 19th December 2022] https://www.solitairepharmacia.co.in/dexrabeprazole-10-mg-5520221.html
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